BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0203.0046.p         (346 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

mll2315 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet...   194   4e-49
BMEI0017 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene te...   190   5e-48
DR0611 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetr...   181   2e-45
AGl1468 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet...   130   5e-30
TM1724 [IQR] COG1028 Dehydrogenases with different specificities...   120   3e-27

>mll2315 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene
           tetrahydromethanopterin reductase and related
           flavin-dependent oxidoreductases Mlo Mesorhizobium loti
          Length = 340

 Score =  194 bits (492), Expect = 4e-49,   Method: Compositional matrix adjust.
 Identities = 94/107 (87%), Positives = 99/107 (92%)

Query: 1   MKKIGFLSFGHWTPSPQSQARSAADVLLQSIDLAVAAEELGADGAYFRVHHFARQLASPF 60
           MKKIGFLSFGHWTPS QSQ RSA+D LLQSIDLAVAAE+LGADGAYFRVHHFARQLASPF
Sbjct: 1   MKKIGFLSFGHWTPSSQSQVRSASDALLQSIDLAVAAEQLGADGAYFRVHHFARQLASPF 60

Query: 61  PLLAAVGARTSRIEIGTAVIDMRYENPLYMIEDAGAADLXAGQRTTV 107
           PLLAAVGA+TSRIEIGTAVIDMRYENPLYM EDAGAAD+ AG R  +
Sbjct: 61  PLLAAVGAKTSRIEIGTAVIDMRYENPLYMAEDAGAADIIAGGRLQL 107


>BMEI0017 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene
           tetrahydromethanopterin reductase and related
           flavin-dependent oxidoreductases Bme Brucella melitensis
          Length = 340

 Score =  190 bits (482), Expect = 5e-48,   Method: Compositional matrix adjust.
 Identities = 90/107 (84%), Positives = 97/107 (90%)

Query: 1   MKKIGFLSFGHWTPSPQSQARSAADVLLQSIDLAVAAEELGADGAYFRVHHFARQLASPF 60
           MKKIGFLSFGHW+P+PQS  RSA D LLQSIDLAVAAEELGADGAYFRVHHFARQLASPF
Sbjct: 1   MKKIGFLSFGHWSPAPQSGTRSAGDTLLQSIDLAVAAEELGADGAYFRVHHFARQLASPF 60

Query: 61  PLLAAVGARTSRIEIGTAVIDMRYENPLYMIEDAGAADLXAGQRTTV 107
           PLLAA+GA+TSRIEIGTAVIDMRYENP YM+EDAGAADL +  R  +
Sbjct: 61  PLLAAIGAKTSRIEIGTAVIDMRYENPFYMVEDAGAADLISKGRLQL 107


>DR0611 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene
           tetrahydromethanopterin reductase and related
           flavin-dependent oxidoreductases Dra Deinococcus
           radiodurans
          Length = 338

 Score =  181 bits (459), Expect = 2e-45,   Method: Compositional matrix adjust.
 Identities = 88/107 (82%), Positives = 93/107 (86%)

Query: 1   MKKIGFLSFGHWTPSPQSQARSAADVLLQSIDLAVAAEELGADGAYFRVHHFARQLASPF 60
           MKKIGFLSFGHW P PQS+ RSA DVL QSIDLAVAAEELGADGAYFRVHHFA+QLASPF
Sbjct: 1   MKKIGFLSFGHWNPHPQSRTRSAGDVLRQSIDLAVAAEELGADGAYFRVHHFAQQLASPF 60

Query: 61  PLLAAVGARTSRIEIGTAVIDMRYENPLYMIEDAGAADLXAGQRTTV 107
           PLLAAVGA+TS IEIGT VIDMRYENP  M E+AGAADL AG R  +
Sbjct: 61  PLLAAVGAKTSNIEIGTGVIDMRYENPFSMAENAGAADLIAGGRLQL 107


>AGl1468 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene
           tetrahydromethanopterin reductase and related
           flavin-dependent oxidoreductases Atu Agrobacterium
           tumefaciens strain C58 (Cereon)
          Length = 306

 Score =  130 bits (326), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 61/73 (83%), Positives = 66/73 (90%)

Query: 35  VAAEELGADGAYFRVHHFARQLASPFPLLAAVGARTSRIEIGTAVIDMRYENPLYMIEDA 94
           +AAEELGADGAYFRVHHFARQLASPFPLLAAVGART +IEIGT VIDMRYENP YM+EDA
Sbjct: 1   MAAEELGADGAYFRVHHFARQLASPFPLLAAVGARTKKIEIGTGVIDMRYENPFYMVEDA 60

Query: 95  GAADLXAGQRTTV 107
           G+ADL AG R  +
Sbjct: 61  GSADLIAGGRLQL 73


>TM1724 [IQR] COG1028 Dehydrogenases with different specificities (related
           to short-chain alcohol dehydrogenases) Tma Thermotoga
           maritima
          Length = 246

 Score =  120 bits (302), Expect = 3e-27,   Method: Compositional matrix adjust.
 Identities = 77/228 (33%), Positives = 117/228 (51%), Gaps = 3/228 (1%)

Query: 114 GNGRAMSVLFAREGASVACLDVNKDAADDTVAQITKEGGKAFTDVVDVSDVAAIVPAVER 173
           G G+A ++LFA+EGA+V   D++K+  D  V +     GK    V++V+D   I   VE+
Sbjct: 16  GIGKATTLLFAQEGATVIAGDISKENLDSLVKEAEGLPGKVDPYVLNVTDRDQIKEVVEK 75

Query: 174 CAQRLGGLDGLALNVGISSGLSLPKMTAEAWDRDYAVNVRSHMLFAQKALEVMAP--GGA 231
             Q+ G +D L  N GI+    L +M  E WD    VN++      Q  +  M     G+
Sbjct: 76  VVQKYGRIDVLVNNAGITRDALLVRMKEEDWDAVINVNLKGVFNVTQMVVPYMIKQRNGS 135

Query: 232 IILISSMASQRAGGRNPAYESSKAAQIALGRAIARAGEDKGIRCNVIAPGFMDTPMGRDA 291
           I+ +SS+           Y +SKA  I + +  A+    + IR N +APGF++TPM    
Sbjct: 136 IVNVSSVVGIYGNPGQTNYAASKAGVIGMTKTWAKELAGRNIRVNAVAPGFIETPMTEKL 195

Query: 292 SRRRSDRAVT-VPFGRQGTGWEVAYTALFLISNESSYVNAHTLFLDAG 338
             +  + A++ +P GR G   EVA   LFL S+ESSYV    + +D G
Sbjct: 196 PEKARETALSRIPLGRFGKPEEVAQVILFLASDESSYVTGQVIGIDGG 243