BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0192.0124.p (522 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl781 [GEPR] COG0477 Permeases of the major facilitator superfa... 328 2e-89 RP157 [GEPR] COG0477 Permeases of the major facilitator superfam... 327 3e-89 mlr4819 [GEPR] COG0477 Permeases of the major facilitator superf... 325 2e-88 RC0200 [GEPR] COG0477 Permeases of the major facilitator superfa... 325 2e-88 BMEII1119 [GEPR] COG0477 Permeases of the major facilitator supe... 311 2e-84 >AGl781 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 527 Score = 328 bits (841), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 177/423 (41%), Positives = 253/423 (59%), Gaps = 9/423 (2%) Query: 20 FLLMCFGMFMAILDIQVVATSLPTIQRALAISPAAMSWIQTAYLIAEVIAIPLTGLFTHA 79 F M FGMFM+ILDIQ+V+ SL IQ L ++W+QT+YLIAEVI IPL+G Sbjct: 27 FFAMVFGMFMSILDIQIVSASLAEIQAGLGAGSDEIAWVQTSYLIAEVIMIPLSGTLARI 86 Query: 80 LSLRWLFALAVSLFTVASVGCALSGGFAALLAFRVLQGFSGGVLIPAVFSAVFTLFPARL 139 LS R LFA + FT++S CA + ++ +R +QGF GG +IP+VF+A FT+FP Sbjct: 87 LSTRVLFATCAAGFTLSSALCATATNIDQMIVYRAIQGFIGGGMIPSVFAAAFTIFPPSK 146 Query: 140 HPVATTIGGVVAVLAPTVGPVVGGWITQTWSWPWLFLVNLVPGAVAAVVTPLLLPKEGVQ 199 V + I G+VA LAPT+GP VGG+++ +SW WLFLVN++PG + ++T L+ + + Sbjct: 147 RSVVSPIIGLVATLAPTIGPTVGGYLSNAFSWHWLFLVNIIPGIIVTILTWSLIDFDKPE 206 Query: 200 LRAFARLDKWSLVLLAATLASFMIGLKEAPQRGWAAMPCLGLLIGSIT---GMALLIRRT 256 + + D W L+ +A L S L+E + W ++IGS+ G + R Sbjct: 207 TSLWKKFDWWGLISMAVFLGSLEYVLEEGNNKDW--FNDEHIVIGSVAMVIGAVVFFWRA 264 Query: 257 LRAAYPIAQLTLFKRRPFAIGCGLSFCLGIGLYGSTYLMPVFLGFVRRHDAFEIGTVMLV 316 + +P+ + F R F+IG SF +GIGLYG TYL P++LG VR +DA IG M V Sbjct: 265 FKVDFPVVDIRAFADRNFSIGSLFSFVMGIGLYGLTYLYPLYLGRVRGYDALMIGETMFV 324 Query: 317 TGVAQLVAAPLAAILESRIGARRLTGAGFALFALGLGWSAIQPRTADFAEMFWPQVVRGV 376 +G+A AP+A + +++ R + GF F G DF E+ PQ++RG Sbjct: 325 SGLAMFFTAPIAGKVSTKLDPRVMMAIGFISFGCGTWIMTYVTTDWDFYELLIPQILRGF 384 Query: 377 AIMFCLLPPTRIALGALPEAEIADASGLFNLMRNLGGAIGIALIDTILYARSPIYGEDFR 436 +M C++P IALG LP A I +ASGLFNL RNLGGA+G+A+I+T+L R+ +D Sbjct: 385 GLMMCMVPINNIALGTLPPARIRNASGLFNLTRNLGGAVGLAVINTLLSQRT----DDHY 440 Query: 437 VRL 439 VRL Sbjct: 441 VRL 443 >RP157 [GEPR] COG0477 Permeases of the major facilitator superfamily Rpr Rickettsia prowazekii Length = 519 Score = 327 bits (839), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 190/510 (37%), Positives = 283/510 (55%), Gaps = 7/510 (1%) Query: 4 GADHRTDGPSAATWAGFLLMCFGMFMAILDIQVVATSLPTIQRALAISPAAMSWIQTAYL 63 D +T S F M GMFM++LDIQ+VA+SL I LA S +SW+QT+YL Sbjct: 3 NNDLKTPPLSKKQLLAFFGMIVGMFMSVLDIQIVASSLSVIAAGLAASSDELSWVQTSYL 62 Query: 64 IAEVIAIPLTGLFTHALSLRWLFALAVSLFTVASVGCALSGGFAALLAFRVLQGFSGGVL 123 IAEVI IP+TG LS R + +A FT+ SV C+L+ +++ FR LQGF GG + Sbjct: 63 IAEVIIIPITGFLARLLSTRICYFIAALGFTIMSVLCSLANNIESMIIFRALQGFFGGAM 122 Query: 124 IPAVFSAVFTLFPARLHPVATTIGGVVAVLAPTVGPVVGGWITQTWSWPWLFLVNLVPGA 183 IP VFS V+ +FPA P T + G+V +APT+GP +GG+IT+ SW ++FL+N++PG Sbjct: 123 IPLVFSTVYIIFPASQRPTVTILIGLVVTVAPTLGPTLGGYITEILSWHFMFLLNVIPGI 182 Query: 184 VAAVVTPLLLPKEGVQLRAFARLDKWSLVLLAATLASFMIGLKEAPQRGWAAMPCLGLLI 243 V L + + + D ++L++ TL L+E + GW + L Sbjct: 183 FVCTVVFLYVNFDKPNYQLLKNFDFLGILLMSLTLGLLQYVLEEGNKEGWLDDNLILFL- 241 Query: 244 GSIT---GMALLIRRTLRAAYPIAQLTLFKRRPFAIGCGLSFCLGIGLYGSTYLMPVFLG 300 SIT G LLI R L PI L F + F GC SF +GIGLYG+ Y++P+FL Sbjct: 242 -SITVALGFILLIIRELTFINPILDLKTFLYKDFTFGCIYSFVMGIGLYGAVYILPLFLF 300 Query: 301 FVRRHDAFEIGTVMLVTGVAQLVAAPLAA-ILESRIGARRLTGAGFALFALGLGWSAIQP 359 + +D +IG M+VTGVAQ ++APLA +L I R + G FALG ++ Sbjct: 301 TIAEYDTLQIGATMMVTGVAQFLSAPLAGRMLGLGIDLRMMLTIGLGGFALGCHLNSCLT 360 Query: 360 RTADFAEMFWPQVVRGVAIMFCLLPPTRIALGALPEAEIADASGLFNLMRNLGGAIGIAL 419 + FA PQ VRG ++MFC +P IALG +P+ ++ +ASGL+NL RNLGGA+G+A+ Sbjct: 361 PDSKFAAFILPQFVRGFSLMFCFIPTNNIALGNMPKEKVGNASGLYNLTRNLGGAVGLAI 420 Query: 420 IDTILYARSPIYGEDFRVRLLAGDVTAAQAIGLDPKLLIDRPPGLPDDATVAFIRPLVER 479 I TIL + I+ + + + A + +LL + P+ + + + Sbjct: 421 ISTILSNDTKIFMQYLSENISYTSIIALTRLDSYTELLSGKILN-PEQGSYLLLANKLNN 479 Query: 480 ASLALTVNEAWAMLACVAIVGLLLVPFASD 509 + + +N + M+ + + +LL+PF S+ Sbjct: 480 DAFVIAINNIFNMIGLLFVFIMLLIPFTSN 509 >mlr4819 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 531 Score = 325 bits (833), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 204/492 (41%), Positives = 282/492 (57%), Gaps = 14/492 (2%) Query: 20 FLLMCFGMFMAILDIQVVATSLPTIQRALAISPAAMSWIQTAYLIAEVIAIPLTGLFTHA 79 FL M FGMFMAILDIQ+V+ SL IQ L+ S + W+QTAYLIAEV+ IPL+G + Sbjct: 29 FLAMVFGMFMAILDIQIVSASLAEIQAGLSASSDEIPWVQTAYLIAEVVMIPLSGFLSRM 88 Query: 80 LSLRWLFALAVSLFTVASVGCALSGGFAALLAFRVLQGFSGGVLIPAVFSAVFTLFPARL 139 LS R LF +A + FT AS A + ++ +R +QGF GG +IP+VF+A FT+FP Sbjct: 89 LSTRVLFTIAAAGFTAASALAATATNIDQMIVYRAVQGFIGGGMIPSVFAAAFTIFPPSK 148 Query: 140 HPVATTIGGVVAVLAPTVGPVVGGWITQTWSWPWLFLVNLVPGAVAAVVTPLLLPKEGVQ 199 V + + G+VA