BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0209.0019.p         (313 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

MA2021 [S] COG3391 Uncharacterized conserved protein Mac Methano...    77   7e-14
MA3842_1 [S] COG3391 Uncharacterized conserved protein Mac Metha...    60   5e-09

>MA2021 [S] COG3391 Uncharacterized conserved protein Mac Methanosarcina
           acetivorans str.C2A
          Length = 341

 Score = 76.6 bits (187), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 82/275 (29%), Positives = 118/275 (42%), Gaps = 32/275 (11%)

Query: 32  VSAPPVLEFDADGNLLRSWGGPGDGYEWVGREHGIEVDERGFVWIGGNADNDNA-ILKFT 90
           +S   + +F++ G  +  W     G   +   +GI VD  G V++   AD  N  I KF 
Sbjct: 69  ISNHRIQKFNSTGGYITQWDSSRSGNRKLFSPYGIAVDSSGNVYV---ADTGNKRIQKFN 125

Query: 91  LDGKFVAQIGSIAPSKGSNDTTQLGKPAETAIDKEANEIYVADGYGNRRVIVFDATTGAY 150
             G ++ Q GS+    G     Q   P   A+D   N +YV D  GN R+  F++T G Y
Sbjct: 126 GTGGYLTQWGSLGSGNG-----QFIYPHGVAVDSSGN-VYVTDA-GNNRIQKFNST-GGY 177

Query: 151 KRHWGAYGNKPDDAKQPPYDPKAQVAQQFGNPVHCVKIANDGLVYVCDRINNRIQVFRKD 210
              WG+YG+                  QF +P   V + + G VYV D  NNRIQ F   
Sbjct: 178 LTQWGSYGSGNG---------------QFNDP-EGVAVDSSGNVYVVDSDNNRIQKFNGT 221

Query: 211 GSFVKEFFFEKSTLGNGAVWDIALWPDPKQTYLLSADGENNEIRIIRRDDGAVVGSFGRN 270
           G ++ ++    S  GNG               +  AD  N  I+     +G  +  +  +
Sbjct: 222 GGYLTQWGSYGS--GNGQFLLPCGIAVDSSGNVYVADDFNQRIQKFN-SNGRYLTQWDSS 278

Query: 271 GRNAGQFHWVHALAVDARGNVYTAEVDTGKRIQKF 305
               GQ +    +AVD+ GNVY AE     RIQKF
Sbjct: 279 RSGNGQIYDPTGIAVDSSGNVYVAESGY-SRIQKF 312



 Score = 76.3 bits (186), Expect = 1e-13,   Method: Compositional matrix adjust.
 Identities = 80/261 (30%), Positives = 113/261 (43%), Gaps = 30/261 (11%)

Query: 45  NLLRSWGGPGDGYEWVGREHGIEVDERGFVWIGGNADNDNAILKFTLDGKFVAQIGSIAP 104
           N +  WG  G          G+ VD  G V++     +++ I KF   G ++ Q  S   
Sbjct: 35  NFVTKWGSYGSDSGQFICPIGVAVDSSGNVYV--TEISNHRIQKFNSTGGYITQWDS--- 89

Query: 105 SKGSNDTTQLGKPAETAIDKEANEIYVADGYGNRRVIVFDATTGAYKRHWGAYGNKPDDA 164
           S+  N   +L  P   A+D   N +YVAD  GN+R+  F+ T G Y   WG+ G+     
Sbjct: 90  SRSGN--RKLFSPYGIAVDSSGN-VYVADT-GNKRIQKFNGT-GGYLTQWGSLGSGNGQF 144

Query: 165 KQPPYDPKAQVAQQFGNPVHCVKIANDGLVYVCDRINNRIQVFRKDGSFVKEFFFEKSTL 224
             P                H V + + G VYV D  NNRIQ F   G ++ ++    S  
Sbjct: 145 IYP----------------HGVAVDSSGNVYVTDAGNNRIQKFNSTGGYLTQWGSYGS-- 186

Query: 225 GNGAVWDIALWPDPKQTYLLSADGENNEIRIIRRDDGAVVGSFGRNGRNAGQFHWVHALA 284
           GNG   D           +   D +NN I+      G  +  +G  G   GQF     +A
Sbjct: 187 GNGQFNDPEGVAVDSSGNVYVVDSDNNRIQKF-NGTGGYLTQWGSYGSGNGQFLLPCGIA 245

Query: 285 VDARGNVYTAEVDTGKRIQKF 305
           VD+ GNVY A+ D  +RIQKF
Sbjct: 246 VDSSGNVYVAD-DFNQRIQKF 265


>MA3842_1 [S] COG3391 Uncharacterized conserved protein Mac Methanosarcina
           acetivorans str.C2A
          Length = 318

 Score = 60.5 bits (145), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 67/224 (29%), Positives = 97/224 (43%), Gaps = 32/224 (14%)

Query: 84  NAILKFTLDGKFVAQIGSIAPSKGSNDTTQLGKPAETAIDKEANEIYVADGYGNRRVIVF 143
           +A +       FV  IGS     GSN   Q   P     D   N IYVAD  GN R+ +F
Sbjct: 25  SAFITHAASYNFVKVIGS--SGTGSN---QFSSPKYATTDSSGN-IYVADT-GNNRIEIF 77

Query: 144 DATTGAYKRHWGAYGNKPDDAKQPPYDPKAQVAQQFGNPVHCVKIANDGLVYVCDRINNR 203
           D     Y   WG+ G+         Y P        GN            +YV D  N+R
Sbjct: 78  DKNFN-YIDKWGSGGS----GNGQFYTPNGVAVDSMGN------------IYVADYNNHR 120

Query: 204 IQVFRKDGSFVKEFFFEKSTLGNG-AVWDIALWPDPKQTYLLSADGENNEIRIIRRDDGA 262
           +Q     G ++ +   + ST+G+G + + + L  D      +S D  +N I  + +D G 
Sbjct: 121 VQKLDSTGVYISQC--DSSTIGDGLSFYPVDLAVDSLDNVYVS-DSRSNRIVKLNKD-GN 176

Query: 263 VVGSFGRNGRNAGQFHWVHALAVDARGNVYTAEVDTG-KRIQKF 305
            +  +G  G +  QF+    +AVD+ GN+Y   VD+G  RI KF
Sbjct: 177 YLTQWGSKGASRNQFNDPEGIAVDSSGNIYV--VDSGNSRIMKF 218



 Score = 59.7 bits (143), Expect = 9e-09,   Method: Compositional matrix adjust.
 Identities = 44/133 (33%), Positives = 58/133 (43%), Gaps = 24/133 (18%)

Query: 84  NAILKFTLDGKFVAQIGSIAPSKGSNDTTQLGKPAETAIDKEANEIYVADGYGNRRVIVF 143
           N I+K   DG ++ Q GS   S+      Q   P   A+D   N IYV D  GN R++ F
Sbjct: 166 NRIVKLNKDGNYLTQWGSKGASR-----NQFNDPEGIAVDSSGN-IYVVDS-GNSRIMKF 218

Query: 144 DATTGAYKRHWGAYGNKPDDAKQPPYDPKAQVAQQFGNPVHCVKIANDGLVYVCDRINNR 203
           D T G Y   WG  G +    + P                H + I + G +YV D  N R
Sbjct: 219 DGT-GTYLTEWGTPGQEDGQFRSP----------------HGIAIDSSGAIYVTDTGNRR 261

Query: 204 IQVFRKDGSFVKE 216
           IQ F   GS+V +
Sbjct: 262 IQKFDSTGSYVTK 274