BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0205.0011.p (549 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4198 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ... 680 0.0 mlr7293 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid... 627 e-179 mlr6974 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid... 517 e-146 DR0336 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ... 375 e-103 VNG0162G [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-aci... 285 2e-76 >PA4198 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Pae Pseudomonas aeruginosa Length = 540 Score = 680 bits (1755), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/533 (59%), Positives = 397/533 (74%), Gaps = 2/533 (0%) Query: 8 YSIGLDKTPANYVPLSPLSFLARSAAVYPDHISAVYEGRSFTWKATYERCRRFASYLAGH 67 + GL N++ L+PLSF+ R+A+VYP + + ++ W TY+RCRR AS LAG Sbjct: 4 FEQGLAPAAVNHIALTPLSFIERTASVYPHYPAVIHGNIRRDWAQTYQRCRRLASALAGR 63 Query: 68 GIGHGDTVAAMLPNIPAMNELHFAVPMTGAVLNALNIRLDAASIAFQLDHGGARIILVDP 127 GIG GDTVA MLPNIP M E H+ VPM GAVLN LN+RLDA +IAF L HG A++++ D Sbjct: 64 GIGQGDTVAVMLPNIPEMLEAHYGVPMIGAVLNTLNVRLDAEAIAFMLQHGEAKVLITDY 123 Query: 128 EFSNVIAEALSLMKGTRPFVIDVDDAAFAGGKRIGEIEYEAAVAAGDPAFTERPPADEWD 187 EF VI A+ ++ P V+DV+D + G+ +GE++YEA +A GDP F P DEW Sbjct: 124 EFHEVIHAAIGMLDHP-PLVVDVNDPEYGEGRPVGELDYEALLAEGDPQFAWEWPRDEWQ 182 Query: 188 AIALSYTSGTTGNPKGVVTHHRGAYLNAVSNILAGNLGQHPVYLWTLPMFHCNGWCFPWT 247 AI+L+YTSGTTGNPKGVV HHRGAYLNA+ N + ++GQHPVYLWTLPMFHCNGWC+PWT Sbjct: 183 AISLNYTSGTTGNPKGVVYHHRGAYLNALGNQMTWSMGQHPVYLWTLPMFHCNGWCYPWT 242 Query: 248 IAAAAGVNVCLRKVDPAKIFELIPRHGVTHMCGAPIVYNTLINAPDAPKGGKAKPVVGLI 307 + A AGV+VCLR+VDP K+ LI H V+H+CGAPIV N LIN PD+ K PV ++ Sbjct: 243 VTALAGVHVCLRRVDPQKVLTLIREHQVSHLCGAPIVLNALINMPDSAKAAIDHPVHAMV 302 Query: 308 AGAAPPVAVLEGAERIGIKLTHVYGLTEVYGPASVCAEQPGWDELSADVRAQLKRRQGVS 367 AGAAPP V+ E +GI++THVYGLTEVYGP +VCA WD+L + RA +K RQGV Sbjct: 303 AGAAPPAKVIGAVEEMGIRVTHVYGLTEVYGPVTVCAWHGEWDDLPLERRAAIKSRQGVR 362 Query: 368 YPLQEGVTVLDPETMREVPRDGETIGEVMFRGNIVMKGYLKNEKATQEAFAGGWFHTGDL 427 YP EGV V DP+T+ VPRDG++IGE+ RGN VMKGYLKN AT+EAFAGGWFHTGDL Sbjct: 363 YPTLEGVMVADPKTLEPVPRDGQSIGEIFMRGNTVMKGYLKNPSATEEAFAGGWFHTGDL 