BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0193.0059.p (547 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA2648 [P] COG3119 Arylsulfatase A and related enzymes Mac Metha... 655 0.0 SMb20915 [P] COG3119 Arylsulfatase A and related enzymes Sme Sin... 579 e-165 mll5471 [P] COG3119 Arylsulfatase A and related enzymes Mlo Meso... 577 e-164 SMa0943 [P] COG3119 Arylsulfatase A and related enzymes Sme Sino... 576 e-164 SMa1683 [P] COG3119 Arylsulfatase A and related enzymes Sme Sino... 229 1e-59 >MA2648 [P] COG3119 Arylsulfatase A and related enzymes Mac Methanosarcina acetivorans str.C2A Length = 535 Score = 655 bits (1691), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/540 (59%), Positives = 398/540 (73%), Gaps = 13/540 (2%) Query: 3 DEAELRNNGAAKLNGNSRGSLLRSLFAAALVATSLSPLARSPALAQQPGTAKPNILVIFG 62 DE LR G ++N G L++L A + S+ L + KPNILVI+G Sbjct: 4 DETTLRK-GQIRINEFKLGYRLKALIQA--LNQSIWGLRMT--------EKKPNILVIWG 52 Query: 63 DDIGQSNISAYTRGVVGYKTPNIDRIANEGMMFTDYYAENSCTAGRSTFITGQACLRTGL 122 DDIG SN+S Y+ G++GY+TPNIDRIANEGM FTD Y E SCTAGR+ FITGQ+ RTGL Sbjct: 53 DDIGISNLSCYSDGLMGYRTPNIDRIANEGMRFTDSYGEQSCTAGRAAFITGQSVFRTGL 112 Query: 123 CKVGIPGATVGLQDRDVTIAQALKPLGYATGQFGKNHLGDRDEYLPVKHGFDEFFGNLYH 182 KVG+PGA +GLQ D TIA+ LKPLGYATGQFGKNH GD DE+LP HGFDEFFGNLYH Sbjct: 113 SKVGMPGAKIGLQPEDPTIAELLKPLGYATGQFGKNHFGDLDEFLPTNHGFDEFFGNLYH 172 Query: 183 LNAEEEPERPYYP--KNDTAFTKSNTPRGVLKASADGKIEDTGPLNRKRMETVDDETTAA 240 LNAEEEPE+ YP K+ F K+ PRGV+++ ADG+IEDTGPL +KRME D E A Sbjct: 173 LNAEEEPEKRDYPPEKDFPNFRKNYGPRGVIRSYADGRIEDTGPLTKKRMEEADQEFLDA 232 Query: 241 AIDFMQRQAKANKPFFTWMNTTRMHAFTHVRASMQGQSGMPGNEYADGMIEHDGDVGKLL 300 IDF++RQ +A KPFF W NTTRMH TH+ ++GQSG + Y D MIEHD +G LL Sbjct: 233 TIDFIKRQHEAEKPFFVWFNTTRMHFRTHIPDRIRGQSGRWQSAYHDAMIEHDRQIGVLL 292 Query: 301 KALDDLGIANNTIVVYTTDNGPNQWSWPDAATTPFRSEKDTNWEGAFRVPAMVRWPGHIK 360 LD++GIA++TIV+Y+TDNGP+ SWPDAA TPFR+EKD+ WEGAFRVP ++RWPG I Sbjct: 293 DLLDEIGIADDTIVLYSTDNGPHMNSWPDAAMTPFRNEKDSCWEGAFRVPELIRWPGKIP 352 Query: 361 AGEVSNEMMSGLDWFPTLLAAAGESDVKDKLLKGSDIGGKSFKVHLDGYNQLPYLTGQQP 420 AG+VSNE +S LDW PTLLAAA E D+K+KL KG G K+FKVHLDGYN LPYLTG++ Sbjct: 353 AGKVSNEFVSHLDWLPTLLAAAEEPDIKEKLKKGHKAGDKTFKVHLDGYNLLPYLTGKEK 