BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0193.0074.p (280 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll5998 Non COG 344 1e-94 PA0193 [Q] COG2175 Probable taurine catabolism dioxygenase Pae P... 340 2e-93 Rv3406 [Q] COG2175 Probable taurine catabolism dioxygenase Mtu M... 279 4e-75 MT3514 [Q] COG2175 Probable taurine catabolism dioxygenase MtC M... 279 4e-75 PA3935 [Q] COG2175 Probable taurine catabolism dioxygenase Pae P... 181 2e-45 >mll5998 Non COG Length = 295 Score = 344 bits (883), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 175/270 (64%), Positives = 202/270 (74%), Gaps = 15/270 (5%) Query: 1 VKLSGDLPGALIRAINQVLLEHKVIFFRDQEHLDDAEQERFAVRLGKLVPHPTIGPSKGT 60 VKLS DLP I AIN ++LEHKV+FFRDQ HLDDA QERFA+R GKL P+P +GT Sbjct: 30 VKLSADLPDRTIAAINGLVLEHKVVFFRDQGHLDDAGQERFALRFGKLSPYP-----EGT 84 Query: 61 SSILELDSGRGGGRADQWHTDVTFVDAYPKISVLRGVVIPPYGGDTVWSNTAAAYLDLPA 120 + I ++D+ RG A WH D + +DAYPKI+VLRGV IP GGDTVWSNTAAAYLDLP Sbjct: 85 TPIYDIDTARGDTGAYVWHIDWSCMDAYPKIAVLRGVTIPLVGGDTVWSNTAAAYLDLPL 144 Query: 121 PLRKLADELWAIHSNAYDYAVKSRATDADRKHFDEVFTGTIYETEHPVVRVHPETGEHTL 180 PL++LA+ELWA+HS Y S E TG + ETEHPVVRVHPETGE TL Sbjct: 145 PLQRLANELWAVHSFPGSYLRSS----------TEPNTGPMIETEHPVVRVHPETGERTL 194 Query: 181 VLGNFVQRFVGLPKYDGQKLFDLFQSHITAPENTVRWSWRAGDVAIWDNRATQHYAVNDY 240 VLG +V RFVG+ KYDGQ+L DLF+SH+TA ENTVRW W+ GD+AIWDNRAT H A D Sbjct: 195 VLGVYVTRFVGISKYDGQRLLDLFESHVTAQENTVRWKWKEGDIAIWDNRATMHCATKDC 254 Query: 241 GDQHRVVRRATIDGEVPVSVDGRHSVTRIK 270 GDQ RVVRRATI+GEVPVSVDGR+SV R K Sbjct: 255 GDQRRVVRRATIEGEVPVSVDGRYSVVRSK 284 >PA0193 [Q] COG2175 Probable taurine catabolism dioxygenase Pae Pseudomonas aeruginosa Length = 300 Score = 340 bits (873), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 168/268 (62%), Positives = 204/268 (76%), Gaps = 2/268 (0%) Query: 1 VKLSGDLPGALIRAINQVLLEHKVIFFRDQEHLDDAEQERFAVRLGKLVPHPTIGPSKGT 60 V LSG+L A + AI L+ HKVIFFRDQ HLDD QE FA LG+ V HPT+ +GT Sbjct: 30 VTLSGELDAATVEAIQAALVRHKVIFFRDQSHLDDQTQEAFAHLLGEPVAHPTVPSREGT 89 Query: 61 SSILELDSGRGGGRADQWHTDVTFVDAYPKISVLRGVVIPPYGGDTVWSNTAAAYLDLPA 