BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0200.0122.p (1059 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1597 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1142 0.0 SMa0875 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobi... 395 e-109 AGl494 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacteriu... 347 7e-95 alr5294 [V] COG0841 Cation/multidrug efflux pump Nos Nostoc sp. ... 322 2e-87 AGc3721 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacteri... 318 4e-86 >RSp1597 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1064 Score = 1142 bits (2955), Expect = 0.0, Method: Compositional matrix adjust. Identities = 587/1063 (55%), Positives = 756/1063 (71%), Gaps = 11/1063 (1%) Query: 4 LVRIALSRPYTFVVLAILLLIIGPLAALRTPTDIFPDIRIPVIGVVWQYTGLPPDQMSGR 63 +V++AL RP TF+VLA+L+L+ P +R TDIFP+I IPV ++W Y GLP +M+ R Sbjct: 3 IVQLALRRPLTFIVLALLILLATPFVLMRMATDIFPEIDIPVCSIIWNYNGLPAKEMADR 62 Query: 64 ITTPFQRALTTTVNDIEHIVANSYNGVGIIKIFFQPNVDIRTANAQVTAISQTLLKQMPP 123 I + +R+LTTTVNDIEHI + S GV IIK+FFQP +I+TA AQ+ ++SQ L+Q+PP Sbjct: 63 IVSVTERSLTTTVNDIEHIESQSLGGVSIIKVFFQPTANIQTALAQIVSVSQAQLRQLPP 122 Query: 124 GATPPLILNYSASTVPIIQVALSGEGLTEQNLADIGINQLRTPLVTVPGAAIPYPFGGKQ 183 G TPPL++ YSAS++PI+Q+ LS L+EQ L D +N LR L+TVPG A+P+P+GGK Sbjct: 123 GITPPLVIKYSASSIPILQLGLSSNTLSEQELNDAALNFLRPRLITVPGIAVPFPYGGKS 182 Query: 184 RQVQIDLNSTALQARGLSGQDVANALAAQNLITPVGTQKIGNFEYTINLNNSPLRLEELG 243 RQ+ +DL++ L A+GL+ D+ NA++AQNLI P GTQKI EY + LN +P + +L Sbjct: 183 RQITVDLDTQKLLAQGLTPTDIVNAVSAQNLILPAGTQKIDASEYAVALNGTPGTIAQLN 242 Query: 244 DLPIKQVNGAMVYVRDVASVRDGNPPQTNIIHVDGNRSVLMMVLKAGATSTLDIISGIKQ 303 +P++ NGA + + DVA+VRDG PQTN++ DG R VL+ +LK G STLDI+S I + Sbjct: 243 AMPVRTRNGATLVLGDVANVRDGFSPQTNVVRQDGQRGVLLSILKNGGASTLDIVSNIYK 302 Query: 304 KVIEVKDQMPDALKIGFIGDQSVFVRGAITGVAFEGVIAALLTSIMILLFLGSWRSTVII 363 + +P +KI + DQS+FV+ AI GV E +IAA LT+ MILLFLG+WRST II Sbjct: 303 LLPVAATALPQDIKITPLFDQSLFVKAAIEGVIREALIAACLTAAMILLFLGNWRSTAII 362 Query: 364 AVSIPLSVLGAIIMLSLIGETLNIMTLGGLALAVGILVDDATVTIENINYHLEQGKPVEQ 423 AVSIPLS+L +II+L L+GET+N+MTLGGLALAVGILVDDATVTIENI HL +GK Sbjct: 363 AVSIPLSILSSIIVLHLLGETINLMTLGGLALAVGILVDDATVTIENIERHLHEGKAPIT 422 Query: 424 SILDGANQIVTPAFVSLLCICIVFVPMFFLTGVARFLFVPMAEAVMFAMIWSFILSRTLV 483 +ILDGA +I PAFVS LCICIVFVPMFFLTGVAR+LFVPMAEAV+FAM+ S++LSRTLV Sbjct: 423 AILDGAAEIAVPAFVSTLCICIVFVPMFFLTGVARYLFVPMAEAVIFAMLASYVLSRTLV 482 Query: 