BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0200.0021.p (177 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value L179660 [R] COG4221 Short-chain alcohol dehydrogenase of unknown... 141 7e-34 AGc1567 [R] COG4221 Short-chain alcohol dehydrogenase of unknown... 137 1e-32 lin0452 [R] COG4221 Short-chain alcohol dehydrogenase of unknown... 136 3e-32 slr0315 [R] COG4221 Short-chain alcohol dehydrogenase of unknown... 135 3e-32 Z0343 [R] COG4221 Short-chain alcohol dehydrogenase of unknown s... 132 5e-31 >L179660 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity Lla Lactococcus lactis Length = 250 Score = 141 bits (356), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 78/178 (43%), Positives = 113/178 (63%), Gaps = 5/178 (2%) Query: 2 KALVEHVVRDYGALDALINCAGIMFVRPLSEINTEEWETTIDLNVKGALWAIAASLPLFL 61 K LV++ ++G +DA+ AGIM PLS ++ EEWE +D+N+KG L +AA LP F Sbjct: 72 KKLVQYAKENFGKIDAIFLNAGIMPSSPLSALHVEEWENMVDINLKGVLNGLAAVLPEFT 131 Query: 62 EQQRGHIINLSSVHGLKVFSPGGAVHSASKFALRALCEGVRAELAN--TPIRSSLITPGA 119 Q+ GH+I SSV GLK + P G V+ A+K+A+R L E +R E A T IR++ I P A Sbjct: 132 AQKSGHVITTSSVAGLKAY-PNGGVYGATKWAVRELMEVLRMESAQEGTHIRTATIYPAA 190 Query: 120 VDTGMQYKTTGSDSAR-MLAIYKN-AIPAEAVARAITFAMEQPPNVDVNEIVIRPTAQ 175 ++T + T D+A M A+Y+ I EA+AR + FA+EQP +V+V+E + PT Q Sbjct: 191 INTELLNTITDKDAAEGMTALYEQYGISPEAIARIVAFALEQPEDVNVSEFTVGPTTQ 248 >AGc1567 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 271 Score = 137 bits (345), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 72/175 (41%), Positives = 114/175 (65%), Gaps = 4/175 (2%) Query: 1 VKALVEHVVRDYGALDALINCAGIMFVRPLSEINTEEWETTIDLNVKGALWAIAASLPLF 60 V+A E + G +D ++N AGIM + +S + +EW+ I++N+KG L+ +AA LP Sbjct: 99 VEAFAEAGRKALGQIDVIVNNAGIMPLSLMSSLKVDEWDRMIEVNIKGVLYGVAAVLPEM 158 Query: 61 LEQQRGHIINLSSVHGLKVFSPGGAVHSASKFALRALCEGVRAELANTPIRSSLITPGAV 120 + GHIIN++S+ L V SP AV+ A+KFA+RA+ +G+R E N +R + I PG V Sbjct: 159 TARASGHIINIASIGALAV-SPTAAVYCATKFAVRAISDGLRQE--NRDLRVTCIHPGVV 215 Query: 121 DTGMQYKTTGSDSARMLAIYKN-AIPAEAVARAITFAMEQPPNVDVNEIVIRPTA 174 ++ + + T +A ++ Y+ A+ +A+ RA+ +A+EQP +VDVNEIVIRPTA Sbjct: 216 ESELAHTITDPAAAELMQSYRAIALKPDAIGRAVRYAIEQPDDVDVNEIVIRPTA 270 >lin0452 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity Lin Listeria innocua Length = 248 Score = 136 bits (342), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 