BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0200.0050.p (546 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC1799 Non COG 408 e-113 CC1818 Non COG 394 e-109 Rv1393c [P] COG2072 Predicted flavoprotein involved in K+ transp... 207 4e-53 MT1438 [P] COG2072 Predicted flavoprotein involved in K+ transpo... 207 4e-53 PA2097 [P] COG2072 Predicted flavoprotein involved in K+ transpo... 204 4e-52 >CC1799 Non COG Length = 556 Score = 408 bits (1049), Expect = e-113, Method: Compositional matrix adjust. Identities = 212/541 (39%), Positives = 302/541 (55%), Gaps = 5/541 (0%) Query: 5 VTRSNGSNGAHATTKLDAVVVGAGVAGLYQLFRLREQGLSVKAIDAGSSVGGTWYWNRYP 64 +T S + T++DA+V+GAG G+Y + +L GLSV+ +AG VGG WYWNRYP Sbjct: 1 MTASQQPTASQDPTRIDALVIGAGFGGMYAVHKLSGMGLSVQGFEAGGDVGGVWYWNRYP 60 Query: 65 GARFDSEGHTYQYLFSEELYKGWSWSERFPGQPEIERWLNYVADRLDLRKDIKFGTTVKS 124 GAR D Y Y FS ++ + W+WSE+F Q EI + N+VADRLDLR+ F T V Sbjct: 61 GARCDLMSLDYCYSFSPDIEQEWTWSEQFAAQSEILAYANFVADRLDLRRHFLFETWVTG 120 Query: 125 AHFNEATQRWLVATDQGDVIDTQFLVTCCGMLSAPH-VSFPGQETFNGKLFHTARWPKGP 183 A ++EA W V D G V + + V G LS P V F G + F G++ A+WP P Sbjct: 121 AAYDEAANVWRVTVDDGRVFEATYCVMASGPLSIPKGVPFDGADDFKGEILLAAKWPHTP 180 Query: 184 IELAGKRVGVVGNGATGIQVIQSIAGEVGHLKVFIRTPQYIIPMKNPKWDASDAEAYKSK 243 + GKRVG+VG G+TGIQ++ +A G L VF RTP + +PM+N + K Sbjct: 181 VSFEGKRVGLVGTGSTGIQIVPEVAKTAGALTVFQRTPSFTLPMRNVTLEPDYVAELKRN 240 Query: 244 FKFLTERLPKT-FTGFEFDFEHAWADLTPQQRRQVIEDCWNDGSLKLWVSSFAELFFDEA 302 + + + + G + +TP+QRR ++ED W G L ++ +F++L + Sbjct: 241 YAGIRQVARNSPLGGVRPQSTRPFFSVTPEQRRALMEDSWARGGLS-FLGTFSDLLVNPE 299 Query: 303 VNAEITEFVREKMRERIKDPKLCELLIPADYGFGTHRVPLESNFLEAFHRPNVEIVSVKN 362 N ++ EFVR K+ E + DP E L P Y R L++++ E F+ P+V++ Sbjct: 300 ANEQVAEFVRSKISEVVTDPVTAEKLKPRGYPIFARRPCLDTHYYETFNLPHVKLHDCLE 359 Query: 363 NPIARITPEGIQTADGTVHEFDVIILATGFDAGTGALTRIDIRGRDGRSLKDDWGRDIRT 422 +PI +ITP G+ T G V E DV+I ATG+D TGAL D+ GR G L+D W ++ Sbjct: 360 SPIVKITPAGLLTETGEV-ELDVLIFATGYDGLTGALLNFDVVGRGGLQLRDKWRDGAKS 418 Query: 423 TMGLQVHGYPNLFTTAVPLAPSAALCNMTTCLQQQVEWIADCIGYLRGKNLNVIEPTRDT 482 +GL + +PNLF P P AAL N+ T QQ ++WIAD I ++R + L IEPT Sbjct: 419 HLGLMIASFPNLFLVCGPNGP-AALANIITLDQQNIDWIADAITHMRQEGLATIEPTEGA 477 Query: 483 EDQWVAHHDETANATLIAKTNSWYLGSNVEGKPRRVLSYCGGVGTYRQKCDEVAASGYRG 542 E W+ A TL++K N+WY+G N+ GKPR + Y GG Y + C A GY Sbjct: 478 EQGWMDMVYGMAELTLVSKANTWYVGGNISGKPRGLSMYTGGFQRYSEACRLAAEKGYED 537 Query: 543 F 543 F Sbjct: 538 F 538 >CC1818 Non COG Length = 543 Score = 394 bits (1011), Expect = e-109, Method: Compositional matrix