412 Query: 421 KSARNDFYYFNDDGQVVAYRYNDWKIVFCEQREPGGFVVWANPFTCLRAPKVFNLRMDPF 480 KS R +F+YF+D G ++A RY++WK+VF EQR G +VWA PF LR PK+FNLR DP+ Sbjct: 413 KSPRTEFFYFSDGGDLMAIRYDNWKLVFLEQRATGTLLVWAEPFVPLRVPKIFNLRTDPY 472 Query: 481 ERADVVSDQYYDWLAKNAYLIQYGVWRVAPFLQTFKEFPPSQRSASFSIDQMVDALMKTL 540 ERAD S+ YYDWL +A+L+ V FL TFKEFPP Q++ASF++DQ+++ L++ + Sbjct: 473 ERADRTSNTYYDWLLDHAFLVVPAQGVVGDFLATFKEFPPRQKAASFTVDQVMEKLLQGI 532 >SMb20915 [P] COG3119 Arylsulfatase A and related enzymes Sme Sinorhizobium meliloti Length = 537 Score = 579 bits (1492), Expect = e-165, Method: Compositional matrix adjust. Identities = 304/540 (56%), Positives = 377/540 (69%), Gaps = 12/540 (2%) Query: 1 MSDEAELRNNGAAKLNGNSRGSLLRSLFAAALVATSLSPLARSPALAQQPGTA----KPN 56 M+DE E + + G SR LL + A+ AT+++ +PA AQ T KPN Sbjct: 1 MADELEGVSPKETR-QGLSRRDLL--VAGTAMAATAVTLAGPTPAKAQAASTGGSGRKPN 57 Query: 57 ILVIFGDDIGQSNISAYTRGVVGYKTPNIDRIANEGMMFTDYYAENSCTAGRSTFITGQA 116 IL+I GDDIG N S Y RG++GY+TPNIDRI NEG MFTD+Y E SCTAGR+ FITGQ+ Sbjct: 58 ILMIMGDDIGWFNPSIYHRGMMGYRTPNIDRIGNEGAMFTDWYGEQSCTAGRAAFITGQS 117 Query: 117 CLRTGLCKVGIPGATVGLQDRDVTIAQALKPLGYATGQFGKNHLGDRDEYLPVKHGFDEF 176 +RTGL KVG+PGA +G+Q D T+A+ LK LGYATGQFGKNHLGD+DE+LP HGFDEF Sbjct: 118 PIRTGLTKVGLPGADIGIQPEDATVAELLKSLGYATGQFGKNHLGDKDEFLPTAHGFDEF 177 Query: 177 FGNLYHLNAEEEPERPYYPKNDTAFTKSNTPRGVLKASADGKIEDTGPLNRKRMETVDDE 236 FGNLYHLNAEEEPE P YP+ D AF K PRGV+KA+ADGKIEDTGPL+ KRMETVD E Sbjct: 178 FGNLYHLNAEEEPENPDYPQ-DPAFRKRFGPRGVIKATADGKIEDTGPLSVKRMETVDQE 236 Query: 237 TTAAAIDFMQRQAKANKPFFTWMNTTRMHAFTHVRASMQGQSGMPGNEYADGMIEHDGDV 296 AA+DF+ R+AK + P+F + N+TRMH TH++ G++G+ Y DGM+EHDG V Sbjct: 237 FLEAALDFIDRKAKGDAPWFCYFNSTRMHVNTHLKPDSAGKTGL--GVYPDGMVEHDGHV 294 Query: 297 GKLLKALDDLGIANNTIVVYTTDNGPNQWSWPDAATTPFRSEKDTNWEGAFRVPAMVRWP 356 G+LLK LDDLG+ NTIVVYT+DNG +WPD TPFR EK TNWEG FRVP +RWP Sbjct: 295 GELLKKLDDLGLTENTIVVYTSDNGAEVMTWPDGGNTPFRGEKATNWEGGFRVPMCIRWP 354 Query: 357 GHIKAGEVSNEMMSGLDWFPTLLAAAGESDVKDKLLKGSDIGGKSFKVHLDGYNQLPYLT 416 G IK G + NE S D PT AAAGE D+ K L G G K+FKVHLDGYN +P+L+ Sbjct: 355 GVIKPGTIHNEPFSHYDLIPTFCAAAGEPDIVAKCLTGYAAGAKTFKVHLDGYNLMPFLS 414 Query: 417 