BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0200.0086.p (406 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1445 [GEPR] COG0477 Permeases of the major facilitator superf... 424 e-118 all7627 [GEPR] COG0477 Permeases of the major facilitator superf... 370 e-102 PAB0874 [GEPR] COG0477 Permeases of the major facilitator superf... 182 8e-46 MJ1317 [GEPR] COG0477 Permeases of the major facilitator superfa... 179 1e-44 PH0718 [GEPR] COG0477 Permeases of the major facilitator superfa... 164 3e-40 >RSc1445 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 400 Score = 424 bits (1089), Expect = e-118, Method: Compositional matrix adjust. Identities = 240/398 (60%), Positives = 299/398 (75%), Gaps = 4/398 (1%) Query: 7 SPSPPA--RIPTGIWALGFVSMLMDISSEMIHALLPVYLVTVLGTSMVTVGFIEGIAEAT 64 +P P R+P GIW LG VS+LMD++SEMIH+LLP+++V+ LG S +TVG +EG+AE+T Sbjct: 4 NPRPDVLRRLPPGIWVLGGVSLLMDVASEMIHSLLPMFMVSALGASALTVGLVEGLAEST 63 Query: 65 ASITKIFSGALSDWLGKRKLLAAIGYGIAAFTKPVFPLAPTVDWLIAARFIDRVGKGIRG 124 A I KIFSGALSD+LG+RK LA GY + A +KP+F LAPT ++AAR +DRVGKG+RG Sbjct: 64 ALIVKIFSGALSDYLGRRKGLAVFGYALGAVSKPLFALAPTAGLVLAARLLDRVGKGVRG 123 Query: 125 APRDALVADIAPAELRGASFGLRQSLDTVGAFVGPLLAIALMWVSADNFHAVFWLAVVPA 184 APRDALVADIAP ELRGA+FGLRQSLDTVGAF+GPLLA+ LM A++F AVFW+AVVP Sbjct: 124 APRDALVADIAPPELRGAAFGLRQSLDTVGAFLGPLLAVGLMLRWANDFRAVFWVAVVPG 183 Query: 185 FLSLAVIVVAVEEPRRHADDGGTKNPLSLAAAKQLGESYWRVVGIGVVFTLARFSEAFLI 244 LS+A++ + EP A NP+ A ++L +YW VV IG VFTLARFSEAFL+ Sbjct: 184 LLSVALLAFGLREPAARAAT-HRANPIRRANLRRLTRAYWWVVAIGAVFTLARFSEAFLV 242 Query: 245 LRAQNVGLGAMWIPAVLVLMNIVYALSAYPAGVLSDRINRTGLLALGLVCLAAADLALAT 304 LRAQ G+ +P V+V MN+VYALSAYP G LSDR++ TGLLALGLV L AADL L Sbjct: 243 LRAQRGGVPIALVPLVMVAMNVVYALSAYPFGKLSDRVSHTGLLALGLVVLIAADLVLGA 302 Query: 305 LANLGGLALGVILWGLHMGLTQGLFATLIADASPASLRGTAYGYFNLSTGVAMLGSSVIA 364 + G + GV LWG+HMG+TQGL AT++AD +PA LRGTAYG FNL +G+AML +S +A Sbjct: 303 TDHWGAVLAGVALWGVHMGITQGLLATMVADTAPADLRGTAYGAFNLVSGIAMLVASALA 362 Query: 365 GALWDAFGPAATFLSGLAFTLLSLAGLLAIDTSGKGAN 402 G LWDA G AATF +G F L+LA LLAI + A+ Sbjct: 363 GWLWDAHGAAATFHAGAVFCGLALA-LLAIGRPWQAAS 399 >all7627 [GEPR] COG0477 Permeases of the major facilitator superfamily Nos Nostoc sp. PCC 7120 Length = 399 Score = 370 bits (949), Expect = e-102, Method: Compositional matrix adjust. Identities = 199/393 (50%), Positives = 273/393 (69%), Gaps = 3/393 (0%) Query: 14 IPTGIWALGFVSMLMDISSEMIHALLPVYLVTVLGTSMVTVGFIEGIAEATASITKIFSG 73 IP +W LGFVS+L DISSEMIH++LP++LV+ LG +++TVG+IEGIAE+TAS+ K+FSG Sbjct: 9 IPRNVWVLGFVSLLTDISSEMIHSVLPLFLVSALGANLLTVGWIEGIAESTASVLKVFSG 68 Query: 74 ALSDWLGKRKLLAAIGYGIAAFTKPVFPLAPTVDWLIAARFIDRVGKGIRGAPRDALVAD 133 ALSD+LG+RK LA +GYG++ KP+F LA + W++ ARF DRVGKGIR APRDA+VAD Sbjct: 69 ALSDYLGQRKKLAVVGYGLSTLVKPLFALATSPAWVLMARFGDRVGKGIRVAPRDAIVAD 