484 PTMANYLLQAHVHHEGAPPKSRNPLVWFQRGFEARFERIRSGYRGLLAMALGHRTVFVSC 543 PT+ L+ H P P+ + + F ARFE +R Y +L L HR VF Sbjct: 483 PTLVMMLMTGHTEDAKKP----GPMRYIYQAFNARFEHMRGNYAAILGGLLEHRRVFALS 538 Query: 544 FLAVVAASFLLVPFLGRNFFPSVDAGNILMHVRTQVGTRVEETANQLADIQKAIRKLVP- 602 FL AS L LGR+FFP VDAG I +H+R G R+EETA +++ AIR ++P Sbjct: 539 FLGFCVASCALYLALGRDFFPDVDAGQIRLHMRAPSGLRIEETARLADEVEAAIRTIIPR 598 Query: 603 GEIETMTDNIGMPISGINMTYNNTGVIGPQDGDIQIRLKEGH-KPTEEHVRTLREQLPRL 661 E+ T+ DN+G+P SGIN++Y+N G IG DG+I I L+EG KP+ E+VR LRE+LP+ Sbjct: 599 NELATLLDNLGVPNSGINLSYSNAGTIGTLDGEILIALREGERKPSAEYVRRLREELPKR 658 Query: 662 FPGTSFAFLPADIVSQILNFGAPAPIDLQIRGANLEANFAYANKLLAGIKRIPGIADARI 721 FPG FAF PADIVSQILNFG P+ ID+Q GA++ AN A L I+RIPG D + Sbjct: 659 FPGVEFAFQPADIVSQILNFGLPSAIDVQFSGADVAANQQLAGILANRIRRIPGAVDTHV 718 Query: 722 QQSPNNPTFNIDVDRTRAQYVGLTERDVTNSLVVNLAGSSQVAPTYYLNPDNGVSYSIVM 781 Q + PT +++DRTR Q VGL RDV +L+V+L+ S Q +PT++LNP NGV Y + + Sbjct: 719 HQRFDQPTLAVNMDRTRIQQVGLQGRDVAQNLLVSLSSSFQTSPTFWLNPVNGVVYQVAV 778 Query: 782 QTPQYQIDSLSALQTLPIT-ATGNTQAP----ILGGIADIKRATSSAVVSQYDIQSLVQI 836 Q+PQY++DSL AL P+ A G P +LG + + A VVS YDI +V + Sbjct: 779 QSPQYRVDSLDALLRTPVAGAGGGATQPGGPQLLGNLVQVGPAVQPQVVSHYDITPVVDV 838 Query: 837 YATTQGRDLGGVATDVRKLIADTAKEVPKGSSVVLLGQVQTMNSAFTGLLFGLLGAVVLI 896 YA QGRDLG VA +V+K + + ++P+G+ + + GQV+TM S+F GL GL+ A+VL+ Sbjct: 839 YAAVQGRDLGAVAKEVQKAVDEIRPKLPRGAQITVRGQVRTMESSFVGLGVGLVMAIVLV 898 Query: 897 YFLIVVNFQSWSDPFVIITALPAALAGIVWMLFTTETTLSVPALTGAIMCMGVATANSVL 956 Y LIVVNFQSW DP +I+TALPAALAGI WMLF T TTLSVP+LTGAIM MGVATANS+L Sbjct: 899 YLLIVVNFQSWIDPLIIVTALPAALAGIAWMLFVTGTTLSVPSLTGAIMTMGVATANSIL 958 Query: 957 VISFARERYEELGDPVAAALEAGFVRFRPVLMTALAMIIGMAPMALGLGEGGEQNAPLGR 1016 +ISFARER E P+ AALEAG R RPVLMTALAMIIGM PMALGLGEG EQNAPLGR Sbjct: 959 LISFARERLHEGIAPMQAALEAGATRLRPVLMTALAMIIGMVPMALGLGEGAEQNAPLGR 1018 Query: 1017 AVIGGLIFATFATLMFVPVVFSMVHKKQGAKAAASSEIPHAAH 1059 AVIGGL+FAT +TL FVPVVF+ VH + +A P + Sbjct: 1019 AVIGGLLFATVSTLFFVPVVFASVHGRLQRRAGRRGTDPRGSE 1061 >SMa0875 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobium meliloti Length = 1065 Score = 395 bits (1015), Expect = e-109, Method: Compositional matrix adjust. Identities = 290/1048 (27%), Positives = 509/1048 (48%), Gaps = 33/1048 (3%) Query: 4 LVRIALSRPYTFVVLAILLLIIGPLAALRTPTDIFPDIRIPVIGVVWQYTGLPPDQMSGR 63 L RI+++ P ++ +++L++G + R D +P+ +PV+ V YTG P+ + Sbjct: 3 