BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0195.0089.p         (386 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

PA4056_1 [H] COG0117 Pyrimidine deaminase Pae Pseudomonas aerugi...   173   8e-43
aq_138_1 [H] COG0117 Pyrimidine deaminase Aae Aquifex aeolicus        169   8e-42
YPO3183_1 [H] COG0117 Pyrimidine deaminase Ype Yersinia pestis        167   3e-41
ribD_1 [H] COG0117 Pyrimidine deaminase Eco Escherichia coli K12      167   4e-41
SMc01772_2 [H] COG1985 Pyrimidine reductase, riboflavin biosynth...   164   3e-40

>PA4056_1 [H] COG0117 Pyrimidine deaminase Pae Pseudomonas aeruginosa
          Length = 146

 Score =  173 bits (438), Expect = 8e-43,   Method: Compositional matrix adjust.
 Identities = 88/143 (61%), Positives = 106/143 (74%)

Query: 22  KAADLRFMQLALALGRRGLGRTWPNPAVGAVIVKDGVIVGRGWTQAGGRPHAEVEALRRA 81
            AAD  +M  AL L R+GL  T PNP VG V+VKDG +VG GW    G PHAEV ALR+A
Sbjct: 2   NAADPLYMARALELARQGLYSTQPNPRVGCVLVKDGQVVGEGWHVRAGEPHAEVHALRQA 61

Query: 82  GDAARGATLYVTLEPCSHFGRSPPCADAVVAAGLARVVSAIEDPNPEVAGQGHAKLRAAG 141
           G+ ARGAT YVTLEPCSHFGR+PPCADA+V AG+ARVV+A++DPNPEVAG+G  +L  AG
Sbjct: 62  GENARGATAYVTLEPCSHFGRTPPCADALVGAGVARVVAAMQDPNPEVAGRGLLRLMQAG 121

Query: 142 IAVDVGLCAAEAARDHAGHFRRI 164
           IAV  G+  AEA   + G  +R+
Sbjct: 122 IAVQSGVLEAEARELNIGFIKRM 144


>aq_138_1 [H] COG0117 Pyrimidine deaminase Aae Aquifex aeolicus
          Length = 146

 Score =  169 bits (429), Expect = 8e-42,   Method: Compositional matrix adjust.
 Identities = 79/140 (56%), Positives = 103/140 (73%)

Query: 25  DLRFMQLALALGRRGLGRTWPNPAVGAVIVKDGVIVGRGWTQAGGRPHAEVEALRRAGDA 84
           D  +M+LAL+L ++  G T PNP VGAV+VK+G IVG G+ +  G+PHAEV AL +AG+ 
Sbjct: 6   DKNYMKLALSLAKKRKGYTHPNPTVGAVVVKEGKIVGLGYHEKAGKPHAEVMALGQAGEK 65

Query: 85  ARGATLYVTLEPCSHFGRSPPCADAVVAAGLARVVSAIEDPNPEVAGQGHAKLRAAGIAV 144
           A+GATLYVTLEPC+HFGR+PPC DA++ +G+ RVV A  DPNP ++G+G  KLR AGI V
Sbjct: 66  AKGATLYVTLEPCTHFGRTPPCTDAIIRSGIKRVVVATLDPNPLMSGKGVEKLRNAGIEV 125

Query: 145 DVGLCAAEAARDHAGHFRRI 164
           DVG+C  EA   +   F  I
Sbjct: 126 DVGVCEEEARELNEDFFTYI 145


>YPO3183_1 [H] COG0117 Pyrimidine deaminase Ype Yersinia pestis
          Length = 144

 Score =  167 bits (424), Expect = 3e-41,   Method: Compositional matrix adjust.
 Identities = 86/141 (60%), Positives = 103/141 (73%)

Query: 25  DLRFMQLALALGRRGLGRTWPNPAVGAVIVKDGVIVGRGWTQAGGRPHAEVEALRRAGDA 84
           D  +M  A  L R G   T PNP VG V+V+DG IVG G+    G PHAEV ALR AG+ 
Sbjct: 4   DEFYMARAFELARLGRFTTSPNPNVGCVLVRDGEIVGEGYHLRAGEPHAEVHALRMAGEK 63