LAPT+GP VGG+I+ +SW WLFLVN+VPG + A L+ + Sbjct: 149 RAVVSPMIGLVATLAPTIGPTVGGYISHAFSWHWLFLVNVVPGILVATAAWSLIDFDKPN 208 Query: 200 LRAFARLDKWSLVLLAATLASFMIGLKEAPQRGWAAMPCLGLLIGSIT---GMALLIRRT 256 L+ F + D W L +AA L L+E P W + G+ I +I G + R Sbjct: 209 LKLFNKFDWWGLAGMAAFLGCMEYVLEEGPNNDW--LQDQGVFICAIVMTIGAVIFFWRV 266 Query: 257 LRAAYPIAQLTLFKRRPFAIGCGLSFCLGIGLYGSTYLMPVFLGFVRRHDAFEIGTVMLV 316 A PI L F FA G SF +GIGLYG TYL PVFLG +R +D+ IG + V Sbjct: 267 FTAEEPIVDLRAFSNVNFAFGSLFSFVIGIGLYGLTYLYPVFLGRIRGYDSMMIGEALFV 326 Query: 317 TGVAQLVAAPLAAILESRIGARRLTGAGFALFALGLGWSAIQPRTADFAEMFWPQVVRGV 376 +G+A V AP++ L S+I R + GF FA G W DF E+ PQ++RG Sbjct: 327 SGLAMFVTAPISGFLSSKIDLRLMMMIGFFGFATGTWWMTHLTADWDFYELLIPQILRGC 386 Query: 377 AIMFCLLPPTRIALGALPEAEIADASGLFNLMRNLGGAIGIALIDTILYARSPIYGEDFR 436 ++M C++P IALG LP + +ASGLFNL RNLGGA+G+ALI+T+L R+ + Sbjct: 387 SMMLCMVPINNIALGTLPPDRLKNASGLFNLTRNLGGAVGLALINTVLINRNAFHYARLG 446 Query: 437 VRLLAGDVTAAQAIGLDPKLLIDRPPGLPDDATVAFIRPLVERASLALTVNEAWAMLACV 496 + G AAQ + L ++ GL DA A I + L+ V++ A+L+ + Sbjct: 447 EHVQWGS-AAAQTKLQNMTLNFEQTSGL--DAAGAAI------SKLSGMVHQQAALLSFM 497 Query: 497 AIVGLLLVPFAS 508 + +L V FA+ Sbjct: 498 DVFYMLTVLFAT 509 >RC0200 [GEPR] COG0477 Permeases of the major facilitator superfamily Rco Rickettsia conorii Length = 519 Score = 325 bits (833), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 187/499 (37%), Positives = 281/499 (56%), Gaps = 3/499 (0%) Query: 13 SAATWAGFLLMCFGMFMAILDIQVVATSLPTIQRALAISPAAMSWIQTAYLIAEVIAIPL 72 S F M GMFM++LDIQ+VA+SL I LA S +SW+QT+YLIAEVI IP+ Sbjct: 12 SKKQLFAFFGMVVGMFMSVLDIQIVASSLSVIAAGLAASSDELSWVQTSYLIAEVIIIPI 71 Query: 73 TGLFTHALSLRWLFALAVSLFTVASVGCALSGGFAALLAFRVLQGFSGGVLIPAVFSAVF 132 TG L+ R + +A FTV S+ C+L+ +++ FR LQGF GG +IP VFS VF Sbjct: 72 TGFLARLLTTRISYFIAALGFTVMSILCSLATNIESMIIFRALQGFFGGAMIPTVFSTVF 131 Query: 133 TLFPARLHPVATTIGGVVAVLAPTVGPVVGGWITQTWSWPWLFLVNLVPGAVAAVVTPLL 192 LFPA P+ T + G+V +APT+GP +GG+IT+ SW ++FL+N++PG V L Sbjct: 132 ILFPASQRPIVTILIGLVVTVAPTLGPTLGGYITEILSWHFMFLLNVIPGIFVCTVVFLY 191 Query: 193 LPKEGVQLRAFARLDKWSLVLLAATLASFMIGLKEAPQRGWAAMP-CLGLLIGSITGMAL 251 + + D ++L+A TL L+E ++GW L L I + G L Sbjct: 192 GDFDKPNYKLLKNFDFLGILLMALTLGLLQYVLEEGNKKGWLEDNLILFLSITVVLGFIL 251 Query: 252 LIRRTLRAAYPIAQLTLFKRRPFAIGCGLSFCLGIGLYGSTYLMPVFLGFVRRHDAFEIG 311 LI R L PI L F + F GC SF +GIGLYG+ Y++P+FL + +D +IG Sbjct: 252 LIIRELTCINPILDLKTFLYKDFTFGCLYSFVMGIGLYGTVYILPLFLFTIAGYDTLQIG 