BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0195.0003.p (481 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr6916 [C] COG0277 FAD/FMN-containing dehydrogenases Mlo Mesorh... 708 0.0 BMEII1064 [C] COG0277 FAD/FMN-containing dehydrogenases Bme Bruc... 692 0.0 PA5355 [C] COG0277 FAD/FMN-containing dehydrogenases Pae Pseudom... 520 e-147 glcD [C] COG0277 FAD/FMN-containing dehydrogenases Eco Escherich... 513 e-145 RSc2666 [C] COG0277 FAD/FMN-containing dehydrogenases Rso Ralsto... 501 e-141 >mlr6916 [C] COG0277 FAD/FMN-containing dehydrogenases Mlo Mesorhizobium loti Length = 475 Score = 708 bits (1828), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/475 (73%), Positives = 397/475 (83%), Gaps = 13/475 (2%) Query: 20 LRAIVPGEGVIDSAAEMLAYESDGLTAYRQPPMVVVLPDTTEQVSKVLKYCQGQGIKVVP 79 +R IVPGEGV+D+A M A+ESDGLTAYRQ P+VVVLP+T QVS+VLKYC + I+VVP Sbjct: 1 MRIIVPGEGVVDAANAMRAFESDGLTAYRQLPLVVVLPETVAQVSRVLKYCNDRNIRVVP 60 Query: 80 RGSGTSLSGGALPLADGVLLGLGKFKRIREIDFDNRVVVTEPGVTNLAISQAVAHAGFYY 139 RGSGTSLSGGALPL D VLL + +F RI IDF NR+VV +PGVTNL I+ AV GFYY Sbjct: 61 RGSGTSLSGGALPLEDAVLLVMSRFNRILAIDFPNRIVVAQPGVTNLGITTAVEQEGFYY 120 Query: 140 APDPSSQIACSIGGNVAENSGGVHCLKYGMTTNNVLGCEIVLMSGEILRIGGKSAENAGY 199 APDPSSQIACSIGGNVAENSGGVHCLKYG+T NNVLG E+VLM+GE++R+GG + GY Sbjct: 121 APDPSSQIACSIGGNVAENSGGVHCLKYGLTANNVLGIEMVLMNGEVVRLGGSHLDAEGY 180 Query: 200 DLMGIITGSEGLLGVITEITVRILQKPETARALMVGFAEVEAAGECVARIIGA------- 252 DL+G++TGSEGLLGV+TE+TVRIL+KPETARAL++GF E G+CVA IIGA Sbjct: 181 DLLGVMTGSEGLLGVVTEVTVRILKKPETARALLIGFPTSEQGGQCVADIIGAGIIPGGM 240 Query: 253 ------GXHAAEAFVHAGYPLDVEALLIIELDGPQVEVDELIKRVEAIAQGCGSTSCQIS 306 HAAE FVHAGYPLDVEALLI+ELDGP VEVD LI VEAIA GST+C+IS Sbjct: 241 EMMDRPAIHAAEDFVHAGYPLDVEALLIVELDGPGVEVDHLITAVEAIAISNGSTTCRIS 300 Query: 307 TSEAERNLFWAGRKAAFPAVGRISPDYLCMDGTIPRGALPKALARIRDLSEKYGLGVANV 366 SEAER FWAGRKAAFPAVGRISPDY CMDGTIPR LP+ LA +R+LSEKYGLGVANV Sbjct: 301 QSEAERLSFWAGRKAAFPAVGRISPDYYCMDGTIPRKELPRVLAGMRELSEKYGLGVANV 360 Query: 367 