422 Query: 428 GVLDAHGYVIIKDRSKDIIISGGENVSSVEVEDILYKHPAVLFAAVVAKPDPKWGEVPCA 487 V GY+ I+DR KDIIISGGEN+S++E+E +LY+HPAVL AAVVA+PD KWGE PCA Sbjct: 423 AVCHPDGYIEIRDRLKDIIISGGENISTIELEGVLYRHPAVLEAAVVARPDEKWGETPCA 482 Query: 488 FIELK-DGAKATEAEIIAYCREHMSGFKTPKSVVFGVIPKTSTGKIQKFLLRN 539 FI LK D E+EI+A+CREH++ FK P++VVF +PKTSTGKIQK++LR Sbjct: 483 FITLKSDHQGLAESEIVAFCREHLAAFKIPRTVVFSELPKTSTGKIQKYVLRE 535 >mlr7293 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Mlo Mesorhizobium loti Length = 546 Score = 627 bits (1616), Expect = e-179, Method: Compositional matrix adjust. Identities = 315/540 (58%), Positives = 381/540 (70%), Gaps = 7/540 (1%) Query: 6 NQYSIGLDKTPANYVPLSPLSFLARSAAVYPDHISAVYEGRSFTWKATYERCRRFASYLA 65 N Y LD+ AN+ PL+PL++L R+A YPDHI+ ++ + +++ + R + AS L Sbjct: 3 NSYEQDLDRNAANHQPLTPLTYLERAAKTYPDHIAIIHGRQRISYRDFWRRSLKVASALQ 62 Query: 66 GHGIGHGDTVAAMLPNIPAMNELHFAVPMTGAVLNALNIRLDAASIAFQLDHGGARIILV 125 GIG GDTV ML N P M E HF VPMT AVL++LN RLDAA IAFQLDH ++++V Sbjct: 63 KRGIGKGDTVTVMLSNTPPMLEAHFGVPMTKAVLHSLNTRLDAAVIAFQLDHAETKVLIV 122 Query: 126 DPEFSNVIAEALSLMKGTRPFVIDVDDAAFAG------GKRIGEIEYEAAVAAGDPAFTE 179 D EFS V+ +AL L K T P VID DD +A G+RIG ++YE VA GD F Sbjct: 123 DREFSGVVRQALDLAKVT-PLVIDYDDPDYAADAPYPKGERIGALDYEDFVAGGDEDFAW 181 Query: 180 RPPADEWDAIALSYTSGTTGNPKGVVTHHRGAYLNAVSNILAGNLGQHPVYLWTLPMFHC 239 P DEWDAI+L+YTSGTTGNPKGVV HHRGA L A +N + + +H VYLWTLPMFHC Sbjct: 182 SMPDDEWDAISLNYTSGTTGNPKGVVYHHRGAALMAYTNTIHAGMAKHAVYLWTLPMFHC 241 Query: 240 NGWCFPWTIAAAAGVNVCLRKVDPAKIFELIPRHGVTHMCGAPIVYNTLINAPDAPKGGK 299 NGWCFPWT+A AG +VCLR V P I++ I HGVTH+CGAP+V + LINA D K Sbjct: 242 NGWCFPWTLAVQAGTHVCLRWVRPKPIYDAIADHGVTHLCGAPVVMSVLINARDEDKRTF 301 Query: 300 AKPVVGLIAGAAPPVAVLEGAERIGIKLTHVYGLTEVYGPASVCAEQPGWDELSADVRAQ 359 A+ V A A PP AVL G G +TH+YGLTE YGPA V WD+L+ R+ Sbjct: 302 AQTVTFNTAAAPPPEAVLSGMADAGFAVTHLYGLTETYGPAVVNEWHGEWDDLAKGERSA 361 Query: 360 LKRRQGVSYPLQEGVTVLDPETMREVPRDGETIGEVMFRGNIVMKGYLKNEKATQEAFAG 419 K RQGV Y EG+TV+DPETM+ P DGETIGEVMFRGNIVMKGYLKN KA+ EAFAG Sbjct: 362 KKARQGVRYAALEGLTVMDPETMQATPADGETIGEVMFRGNIVMKGYLKNRKASDEAFAG 421 Query: 420 GWFHTGDLGVLDAHGYVIIKDRSKDIIISGGENVSSVEVEDILYKHPAVLFAAVVAKPDP 