BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0193.0079.p (252 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll7191 [IQR] COG1028 Dehydrogenases with different specificitie... 290 2e-78 SMc00880 [IQR] COG1028 Dehydrogenases with different specificiti... 264 1e-70 AGc1273 [IQR] COG1028 Dehydrogenases with different specificitie... 235 7e-62 mlr4741 [IQR] COG1028 Dehydrogenases with different specificitie... 233 4e-61 CC0821 [IQR] COG1028 Dehydrogenases with different specificities... 224 2e-58 >mll7191 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 258 Score = 290 bits (743), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 137/251 (54%), Positives = 176/251 (70%), Gaps = 2/251 (0%) Query: 4 AIYPSLKDRTVLVTGGGSGIGEAIVRQFIGQGARVGFIDIDLTASEQLLSDLGAQARVH- 62 AIYPSLK R+V +TGGGSGIGE++VR F QG+RV F+D+ S L+ + A+ Sbjct: 8 AIYPSLKGRSVFITGGGSGIGESLVRHFCAQGSRVAFVDLSEEPSRHLVEAIAAEGHPAP 67 Query: 63 -FEHADLRDIGALRRAVAGIRETLGPVTILVNNAARDDRHAIEDVTPEFWDERIAVNLKH 121 F DLRD+ L+ A A + GP+ +L NNA DDRH +DVT +WD+R+AVNL+H Sbjct: 68 LFIPCDLRDVEQLQAATAQAMQHNGPIQVLCNNAGNDDRHQTKDVTVAYWDDRMAVNLRH 127 Query: 122 QFFSAQAVAPDMKQAGGGSIVNIGSVSWVIGQGNMPCYTTAKSAVQGLTRALARDLGPHN 181 QFF+AQAV P M GGGSI+N GS++W++G + P Y TAK+AV G+TRALAR+LGP Sbjct: 128 QFFAAQAVRPQMSAQGGGSIINFGSITWMVGDPDCPAYVTAKAAVYGMTRALARELGPER 187 Query: 182 IRVNSILPGWIMTRRQQDLWLTPEGVAELMQRQCLKRKLLPDDIARVVLFFAADDSGACT 241 IRVN ++PGW+MT RQ LWL P G ++ +RQCL +L P DIAR+ LF AADDS CT Sbjct: 188 IRVNCMVPGWVMTERQMRLWLNPAGERQIAERQCLPDRLQPADIARMALFLAADDSRMCT 247 Query: 242 NQSHIVDGGWV 252 +Q IVD GWV Sbjct: 248 SQQFIVDAGWV 258 >SMc00880 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 256 Score = 264 bits (675), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 133/247 (53%), Positives = 171/247 (69%), Gaps = 2/247 (0%) Query: 6 YPSLKDRTVLVTGGGSGIGEAIVRQFIGQGARVGFIDIDLTASEQLLSDLGAQA--RVHF 63 +P L+DR VLVTGGGSGIG A+V F QGARV F+DI +S L + AQ HF Sbjct: 8 FPDLRDRGVLVTGGGSGIGAALVEAFARQGARVAFVDIAAESSLALCEKVAAQTGQAPHF 67 Query: 64 EHADLRDIGALRRAVAGIRETLGPVTILVNNAARDDRHAIEDVTPEFWDERIAVNLKHQF 123 ADLR++ A+R A LG V +LVNNAARDDR A+E VT E WDE ++VNL+H F Sbjct: 68 IQADLRNVEAVRAAADEAVAKLGSVRVLVNNAARDDRQALEAVTEESWDESLSVNLRHLF 127 Query: 124 FSAQAVAPDMKQAGGGSIVNIGSVSWVIGQGNMPCYTTAKSAVQGLTRALARDLGPHNIR 183 F QAVAP M++ GGGSIVN S+++++ +P Y+TAK+ + GLT++LA LGP NIR Sbjct: 128 FMCQAVAPHMQRQGGGSIVNFSSIAFLLNMPEIPAYSTAKAGIIGLTKSLAGKLGPDNIR 187 Query: 184 VNSILPGWIMTRRQQDLWLTPEGVAELMQRQCLKRKLLPDDIARVVLFFAADDSGACTNQ 243 VN+ILPG I+T RQ+ LWLT E +A + +RQCLKR L+ DD+ LF A+D S A T Q Sbjct: 188 VNAILPGMIVTERQRRLWLTEESIARMQERQCLKRMLVADDLVGPCLFLASDSSAAMTAQ 247 Query: 244 SHIVDGG 250 + I+DGG Sbjct: 248 AMIIDGG 254 >AGc1273 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 260 Score = 235 bits (600), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 127/254 (50%), Positives = 162/254 (63%), Gaps = 2/254 (0%) Query: 1 MQGAIYPSLKDRTVLVTGGGSGIGEAIVRQFIGQGARVGFIDIDLTASEQLLSDLGAQAR 60 M A +P LKD