FHAGDGNLHPLILYDANKPGEIEKAEAFGADILRCCVELGGVLTGEHGVGIEKRDLMPDM 426 FHAGDGNLHPLILYDAN PGE++KAE+FGADILR CV++GGVLTGEHGVG+EKRDLMP+M Sbjct: 361 FHAGDGNLHPLILYDANVPGELDKAESFGADILRLCVKVGGVLTGEHGVGVEKRDLMPEM 420 Query: 427 FTEIDLNQQQRLKCAFDAEGLLNPGKVFPTLHRCAELGRVHVHAGKLAFPDIPRF 481 F ++DL+QQ R+KCAFD LLNPGKVFP L RCAELGR+HVH G++AFPDIPRF Sbjct: 421 FNQVDLDQQMRIKCAFDPNHLLNPGKVFPQLRRCAELGRMHVHRGQVAFPDIPRF 475 >BMEII1064 [C] COG0277 FAD/FMN-containing dehydrogenases Bme Brucella melitensis Length = 541 Score = 692 bits (1786), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/480 (70%), Positives = 393/480 (81%), Gaps = 13/480 (2%) Query: 15 EIAAALRAIVPGEGVIDSAAEMLAYESDGLTAYRQPPMVVVLPDTTEQVSKVLKYCQGQG 74 +I A LR IVPGEGV+D+ M +E+DGLTA+RQ P+VVVLP+T EQV++VL+YC Sbjct: 62 QIVADLRVIVPGEGVVDTVNAMRVFETDGLTAHRQLPLVVVLPETVEQVAQVLRYCHDNA 121 Query: 75 IKVVPRGSGTSLSGGALPLADGVLLGLGKFKRIREIDFDNRVVVTEPGVTNLAISQAVAH 134 I+VVPRG+GTSLSGG++PL D VLL + +F RI EID+ NRV V +PGVTNL I++AV H Sbjct: 122 IRVVPRGAGTSLSGGSMPLEDAVLLVMSRFNRILEIDYPNRVAVVQPGVTNLGITKAVEH 181 Query: 135 AGFYYAPDPSSQIACSIGGNVAENSGGVHCLKYGMTTNNVLGCEIVLMSGEILRIGGKSA 194 GFYYAPDPSSQIACSIGGNVAEN+GGVHCLKYG+T NNVLG E+VL++GE++R+GGK Sbjct: 182 EGFYYAPDPSSQIACSIGGNVAENAGGVHCLKYGLTANNVLGIEMVLITGEVMRLGGKHL 241 Query: 195 ENAGYDLMGIITGSEGLLGVITEITVRILQKPETARALMVGFAEVEAAGECVARIIGA-- 252 ++ YDL+G++TGSEGLLGV+TEITVRILQKPETARA+MVGF E AG+CVA IIGA Sbjct: 242 DSEAYDLLGLMTGSEGLLGVVTEITVRILQKPETARAIMVGFPSSEQAGQCVADIIGAGI 301 Query: 253 -----------GXHAAEAFVHAGYPLDVEALLIIELDGPQVEVDELIKRVEAIAQGCGST 301 AAE FV GYPLDVEALLI+ELDGP VEVD L+ RVE IA GST Sbjct: 302 IPGGMEMMDRPAIKAAEDFVRVGYPLDVEALLIVELDGPPVEVDYLLGRVEKIALQNGST 361 Query: 302 SCQISTSEAERNLFWAGRKAAFPAVGRISPDYLCMDGTIPRGALPKALARIRDLSEKYGL 361 +C +S SE +R FWAGRKAAFPAVGRISPDYLCMDGTIPR LP+ L+ +R LSEKYGL Sbjct: 362 TCTLSQSEEQRLAFWAGRKAAFPAVGRISPDYLCMDGTIPRKELPRVLSGMRALSEKYGL 421 Query: 362 GVANVFHAGDGNLHPLILYDANKPGEIEKAEAFGADILRCCVELGGVLTGEHGVGIEKRD 421 VANVFHAGDGNLHPLILYDAN PGE+E AE FGADILR