BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0192.0004.p (305 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0174 [H] COG1893 Ketopantoate reductase Rso Ralstonia solanac... 249 5e-66 BH1763 [H] COG1893 Ketopantoate reductase Bha Bacillus halodurans 219 4e-57 BS_ykpB [H] COG1893 Ketopantoate reductase Bsu Bacillus subtilis 176 4e-44 RSc3361 [H] COG1893 Ketopantoate reductase Rso Ralstonia solanac... 95 2e-19 all1319 [H] COG1893 Ketopantoate reductase Nos Nostoc sp. PCC 7120 87 3e-17 >RSc0174 [H] COG1893 Ketopantoate reductase Rso Ralstonia solanacearum Length = 313 Score = 249 bits (637), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 153/310 (49%), Positives = 205/310 (66%), Gaps = 7/310 (2%) Query: 1 MRVLVVGAGAIGGYFGGRMLQAGRDVTFLVRPRRASELASAGLVIKSPNGDVTLNNPPTV 60 MR+LV+GAG GGYFGGR+ QAG DVTFLVRP RA+ L GL I+SP GD Sbjct: 1 MRILVLGAGGTGGYFGGRLTQAGADVTFLVRPARAARLREHGLEIRSPLGDARFPVQVIT 60 Query: 61 QADKLS-DKFDVVLLSCKAFDLEDAIKSFAPAVGDKTAIIPLLNGMLHLDALDKTFGAQH 119 + + D+VLLSCKA+DL+DAI + PAVG++TA++P+LNG+ HLD LD FGA Sbjct: 61 AGETAAWGHADLVLLSCKAYDLDDAIAAIRPAVGERTAVLPVLNGLSHLDRLDAAFGAAR 120 Query: 120 VLGGLCAIAATLNEKREVVQLQPMQSLGFGER-AGGLSDRVRAIAETFSAINGANA-SEH 177 VLGGLC I+A V+ L P+ S+ FGER + R +AI + F+A + +++ Sbjct: 121 VLGGLCHISAASAPDGAVLHLTPLHSITFGERDSAAPRARTQAIRDVFAAARFDSVLADN 180 Query: 178 VMQDMWEKWVFLASLAASTSLMRTSVGNILAAPGGKDFLLGILDECSAIAADAGHAPGGP 237 VMQDMWEK+VF+ SLA+ T LMR SVG I+A G+ + C+A++A AG+ Sbjct: 181 VMQDMWEKFVFITSLASMTCLMRASVGEIVATDEGRALNEAMYGMCAAVSAAAGYPIRAQ 240 Query: 238 FFQRTRGL--LTTEGSPMTASMFRDIKAGLPVEADHVIGDLVVRADAAKIPVPKLRTAYT 295 RTRGL LT GSPMTASM RD+++G VEADH++GD++ RA AA + V LR A+ Sbjct: 241 --ARTRGLAFLTQAGSPMTASMLRDLESGGRVEADHIVGDMLRRARAAGVDVWLLRVAHA 298 Query: 296 HLKAYEKQRG 305 HL+AY+++ G Sbjct: 299 HLQAYQQRLG 308 >BH1763 [H] COG1893 Ketopantoate reductase Bha Bacillus halodurans Length = 304 Score = 219 bits (559), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 116/301 (38%), Positives = 172/301 (57%), Gaps = 3/301 (0%) Query: 1 MRVLVVGAGAIGGYFGGRMLQAGRDVTFLVRPRRASELASAGLVIKSPNGDVTLNNPPTV 60 M+ L+VGAGA+GGYFG R+ + G DVTFLVR +R ++ GL I+S +G+ T+ Sbjct: 1 MKFLIVGAGAVGGYFGARLAEKGEDVTFLVREKRKEQMKKRGLRIQSIHGNTTIQAKTIT 60 Query: 61 QADKLSDKFDVVLLSCKAFDLEDAIKSFAPAVGDKTAIIPLLNGMLHLDALDKTFGAQHV 