adjust. Identities = 206/540 (38%), Positives = 307/540 (56%), Gaps = 7/540 (1%) Query: 5 VTRSNGSNGAHATTKLDAVVVGAGVAGLYQLFRLREQGLSVKAIDAGSSVGGTWYWNRYP 64 + S G GA + A+VVGAG G+Y + RLR++GLSV ++AG VGGTWYWNRYP Sbjct: 3 INTSAGPTGA--VRRAQAIVVGAGFGGMYAIHRLRQEGLSVLGLEAGGDVGGTWYWNRYP 60 Query: 65 GARFDSEGHTYQYLFSEELYKGWSWSERFPGQPEIERWLNYVADRLDLRKDIKFGTTVKS 124 GAR D Y Y FS+ + + W+WSE F EI + N+VADRLDLR +F T V++ Sbjct: 61 GARCDVTSIDYSYAFSQAIEQEWTWSEVFAAGSEILAYANFVADRLDLRSAYQFNTRVQT 120 Query: 125 AHFNEATQRWLVATDQGDVIDTQFLVTCCGMLSAPH-VSFPGQETFNGKLFHTARWPKGP 183 F++A + W + TDQG + L+ G LS P V PG + F G+L+ + +WP Sbjct: 121 IAFDDARRVWTLTTDQGQRFEADNLIMATGPLSLPKPVDIPGADRFKGELYRSGKWPHHA 180 Query: 184 IELAGKRVGVVGNGATGIQVIQSIAGEVGHLKVFIRTPQYIIPMKNPKWDASDAEAYKSK 243 ++ +GKRVGVVG G++GIQ++ +A L VF RTP + +PM+N K A K+ Sbjct: 181 VDFSGKRVGVVGTGSSGIQIVPVVAETCQSLTVFQRTPSFTLPMRNKKVSEDYAAQLKAN 240 Query: 244 FKFLTERLPKTFTGFEFDFE-HAWADLTPQQRRQVIEDCWNDGSLKLWVSSFAELFFDEA 302 L TFTG + ++R +++E+ W G+L+ ++ F++L + A Sbjct: 241 MAGLRAAARTTFTGGVRPLSTRPLFSIPVEERNELMEEAWAKGALQ-FLGLFSDLLTNAA 299 Query: 303 VNAEITEFVREKMRERIKDPKLCELLIPADYGFGTHRVPLESNFLEAFHRPNVEIVSVKN 362 N + +FVR+K+ + +KDP E L P Y R L++ + E ++ P+V +V Sbjct: 300 ANEIVADFVRDKISQTVKDPVTAEALKPRGYPIYARRPCLDTQYYETYNLPHVSLVDCFE 359 Query: 363 NPIARITPEGIQTADGTVHEFDVIILATGFDAGTGALTRIDIRGRDGRSLKDDWGRDIRT 422 PI+ T G++T+ + DVII+ATG+DA TG + IDI GRDG L + W R+ Sbjct: 360 EPISAFTETGLRTSQREI-ALDVIIMATGYDALTGPMLAIDITGRDGLKLSEAWRDGPRS 418 Query: 423 TMGLQVHGYPNLFTTAVPLAPSAALCNMTTCLQQQVEWIADCIGYLRGKNLNVIEPTRDT 482 + L +HG+PNLF P PS L N + V+W+ DCI +++ + L +E T + Sbjct: 419 YLALLMHGFPNLFIIGGPNGPS-ILANYIRLDELNVDWVVDCILHMQREGLATVEATAEA 477 Query: 483 EDQWVAHHDETANATLIAKTNSWYLGSNVEGKPRRVLSYCGGVGTYRQKCDEVAASGYRG 542 + +W E A+ TL K ++WY G+N+EGKPR + GG+ Y + C VAA+GY G Sbjct: 478 QTRWSQTVGEIADRTLYVKADTWYTGTNIEGKPRGFFVFAGGLNRYAEICAGVAAAGYEG 537 >Rv1393c [P] COG2072 Predicted flavoprotein involved in K+ transport Mtu Mycobacterium tuberculosis H37Rv Length = 492 Score = 207 bits (528), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 149/500 (29%), Positives = 228/500 (45%), Gaps = 54/500 (10%) Query: 22 AVVVGAGVAGLYQLFRLREQGLS-VKAIDAGSSVGGTWYWNRYPGARFDSEGHTYQYLFS 80 A++VGAG +G+ +L G S ++AG VGGTW+WN YPG D +YQ+ F Sbjct: 7 ALIVGAGFSGIGAAIKLDRAGFSDYLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFE 66 Query: 81 EELYKGWSWSERFPGQPEIERWLNYVADRLDLRKDIKFGTTVKSAHFNEATQRWLVATDQ 140 + + WS + E++ + + D+ +R I+ T V +A F++ W V TD Sbjct: 67 QSRH----WSRTYAPGHELKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDP 122 Query: 141 GDVIDTQFLVTCCGMLSAPHV-SFPGQETFNGKLFHTARWPKGPIELAGKRVGVVGNGAT 199 G I +FL++ CG+L+ P + G ++F G HTARW +L GKRVG++G GA+ Sbjct: 123 GGEITARFLISACGILTVPKLPDIDGVDSFEGVTMHTARWDHTQ-DLTGKRVGIIGTGAS 181 Query: 200 GIQVIQSIAGEVGHLKVFIRTPQYIIPMKNPKWDASDAEAYKSKFKFLTERLPKTFTGFE 259 +QVI +A V HL VF RTP + PK+D A + Sbjct: 182 AVQVIPEMAPIVSHLTVFQRTPIWCF----PKFDVPLPTAVR------------------ 219 Query: 260 FDFEHAWADLTP--QQRRQVIEDCWNDGSLKLWVSSFAELFFDEAVNAEITEFVREKMRE 317 WA P + +++ + + + + FA F A + E R +R+ Sbjct: 220 ------WAMRIPGGKAVHRLLSQAFVEATFPIAAHYFA--VFPLAKHMESAG--RRYLRQ 269 Query: 318 RIKDPKLCELLIPADYGFGTHRVPLESNFLEAFHRPNVEIVSVKNNPIARITPEGIQTAD 377 ++ DP + E L P Y G R + +L F+R NV +V+ PI +ITP + T D Sbjct: 270 QVHDPVVREQLTP-RYAVGCKRPGFHNTYLSTFNRDNVRLVT---EPIDKITPTAVATTD 325 Query: 378 GTVHEFDVIILATGFDA-GTGALTRIDIRGRDGRSLKDDWGRD-IRTTMGLQVHGYPNLF 435 G HE DV++LATGF T ++ + G G SL W ++ G+ V GYPN F Sbjct: 326 GASHEIDVLVLATGFKVLDTDSIPTYAVTGTGGASLSRFWDEHRLQAYEGVSVPGYPNFF 385 Query: 436 TTAVPLAPSAALCNMTTCLQQQVEWIADCIGYLRGKNLNVIEPTRDTEDQWVA-----HH 490 T P + + ++ Q I C+ R IE T + ++ A H Sbjct: 386 TVFGPYGYVGS--SYFALIETQAHHIIRCLKRARRTGATRIEVTEEANARYFAEVMRRRH 443 Query: 491 DETANATLIAKTNSWYLGSN 510 + NS+Y N Sbjct: 444 RQVFWQDSCRLANSYYFDKN 463 >MT1438 [P] COG2072 Predicted flavoprotein involved in K+ transport MtC Mycobacterium tuberculosis CDC1551 Length = 492 Score = 207 bits (528), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 149/500 (29%), Positives = 228/500 (45%), Gaps = 54/500 (10%) Query: 22 AVVVGAGVAGLYQLFRLREQGLS-VKAIDAGSSVGGTWYWNRYPGARFDSEGHTYQYLFS 80 A++VGAG +G+ +L G S ++AG VGGTW+WN YPG D +YQ+ F Sbjct: 7 ALIVGAGFSGIGAAIKLDRAGFSDYLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFE 66 Query: 81 EELYKGWSWSERFPGQPEIERWLNYVADRLDLRKDIKFGTTVKSAHFNEATQRWLVATDQ 140 + + WS + E++ + + D+ +R I+ T V +A F++ W V TD Sbjct: 67 QSRH----WSRTYAPGHELKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDP 122 Query: 141 GDVIDTQFLVTCCGMLSAPHV-SFPGQETFNGKLFHTARWPKGPIELAGKRVGVVGNGAT 199 G I +FL++ CG+L+ P + G ++F G HTARW +L GKRVG++G GA+ Sbjct: 123 GGEITARFLISACGILTVPKLPDIDGVDSFEGVTMHTARWDHTQ-DLTGKRVGIIGTGAS 181 Query: 200 GIQVIQSIAGEVGHLKVFIRTPQYIIPMKNPKWDASDAEAYKSKFKFLTERLPKTFTGFE 259 +QVI +A V HL VF RTP + PK+D A + Sbjct: 182 AVQVIPEMAPIVSHLTVFQRTPIWCF----PKFDVPLPTAVR------------------ 219 Query: 260 FDFEHAWADLTP--QQRRQVIEDCWNDGSLKLWVSSFAELFFDEAVNAEITEFVREKMRE 317 WA P + +++ + + + + FA F A + E R +R+ Sbjct: 220 ------WAMRIPGGKAVHRLLSQAFVEATFPIAAHYFA--VFPLAKHMESAG--RRYLRQ 269 Query: 318 