128 Query: 134 IAPAELRGASFGLRQSLDTVGAFVGPLLAIALMWVSADNFHAVFWLAVVPAFLSLAVIVV 193 + + RGA++GLRQSLDT+GAF GPL+A LM S NF VFWLAV+P L++A++ Sbjct: 129 VTDSVNRGAAYGLRQSLDTIGAFTGPLVAFILMSFSGQNFRLVFWLAVLPGILAVALLAT 188 Query: 194 AVEEPRRHADDGGTKNPLSLAAAKQLGESYWRVVGIGVVFTLARFSEAFLILRAQNVGLG 253 V EP + NPL +A + LG+SYW +V + ++F L S+AFL+L+AQ G+ Sbjct: 189 GVREPDNRNNR-RQNNPLHWSALQSLGKSYWVLVVVALLFNLGNSSDAFLLLQAQQAGVS 247 Query: 254 AMWIPAVLVLMNIVYALSAYPAGVLSDRINRTGLLALGLVCLAAADLALATLANLGGLAL 313 A +P LV+MNI Y+LSAYP G+LSDRI R GLL G A A L A N Sbjct: 248 ASLVPLTLVVMNIAYSLSAYPVGLLSDRIGRLGLLVGGFCVYALAYLGFA-FVNAPWQVW 306 Query: 314 GVI-LWGLHMGLTQGLFATLIADASPASLRGTAYGYFNLSTGVAMLGSSVIAGALWDAFG 372 G+ L+GL+ G++QG+ L+AD P+ LRGTA+G NL+TGVA+L +S++ G LW Sbjct: 307 GLFGLYGLYQGMSQGILLALVADRVPSHLRGTAFGLINLATGVALLPASLLGGVLWQTIS 366 Query: 373 PAATFLSGLAFTLLSLAGLLAIDTSGKGANDRD 405 P ATF++G F L ++A LL + + + ++ Sbjct: 367 PKATFITGSIFALSAIALLLVFEGGRRKSVGKE 399 >PAB0874 [GEPR] COG0477 Permeases of the major facilitator superfamily Pab Pyrococcus abyssi Length = 392 Score = 182 bits (463), Expect = 8e-46, Method: Compositional matrix adjust. Identities = 121/373 (32%), Positives = 195/373 (52%), Gaps = 17/373 (4%) Query: 14 IPTGIWALGFVSMLMDISSEMIHALLPVYLVTVLGTSMVTVGFIEGIAEATASITKIFSG 73 I ++ LG VS L D+SSEMI ++P YL +L + G I G+ E+ +S+ K+ G Sbjct: 9 ISWNVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFG 68 Query: 74 ALSDWLGKRKLLAAIGYGIAAFTKPVFPLAPTVDW--LIAARFIDRVGKGIRGAPRDALV 131 +SD KRK A+GY I+ +K LA T W + R +DR+GKGIR APRDAL+ Sbjct: 69 YISDKFRKRKAFVALGYLISTISKG--ALAVTHSWWDFLILRILDRIGKGIRTAPRDALI 126 Query: 132 ADIAPAELRGASFGLRQSLDTVGAFVGPLLAIALMWVSADN-----FHAVFWLAVVPAFL 186 A+ + G SFG + +DT+GA GPL+A+ L+ + A+ + +F ++ VP + Sbjct: 127 AESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLISAVPGVI 186 Query: 187 SLAVIVVAVEEPRRHADDGGTKNPLSLAAAKQLGESYWRVVGIGV-VFTLARFSEAFLIL 245 + ++++ V+ D G++ + L S R+ + V + L R+S AF + Sbjct: 187 GVLIVLLLVK-------DKGSEVKKKIKGISALKSSNLRIFLVIVAIAALGRYSYAFTLW 239 Query: 246 RAQNVGLGAMWIPAVLVLMNIVYALSAYPAGVLSDRINRTGLLALGLVCLAAADLALATL 305 +A+ +G L N++YALSAYP G SD++ + ++ +G A L A Sbjct: 240 KAEELGYSVFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLASLIFAYA 299 Query: 306 ANLGGLALGVILWGLHMGLTQGLFATLIADASPASLRGTAYGYFNLSTGVAMLGSSVIAG 365 NL L L +L+GL+M + + +AD + +GT G ++ GV + +S+I G Sbjct: 300 NNLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFPASIIVG 359 Query: 366 ALWDAFGPAATFL 378 LW + FL Sbjct: 360 YLWQTYSLTVGFL 372 >MJ1317 [GEPR] COG0477 Permeases of the major facilitator superfamily Mja Methanococcus jannaschii Length = 398 Score = 179 bits (453), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 129/397 (32%), Positives = 204/397 (51%), Gaps = 23/397 (5%) Query: 3 AEPN---SPSPPARIPTGIWALGFVSMLMDISSEMIHALLPVYLVTVLGTSMVTVGFIEG 