120 D + FDVVLL KA+ LE+ I++ P + D+T IIP+LNG+ HLD L K F + V Sbjct: 61 MED--TGLFDVVLLGTKAYHLENVIETIRPFIHDQTVIIPMLNGIAHLDRLRKAFSTEQV 118 Query: 121 LGGLCAIAATLNEKREVVQLQPMQSLGFGERAGGLSDRVRAIAETFSAINGA-NASEHVM 179 +GGLC I +TLNE ++VQ + FGE G S+RV+ I F+ N S+ V+ Sbjct: 119 IGGLCFIESTLNEFGDIVQTSQIHRFVFGELNGERSERVKKIEAAFAGTNAMIEVSDSVL 178 Query: 180 QDMWEKWVFLASLAASTSLMRTSVGNILAAPGGKDFLLGILDECSAIAADAGHAPGGPFF 239 +MW K++F+ +++ T+L VG I P G+ + G+ E AI G Sbjct: 179 TEMWHKYMFITTMSGVTTLYNQPVGPIRELPSGEQVIRGLFAEIGAIMRAVGAPIADQVE 238 Query: 240 QRTRGLLTTEGSPMTASMFRDIKAGLPVEADHVIGDLVVRADAAKIPVPKLRTAYTHLKA 299 ++ + M +SM RD++ GLP+E +H+ G L+ A+ +I P L T YT+L Sbjct: 239 EKQWKQMGGVEYEMKSSMQRDMEKGLPIEREHLQGYLLKLAELHQIQAPILATIYTNLLF 298 Query: 300 Y 300 Y Sbjct: 299 Y 299 >BS_ykpB [H] COG1893 Ketopantoate reductase Bsu Bacillus subtilis Length = 303 Score = 176 bits (447), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 98/289 (33%), Positives = 156/289 (53%), Gaps = 5/289 (1%) Query: 18 RMLQAGRDVTFLVRPRRASELASAGLVIKSPNGDVTLNNPPTVQADKLSDKFDVVLLSCK 77 R+ + G DVTFLVR +RA +L GLVI S G+V+ P + A + + +FDVV+++ K Sbjct: 18 RLSEKGNDVTFLVRQKRAEQLKKTGLVIHSEKGNVSFQ-PELISAGE-TGQFDVVIIASK 75 Query: 78 AFDLEDAIKSFAPAVGDKTAIIPLLNGMLHLDALDKTFGAQHVLGGLCAIAATLNEKREV 137 A+ L I+ P + ++ IIP LNG H + L F + VLGGLC I + L+ K E+ Sbjct: 76 AYSLGQVIEDVKPFIHQESVIIPFLNGYRHYEQLFAAFSKEQVLGGLCFIESALDNKGEI 135 Query: 138 VQLQPMQSLGFGERAGGLSDRVRAIAETFSAING-ANASEHVMQDMWEKWVFLASLAAST 196 FGE G ++R+RA+ E FS + S H+ +D+W+K++F+A+ A T Sbjct: 136 HHTSASHRFVFGEWNGERTERIRALEEAFSGVKAEVIISGHIEKDIWKKYLFIAAQAGIT 195 Query: 197 SLMRTSVGNILAAPGGKDFLLGILDECSAIAADAGHAPGGPFF-QRTRGLLTTEGSPMTA 255 +L + +G ILA G+ ++ E + G P P + + +T+ M + Sbjct: 196 TLFQRPLGPILATEAGRHTAQTLIGEICTVLRKEG-VPADPALEEESFRTMTSMSYHMKS 254 Query: 256 SMFRDIKAGLPVEADHVIGDLVVRADAAKIPVPKLRTAYTHLKAYEKQR 304 SM RD++ G E DH+ G L+ +A + P L T Y +L+ YE ++ Sbjct: 255 SMLRDMENGQTTEGDHLHGFLIEKAKRLSLAAPVLETVYANLQMYEAEK 303 >RSc3361 [H] COG1893 Ketopantoate reductase Rso Ralstonia solanacearum Length = 325 Score = 94.7 bits (234), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 92/328 (28%), Positives = 144/328 (43%), Gaps = 31/328 (9%) Query: 2 RVLVVGAGAIGGYFGGRMLQAGRDVTFLVRPRRASELASAGLVIKSPNGDVTLNNPPTVQ 