GQQPKSARNDFYYFNDDGQVVAYRYNDWKIVFCEQREPGGFVVWANPFTCLRAPKVFNLR 476 G + R DF Y+NDDG++VA R +WK+VF Q G VW PFT LRAP +FNLR Sbjct: 415 GSSNDAPRRDFLYWNDDGELVAVRVQNWKVVFKSQDHE-GIGVWRQPFTELRAPLLFNLR 473 Query: 477 MDPFERADVVSDQYYDWLAKNAYLIQYGVWRVAPFLQTFKEFPPSQRSASFSIDQMVDAL 536 DPFER D S +Y W ++++ VA +L++FKEFP Q+ ASF++DQ+++ L Sbjct: 474 SDPFERGD-TSMEYEKWFFDRSFVVVPSQAVVAKWLESFKEFPIRQKPASFNLDQVMEKL 532 >mll5471 [P] COG3119 Arylsulfatase A and related enzymes Mlo Mesorhizobium loti Length = 557 Score = 577 bits (1486), Expect = e-164, Method: Compositional matrix adjust. Identities = 286/502 (56%), Positives = 357/502 (71%), Gaps = 21/502 (4%) Query: 53 AKPNILVIFGDDIGQSNISAYTRGVVGYKTPNIDRIANEGMMFTDYYAENSCTAGRSTFI 112 +KPNILVIFGDDIG N SAY RG++GY+TPNIDRIA EG +FTD YA+ SCTAGR+ FI Sbjct: 54 SKPNILVIFGDDIGYWNTSAYNRGMMGYRTPNIDRIAREGAIFTDLYAQQSCTAGRAAFI 113 Query: 113 TGQACLRTGLCKVGIPGATVGLQDRDVTIAQALKPLGYATGQFGKNHLGDRDEYLPVKHG 172 TGQ+C RTGL KVG+P A GL +D T+A+ LKP GYATGQFGKNH+GDR+E+LP HG Sbjct: 114 TGQSCFRTGLLKVGLPAAPEGLSGKDPTLAELLKPQGYATGQFGKNHVGDRNEFLPTVHG 173 Query: 173 FDEFFGNLYHLNAEEEPERPYYPKNDTAFTKSNTPRGVLKASA----------------D 216 FDEFFGNLYHLNAEEEPE YPKN F PRGVLK +A Sbjct: 174 FDEFFGNLYHLNAEEEPENVDYPKN-PEFHAKFGPRGVLKCTATETDDPTEDPRFGRVGK 232 Query: 217 GKIEDTGPLNRKRMETVDDETTAAAIDFMQRQAKANKPFFTWMNTTRMHAFTHVRASMQG 276 KIEDTGPL +KRMETVD+E AA DF+ RQ KA+KPFF W N+TRMH TH++ + +G Sbjct: 233 QKIEDTGPLTKKRMETVDEEFLGAAKDFIDRQHKASKPFFCWFNSTRMHINTHLKPASEG 292 Query: 277 QSGMPGNEYADGMIEHDGDVGKLLKALDDLGIANNTIVVYTTDNGPNQWSWPDAATTPFR 336 ++G+ G E ADGM+E DG VG+LL+ LDDLGIA+NTIV++TTDNG +SWPD TTPF Sbjct: 293 KTGL-GME-ADGMVELDGMVGQLLQQLDDLGIADNTIVLWTTDNGAEVFSWPDGGTTPFH 350 Query: 337 SEKDTNWEGAFRVPAMVRWPGHIKAGEVSNEMMSGLDWFPTLLAAAGESDVKDKLLKGSD 396 EK+T+WEG +RVP M+RWPG +K G N+++S DW PTL+AAAGE +VK+KLL G + Sbjct: 351 GEKNTSWEGGYRVPGMIRWPGVVKPGTEINDIVSHEDWVPTLVAAAGEPNVKEKLLTGYE 410 Query: 397 IGGKSFKVHLDGYNQLPYLTGQQPKSARNDFYYFNDDGQVVAYRYNDWKIVFCEQREPGG 456 GK+FKVHLDGY+Q L G P R +F+Y+ D+G + A+RY+ WKI+F EQR G Sbjct: 411 AAGKTFKVHLDGYDQHDLLAGTGP-DPRKEFFYWTDEGNLAAFRYDRWKILFLEQRAE-G 468 Query: 457 FVVWANPFTCLRAPKVFNLRMDPFERADVVSDQYYDWLAKNAYLIQYGVWRVAPFLQTFK 516 F VW PF LR PK+F++R