59 AE N + + ++ LGF S L D+SSEMI +LP+ L+T +G +++G + G Sbjct: 6 AEQNLQKNNENDRELSKNVYLLGFTSFLNDMSSEMIMPILPM-LITSVGGGSLSIGLVGG 64 Query: 60 IAEATASITKIFSGALSDWLGKRKLLAAIGYGIAAFTKPVFPLAPTVDWLIAARF--IDR 117 + E ++I + G SD + KRK+ +GY ++ K + L+ + WL A F ++R Sbjct: 65 LREFISNILMVLIGYCSDKVRKRKIFVVLGYLTSSMFKLLLGLSKS--WLGAVIFSSLER 122 Query: 118 VGKGIRGAPRDALVADIAPAELRGASFGLRQSLDTVGAFVGPLLAIALMWVSADNFHAVF 177 +GKGIR APRDA++++ P L G FG++++ DT GA +G L++ + +F+ + Sbjct: 123 MGKGIRTAPRDAIISESMPKTL-GKGFGIQRAFDTAGAILGSTLSLLFILYLQYSFNQII 181 Query: 178 WLAVVPAFLSLAVIVVAVEEPRRHADDGGTKNPLSLAAA-KQLGESYWRVVGIGVVFTLA 236 +A V FL+L + E+P + N ++ K L + + I +FTL+ Sbjct: 182 LIAAVIGFLTLIPLYFVKEKP------SPSNNKITFRVGIKNLPKELKLFILISAIFTLS 235 Query: 237 RFSEAFLILRAQNVGL-----GAMWIP-AVLVLMNIVYALSAYPAGVLSDRINRTGLLAL 290 FS F ILRAQ + A+ IP A+ +L NI YA + P G+LSD+I R +L + Sbjct: 236 NFSYMFYILRAQEFLMIVDEKMAIIIPIALYILYNIFYATFSIPFGILSDKIGRKSVLTI 295 Query: 291 GLVCLAAADLALATLANLGGLALGVILWGLHMGLTQGLFATLIADASPASLRGTAYGYFN 350 G + L A + L L L+G+ L G ++D S +R TA G F Sbjct: 296 GYIVYGIVSLGFAYFISQKSLILLFALYGIAYALFAGNQKAYVSDLSSEDIRATALGLFY 355 Query: 351 LSTGVAMLGSSVIAGALWDAFGPAATFLSGLAFTLLS 387 G+ L +S+IAG LW P TFL G ++S Sbjct: 356 TVVGLTSLPASLIAGYLWKI-SPEMTFLYGSVLAIIS 391 >PH0718 [GEPR] COG0477 Permeases of the major facilitator superfamily Pho Pyrococcus horikoshii Length = 398 Score = 164 bits (416), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 114/375 (30%), Positives = 189/375 (50%), Gaps = 17/375 (4%) Query: 12 ARIPTGIWALGFVSMLMDISSEMIHALLPVYLVTVLGTSMVTVGFIEGIAEATASITKIF 71 A I ++ LG VS L D+SSEMI ++P YL +L + G I G+ E+ +S+ K+ Sbjct: 11 AGISWNVFLLGLVSFLNDMSSEMIAPIVPTYLTDILKMGKLASGSIMGLIESLSSLFKVI 70 Query: 72 SGALSDWLGKRKLLAAIGYGIAAFTKPVFPLAPTVDW--LIAARFIDRVGKGIRGAPRDA 129 G +SD KRK A+GY ++ K LA T W + R +DR+GKGIR APRDA Sbjct: 71 FGYISDVFRKRKTFVALGYLLSTIAKG--ALALTHSWWDFLTLRILDRIGKGIRTAPRDA 128 Query: 130 LVADIAPAELRGASFGLRQSLDTVGAFVGPLLAIALMWVSADN-----FHAVFWLAVVPA 184 L+A+ + G SFG + +DT+GA GPL+A+ L+ + + + +F ++ +P Sbjct: 129 LIAESSEKGKSGKSFGFHRMMDTLGAVTGPLVAVGLLALLSKYPKELAYRYIFLISAIPG 188 Query: 185 FLSLAVIVVAVEEPRRHADDGGTKNPLSLAAAKQLGESYWR-VVGIGVVFTLARFSEAFL 243 + + +++ V+ D GG + L + R + + + L R+S AF Sbjct: 189 AIGVLIVIFLVK------DRGGIVKK-KIKEISSLKSPHLRAFLAVVAIAALGRYSYAFT 241 Query: 244 ILRAQNVGLGAMWIPAVLVLMNIVYALSAYPAGVLSDRINRTGLLALGLVCLAAADLALA 303 + + + +G L N++YAL+AYP G SD++ + ++ G A L A Sbjct: 242 LWKVKELGYSIFQGLEFYALFNVIYALAAYPIGSYSDKVGKKKIITTGFGIAGLASLLFA 301 Query: 304 TLANLGGLALGVILWGLHMGLTQGLFATLIADASPASLRGTAYGYFNLSTGVAMLGSSVI 363 +L L L IL+G++M + + +AD + +GT G ++ G+ + +S+I Sbjct: 302 YSKSLAMLMLAFILYGVYMAIEDTIPRAYMADLAKEYEKGTIIGMYHTVFGIFVFPASII 361 Query: 364 AGALWDAFGPAATFL 378 G LW + FL Sbjct: 362 VGYLWQTYSLEIGFL 376