VLVTGGGSGIG ++V F QGA+V FIDI S L+ L A Sbjct: 7 MMQAQFPDLKDAGVLVTGGGSGIGASLVEAFAMQGAKVSFIDIAEQPSIALVERLAATVP 66 Query: 61 --VHFEHADLRDIGALRRAVAGIRETLGPVTILVNNAARDDRHAIEDVTPEFWDERIAVN 118 VH+ ADL DI A++R V G + +LVNNAA DDRH I+ VT +WD AVN Sbjct: 67 HPVHYFRADLSDIDAIKRTVDMAASATGGIKVLVNNAAWDDRHDIDSVTEAYWDANQAVN 126 Query: 119 LKHQFFSAQAVAPDMKQAGGGSIVNIGSVSWVIGQGNMPCYTTAKSAVQGLTRALARDLG 178 LK FF+ QA P ++QA SIVN S+S+++ G +P Y AK+ + GLT++LA LG Sbjct: 127 LKQMFFTVQAALPHLRQAKDASIVNFSSISFLLNMGELPSYAAAKAGIIGLTKSLAGRLG 186 Query: 179 PHNIRVNSILPGWIMTRRQQDLWLTPEGVAELMQRQCLKRKLLPDDIARVVLFFAADDSG 238 P NIRVN++LPG I+T RQ++LWLT EG+ RQCLKR L+ D++ LF A+ S Sbjct: 187 PENIRVNTLLPGMIVTERQKELWLTDEGITATTARQCLKRTLVAADLSGPCLFLASSASS 246 Query: 239 ACTNQSHIVDGGWV 252 A T QS IVDGG + Sbjct: 247 AITAQSIIVDGGLL 260 >mlr4741 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 254 Score = 233 bits (593), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 127/254 (50%), Positives = 166/254 (65%), Gaps = 2/254 (0%) Query: 1 MQGAIYPSLKDRTVLVTGGGSGIGEAIVRQFIGQGARVGFIDIDLTASEQLLSDLGAQA- 59 M A + LK +VL+TGGGSGIG A+ F+ QGA V FIDI S L + + Sbjct: 1 MPSADFADLKGASVLITGGGSGIGAALTEGFVRQGANVAFIDIAEGPSTLLADRIEKEFG 60 Query: 60 -RVHFEHADLRDIGALRRAVAGIRETLGPVTILVNNAARDDRHAIEDVTPEFWDERIAVN 118 R + DLRDI ALR + A E G VT+L+NNAA D+RHA+EDVT EFWD A+N Sbjct: 61 RRPLYLKTDLRDIEALRASAARAAEAHGDVTVLINNAAWDERHAVEDVTVEFWDNNQAIN 120 Query: 119 LKHQFFSAQAVAPDMKQAGGGSIVNIGSVSWVIGQGNMPCYTTAKSAVQGLTRALARDLG 178 L+ FF+AQAVAP MK+AGGGSI+N S S++I +MP YT AK+ + GLT+ LA LG Sbjct: 121 LRPHFFTAQAVAPGMKRAGGGSIINFTSTSYLINHPDMPAYTAAKAGILGLTKGLAGKLG 180 Query: 179 PHNIRVNSILPGWIMTRRQQDLWLTPEGVAELMQRQCLKRKLLPDDIARVVLFFAADDSG 238 P IRVN++ PGW++T RQQ+ W+T +A + +QC+K + PDD+ VLF A+D S Sbjct: 181 PDRIRVNAVAPGWVITERQQERWVTEGALAAHVAKQCIKEVMRPDDMVGTVLFLASDASR 240 Query: 239 ACTNQSHIVDGGWV 252 T Q IVDGG++ Sbjct: 241 MLTAQMLIVDGGFL 254 >CC0821 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 248 Score = 224 bits (571), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 119/252 (47%), Positives = 170/252 (67%), Gaps = 6/252 (2%) Query: 1 MQGAIYPSLKDRTVLVTGGGSGIGEAIVRQFIGQGARVGFIDIDLTASEQLLSDL-GAQA 59 M AIYPSLK + V++TGGGSGIG + F QGA V F+DI S L ++L G+ Sbjct: 1 MSSAIYPSLKGKRVVITGGGSGIGAGLTAGFARQGAEVIFLDIADEDSRALEAELAGSPI 60 Query: 60 RVHFEHADLRDIGALRRAVAGIRETLGPVTILVNNAARDDRHAIEDVTPEFWDERIAVNL 119 ++ DL ++ A++ A I G V +LVNNA DDRH + DVT +WDERI VNL Sbjct: 61 PPVYKRCDLMNLEAIKAVFAEI----GDVDVLVNNAGNDDRHKLADVTGAYWDERINVNL 116 Query: 120 KHQFFSAQAVAPDMKQAGGGSIVNIGSVSWVIGQGNMPCYTTAKSAVQGLTRALARDLGP 179 +H F QAVAP MK+ GGG+++N GS+SW +G ++ Y TAK+ ++G+TRALAR+LGP Sbjct: 117 RHMLFCTQAVAPGMKKRGGGAVINFGSISWHLGLEDLVLYETAKAGIEGMTRALARELGP 176 Query: 180 HNIRVNSILPGWIMTRRQQDLWLTPEGVAELMQRQCLKRKLLPDDIARVVLFFAADDSGA 239 +IRV ++PG + T+RQ+ W TPEG A+++ QCLK +++P+++A +VLF A+DD+ Sbjct: 177 DDIRVTCVVPGNVKTKRQEK-WYTPEGEAQIVAAQCLKGRIVPENVAALVLFLASDDASL 235 Query: 240 CTNQSHIVDGGW 251 CT + +D GW Sbjct: 236 CTGHEYWIDAGW 247