LTRISINHPVFATMMMVMILVLGLFSYGRLGVDHYPETDLPVVVVATTYTGASPESVESE 62 Query: 64 ITTPFQRALTTTVNDIEHIVANSYNGVGIIKIFFQPNVDIRTANAQVTAISQTLLKQMPP 123 I+ P + AL T + I+ I + SY G I+ + F+ +VD + A +V L + P Sbjct: 63 ISRPIEAALNT-IGGIDTITSESYEGRSIVVVQFEVDVDSQDAAQEVRDRVARLETKFPD 121 Query: 124 GATPPLILNYSASTVPIIQVALSGEGLTEQNLADIGINQLRTPLVTVPGAAIPYPFGGKQ 183 G P + Y I+ VA+S T + + + L + G G + Sbjct: 122 GVATPQVTRYKPEGQAILSVAVSSTSRTLPEITTLATRVINNRLSVISGVGQVSLIGSSE 181 Query: 184 RQVQIDLNSTALQARGLSGQDVANALAAQNLITPVGTQKIGNFEYTINLNNSPLRLEELG 243 RQV + ++ L A GL+ V A+ +N GT G + + + Sbjct: 182 RQVLVVVDPDRLGAYGLAVSTVIEAIRGENQDRAAGTLISGINQRIVTVEGRIANTSGFN 241 Query: 244 DLPIKQVNGAMVYVRDVASVRDGNPPQTNIIHVDGNRSVLMMVLKAGATSTLDIISGIKQ 303 + + Q NG VY+ +VA++ D T++ + G ++ + ++K +T+++ S +++ Sbjct: 242 RIIVAQRNGYPVYLSEVATILDTGAEVTSLANYQGQTTLGLHIVKVQGANTVEVASAVRR 301 Query: 304 KVIEVKDQM-PDALKIGFIGDQSVFVRGAITGVAFEGVIAALLTSIMILLFLGSWRSTVI 362 +V + ++ D +++ D S + ++ V V +L+ +++ +FL SWRSTVI Sbjct: 302 EVSALNAELTKDNVQLTITRDNSRPIASQVSQVQRTLVEGGVLSVLIVFIFLNSWRSTVI 361 Query: 363 IAVSIPLSVLGAIIMLSLIGETLNIMTLGGLALAVGILVDDATVTIENINYHLEQGKPVE 422 +++P+SV+G + +G TLNIMTL L+L++GIL+DDA V ENI HL+ GK Sbjct: 362 TGLTLPISVIGTFAAIYALGFTLNIMTLMALSLSIGILIDDAIVVRENITRHLQMGKDPV 421 Query: 423 QSILDGANQIVTPAFVSLLCICIVFVPMFFLTGVARFLFVPMAEAVMFAMIWSFILSRTL 482 ++ LDG N+I + LCI VF+P+ F+ G+ F+ V A++ S +S TL Sbjct: 422 RAALDGTNEIGLAVLSTTLCIVAVFLPVAFMGGLIGRFFLQFGVTVAVAVVISLFVSFTL 481 Query: 483 VPTMANYLLQAHVHHEGAPPKSRNPLVWFQRGFEARFERIRSGYRGLLAMALGHRTVFVS 542 P +++ R F+ FE + S YR ++ +R ++ Sbjct: 482 DPMLSSVWCDPQSQKTA----KRGFFGQLIERFDQWFEGLASRYRSVIYFTFDYRKTTIA 537 Query: 543 CFLAVVAASFLLVPFLGRNFFPSVDAGNILMHVRTQVGTRVEETANQLADIQKAIRKLVP 602 L + S LLVP +G F P D G + + + G ++ A ++ I++A+R Sbjct: 538 IVLGMFVVSLLLVPRIGTEFLPPPDQGEVSISLEANEGASLDYMAAKVGQIERALR---- 593 Query: 603 GEIETMTDNIGMPISGINMTYNNTGVIGPQDGDIQIRLKEGHKPTEEHVRTLREQLPRLF 662 E ++ SG +N V Q RLK T E + +R +L R+ Sbjct: 594 -EFNYVSSTYSTINSGEMRGFNKALVAVQLVHSSQRRLK-----TAETLGPIRRRLSRI- 646 Query: 663 PGTSFAFLPADIVSQILNFGAPAPIDLQIRGANLEANFAYANKLLAGIKRIPGIADARIQ 722 A L + + G+ P+ L I G E ++ + + + IPG + Sbjct: 647 -----AGLEISVGQRSEVVGSIKPLQLSILGDGDEELRRISDHITSVLAAIPGATEIESS 701 Query: 723 QSPNNPTFNIDVDRTRAQYVGLTERDVTNSLVVNLAGSSQVAPTYYLNPDNGVSYSIVMQ 782 PT + V R A +G++ + ++L +AG A + + +PD G ++ +V++ Sbjct: 702 IEKLRPTLAVRVRREAASDLGVSIATIGDTLRSLVAGD---AISVWNSPD-GETHDVVVR 757 Query: 783 