Query: 85  ARGATLYVTLEPCSHFGRSPPCADAVVAAGLARVVSAIEDPNPEVAGQGHAKLRAAGIAV 144
           ARGAT YVTLEPCSH+GR+PPCADA+VAAG+ RVV+A++DPNPEVAG+G  KL+ AGIAV
Sbjct: 64  ARGATAYVTLEPCSHYGRTPPCADALVAAGVIRVVAAMQDPNPEVAGRGLYKLKQAGIAV 123

Query: 145 DVGLCAAEAARDHAGHFRRIR 165
           D GL  AEA   + G  +R+R
Sbjct: 124 DHGLMLAEAEAVNLGFLKRMR 144


>ribD_1 [H] COG0117 Pyrimidine deaminase Eco Escherichia coli K12
          Length = 143

 Score =  167 bits (423), Expect = 4e-41,   Method: Compositional matrix adjust.
 Identities = 82/141 (58%), Positives = 104/141 (73%)

Query: 25  DLRFMQLALALGRRGLGRTWPNPAVGAVIVKDGVIVGRGWTQAGGRPHAEVEALRRAGDA 84
           D  +M  AL L +RG   T PNP VG VIVKDG IVG G+ Q  G PHAEV ALR AG+ 
Sbjct: 3   DEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQRAGEPHAEVHALRMAGEK 62

Query: 85  ARGATLYVTLEPCSHFGRSPPCADAVVAAGLARVVSAIEDPNPEVAGQGHAKLRAAGIAV 144
           A+GAT YVTLEPCSH GR+PPC DA++AAG+ARVV++++DPNP+VAG+G  +L+ AGI V
Sbjct: 63  AKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVASMQDPNPQVAGRGLYRLQQAGIDV 122

Query: 145 DVGLCAAEAARDHAGHFRRIR 165
             GL  +EA + + G  +R+R
Sbjct: 123 SHGLMMSEAEQLNKGFLKRMR 143


>SMc01772_2 [H] COG1985 Pyrimidine reductase, riboflavin biosynthesis Sme
           Sinorhizobium meliloti
          Length = 253

 Score =  164 bits (415), Expect = 3e-40,   Method: Compositional matrix adjust.
 Identities = 108/255 (42%), Positives = 139/255 (54%), Gaps = 41/255 (16%)

Query: 167 KRPHVILKLAVSADDKIAASGHKPVAISGEAARTRVHLLRAQSDAILVGIGTVKADDPLL 226
           KRPHV LKLAVSAD  I   G   V ISG  +R +V +LRA++DAILVGIGT  ADDP L
Sbjct: 2   KRPHVTLKLAVSADGMIGRRGEGQVRISGAVSRAQVQVLRAETDAILVGIGTAIADDPEL 61

Query: 227 TCRLPGMAARSPVRLVLDRALRISGDSRLVHSARETPLWVLTSDMAEAPAAVKLGAAGAQ 286
           T R+PG+  RSPVR+VLDR L +  +S+LV +AR+ PL V+T D A  P++ + GA   +
Sbjct: 62  TVRMPGLEERSPVRIVLDRRLDLPLESKLVRTARDVPLIVVTGD-AGYPSSHEQGAGARR 120

Query: 287 VIRVTASAP----------------QGLD--------------------LPSVLHALAEK 310
                +S P                 G D                    +P +L ALA +
Sbjct: 121 ADEGQSSLPLSSGSTREPVLSPLAEAGTDYDARRGALEAAGAELLSADTIPDLLAALASR 180

Query: 311 GISRLLVEGGSRVANSFVAGGLVDEIWLLRGPDAIGAGGVPALDAMPLDAITQSPAFRLR 370
           GIS LLVEGG+R A SF+   LVD I L  GP AIG GG+    + P    +    F LR
Sbjct: 181 GISSLLVEGGARAARSFLDADLVDRILLFTGPAAIGEGGI----SSPFQRTSVPEGFTLR 236

Query: 371 ASETLGEDVLTIYDR 385
            +   G+D+   Y+R
Sbjct: 237 RTARYGDDIFEDYER 251