BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0207.0001.p (815 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3217 [T] COG2114 Adenylate cyclase, family 3 (some proteins co... 130 2e-29 all1904_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins... 129 2e-29 SMa0579 [T] COG2114 Adenylate cyclase, family 3 (some proteins c... 121 7e-27 alr2266_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins... 117 1e-25 all1118_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins... 115 5e-25 >PA3217 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Pae Pseudomonas aeruginosa Length = 463 Score = 130 bits (326), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 76/213 (35%), Positives = 121/213 (56%), Gaps = 5/213 (2%) Query: 594 RRLERFLAPQVAQLIASSDNPEGLLDSHRREVTVVFCDLRGFTAFTEATEPEEAMNVLRE 653 R L ++L+PQV ++I S L ++ R+++TV F D+RGFT +E E E ++L Sbjct: 198 RNLAKYLSPQVWEMIFSGKKSVRL-ETQRKKLTVFFSDIRGFTELSEELEAEALTDLLNN 256 Query: 654 YHAALGKLIFKYEGTLDKYAGDGVMILFNAP-IQLADHTA-RAVKMAVEMRDTVGPLTEK 711 Y + K+ KY GT+DK+ GD VM+ F P Q A A AV M + MR + L ++ Sbjct: 257 YLNEMSKIALKYGGTIDKFVGDCVMVFFGDPSTQGAKKDAVAAVSMGIAMRKHMKVLRQQ 316 Query: 712 WRNRG--HSLGFGIGIALGYATLGQVGFEQRLEYAAIGSVTNLASRLCGEAKAGQIVVSR 769 WR +G L +GI GY T+G G + R++Y IG NLASRL ++AG+I++S Sbjct: 317 WRAQGITKPLEIRMGINTGYCTVGNFGADTRMDYTIIGREVNLASRLESASEAGEILISH 376 Query: 770 RVYGMVEAYVEGRAIDDLVLKGFNHPILAAEIL 802 Y +++ + R + +KGF+ P+ +++ Sbjct: 377 ETYSLIKDVIMCRDKGQIAVKGFSRPVQIYQVV 409 >all1904_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Nos Nostoc sp. PCC 7120 Length = 296 Score = 129 bits (325), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 70/218 (32%), Positives = 123/218 (56%), Gaps = 5/218 (2%) Query: 596 LERFLAPQVAQLIASSDNPEGLLDSHRREVTVVFCDLRGFTAFTEATEPEEAMNVLREYH 655 + R++ ++A+ + D+ + L R+EV+++F D+RG+T TE E EE +++L EY Sbjct: 9 MYRYMTQELAEELLKLDDAK--LGGDRKEVSILFSDIRGYTTLTENLEAEEVVSMLNEYF 66 Query: 656 AALGKLIFKYEGTLDKYAGDGVMILFNAPIQLADHTARAVKMAVEMRDTVGPLTEK-WRN 714 ++ + +FK++GTLDKY GD +M +F +P+ L +H AVK ++EMR + +K + Sbjct: 67 ESMVEAVFKHKGTLDKYIGDAIMAVFGSPLPLEEHAWMAVKTSIEMRHRLQEFNQKRYAA 126 Query: 715 RGHSLGFGIGIALGYATLGQVGFEQRLEYAAIGSVTNLASRLCGEAK--AGQIVVSRRVY 772 + GIGI G +G +R+E+ AIG NL SRL +K I++S + Sbjct: 127 NKPRINIGIGINSDTVISGNIGSSKRMEFTAIGDGVNLGSRLESVSKQYGCDIILSDNTF 186 Query: 773 GMVEAYVEGRAIDDLVLKGFNHPILAAEILRWKGEPSA 810 + + R +D + +KG N P+ E++ + +P A Sbjct: 187 KPCQENIWARELDFIRVKGRNEPVSIYELIGLRSDPIA 224 >SMa0579 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Sme Sinorhizobium meliloti Length = 809 Score = 121 bits (303), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 66/216 (30%), Positives = 112/216 (51%), Gaps = 5/216 (2%) Query: 595 RLERFLAPQVAQLIASSDNPEGLLDSHRREVTVVFCDLRGFTAFTEATEPEEAMNVLREY 654 +L ++LAPQV I S + ++S R+++T+ F D+ FT T+ E EE +L +Y Sbjct: 549 KLAKYLAPQVYNSIFSGKQ-DVRIESRRKKLTICFSDIAAFTETTDKMESEELTQLLNQY 607 Query: 655 HAALGKLIFKYEGTLDKYAGDGVMILFNAPIQ--LADHTARAVKMAVEMRDTVGPLTEKW 712 + K+ + T+DKY GD +++ F P + + V MA+ M++ +G L E W Sbjct: 608 LTEMSKIALSFGATIDKYVGDAILMFFGDPETRGIREDAIACVSMALAMQERMGELGETW 667 Query: 713 RNRG--HSLGFGIGIALGYATLGQVGFEQRLEYAAIGSVTNLASRLCGEAKAGQIVVSRR 770 R+ G L IGI Y T+G G E R++Y IG NLA+RL EA G +++S Sbjct: 668 RSVGIEMPLRCRIGIHTDYCTVGNFGSEDRMDYTIIGGAVNLAARLEEEAAPGSVLISYE 727 Query: 771 VYGMVEAYVEGRAIDDLVLKGFNHPILAAEILRWKG 806 + V+ + + ++G +P+ ++ +K Sbjct: 728 TFAQVKDLIHCEETGRVQIRGIAYPVATYRVVDFKA 763 >alr2266_3 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Nos Nostoc sp. PCC 7120 Length = 296 Score = 117 bits (293), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 69/224 (30%), Positives = 120/224 (53%), Gaps = 5/224 (2%) Query: 596 LERFLAPQVAQLIASSDNPEGLLDSHRREVTVVFCDLRGFTAFTEATEPEEAMNVLREYH 655 + R+L P VA+ + + + L+ R+EVTV+F D+RG+T TE E +++L +Y Sbjct: 9 MYRYLTPHVAEQVMAL-GEDALMVGERKEVTVLFSDIRGYTTLTENLGAAEVVSLLNQYF 67 Query: 656 AALGKLIFKYEGTLDKYAGDGVMILFNAPIQLA-DHTARAVKMAVEMRDTVGPLTEKWRN 714 + + +F YEGTLDK+ GD +M +F AP+ L +H +AV+ A++MR + ++ Sbjct: 68 ETMVEAVFNYEGTLDKFIGDALMAVFGAPLPLTENHAWQAVQSALDMRQRLKEFNQRRII 127 Query: 715 RGH-SLGFGIGIALGYATLGQVGFEQRLEYAAIGSVTNLASRLCGEAK--AGQIVVSRRV 771 + + GIGI+ G G +G +R++Y IG NL+SRL K I++S Sbjct: 128 QAQPQIKIGIGISSGEVVSGNIGSHKRMDYTVIGDGVNLSSRLETVTKEYGCDIILSEFT 187 Query: 772 YGMVEAYVEGRAIDDLVLKGFNHPILAAEILRWKGEPSAEAAAE 815 Y + + R +D + +KG + + E++ + P + E Sbjct: 188 YQLCSDRIWVRQLDKIRVKGKHQAVNIYELISDRSTPLDDNTQE 231 >all1118_2 [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) Nos Nostoc sp. PCC 7120 Length = 322 Score = 115 bits (288), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 70/208 (33%), Positives = 108/208 (51%), Gaps = 4/208 (1%) Query: 596 LERFLAPQVAQLIASSDNPEGL-LDSHRREVTVVFCDLRGFTAFTEATEPEEAMNVLREY 654 L R+L +V I + P GL L RR+VT++F DLRGF+A +E PE+ + +L Y Sbjct: 1 LGRYLTDEVLANIL--ETPSGLKLGGERRKVTLLFSDLRGFSAMSEQLSPEQVVQILNLY 58 Query: 655 HAALGKLIFKYEGTLDKYAGDGVMILFNAPIQLADHTARAVKMAVEMRDTVGPLTEKWRN 714 + +I +Y+GT++++ GDG+ I+F API D + RA+ A+ M+ + + K Sbjct: 59 LGVMTDVINQYKGTINEFIGDGIFIMFGAPICRPDDSQRAIACAIAMQRAMQQVNAKTHQ 118 Query: 715 RG-HSLGFGIGIALGYATLGQVGFEQRLEYAAIGSVTNLASRLCGEAKAGQIVVSRRVYG 773 L GIGI G G +G ++R +Y IGS NLA+R+ GQI++S Sbjct: 119 MNLPQLEMGIGINTGEVVAGNIGSQKRAQYTVIGSHVNLAARIETYTVGGQILISENTRQ 178 Query: 774 MVEAYVEGRAIDDLVLKGFNHPILAAEI 801 ++ + KG PI EI Sbjct: 179 DANTDLQIAGQMQIEPKGIKEPITIYEI 206