76/178 (42%), Positives = 111/178 (62%), Gaps = 5/178 (2%) Query: 2 KALVEHVVRDYGALDALINCAGIMFVRPLSEINTEEWETTIDLNVKGALWAIAASLPLFL 61 K LVE + YG +DA+ AGIM PLS + +EWE ID+N+KG L IAA LP F+ Sbjct: 70 KKLVELAIERYGKVDAIFLNAGIMPNSPLSALKEDEWEQMIDINIKGVLNGIAAVLPSFI 129 Query: 62 EQQRGHIINLSSVHGLKVFSPGGAVHSASKFALRALCEGVRAELAN--TPIRSSLITPGA 119 Q+ GHII SSV GLK + PGGAV+ A+K+A+R L E +R E A T IR++ I P A Sbjct: 130 AQKSGHIIATSSVAGLKAY-PGGAVYGATKWAVRDLMEVLRMESAQEGTNIRTATIYPAA 188 Query: 120 VDTGMQYKTTGSDSAR-MLAIYKN-AIPAEAVARAITFAMEQPPNVDVNEIVIRPTAQ 175 ++T + T ++ + M +YK + + +A + +A++QP +++VNE + PT Q Sbjct: 189 INTELLETITDKETEQGMTNLYKQYGVTPDRIASIVAYAIDQPEDINVNEFTVGPTTQ 246 >slr0315 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity Syn Synechocystis Length = 244 Score = 135 bits (341), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 74/175 (42%), Positives = 110/175 (62%), Gaps = 4/175 (2%) Query: 1 VKALVEHVVRDYGALDALINCAGIMFVRPLSEINTEEWETTIDLNVKGALWAIAASLPLF 60 VKA VE +G +D + N AG+M + P++ + EEW+ I++N++G L IAA LP+ Sbjct: 70 VKAFVEFANDKFGRVDVIFNNAGVMPLSPMNALKVEEWDNMINVNIRGVLNGIAAGLPIM 129 Query: 61 LEQQRGHIINLSSVHGLKVFSPGGAVHSASKFALRALCEGVRAELANTPIRSSLITPGAV 120 Q G IIN +S+ G V P AV+ A+K+A+ A+ EG+R E N IR + I+PG V Sbjct: 130 EAQGGGQIINTASI-GAHVVVPTAAVYCATKYAVWAISEGLRQESQN--IRVTTISPGVV 186 Query: 121 DTGMQYKTTGSDSARML-AIYKNAIPAEAVARAITFAMEQPPNVDVNEIVIRPTA 174 T + T S +L + K A+ +EA+ARA+ +A+ QP +VDVNEI++RPTA Sbjct: 187 ATELGSDITDESSKGLLEELRKTALTSEAIARAVLYAVSQPDDVDVNEIIVRPTA 241 >Z0343 [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity EcZ Escherichia coli O157:H7 EDL933 Length = 240 Score = 132 bits (331), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 71/174 (40%), Positives = 106/174 (60%), Gaps = 4/174 (2%) Query: 4 LVEHVVRDYGALDALINCAGIMFVRPLSEINTEEWETTIDLNVKGALWAIAASLPLFLEQ 63 V+ + +G +D LIN AG+M + PL+ +EW TID+N+KG LW I A LP+ Q Sbjct: 69 FVQAALDSWGRVDVLINNAGVMPLSPLAAGKQDEWALTIDVNIKGVLWGIGAVLPVMEAQ 128 Query: 64 QRGHIINLSSVHGLKVFSPGGAVHSASKFALRALCEGVRAELANTPIRSSLITPGAVDTG 123 G IINL S+ L V P GAV+ ASKFA+RA+ +G+R E ++ IR + + PG V++ Sbjct: 129 GSGQIINLGSIGALSVV-PTGAVYCASKFAVRAISDGLRQE--SSKIRVTCVNPGVVESE 185 Query: 124 MQYKTTGSDSARMLAIYKN-AIPAEAVARAITFAMEQPPNVDVNEIVIRPTAQA 176 + T ++ + + Y++ A+ +ARA+ +E P +VD EI IRPTA A Sbjct: 186 LASTITHVETMKAMDAYRSVALQPADIARAVRHIIESPESVDTTEITIRPTASA 239