TPQYQIDSLSALQTLPITAT--GNTQAPI---LGGIADIKRATSSAVVSQYDIQSLVQIY 837 P ++ + L+ LPI + PI L +AD+ +T+ A +++ D+ ++I Sbjct: 758 LPAAGRENAAQLRNLPIATARMDDNGKPIMVLLDQVADVVESTAPAQITRKDLSRDIRIS 817 Query: 838 ATTQGRDLGGVATDVRKLIADTAKEVPKGSSVVLLGQVQTMNSAFTGLLFGLLGAVVLIY 897 + +GR LG V D++ A T ++P G + G + + + L L AV+ IY Sbjct: 818 SNIEGRTLGDVVADLKA--AMTKMDIPVGFRISFGGDAENLTESTAYALQSLAMAVIFIY 875 Query: 898 FLIVVNFQSWSDPFVIITALPAALAGIVWMLFTTETTLSVPALTGAIMCMGVATANSVLV 957 ++ F S+ P II +P +L G++ L T +TL++ ++ G +M MG+ T N++L+ Sbjct: 876 IILASQFGSFIQPIAIIMTMPLSLMGVLLGLLFTGSTLNMFSMIGIMMLMGLVTKNAILL 935 Query: 958 ISFARERYEELGDPVAAALEAGFVRFRPVLMTALAMIIGMAPMALGLGEGGEQNAPLGRA 1017 + ++ E + +AG VR RP++MT LAMI GM P ALGLGEGG Q AP+ A Sbjct: 936 VDYSNLGVREGKSLRQSLADAGAVRLRPIVMTTLAMIFGMLPTALGLGEGGAQRAPMAHA 995 Query: 1018 VIGGLIFATFATLMFVPVVFSMVHKKQG 1045 +IGGLI +T +L+FVPVV + + G Sbjct: 996 IIGGLISSTLLSLVFVPVVLTYLDAFAG 1023 >AGl494 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1048 Score = 347 bits (891), Expect = 7e-95, Method: Compositional matrix adjust. Identities = 288/1051 (27%), Positives = 506/1051 (48%), Gaps = 50/1051 (4%) Query: 4 LVRIALSRPYTFVVLAILLLIIGPLAALRTPTDIFPDIRIPVIGVVWQYTGLPPDQMSGR 63 L RI+++ P ++ + LL++G + R D +P++ +PV+ VV Y G P+ + Sbjct: 3 LTRISVNHPVFATMMMVALLVMGAFSLQRLGLDQYPNVDVPVVVVVTSYPGATPETVEME 62 Query: 64 ITTPFQRALTTTVNDIEHIVANSYNGVGIIKIFFQPNVDIRTANAQVTAISQTLLKQMPP 123 +T P + AL + ++ + + SY G ++ F+ V A +V + P Sbjct: 63 VTRPVEDALNA-IGGLDEVTSTSYEGRSVVVAKFKLEVQSSAAAQEVRDKIAAIEANFPE 121 Query: 124 GATPPLILNYSASTVPIIQVALSGEGLTEQNLADIGINQLRTPLVTVPGAAIPYPFGGKQ 183 P+I + + PI+ +A+S L LA + ++ L TV G GG++ Sbjct: 122 DTKKPVISRFDPAAEPILSLAISSTSLDVPALATLAEQKVVRQLTTVAGIGQATLVGGRK 181 Query: 184 RQVQIDLNSTALQARGLSGQDVANALAAQNLITPVGTQKIGNFEYTINLNNSPLRLEELG 243 RQ+ + ++ T ++A G+ +V AL A N +P G+ E TI + + E L Sbjct: 182 RQIDVTIDETRMRALGIGVNEVVTALRAGNSNSPAGSVVDPVSERTIQIQSRIEEPEALL 241 Query: 244 DLPIKQVNGAMVYVRDVASVRDGNPPQTNIIHVDGNRSVLMMVLKAGATSTLDIISGIKQ 303 D+ + + G + +RDVA++ +G N +G ++ + ++K +T+ ++S +++ Sbjct: 242 DMVVARRGGVAILLRDVATLSEGAADAENRAIYNGQTALAIDIVKVQDANTVQVVSDVRK 301 Query: 304 KVIEVKDQM-PDALKIGFIGDQSVFVRGAITGVAFEGVIAALLTSIMILLFLGSWRSTVI 362 ++ + ++ P +++ + D S+ ++ ++T V + A L ++ LFL SWRSTVI Sbjct: 302 RLDALNAELSPQNIQLRIVTDSSIPIQESVTQVQTTLIEGAALAVAIVFLFLNSWRSTVI 361 Query: 363 IAVSIPLSVLGAIIMLSLIGETLNIMTLGGLALAVGILVDDATVTIENINYHLEQGKPVE 422 +++P++++G + ++ +G TLN ++L L L++GILVDDA V ENI HL GK Sbjct: 362 TGLTLPIAIIGTLTVVDFLGFTLNTLSLLALTLSIGILVDDAIVVRENITRHLHMGKSHL 421 Query: 423 QSILDGANQIVTPAFVSLLCICIVFVPMFFLTGVARFLFVPMAEAVMFAMIWSFILSRTL 482 ++ LDG +I + I VF+P+ F+ G+ F V A++ S ++ TL Sbjct: 422 RAALDGTGEIGLAVIATTATIVAVFLPVAFMDGIVGRFFYQFGVTVSAAVLISLFVAFTL 481 Query: 483 VPTMANYLLQAHVHHEGAPPKSRNPLVWFQRGFEARFERIRSGYRGLLAMALGHRTVFVS 542 P +++ + R P+ F+ FE + YR + L HR V + Sbjct: 482 DPMLSSVWYDPDAQADA----KRGPIGRLIARFDHGFEWMAGQYRHAIDWTLRHRLVTLL 537 Query: 543 CFLAVVAASFLLVPFLGRNFFPSVDAGNILMHVRTQVGTRVEETANQLADIQKAIRKLVP 602 + S +VP +G F P D G +++ VG+ ++ T +L ++KA+R+ Sbjct: 538 VTAGIFIGSLFMVPLVGTEFVPDADEGRFQINLTAPVGSSLDYTTAKLQQVKKALREF-- 595 Query: 603 GEIETMTDNIGMPISGINMTYNNTGVIGPQDGDIQIRLKEGHKPTEEHVRT-------LR 655 E+E + I N G G I + G P +T +R Sbjct: 596 PEVEMLYSTI-----------NTGGAAGKHRAAILV----GLVPLSAREQTPLSLAEPVR 640 Query: 656 EQLPRLFPGTSFAFLPADIVSQILNFGAPAPIDLQIRGANLEANFAYANKLLAGIKRIPG 715 ++L + PG L + G +P+ L I G + AN L+ +K+IPG Sbjct: 641 KRLSAI-PGIEINILQNGL------GGGESPVQLSILGDDRAVLEKIANGLVEDMKKIPG 693 Query: 716 IADARIQQSPNNPTFNIDVDRTRAQYVGLTERDVTNSLVVNLAGSSQVAPTYYLNPDNGV 775 + + ++ + A +G+ D+ +L + G +G Sbjct: 694 LVEVTSSTKDVTSILSVRLKPAAASDLGIARADLAAALSALIGGED----VSKWTDAHGN 749 Query: 776 SYSIVMQTPQYQIDSLSALQTLPITA--TGNTQAPI---LGGIADIKRATSSAVVSQYDI 830 SY IV++ P + + L L IT TG AP+ L +ADI + A + ++D Sbjct: 750 SYDIVVRLPVERRSDAARLGELMITTGRTGANGAPLMVRLDQVADIGTVAAPAEIRRFDN 809 Query: 831 QSLVQIYATTQGRDLGGVATDVRKLIADTAKEVPKGSSVVLLGQVQTMNSAFTGLLFGLL 890 + + + A GR LG V ++ L A ++++P G + G+ +TM + L Sbjct: 810 RREILVSANITGRTLGDVTETLQGLTA--SRDLPAGYRIRFGGEAETMQETVGHMGTALS 867 Query: 891 GAVVLIYFLIVVNFQSWSDPFVIITALPAALAGIVWMLFTTETTLSVPALTGAIMCMGVA 950 A++ IY ++ F S+ P I+ +LP +L G++ L +T+++ +L G IM MG+ Sbjct: 868 MAIIFIYIVLASQFGSFLQPLAIMVSLPLSLIGVLLGLMVAGSTINMFSLIGFIMLMGLV 927 Query: 951 TANSVLVISFA-RERYEELGDPVAAALEAGFVRFRPVLMTALAMIIGMAPMALGLGEGGE 1009 T N +L++ FA RER L A A AG +RFRP++MT LAMI GM P+ L +G GG Sbjct: 928 TKNGILLVDFANRERRRGLTLNEALA-NAGVIRFRPIIMTTLAMIFGMIPLGLAVGGGGA 986 Query: 1010 QNAPLGRAVIGGLIFATFATLMFVPVVFSMV 1040 Q AP+ AV+GGLI +T TL+ VPV+ S + Sbjct: 987 QRAPMAHAVVGGLISSTLLTLIVVPVILSYI 1017 >alr5294 [V] COG0841 Cation/multidrug efflux pump Nos Nostoc sp. PCC 7120 Length = 1080 Score = 322 bits (826), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 288/1062 (27%), Positives = 490/1062 (46%), Gaps = 65/1062 (6%) Query: 16 VVLAILLLIIGPLAALRTPTDIFPDIRIPVIGVVWQYTGLPPDQMSGRITTPFQRALTTT 75 ++L + ++++G ++ P D+ P I P IGV Q G+ P+ +T P + A + T Sbjct: 24 LMLTLAVIVLGVFFIVKLPVDLLPSITYPRIGVRIQAPGISPEVGVDEVTRPLEEAFSAT 83 Query: 76 VNDIEHIVANSYNGVGIIKIFFQPNVDIRTANAQVTAISQTLLKQMPPGATPPLILNYSA 135 + I + + G + ++FQP +I A TA ++P P + Sbjct: 84 -EGVVQIFSQTREGQVSLDLYFQPGGNIDQALNDATAAFNRSRGRLPDTIEEPRLFKIDP 142 Query: 136 STVPIIQVALSGEGLTEQNLADIGINQLRTPLVTVPGAAIPYPFGGKQRQVQIDLNSTAL 195 S +P+ + AL+ L +L +L L V G A GG Q +++++++ L Sbjct: 143 SQLPVYEFALTSPSLEGLDLRVFAEEELARELGVVSGVAGVDVSGGVQEEIRVNIDLDRL 202 Query: 196 QARGLSGQDVANALAAQNLITPVG----------TQKIGNFEYTINLNNSPLRLEELGDL 245 QA G+ DV + L +N+ G T+ +G F+ L N + Sbjct: 203 QALGVGLTDVLDELRDRNVDISGGRILGQNSEPLTRTVGRFQNADELRNLSFEVSSTASS 262 Query: 246 -PIKQ--VNGAMVYVRDVASVRDGNPPQTNIIHVDGNRSVLMMVLKAGATSTLDIISGIK 302 P +Q V+ VY+RD A + DG Q + ++G +V + V K +T++++ +K Sbjct: 263 NPNQQQNVSNRRVYLRDFAQIIDGAEQQRIYVSLNGEPAVKVSVQKQPDANTINVVDAVK 322 Query: 303 QKVIEVKDQ--MPDALKIGFIGDQSVFVRGAITGVAFEGVIAALLTSIMILLFLGSWRST 360 +++ E++ +P+ I D+S F+R +I+ V G+I L +I +LLFLGS R T Sbjct: 323 KRLEELRQSSIVPEGTVITPTLDESRFIRNSISNVTSSGLIGTALAAIAVLLFLGSLRQT 382 Query: 361 VIIAVSIPLSVLGAIIMLSLIGETLNIMTLGGLALAVGILVDDATVTIENI--------- 411 II V+IPL+ L AII++ L G ++N+ +LGGLAL VGI+VD++ V +ENI Sbjct: 383 FIIVVAIPLATLAAIILMGLFGLSINVFSLGGLALGVGIVVDNSIVMLENIAEGAGVTPG 442 Query: 412 ---NYHLEQGKPVEQSILDGANQIVTPAFVSLLCICIVFV-PMFFLTGVARFLFVPMAEA 467 L + + Q+ + ++Q V A ++ +V V P + G LF + Sbjct: 443 KDSKSRLSHKQLIAQA--ETSSQEVESALIASTSTNLVAVLPFLLIGGFIALLFNELILT 500 Query: 468 VMFAMIWSFILSRTLVPTMANYLLQAHVHHEGAPPKSRNPLVWFQRGFEARFERIRSGYR 527 + F++ S I++ T+VP + + LL G S W R F RFE GY Sbjct: 501 ITFSVAASIIIAVTVVPMLTSRLL-------GWKFSSGLSNFWPLRKFNERFEAATRGYS 553 Query: 528 GLLAMALGHRTVFVS-CFLAVVAASFLLVPFLGRNFFPSVDAGNILMHVRTQVGTRVEET 586 LA L R V V+ L S + P + + P + G + + GT +E Sbjct: 554 RFLAGILRWRLVTVAIAILLFGGGSLWMAPQIPQQILPRISTGQASLFAQFPPGTPLETN 613 Query: 587 ANQLADIQKAIRKLVPGEIETMTDNIGMPISGINMTYNNTGVIGPQDGDIQIRLKEGHKP 646 + ++ + + IR+ E E G + G N N P G I LK G Sbjct: 614 SKVMSAVDEIIRQ--QPETEYTFTTAGGALFGTNTNAN------PLRGTSTITLKPGTN- 664 Query: 647 TEEHVRTLREQLPRL-FPGTSFAFLPADIVSQILNFGAP---APIDLQIRGANLEANFAY 702 + +V + ++L +L G P + I N +P A +D+ ++G N + Sbjct: 665 VDTYVERVTQELNKLNLAGIRLRLAPGQVRGLITN-NSPVRNADVDVILQGTNEDTLQQA 723 Query: 703 ANKLLAGIKRIPGIADARIQQSPNNPTFNIDVDRTRAQYVGLTERDVTNSLVVNLAGSSQ 