DPFERA + +Y W Y++ V LQ+F Sbjct: 469 FDVWEEPFVALRVPKIFDVRADPFERAQREAAEYVRWRFDRTYVLMPAQAFVGQHLQSFV 528 Query: 517 EFPPSQRSASFSIDQMVDALMK 538 FPP Q+ SFS+ Q+++ L + Sbjct: 529 AFPPRQKPGSFSLGQVLEKLQE 550 >SMa0943 [P] COG3119 Arylsulfatase A and related enzymes Sme Sinorhizobium meliloti Length = 545 Score = 576 bits (1484), Expect = e-164, Method: Compositional matrix adjust. Identities = 291/526 (55%), Positives = 362/526 (68%), Gaps = 22/526 (4%) Query: 29 AAALVATSLSPLARSPALAQQPGTAKPNILVIFGDDIGQSNISAYTRGVVGYKTPNIDRI 88 + L T+L L + A AQ G KPNILVIFGDDIG N SAY RG +GY+TPNIDRI Sbjct: 22 GSLLAVTALGSLTGAGAKAQTAGK-KPNILVIFGDDIGWWNTSAYNRGQMGYQTPNIDRI 80 Query: 89 ANEGMMFTDYYAENSCTAGRSTFITGQACLRTGLCKVGIPGATVGLQDRDVTIAQALKPL 148 A+EG +FTD YA+ SCTAGR+ FITGQ+C RTGL KVG+PGA GL D+D T+A+ LKP Sbjct: 81 ADEGAIFTDLYAQQSCTAGRAAFITGQSCFRTGLLKVGLPGAKEGLSDKDPTLAELLKPH 140 Query: 149 GYATGQFGKNHLGDRDEYLPVKHGFDEFFGNLYHLNAEEEPERPYYPKNDTAFTKSNTPR 208 GYATGQFGKNHLGDR+E+LP HGFDEFFGNLYHLNAEEEPE P YPK D F PR Sbjct: 141 GYATGQFGKNHLGDRNEFLPTVHGFDEFFGNLYHLNAEEEPENPDYPK-DPQFRAKFGPR 199 Query: 209 GVLKASADG----------------KIEDTGPLNRKRMETVDDETTAAAIDFMQRQAKAN 252 GVL+ A KIEDTGPL+++RMETVD E AA++F+ + KA Sbjct: 200 GVLRCVASDTDDPTEDPRFGRVGKQKIEDTGPLDKRRMETVDGEFLGAAMNFIDKNQKAG 259 Query: 253 KPFFTWMNTTRMHAFTHVRASMQGQSGMPGNEYADGMIEHDGDVGKLLKALDDLGIANNT 312 KPFF W N TRMH +TH++ QG++G+ ADGM E DG VG+LLK LDDLGIA+NT Sbjct: 260 KPFFCWFNATRMHIYTHLKPESQGKTGL--GLVADGMTEFDGMVGQLLKQLDDLGIADNT 317 Query: 313 IVVYTTDNGPNQWSWPDAATTPFRSEKDTNWEGAFRVPAMVRWPGHIKAGEVSNEMMSGL 372 IV++TTDNG +SWPD +TPF EK+TNWEG +RVP ++RWPG IK G N+++S Sbjct: 318 IVLFTTDNGAEVFSWPDGGSTPFHGEKNTNWEGGYRVPGVMRWPGVIKPGTEINDIVSHE 377 Query: 373 DWFPTLLAAAGESDVKDKLLKGSDIGGKSFKVHLDGYNQLPYLTGQQPKSARNDFYYFND 432 DW PT +AAAGE DVK KLL G + GK+FKVHLDGYNQ L G P S+R +++Y+ D Sbjct: 378 DWVPTFVAAAGEPDVKQKLLTGYEAAGKTFKVHLDGYNQRELLAGSGP-SSRKEYFYWTD 436 Query: 433 DGQVVAYRYNDWKIVFCEQREPGGFVVWANPFTCLRAPKVFNLRMDPFERADVVSDQYYD 492 DG + A RY+ WK+VF EQR G VW +P LR PK+ +LR DPFE A V+ Y Sbjct: 437 DGNLAALRYDRWKLVFMEQRAE-GLDVWQDPLITLRFPKLIDLRADPFEIAQHVAGDYDR 495 Query: 493 WLAKNAYLIQYGVWRVAPFLQTFKEFPPSQRSASFSIDQMVDALMK 538 W ++A+ + V