CV++GGVLTGEHGVGIEKRD Sbjct: 422 RVANVFHAGDGNLHPLILYDANNPGELEAAEDFGADILRLCVKVGGVLTGEHGVGIEKRD 481 Query: 422 LMPDMFTEIDLNQQQRLKCAFDAEGLLNPGKVFPTLHRCAELGRVHVHAGKLAFPDIPRF 481 LMP+MF E DL+QQ R+KCAFDA+ LLNPGKVFP L RCAELGR+HV G LAFPD+PRF Sbjct: 482 LMPEMFNETDLDQQMRVKCAFDAKHLLNPGKVFPQLRRCAELGRMHVSRGALAFPDLPRF 541 >PA5355 [C] COG0277 FAD/FMN-containing dehydrogenases Pae Pseudomonas aeruginosa Length = 499 Score = 520 bits (1338), Expect = e-147, Method: Compositional matrix adjust. Identities = 264/479 (55%), Positives = 334/479 (69%), Gaps = 13/479 (2%) Query: 16 IAAALRAIVPGEGVIDSAAEMLAYESDGLTAYRQPPMVVVLPDTTEQVSKVLKYCQGQGI 75 + A LR +P ++ +A ++ YE DGL+AYR P++V LP+ EQV +L C + Sbjct: 21 LLAELRLRLPDLELLHAAEDLRPYECDGLSAYRCTPLLVALPERIEQVQGLLALCHRLKV 80 Query: 76 KVVPRGSGTSLSGGALPLADGVLLGLGKFKRIREIDFDNRVVVTEPGVTNLAISQAVAHA 135 VV RG+GT LSGGALPL +GVLL + +F+RI EID R +PGV NLAISQA A Sbjct: 81 PVVARGAGTGLSGGALPLENGVLLVMARFRRILEIDPLGRFARVQPGVRNLAISQAAAPH 140 Query: 136 GFYYAPDPSSQIACSIGGNVAENSGGVHCLKYGMTTNNVLGCEIVLMSGEILRIGGKSAE 195 G YYAPDPSSQIACSIGGNVAEN+GGVHCLKYG+T +N+L +IV + GE L +G + + Sbjct: 141 GLYYAPDPSSQIACSIGGNVAENAGGVHCLKYGLTVHNLLQVDIVTLEGERLSLGSSALD 200 Query: 196 NAGYDLMGIITGSEGLLGVITEITVRILQKPETARALMVGFAEVEAAGECVARIIGAGX- 254 +AG+DL+ + TGSEGLLGV+ E+TVR+L +P A+ L+ F +VE+AG VA +IGAG Sbjct: 201 SAGFDLLALFTGSEGLLGVVVEVTVRLLPRPPVAKVLLASFDDVESAGRAVADLIGAGIV 260 Query: 255 ------------HAAEAFVHAGYPLDVEALLIIELDGPQVEVDELIKRVEAIAQGCGSTS 302 AAE F+HAGYP+D A+L+ ELDG + +V E +RV + + G+TS Sbjct: 261 PAGLEMMDNLSIRAAEDFIHAGYPVDAAAILLCELDGVEADVHEDCERVRELFEAAGATS 320 Query: 303 CQISTSEAERNLFWAGRKAAFPAVGRISPDYLCMDGTIPRGALPKALARIRDLSEKYGLG 362 + + EAER FWAGRK AFPAVGRISPDY CMDG+IPR LP+ L I +LS +YGL Sbjct: 321 VRQAQDEAERQRFWAGRKNAFPAVGRISPDYYCMDGSIPRRELPRVLHGIAELSREYGLR 380 Query: 363 VANVFHAGDGNLHPLILYDANKPGEIEKAEAFGADILRCCVELGGVLTGEHGVGIEKRDL 422 VANVFHAGDGN+HPLIL+DAN GE+E+AEA G IL CV +GG +TGEHGVG EK + Sbjct: 381 VANVFHAGDGNMHPLILFDANLAGELERAEALGGRILELCVAVGGSITGEHGVGREKINQ 440 Query: 423 