762 + ++LA ++ R P I D R +GLT RD+ +++ L GS Sbjct: 724 SRQVLAALEEQATQVRFRPDADERQPEIQILPDWERVSALGLTTRDIGDTIQTALEGS-- 781 Query: 763 VAPTYYLNPDNGVSYSIVMQTPQYQIDSLSALQTLPITATGNTQAPILGGIADIKRATSS 822 PT + V + Q + + + S L+ LP+ GN + L +A I A + Sbjct: 782 -IPTQLQRGNRLVDVRV--QLNESAVQTGSQLERLPL-FVGNNRQVRLSDVATIVEAQAP 837 Query: 823 AVVSQYDIQSLVQIYATT--QGRDLGGVATDVRKLIADTAKEVPKGSSVVLLGQVQTMNS 880 + + + Q V I+A +G L V +I++ E+P+G SV+ ++ Sbjct: 838 GEIQRIN-QRQVVIFAGNLIEGASLSRAIEQVNNVISNL--ELPEGVSVLPSAAAESNQQ 894 Query: 881 AFTGLLFGLLGAVVLIYFLIVVNFQSWSDPFVIITALPAALAGIVWMLFTTETTLSVPAL 940 + L A L++ ++ V + S DP VI+ +P ALAG ++ L+ T T + + Sbjct: 895 LQSSLQLLGGLASFLVFVVMAVQYNSLIDPLVIMFTIPLALAGGIFGLYITNTAIGATVI 954 Query: 941 TGAIMCMGVATANSVLVISFARE-RYEELGDPVAAALEAGFVRFRPVLMTALAMIIGMAP 999 GA++ +G+ N+++++ A + R + D A L+A R RP+LMT + ++GM P Sbjct: 955 VGAVLLVGIVVNNAIIMVELANQIRDRDKVDRRTAILQAAPQRLRPILMTTITTVLGMFP 1014 Query: 1000 MALGLGEGGEQNAPLGRAVIGGLIFATFATLMFVPVVFSMVH 1041 +ALG+GEG E PLG V GL AT TL +P + ++H Sbjct: 1015 LALGIGEGSEFLQPLGVVVFSGLSLATLLTLFIIPCFYILLH 1056 >AGc3721 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1048 Score = 318 bits (816), Expect = 4e-86, Method: Compositional matrix adjust. Identities = 284/1073 (26%), Positives = 506/1073 (47%), Gaps = 81/1073 (7%) Query: 2 IALVRIALSRPYTFVVLAILLLIIGPLAALRTPTDIFPDIRIPVIGVVWQYTGLPPDQMS 61 +A + + RP VL LL++ G A + PD+ P I V Y G P+ + Sbjct: 12 LAFTALFVRRPILAAVLNTLLVVAGLAALVGVEVRELPDVDRPSISVRTTYEGAAPETID 71 Query: 62 GRITTPFQRALTTTVNDIEHIVANSYNGVGIIKIFFQPNVDIRTANAQVTAISQTLLKQM 121 +T + A+ V+ I+ I ++S G + + F NVD+ A V + Q+ Sbjct: 72 QEVTQTIEGAVAR-VSGIKSIASSSQFGTSRVTMEFSDNVDMAVAANDVRDAIGRVTNQL 130 Query: 122 PPGATPPLILNYSASTVPIIQVALSGEGLTEQNLADIGINQLRTPLVTVPGAAIPYPFGG 181 P A P I+ + + PI+++A++ L+ ++L + +++ L V G A +G Sbjct: 131 PDDADEPQIIKADSDSQPIMRLAVTSSTLSMEDLTKLVDDEIIDRLAAVDGVADVELYGD 190 Query: 182 KQRQVQIDLNSTALQARGLSGQDVANALAAQNLITPVGTQKIGNFEYTINLNNSPLRLEE 241 +++ ++DLN AL +RGL+ DV+NALA+ L P G+ K + + S + E+ Sbjct: 191 QEKVFRVDLNQAALASRGLTVTDVSNALASAALDVPAGSLKSTTQDIVVRATASLTKPED 250 Query: 242 LGDLPIKQVNGAMVYVRDVASVRDGNPPQTNIIHVDGNRSVLMMVLKAGATSTLDIISGI 301 +L IK + +RDVA+V G Q+ + +G + V + V++ ++TL+I +G+ Sbjct: 251 FSNLLIKD----NIRLRDVATVMLGADDQSTSLRSNGVQGVGLGVIRQAQSNTLNISTGV 306 Query: 302 KQKVIEVKDQMPDALKIGFIGDQSVFVRGAITGVAFEGVIAALLTSIMILLFLGSWRSTV 361 K V + +P+ +I D +VF+ GA+ V ++AL+ +++ LF