RIKDPKLCELLIPADYGFGTHRVPLESNFLEAFHRPNVEIVSVKNNPIARITPEGIQTAD 377 ++ DP + E L P Y G R + +L F+R NV +V+ PI +ITP + T D Sbjct: 270 QVHDPVVREQLTP-RYAVGCKRPGFHNTYLSTFNRDNVRLVT---EPIDKITPTAVATTD 325 Query: 378 GTVHEFDVIILATGFDA-GTGALTRIDIRGRDGRSLKDDWGRD-IRTTMGLQVHGYPNLF 435 G HE DV++LATGF T ++ + G G SL W ++ G+ V GYPN F Sbjct: 326 GASHEIDVLVLATGFKVLDTDSIPTYAVTGTGGASLSRFWDEHRLQAYEGVSVPGYPNFF 385 Query: 436 TTAVPLAPSAALCNMTTCLQQQVEWIADCIGYLRGKNLNVIEPTRDTEDQWVA-----HH 490 T P + + ++ Q I C+ R IE T + ++ A H Sbjct: 386 TVFGPYGYVGS--SYFALIETQAHHIIRCLKRARRTGATRIEVTEEANARYFAEVMRRRH 443 Query: 491 DETANATLIAKTNSWYLGSN 510 + NS+Y N Sbjct: 444 RQVFWQDSCRLANSYYFDKN 463 >PA2097 [P] COG2072 Predicted flavoprotein involved in K+ transport Pae Pseudomonas aeruginosa Length = 491 Score = 204 bits (519), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 151/498 (30%), Positives = 226/498 (45%), Gaps = 46/498 (9%) Query: 12 NGAHATTKLDAVVVGAGVAGLYQLFRLREQGLS-VKAIDAGSSVGGTWYWNRYPGARFDS 70 N + L +VVGAG AGL RLR+ G+ ++ + VGG W NRYPGA D Sbjct: 3 NESRPEAPLRVLVVGAGFAGLGLAIRLRQAGIDDYLVLEKAADVGGCWRENRYPGAACDV 62 Query: 71 EGHTYQYLFSEELYKGWSWSERFPGQPEIERWLNYVADRLDLRKDIKFGTTVKSAHFNEA 130 H Y + F + WS +F Q EI +L + AD+ LR+ I+F V+ A F+ Sbjct: 63 PSHLYSFSFEPKA----DWSRKFAPQAEILDYLRHCADKYRLREKIRFHCEVEEARFDAG 118 Query: 131 TQRWLVATDQGDVIDTQFLVTCCGMLSAPHV-SFPGQETFNGKLFHTARWPKGPIELAGK 189 + W V G + + LV G LS P + PG E F G FH+A W +ELAGK Sbjct: 119 SGEWQVRCADGQTLRARALVCATGQLSRPLLPRLPGLERFQGPAFHSANW-DAEVELAGK 177 Query: 190 RVGVVGNGATGIQVIQSIAGEVGHLKVFIRTPQYIIPMKNPKWDASDAEAYKSKFKFLTE 249 RV V+G GA+ IQ + IA +V L +F R+ Y+I + Sbjct: 178 RVAVIGTGASAIQFVPRIAPQVQRLSLFQRSAPYVIAKPD-------------------- 217 Query: 250 RLPKTFTGFEFDFEHAWADLTPQQRRQVIEDCWNDGSLKLWVSSFAELFFDEAVNAEITE 309 +T+ +E + W L QR + S L ++F L + Sbjct: 218 ---RTYADWERRLKARWPWL---QRLDRGLKYLHHESRMLAFATFPAL-----MKVMRLS 266 Query: 310 FVREKMRERIKDPKLCELLIPADYGFGTHRVPLESNFLEAFHRPNVEIVSVKNNPIARIT 369 F R R+ I DP+L L+P DY G R+ + +++ A R NVE+V + I +T Sbjct: 267 FHRHLHRQ-IADPQLRARLVP-DYPLGCKRILISNDYYPALARSNVELV---DTGIREVT 321 Query: 370 PEGIQTADGTVHEFDVIILATGFDAGTGALTRIDIRGRDGRSLKDDWGRDIRTTMGLQVH 429 + + DG HE D II TGF A T L + I G DGR L+ W G+ V Sbjct: 322 EDAVVGRDGRRHEVDAIIFGTGF-AATEFLAPMRILGLDGRDLRQAWADGAEAYKGISVS 380 Query: 430 GYPNLFTTAVPLAPSAALCNMTTCLQQQVEWIADCIGYLRGKNLNVIEPTRDTEDQWVAH 489 G+PNLF P + ++ L+ Q ++ C+ L+ + L ++ + + ++ Sbjct: 381 GFPNLFILYGP-NTNLGHNSIVYMLESQFPYVLGCLRQLQEQGLRYLDVKPEVQRRFNLE 439 Query: 490 HDETANATLIAK-TNSWY 506 + T+ + +SWY Sbjct: 440 VQQGLRHTVWERGCDSWY 457