120 +LELD G G RA+ WHTDVTFV+AYPK S+LR VV P GGDTVW+NTA+AY DLPA Sbjct: 90 RFLLELD-GAEGRRANSWHTDVTFVEAYPKASILRSVVAPESGGDTVWANTASAYADLPA 148 Query: 121 PLRKLADELWAIHSNAYDYA-VKSRATDADRKHFDEVFTGTIYETEHPVVRVHPETGEHT 179 LR+LAD LWA+HSN YDYA VK A+ +++ +VFT T+YETEHPVVRVHP++GE T Sbjct: 149 ELRELADRLWAVHSNEYDYAGVKPSASVEQLENYRKVFTSTVYETEHPVVRVHPQSGERT 208 Query: 180 LVLGNFVQRFVGLPKYDGQKLFDLFQSHITAPENTVRWSWRAGDVAIWDNRATQHYAVND 239 L+LG+FV+R GL ++D LF + Q H+T ENTVRW W+AGDVAIWDNRATQHYA++D Sbjct: 209 LLLGHFVKRLKGLSQHDSAHLFAVLQGHVTRLENTVRWRWQAGDVAIWDNRATQHYAIDD 268 Query: 240 YGDQHRVVRRATIDGEVPVSVDGRHSVT 267 YGDQ RVVRR T+ G+VPV +DG+ S T Sbjct: 269 YGDQPRVVRRVTLGGDVPVGIDGQRSRT 296 >Rv3406 [Q] COG2175 Probable taurine catabolism dioxygenase Mtu Mycobacterium tuberculosis H37Rv Length = 295 Score = 279 bits (714), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 144/275 (52%), Positives = 186/275 (67%), Gaps = 6/275 (2%) Query: 1 VKLSGDLPGALIRAINQVLLEHKVIFFRDQEHLDDAEQERFAVRLGKLVPHPT-IGPSKG 59 V+L GDL A + I LL HKV+FFR Q LDDAEQ FA LG + HP I + Sbjct: 21 VRLGGDLDPAAVNEIRAALLAHKVVFFRGQHQLDDAEQLAFAGLLGTPIGHPAAIALADD 80 Query: 60 TSSILELDSGRGGGRADQWHTDVTFVDAYPKISVLRGVVIPPYGGDTVWSNTAAAYLDLP 119 I ++S G +A++WHTDVTF YP SVLR V +P YGG T+W+NTAAAY +LP Sbjct: 81 APIITPINSEFG--KANRWHTDVTFAANYPAASVLRAVSLPSYGGSTLWANTAAAYAELP 138 Query: 120 APLRKLADELWAIHSNAYDYAVKSRATDADRKHFDEVFTGTIYETEHPVVRVHPETGEHT 179 PL+ L + LWA+H+N YDY V ++ A ++ F +VF + TEHPVVRVHPETGE T Sbjct: 139 EPLKCLTENLWALHTNRYDY-VTTKPLTAAQRAFRQVFEKPDFRTEHPVVRVHPETGERT 197 Query: 180 LVLGNFVQRFVGLPKYDGQKLFDLFQSHITAPENTVRWSWRAGDVAIWDNRATQHYAVND 239 L+ G+FV+ FVGL ++ + LF++ Q IT PENT+RW+W GDVAIWDNRATQH A++D Sbjct: 198 LLAGDFVRSFVGLDSHESRVLFEVLQRRITMPENTIRWNWAPGDVAIWDNRATQHRAIDD 257 Query: 240 YGDQHRVVRRATIDGEVPVSVDGRHSVTRIKSPKP 274 Y DQHR++ R T+ G+VPV V G+ S R+ S P Sbjct: 258 YDDQHRLMHRVTLMGDVPVDVYGQAS--RVISGAP 290 >MT3514 [Q] COG2175 Probable taurine catabolism dioxygenase MtC Mycobacterium tuberculosis CDC1551 Length = 295 Score = 279 bits (714), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 144/275 (52%), Positives = 186/275 (67%), Gaps = 6/275 (2%) Query: 1 VKLSGDLPGALIRAINQVLLEHKVIFFRDQEHLDDAEQERFAVRLGKLVPHPT-IGPSKG 59 V+L GDL A + I LL HKV+FFR Q LDDAEQ FA LG + HP I + Sbjct: 21 VRLGGDLDPAAVNEIRAALLAHKVVFFRGQHQLDDAEQLAFAGLLGTPIGHPAAIALADD 80 Query: 60 TSSILELDSGRGGGRADQWHTDVTFVDAYPKISVLRGVVIPPYGGDTVWSNTAAAYLDLP 119 I ++S G +A++WHTDVTF YP SVLR V +P YGG T+W+NTAAAY +LP Sbjct: 81 APIITPINSEFG--KANRWHTDVTFAANYPAASVLRAVSLPSYGGSTLWANTAAAYAELP 138 Query: 120 APLRKLADELWAIHSNAYDYAVKSRATDADRKHFDEVFTGTIYETEHPVVRVHPETGEHT 179 PL+ L + LWA+H+N YDY V ++ A ++ F +VF + TEHPVVRVHPETGE T Sbjct: 139 EPLKCLTENLWALHTNRYDY-VTTKPLTAAQRAFRQVFEKPDFRTEHPVVRVHPETGERT 197 Query: 180 LVLGNFVQRFVGLPKYDGQKLFDLFQSHITAPENTVRWSWRAGDVAIWDNRATQHYAVND 239 L+ G+FV+ FVGL ++ + LF++ Q IT PENT+RW+W GDVAIWDNRATQH A++D Sbjct: 198 LLAGDFVRSFVGLDSHESRVLFEVLQRRITMPENTIRWNWAPGDVAIWDNRATQHRAIDD 257 Query: 240 YGDQHRVVRRATIDGEVPVSVDGRHSVTRIKSPKP 274 Y DQHR++ R T+ G+VPV V G+ S R+ S P Sbjct: 258 YDDQHRLMHRVTLMGDVPVDVYGQAS--RVISGAP 290 >PA3935 [Q] COG2175 Probable taurine catabolism dioxygenase Pae Pseudomonas aeruginosa Length = 277 Score = 181 bits (459), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 108/248 (43%), Positives = 137/248 (55%), Gaps = 5/248 (2%) Query: 13 RAINQVLLEHKVIFFRDQEHLDDAEQERFAVRLGKLVPHPTIGPSKGTSSILELDSGRGG 72 RAI Q LLEH+V+FFRDQ L+ Q RFA R G L HP ++ LD+ Sbjct: 31 RAIEQALLEHQVLFFRDQS-LEPRSQARFAARFGDLHIHPIYPSVPEQPEVIVLDTAVTD 89 Query: 73 GRADQ-WHTDVTFVDAYPKISVLRGVVIPPYGGDTVWSNTAAAYLDLPAPLRKLADELWA 131 R + WHTDVTF++ +VL +PPYGGDT+W+++ AAY L APLR+L D L A Sbjct: 90 VRDNAIWHTDVTFLETPALGAVLAAKQLPPYGGDTLWASSTAAYEALSAPLRRLLDGLTA 149 Query: 132 IHSNAYDYA-VKSRATDADRKHFDEVFTGTIYETEHPVVRVHPETGEHTLVLGN-FVQRF 189 H + + T+AD +E + HPVVR HP TG L + + F R Sbjct: 150 THDIGKSFPRERFGVTEADLARLEEARLKNPPRS-HPVVRTHPVTGRKGLFVSDGFTTRI 208 Query: 190 VGLPKYDGQKLFDLFQSHITAPENTVRWSWRAGDVAIWDNRATQHYAVNDYGDQHRVVRR 249 L + L +H T PE TVRW W+ DVA WDNR TQHYAV+DY Q RV+ R Sbjct: 209 NELEPAESDALLKFLFAHATRPEFTVRWRWQENDVAFWDNRVTQHYAVDDYRPQRRVMHR 268 Query: 250 ATIDGEVP 257 ATI G+ P Sbjct: 269 ATILGDKP 276