61 R+ +VGAGA+GGY G R+ QAG V L R L + GL + TL T Sbjct: 3 RICIVGAGAVGGYLGARLAQAGEAVNVLARGATLQALQTVGLCLTEDGVTHTLPVHVTDT 62 Query: 62 ADKLSDKFDVVLLSCKAFDLEDAIKSFAPAVGDKTAIIPLLNGM-------------LHL 108 A L + D+V+++ KA LE+ AP +G T ++ +NG+ L L Sbjct: 63 AAALGVQ-DLVIVAVKAPALENVAAGIAPLIGPDTCVVVAMNGVPWWFFERAGPLQGLRL 121 Query: 109 DALD------KTFGAQHVLGGLCAIAATLNEKRE-VVQLQPMQSLGFGERAGGLSDRVRA 161 A+D + +HVLG C + T + V+ + L GE AGG S R+ A Sbjct: 122 QAVDPHGCIARAIPTRHVLG--CVVHLTCSTASPGHVRHGSGRRLILGEPAGGPSPRLAA 179 Query: 162 IAETFS-AINGANASEHVMQDMWEKWVFLASLAASTSLMRTSVGNILAAPGGKDFLLGIL 220 +A F A S+ + +D+W K ++ + L + IL P F L ++ Sbjct: 180 VAARFERAGLQVECSDAIQRDIWFKLWGNMTMNPVSVLTGATCDRILDDPQVSAFCLAVM 239 Query: 221 DECSAIAADAGHAPGGPFFQ--RTRGLLTTEGSPMTASMFRDIKAGL-PVEADHVIGDLV 277 DE AI A G P Q R +T + SM +D +AG P+E D ++ + Sbjct: 240 DEAKAIGARI----GCPIAQSGEARCAVTRQLGVFKTSMLQDAEAGRGPLEIDALVASVR 295 Query: 278 VRADAAKIPVPKLRTAYTHLKAYEKQRG 305 + +P P++ ++ + + RG Sbjct: 296 EISQHVGVPTPRIDALLGLVRLHAQTRG 323 >all1319 [H] COG1893 Ketopantoate reductase Nos Nostoc sp. PCC 7120 Length = 319 Score = 87.4 bits (215), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 78/308 (25%), Positives = 140/308 (45%), Gaps = 25/308 (8%) Query: 5 VVGAGAIGGYFGGRMLQAGRDVTFLVRPRRASELASAGLVIKSPNGDVTLNNPPTVQADK 64 ++G GA+GGY+G ++ +AG DV FL++ ++ GL+++S +GD TL P V A Sbjct: 8 ILGTGALGGYYGAKLQKAGSDVHFLLK-SDYEKVNQDGLLVESKDGDFTL---PQVNA-- 61 Query: 65 LSD-----KFDVVLLSCKAFDLEDAIKSFAPAVGDKTAIIPLLNGMLHLDALDKTFGAQH 119 +D K DVV+++ K K P V + ++ L NG+ + + + H Sbjct: 62 YNDVAKMPKCDVVVVALKTTQNHLLPKLLPPIVKNDGIVLVLQNGLGVEEEIAEILPQVH 121 Query: 120 VLGGLCAIAATLNEKREVVQLQPMQSLGFGERAGGLS-----DRVRAIAETFSAINGANA 174 ++GGLC + + + L Q + GE A G S DR++ I+ F A Sbjct: 122 IIGGLCFLCSNKVGAGYIHHLDYGQ-ITLGEYAHGYSNMGITDRMQQISHDFQT---AGI 177 Query: 175 SEHVMQDM----WEKWVFLASLAASTSLMRTSVGNILAAPGGKDFLLGILDECSAIAADA 230 S +++D+ W+K V+ + ++ ++A + + ++ E A A Sbjct: 178 SIELLEDLLLGRWKKLVWNIPYNGLSVVLNARTDELMADTYTRTLVEQLMYEVKAGAKSM 237 Query: 231 GHAPGGPFFQRTRGLLTTEGSPMTASMFRDIKAGLPVEADHVIGDLVVRADAAKIPVPKL 290 G F Q T T + P SM D P+E + ++G+ + +A + +P++ Sbjct: 238 GRNIPDSFIQ-TMLDYTVKMKPYRTSMKIDYDECRPLEVEAIVGNPLHKAQEVGVNLPQI 296 Query: 291 RTAYTHLK 298 Y LK Sbjct: 297 NCLYHQLK 304