MPDMFTEIDLNQQQRLKCAFDAEGLLNPGKVFPTLHRCAELGRVHVHAGKLAFPDIPRF 481 M F +L +K AFD GLLNPGK PTLHRCAE G +HVH G+L FP++ RF Sbjct: 441 MCAQFNADELTLFHAVKAAFDPAGLLNPGKNVPTLHRCAEFGAMHVHHGRLPFPELERF 499 >glcD [C] COG0277 FAD/FMN-containing dehydrogenases Eco Escherichia coli K12 Length = 499 Score = 513 bits (1321), Expect = e-145, Method: Compositional matrix adjust. Identities = 261/479 (54%), Positives = 326/479 (68%), Gaps = 13/479 (2%) Query: 16 IAAALRAIVPGEGVIDSAAEMLAYESDGLTAYRQPPMVVVLPDTTEQVSKVLKYCQGQGI 75 + ALR VPG ++ + E++ YE DGL+AYR P++VVLP EQV+ +L C + Sbjct: 21 VLMALREHVPGLEILHTDEEIIPYECDGLSAYRTRPLLVVLPKQMEQVTAILAVCHRLRV 80 Query: 76 KVVPRGSGTSLSGGALPLADGVLLGLGKFKRIREIDFDNRVVVTEPGVTNLAISQAVAHA 135 VV RG+GT LSGGALPL GVLL + +FK I +I+ R +PGV NLAISQAVA Sbjct: 81 PVVTRGAGTGLSGGALPLEKGVLLVMARFKEILDINPVGRRARVQPGVRNLAISQAVAPH 140 Query: 136 GFYYAPDPSSQIACSIGGNVAENSGGVHCLKYGMTTNNVLGCEIVLMSGEILRIGGKSAE 195 YYAPDPSSQIACSIGGNVAEN+GGVHCLKYG+T +N+L E+ + GE L +G + + Sbjct: 141 NLYYAPDPSSQIACSIGGNVAENAGGVHCLKYGLTVHNLLKIEVQTLDGEALTLGSDALD 200 Query: 196 NAGYDLMGIITGSEGLLGVITEITVRILQKPETARALMVGFAEVEAAGECVARIIGAGX- 254 + G+DL+ + TGSEG+LGV TE+TV++L KP AR L+ F VE AG V II G Sbjct: 201 SPGFDLLALFTGSEGMLGVTTEVTVKLLPKPPVARVLLASFDSVEKAGLAVGDIIANGII 260 Query: 255 ------------HAAEAFVHAGYPLDVEALLIIELDGPQVEVDELIKRVEAIAQGCGSTS 302 AAE F+HAGYP+D EA+L+ ELDG + +V E +RV I G+T Sbjct: 261 PGGLEMMDNLSIRAAEDFIHAGYPVDAEAILLCELDGVESDVQEDCERVNDILLKAGATD 320 Query: 303 CQISTSEAERNLFWAGRKAAFPAVGRISPDYLCMDGTIPRGALPKALARIRDLSEKYGLG 362 +++ EAER FWAGRK AFPAVGRISPDY CMDGTIPR ALP L I LS++Y L Sbjct: 321 VRLAQDEAERVRFWAGRKNAFPAVGRISPDYYCMDGTIPRRALPGVLEGIARLSQQYDLR 380 Query: 363 VANVFHAGDGNLHPLILYDANKPGEIEKAEAFGADILRCCVELGGVLTGEHGVGIEKRDL 422 VANVFHAGDGN+HPLIL+DAN+PGE +AE G IL CVE+GG ++GEHG+G EK + Sbjct: 381 VANVFHAGDGNMHPLILFDANEPGEFARAEELGGKILELCVEVGGSISGEHGIGREKINQ 440 Query: 423 MPDMFTEIDLNQQQRLKCAFDAEGLLNPGKVFPTLHRCAELGRVHVHAGKLAFPDIPRF 481 M F ++ +K AFD +GLLNPGK PTLHRCAE G +HVH G L FP++ RF Sbjct: 