479 GWFH+GDLGV+ GY+ +KDRSKDIIISGGEN+SS+EVED LYKHP+V VVA+ D Sbjct: 422 GWFHSGDLGVMHPDGYIQLKDRSKDIIISGGENISSIEVEDALYKHPSVASCGVVARHDD 481 Query: 480 KWGEVPCAFIELKDGAKATEAEIIAYCREHMSGFKTPKSVVFGVIPKTSTGKIQKFLLRN 539 KWGEVP A++ELK G A+EAEII +CR ++ FK PK+V+F IPKTSTGKIQKF LR Sbjct: 482 KWGEVPVAYVELKPGKTASEAEIIEHCRALLARFKVPKAVIFAEIPKTSTGKIQKFRLRE 541 >mlr6974 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Mlo Mesorhizobium loti Length = 541 Score = 517 bits (1331), Expect = e-146, Method: Compositional matrix adjust. Identities = 267/538 (49%), Positives = 344/538 (63%), Gaps = 12/538 (2%) Query: 5 QNQYSIGLDKTPANYVPLSPLSFLARSAAVYPDHISAVYEGRSFTWKATYERCRRFASYL 64 + Y L + AN V LSPLSFL R+ VY + Y TW T RCR A+ L Sbjct: 2 RQHYEAAL-RDDANCVALSPLSFLKRAELVYGARSAVTYGDVRRTWAQTGARCRSVAAGL 60 Query: 65 AGHGIGHGDTVAAMLPNIPAMNELHFAVPMTGAVLNALNIRLDAASIAFQLDHGGARIIL 124 A G+G GDTV+ + PNIP + ELH+AVP+ GAVLN +N RL+ ++A+ L H + +++ Sbjct: 61 AALGVGPGDTVSVLSPNIPELFELHYAVPLLGAVLNTINTRLEPETVAYILAHSDSTLVI 120 Query: 125 VDPEFSNVIAEALSLMKGTRPFVIDVDDAAFAGGKRIGEIEYEAAVAAGDPAFTERPPAD 184 D F+ ++ EA L T P V+DV DA GE YE A P P D Sbjct: 121 ADTAFAPLLREAFRLNGNTLP-VVDVVDAQAQASAEFGERSYEDL--AAHPPMGWELPKD 177 Query: 185 EWDAIALSYTSGTTGNPKGVVTHHRGAYLNAVSNILAGNLGQHPVYLWTLPMFHCNGWCF 244 EW A+AL+YTSGT+G PKGV+ HHRGAYL A+ I A L QHP YL +PMFHCNGW Sbjct: 178 EWQALALNYTSGTSGRPKGVIYHHRGAYLMAMGTIAAWALPQHPTYLSVVPMFHCNGWTH 237 Query: 245 PWTIAAAAGVNVCLRKVDPAKIFELIPRHGVTHMCGAPIVYNTLINAPDAPKGGKAKP-- 302 PW++A V R P K+ E + H VTHM APIV L + +G A+P Sbjct: 238 PWSMAIVGANMVFTRDASPGKLLEAMAAHRVTHMGAAPIVLQMLCDG----RGASAQPFN 293 Query: 303 --VVGLIAGAAPPVAVLEGAERIGIKLTHVYGLTEVYGPASVCAEQPGWDELSADVRAQL 360 + + AGA PP AVLE A ++G+ + VYGLTE YG S C Q W+ LS RA+ Sbjct: 294 PQIRVMTAGAPPPPAVLEKAAQMGLDVMQVYGLTETYGHISQCLWQDEWEALSVSARAEK 353 Query: 361 KRRQGVSYPLQEGVTVLDPETMREVPRDGETIGEVMFRGNIVMKGYLKNEKATQEAFAGG 420 + QGV++P+ E + V+D +T +VPRDG T GE+ RGN VMKGY K+ +T AF G Sbjct: 354 QAMQGVAFPMVEDIRVVDRDTGTDVPRDGLTQGEIAIRGNTVMKGYYKDATSTAAAFESG 413 Query: 421 WFHTGDLGVLDAHGYVIIKDRSKDIIISGGENVSSVEVEDILYKHPAVLFAAVVAKPDPK 480 WF +GD V+ GY+ I+DR KD+IISGGEN+SSVEVE +LY+HPA+ AAVVA+P PK Sbjct: 414 WFWSGDAAVVHPDGYIQIRDRLKDVIISGGENISSVEVESVLYRHPAISVAAVVARPHPK 473 Query: 481 WGEVPCAFIELKDGAKATEAEIIAYCREHMSGFKTPKSVVFGVIPKTSTGKIQKFLLR 538 WGE PCAF+EL++GA ATEAEIIA+CR +++ FK PK+VVFG +PKT+TGKIQKF+LR Sbjct: 474 WGESPCAFVELREGASATEAEIIAFCRANIAHFKAPKTVVFGPLPKTATGKIQKFILR 531 >DR0336 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Dra Deinococcus radiodurans Length = 524 Score = 375 bits (964), Expect = e-103, Method: Compositional matrix adjust. Identities = 229/538 (42%), Positives = 302/538 (56%), Gaps = 26/538 (4%) Query: 16 PANYVPLSPLSFLARSAAVYPDHISAVYE--GRSFTWKATYERCRRFASYLAGHGIGHGD 73 P N PL+PL+ + R +YPDH +AV E G FT++ R + A + G G G Sbjct: 2 PMN-TPLTPLTLVRRGLKLYPDH-TAVIEPGGPRFTYREWGRRIYQLARAIQAAGYG-GQ 58 Query: 74 TVAAMLPNIPAMNELHFAVPMTGAVLNALNIRLDAASIAFQLDHGGARIILVDPEFSNVI 133 VA + PN + VP G+VL LN RL FQL H R++LVD + + Sbjct: 59 HVAVLSPNTHGGLLTYAGVPWAGSVLVPLNTRLTPEEYEFQLRHAEVRLLLVDESLHDRV 118 Query: 134 AEALSLMKGTRPFVIDVDDAAFAGGKRIGEIEYEAAVAAGDPAFTERPPADEWDAIALSY 193 E + + G +V+ DA AG +EA +AA D + P DE I L++ Sbjct: 119 REVAAGL-GIEVWVMG--DARGAG------TAFEAKLAAQDDSPLPLPVQDENGTITLNF 169 Query: 194 TSGTTGNPKGVVTHHRGAYLNAVSNILAGNLGQHPVYLWTLPMFHCNGWCFPWTIAAAAG 253 TSGTT +PKGV+ HR LNA+ I Q VYL TLP FH NGW W+ Sbjct: 170 TSGTTSDPKGVMMTHRSTMLNAIETIYYFKADQDTVYLHTLPDFHANGWGGVWSPFGVGA 229 Query: 254 VNVCLRKVDPAKIFELIPRHGVTHMCGAPIVYNTLINAPDAPKGGKAKPVVGLI----AG 309 +V L V ++ I +HGVTH+C AP V + L + A+P+ I AG Sbjct: 230 THVTLPTVRADAAYDAIEQHGVTHLCAAPTVLSMLTDP------AHARPLSRQIRVATAG 283 Query: 310 AAPPVAVLEGAERIGIKLTHVYGLTEVYGPASVCAEQPGWDELSADVRAQLKRRQGVSYP 369 + P ++ +G +T VYGLTE +V +EL RA L +QGV Sbjct: 284 SPPHARIIADMNALGFHVTQVYGLTETSPLITVAELSAQQEELPTPRRAALIAKQGVEMI 343 Query: 370 LQEGVTVLDPETMREVPRDGETIGEVMFRGNIVMKGYLKNEKATQEAFAGGWFHTGDLGV 429 L V VLDPE +R VP DGET+GE+M RGN+VMKGY +NE+AT +A GGWFHTGD+ V Sbjct: 344 LAGEVEVLDPE-LRPVPGDGETLGEIMVRGNLVMKGYYRNEEATAKALEGGWFHTGDVAV 402 Query: 430 LDAHGYVIIKDRSKDIIISGGENVSSVEVEDILYKHPAVLFAAVVAKPDPKWGEVPCAFI 489 + G + I+DR+KD+IISGGEN+SSVEVE +LY HPAV A VVA P KWGEVPCAFI Sbjct: 403 VHPDGRIEIRDRNKDVIISGGENISSVEVEGVLYAHPAVREAVVVAMPHEKWGEVPCAFI 462 Query: 490 