WR+T+ Sbjct: 307 KAAVDAMSANLPEGTRIVVTSDDAVFIEGALHEVELALGLSALIVVVVLYLFFRDWRATL 366 Query: 362 IIAVSIPLSVLGAIIMLSLIGETLNIMTLGGLALAVGILVDDATVTIENINYHLEQGKPV 421 I A+++P++++G I+ + ++G ++NI+TL + LA G++VDDA V +ENI +G Sbjct: 367 IPAITMPVALIGTIVAIYMVGFSVNILTLLAIVLATGLVVDDAIVVLENIVRRRAEGMGP 426 Query: 422 EQSILDGANQIVTPAFVSLLCICIVFVPMFFLTGVARFLFVPMAEAVMFAMIWSFILSRT 481 + + G ++ + + VF+P+ FL G LF + FA+ S I + T Sbjct: 427 RAAAVLGTQEVFFAVIATTATLAAVFIPLSFLPGQLGGLFREFGFVLAFAVGLSSITALT 486 Query: 482 LVPTMANYLLQAHVHHEGAPPKSRNPLVWFQRGFEARFERIRSGYRGLLAMALGHRTVFV 541 L P +A+ +L+ + + PL+WF F S Y+ LA L + + + Sbjct: 487 LCPMLASRMLKQGLK------EPTGPLMWFGNVFA-------STYKTTLAACLNNPLIVI 533 Query: 542 SCFLAVVAASFLLVPFLGRNFFPSVDAGNILMHVRTQVGTRVEETANQLADIQKAIRKLV 601 L S++ + P D +++M V G +E T +QL I++ ++ L Sbjct: 534 VVALIFSGLSWIAFGMIQNELTPREDRASVMMRVTAPQGVSLEYTRDQLQRIEENLQPLR 593 Query: 602 -PGEIETMTDNIGMPISGINMTYNNTGVIGPQDGDIQIRLKEGHKPTEEHVRTLREQLPR 660 GEI + I+G+N + N G + + L P + RT + Sbjct: 594 DSGEIRNV-----YSITGMNGSSNT--------GFMVLTLA----PWADRERTQNQ---- 632 Query: 661 LFPGTSFAFLPADIVSQI-----LNFGAPAPIDLQIRGA-----------NLEANFAYAN 704 + AD+ S L A P L+IRGA N A Sbjct: 633 ---------IAADVTSAANKVPALRGNAMQPNSLRIRGAGNGLQMAMVGSNYPALTEATQ 683 Query: 705 KLLAGIKRIPGIADA-RIQQSPNNPTFNIDVDRTRAQYVGLTERDVTNSLVVNLAGSSQV 763 KLL ++ G+ D R+ PN ++ +DR RA +G+ ++ S+ L G S V Sbjct: 684 KLLLSMEE-GGLFDTPRLDNEPNQAQLSVSIDRERASDLGIDITGLSRSMQSLLEGRSIV 742 Query: 764 APTYYLNPDNGVSYSIVMQTPQYQIDSLSALQTLPITATGNTQAPILGGIADIKRATSSA 823 +++ D + + + + I+ + L+ + TG+ + + IA +K +A Sbjct: 743 --DVFVDGD---AIPVRLLSSTRPINDPTDLENV-FLKTGDGKIVPMSVIATLKE---NA 793 Query: 824 VVSQYDI-QSLVQIYATTQGRDLGGVATDVRKLIADTAKEVPKGSSVVLLGQVQTMNSAF 882 V Q + Q L + T +D + + K+ +P G+ ++ LG+ T+ Sbjct: 794 VAPQLNREQQLPSVGFTANLKDGVSLGQAMEKVNELAQSVMPSGARLLPLGEAATLEENS 853 Query: 883 TGLLFGLLGAVVLIYFLIVVNFQSWSDPFVIITALPAALAGIVWMLFTTETTLSVPALTG 942 +G+L A+ +I+ ++ F+S +I++ +P LA V L T ++L+V + G Sbjct: 854 SGMLLTFGFAIAIIFLVLAAQFESVLSSVIIMSTVPLGLACAVIALLVTGSSLNVYSQIG 913 Query: 943 AIMCMGVATANSVLVISFARERYEELGDPVAAALE-AGFVRFRPVLMTALAMIIGMAPMA 1001 ++ +GV N +L++ FA ++ G V A+E A +R RPV+MT +A I+G P+ Sbjct: 914 LVLLVGVMAKNGILIVEFANHLRDQ-GATVREAIEKATSIRLRPVMMTMIATILGGVPLV 972 Query: 1002 LGLGEGGEQNAPLGRAVIGGLIFATFATLMFVPVVFSMVHKKQGAKAAASSEI 1054 L G G E LG ++GGL FAT TL PV + ++ + AK A EI Sbjct: 973 LAQGAGAEARIALGWVIVGGLGFATLVTLYITPVSYLLIARF--AKPQADEEI 1023