311 Query: 312 TVMLVTGVAQLVAAPLAA-ILESRIGARRLTGAGFALFALGLGWSAIQPRTADFAEMFWP 370 M+VTG AQ ++APLA +L + R + G FALG ++ + FA P Sbjct: 312 ATMMVTGGAQFLSAPLAGRMLGLGVDLRLMLIIGLGGFALGCHLNSFLTPDSKFAAFVLP 371 Query: 371 QVVRGVAIMFCLLPPTRIALGALPEAEIADASGLFNLMRNLGGAIGIALIDTILYARSPI 430 Q VRG+++MFC +P IALG +P+ + +ASGL+NL RNLGGA+G+A+I TIL + Sbjct: 372 QFVRGLSLMFCFIPTNNIALGNMPKERVGNASGLYNLTRNLGGAVGLAIISTILTNDTKT 431 Query: 431 YGEDFRVRLLAGDVTAAQAIGLDPKLLIDRPPGLPDDATVAFIRPLVERASLALTVNEAW 490 + + + + + A + + +LL + P+ A+ + + + + +N + Sbjct: 432 FMQYLSENISSTSIMALEQLDSYTELLSGKVLN-PEKASYLLLANKLNHDAFVIAINNIF 490 Query: 491 AMLACVAIVGLLLVPFASD 509 M+ + + +LL+PF S+ Sbjct: 491 NMIGLLFVFIMLLIPFTSN 509 >BMEII1119 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 525 Score = 311 bits (798), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 177/447 (39%), Positives = 255/447 (57%), Gaps = 8/447 (1%) Query: 5 ADHRTDGPSAATWAGFLLMCFGMFMAILDIQVVATSLPTIQRALAISPAAMSWIQTAYLI 64 AD R D P GF+ M FGMFMAILDIQ+V+ SL IQ L S +SW+Q +YLI Sbjct: 16 ADDRID-PKKTI--GFMAMVFGMFMAILDIQIVSASLSEIQAGLGASTDEISWVQISYLI 72 Query: 65 AEVIAIPLTGLFTHALSLRWLFALAVSLFTVASVGCALSGGFAALLAFRVLQGFSGGVLI 124 AEVI IPL+G LS R LF ++ + FT+AS+ CA + ++ +R +QGF GG +I Sbjct: 73 AEVIMIPLSGFLGRLLSTRVLFTISATGFTLASMLCATATNIEQMIVYRAIQGFIGGGMI 132 Query: 125 PAVFSAVFTLFPARLHPVATTIGGVVAVLAPTVGPVVGGWITQTWSWPWLFLVNLVPGAV 184 P+VF+A FT+FP + + + G+VA LAPT +GG+++ +SW WLFLVN+ PG + Sbjct: 133 PSVFAAAFTIFPPSKRSIVSPMIGLVATLAPT----IGGYLSHAFSWHWLFLVNVGPGIL 188 Query: 185 AAVVTPLLLPKEGVQLRAFARLDKWSLVLLAATLASFMIGLKEAPQRGWAAMPCLGLLIG 244 + L+ + L + D W L +AA L S L+E P+ W + ++ Sbjct: 189 VTIAAWNLIDFDEGDLSLLDKFDWWGLFGMAAFLGSLEYVLEEGPRNDWLQDHTIFIMSI 248 Query: 245 SIT-GMALLIRRTLRAAYPIAQLTLFKRRPFAIGCGLSFCLGIGLYGSTYLMPVFLGFVR 303 +T G + R A PI F+ FA G SF +G+GLYG TYL P++L +R Sbjct: 249 ILTVGAIVFFYRVFTAEQPIVDFRAFRNMNFAFGSLFSFVMGVGLYGLTYLYPLYLSMIR 308 Query: 304 RHDAFEIGTVMLVTGVAQLVAAPLAAILESRIGARRLTGAGFALFALGLGWSAIQPRTAD 363 +DA IG + V+G+A AP+A L +R+ R + GF FA+G D Sbjct: 309 GYDALMIGEALFVSGLAMFFTAPVAGFLSNRMDPRLMMMIGFVGFAIGTWLVTGLTADWD 368 Query: 364 FAEMFWPQVVRGVAIMFCLLPPTRIALGALPEAEIADASGLFNLMRNLGGAIGIALIDTI 423 F E+ PQ++RG ++M C++P +ALG LP + + +ASGLFNL RNLGGA+G+A+I+TI Sbjct: 369 FNELLMPQILRGCSLMLCMVPINNLALGTLPPSLMKNASGLFNLTRNLGGAVGLAVINTI 428 Query: 424 LYARSPIYGEDFRVRLLAGDVTAAQAI 450 L R ++ + G+ A I Sbjct: 429 LTRRGDMHYARLAEHVRNGNAEAENMI 455