ELKDGAKATEAEIIAYCREHMSGFKTPKSVVF-GVIPKTSTGKIQKFLLRNQVGSAKA 546 L G + T ++ A+ REH++GFK PK F +PKT++GK QKF+LR ++ KA Sbjct: 463 ALHQGQEVTPEDLTAHVREHLAGFKVPKHYEFRDDLPKTASGKFQKFILRAELWQGKA 520 >VNG0162G [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Hbs Halobacterium sp. NRC-1 Length = 600 Score = 285 bits (729), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 200/531 (37%), Positives = 270/531 (50%), Gaps = 23/531 (4%) Query: 21 PLSPLSFLARSAAVYPDHISAV-YEGRSFTWKATYERCRRFASYLAGHGIGHGDTVAAML 79 PL F+ R+ Y D + V GR +T+ +R RF++ L GI GD VA + Sbjct: 66 PLLVTDFIDRARTYYGDETAVVATTGRRYTYSELADRADRFSAVLQAAGIDSGDRVAVLD 125 Query: 80 PNIPAMNELHFAVPMTGAVLNALNIRLDAASIAFQLDHGGARIILVDPEFSNVIAEALSL 139 PN E + GA+ LN RL A+ L GA I D +++ + EA+ Sbjct: 126 PNTHYHLEAAYGAMQLGAIHTPLNYRLTPDDYAYILADAGADAIYADAAYADRV-EAVRD 184 Query: 140 MKGTRPFVIDVDDAAFAGGKRIGEIEYEAAVAAGDPAFTERPPADEWDAIALSYTSGTTG 199 T F+ D D AA G + + A +RP E D I ++YTSGTTG Sbjct: 185 QIPTTTFITD-DPAAVDGDWQDADALLADADPD----DYDRPDMAEDDVITINYTSGTTG 239 Query: 200 NPKGVVTHHRGAYLNAVSNILAGNLGQHPVYLWTLPMFHCNGWCFPWTIAAAAGVNVCLR 259 +PKGV HR ++A+ + YLWTLPMFH NGW + I A +VC R Sbjct: 240 DPKGVCRTHRNEVVHALLLSTHHTITDTDTYLWTLPMFHANGWGHIFAITGAGATHVCTR 299 Query: 260 KVDPAKIFELIPRHGVTHMCGAPIVYNTLIN---APDAPKGGKAKPVVGLIAGAAPPVAV 316 VD A +F+ I V+++C AP V N L++ A D G A V AG+APP A Sbjct: 300 GVDAASVFDTIQAEAVSYLCAAPTVLNMLLDYHEAHDVAATGDADVRVA-TAGSAPPEAT 358 Query: 317 LEGAER-IGIKLTHVYGLTEVYGPASVCAEQPGWDELSADVRAQLKRRQGVSYPLQEGVT 375 + E + L HVYG TE GP ++ RA +++RQG+ L + Sbjct: 359 IRAVESALDWSLMHVYGATET-GPLIATSDADRLLAAGGGSRAAMQKRQGIGL-LGTELR 416 Query: 376 VLDPETMREVPRDGETIGEVMFRGNIVMKGYLKNEKATQEAFA---GGWFHTGDLGVLDA 432 V+D E +VPRD ETIGE++ GN VM Y AT+ AF G+FH GD V+D Sbjct: 417 VVD-EHGNDVPRDNETIGEIVVSGNQVMDRYWNKPDATERAFTDRVDGYFHMGDFAVVDD 475 Query: 433 HGYVIIKDRSKDIIISGGENVSSVEVEDILYKHPAVLFAAVVAKPDPKWGEVPCAFIELK 492 G+V I DR KDIIISGGEN+SS+E+ED L++H AV AVV P WGE P AF+ Sbjct: 476 TGFVSILDRKKDIIISGGENISSIELEDTLFEHDAVGEVAVVPSPHDDWGETPKAFVVPA 535 Query: 493 DGAK----ATEAEIIAYCREHMSGFKTPKSVVF-GVIPKTSTGKIQKFLLR 538 G T ++ Y R ++ FKT + V F +P T+TGK+QK+ LR Sbjct: 536 SGDPNNPGVTTTALVEYTRAELASFKTVRRVEFVDELPTTATGKVQKYELR 586