LQT+ +FPP Q SF++++++ L + Sbjct: 496 WRVEHAFALVPAQAFVVRHLQTYVDFPPRQTPGSFALNEVMAKLQE 541 >SMa1683 [P] COG3119 Arylsulfatase A and related enzymes Sme Sinorhizobium meliloti Length = 555 Score = 229 bits (584), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 181/562 (32%), Positives = 272/562 (48%), Gaps = 62/562 (11%) Query: 23 LLRSLFAAALVATSLSPLARSPALAQQPGTAKPNILVIFGDDIGQSNISAYTRGVVG-YK 81 L+RS+ A + +T L A SP Q KPNIL I DD G ++ Y G Sbjct: 5 LMRSV-GAFVASTVLWCTASSPQ--AQEARPKPNILFIVSDDTGYGDLGPYGGGEGRGMP 61 Query: 82 TPNIDRIANEGMMFTDYYAENSCTAGRSTFITGQACLRTGLCKVGIPGATVGLQDRDVTI 141 TPNIDR+A+EGM F +YA+ SCT GR+ TG+ R+G+ V G GL + T+ Sbjct: 62 TPNIDRLADEGMTFFSFYAQPSCTPGRAAMQTGRIPNRSGMTTVAFQGQGGGLPAAEWTL 121 Query: 142 AQALKPLGYATGQFGKNHLGDRDEYLPVKHGFDEF-FGNLYHLNAEEEPERPYYPKND-- 198 A LK GY T GK HLG+ D LP G+DE + LYHLNA + ++P D Sbjct: 122 ASVLKRGGYQTYFTGKWHLGEADYALPNAQGYDEMKYVGLYHLNAYTYADPTWFPDMDAE 181 Query: 199 TAFTKSNTPRGVLKASADGKIEDTGPLNRKRMET--------------VDDETTAAAIDF 244 T +G L A G++ + +N + ++T D AAI+F Sbjct: 182 TRALFQKVTKGSLSGKAGGEVTEDFKINGQYVDTPVIDGKPGVVGIPFFDGYVEKAAIEF 241 Query: 245 MQRQAKA-NKPFFTWMNTTRMHAFTHVRASMQGQSGMPGNEYADGMIEHDGDVGKLLKAL 303 + AK ++PFF +N ++H Q +S + ++YAD ++E D +G++L L Sbjct: 242 LDAAAKKPDQPFFINVNFMKVHQPNLPAPEFQHKS-LSKSKYADSVVELDTRIGRILDKL 300 Query: 304 DDLGIANNTIVVYTTDNGPNQWSWPDAATTPFRSEKDTNWEGAFRVPAMVRWPGHIKAGE 363 + G+ NT+V YTTDNG Q +PDA TPFR K T EG RVPA+ WPG I+ G Sbjct: 301 RETGMDKNTLVFYTTDNGAWQDVYPDAGYTPFRGTKGTVREGGNRVPAIAFWPGKIQPGS 360 Query: 364 VSNEMMSGLDWFPTLLAAAG----ESDVKDKLLKGSDIGGKSFKVHLDGYNQLPYLTGQQ 419 S++++ GLD T +AAG + D +DK + D Y+ P L G Sbjct: 361 RSHDVVGGLDLMATFASAAGVPLPDRDREDK------------PIIFDSYDMTPVLLGTG 408 Query: 420 PKSARNDFYYFNDDGQVVAYRYNDWKIVFCEQ----REPGGFVV-----W--ANPFTCLR 468 + +N FY+ ++ A R +K VF + + GG V W A + + Sbjct: 409 ESARKNWFYFTENELTPGAARVGHYKAVFNLRGDNGQATGGLAVDTNLGWKGAQSYVAI- 467 Query: 469 APKVFNLRMDPFERADVVSDQYYDWLAKNAYLIQYGVWRVAPFLQTFKEFPPSQRSA--- 525 P+VF+L DP ER DV + Y ++ + + + ++T+ E+PP + + Sbjct: 468 VPQVFDLWQDPQERYDVFMNNY----TEHTWSLVSISAAIKDLMKTYVEYPPRKLQSMGY 523 Query: 526 ----SFSIDQMVDALMKTLDKQ 543 S QM+ ++ + +K+ Sbjct: 524 DGPIELSKYQMLQSVREQFEKE 545