441 MCAQFNSDEITTFHAVKAAFDPDGLLNPGKNIPTLHRCAEFGAMHVHHGHLPFPELERF 499 >RSc2666 [C] COG0277 FAD/FMN-containing dehydrogenases Rso Ralstonia solanacearum Length = 497 Score = 501 bits (1290), Expect = e-141, Method: Compositional matrix adjust. Identities = 251/485 (51%), Positives = 321/485 (66%), Gaps = 13/485 (2%) Query: 10 AAALAEIAAALRAIVPGEGVIDSAAEMLAYESDGLTAYRQPPMVVVLPDTTEQVSKVLKY 69 +A AE+ AAL ++P + ++ + YE DGL AYRQ P+ V LPD+ QV ++L+ Sbjct: 13 SAVQAELIAALSPLMPADALLWEREDTTPYECDGLAAYRQVPLAVALPDSEAQVVEILRA 72 Query: 70 CQGQGIKVVPRGSGTSLSGGALPLADGVLLGLGKFKRIREIDFDNRVVVTEPGVTNLAIS 129 C G+ VVPRG+GTSLSGGA+P G++L L KFKRI ++D R +PGV NLAIS Sbjct: 73 CHRLGVPVVPRGAGTSLSGGAMPTPGGLVLSLAKFKRILKLDPHTRTAAVQPGVRNLAIS 132 Query: 130 QAVAHAGFYYAPDPSSQIACSIGGNVAENSGGVHCLKYGMTTNNVLGCEIVLMSGEILRI 189 +A A G YYAPDPSSQIAC+IGGNV+ENSGGVHCLKYG+T +NVL V+M GE++ Sbjct: 133 EAAAPHGLYYAPDPSSQIACTIGGNVSENSGGVHCLKYGLTVHNVLRVRAVMMDGEVVEF 192 Query: 190 GGKSAENAGYDLMGIITGSEGLLGVITEITVRILQKPETARALMVGFAEVEAAGECVARI 249 G ++ + G DL+ + GSEG+L V+TE+TVR++ KP+ A+ +M F +VEA G VA + Sbjct: 193 GSEAPDAPGLDLLAAVIGSEGMLAVVTEVTVRLVPKPQLAQVIMASFDDVEAGGNAVAEV 252 Query: 250 IGAG-------------XHAAEAFVHAGYPLDVEALLIIELDGPQVEVDELIKRVEAIAQ 296 I AG A E FV AGY LD A+L+ E DG EV E I R+ + + Sbjct: 253 IAAGIIPAGLEMMDKPATAAVEEFVRAGYDLDAAAILLCESDGTPEEVAEEIARMSEVLR 312 Query: 297 GCGSTSCQISTSEAERNLFWAGRKAAFPAVGRISPDYLCMDGTIPRGALPKALARIRDLS 356 G+T Q+S SEAER FW+GRK AFPA GRISPDY CMDGTIPR + L RI+ + Sbjct: 313 ASGATRIQVSQSEAERLKFWSGRKNAFPAAGRISPDYYCMDGTIPRKHIGTLLKRIQQME 372 Query: 357 EKYGLGVANVFHAGDGNLHPLILYDANKPGEIEKAEAFGADILRCCVELGGVLTGEHGVG 416 + Y L NVFHAGDGN+HPLIL++ E +AE FGADIL CVELGG +TGEHGVG Sbjct: 373 QNYALRCINVFHAGDGNMHPLILFNGEDQDEWHRAELFGADILETCVELGGTVTGEHGVG 432 Query: 417 IEKRDLMPDMFTEIDLNQQQRLKCAFDAEGLLNPGKVFPTLHRCAELGRVHVHAGKLAFP 476 +EK + M F+ + + R+K AFD LLNP K PTL RCAE G++HV G L P Sbjct: 433 VEKLNSMCVQFSAEERDAFLRVKAAFDPARLLNPDKAIPTLARCAEYGKLHVRNGLLPHP 492 Query: 477 DIPRF 481 D+PRF Sbjct: 493 DLPRF 497