BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0190.0007.p         (273 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Rv1936 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetr...   132   8e-31
MT1986 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetr...   132   8e-31

>Rv1936 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene
           tetrahydromethanopterin reductase and related
           flavin-dependent oxidoreductases Mtu Mycobacterium
           tuberculosis H37Rv
          Length = 369

 Score =  132 bits (332), Expect = 8e-31,   Method: Compositional matrix adjust.
 Identities = 83/269 (30%), Positives = 138/269 (51%), Gaps = 6/269 (2%)

Query: 2   LDHMLDGRFILGISPGGLLSDAEVFG--NLDADRNAMFLEAINQVLDMWAGKPPYDLQGK 59
            DH+  GRF+LG+   G+  D  ++     + +   M  EA+  +L +W    P++ +GK
Sbjct: 93  FDHLAQGRFMLGVGASGIPGDWALYDVDGKNGEHREMTREALEIMLRIWTEDEPWEHRGK 152

Query: 60  YWNISVKRTLIEDIGQGIVARPLQAPHPPIVVTAVAPFSKGVTEAAARGWDPISANFLMP 119
           YWN +    + E + +  + +P Q PHPPI VT  +  S+ +  A  RG+ P+S + L  
Sbjct: 153 YWNANGIAPMFEGLMRRHI-KPYQKPHPPIGVTGFSAGSETLKLAGERGYIPMSLD-LNT 210

Query: 120 AWVKSHWPKYVEGCARVNRAAEPANWRVAKSVFVAQDAATAKAYATSPDSPYVYYYHQLF 179
            +V +HW    EG  R  R  +  +WR+ + V VA+    A  YA           + L 
Sbjct: 211 EYVATHWDAVEEGALRSGRTPDRRDWRLVREVLVAETDEQAFRYAVDGTMGRAMREYVLP 270

Query: 180 TKLKRSGRLELFKTRRDQPDAEVTLESICDKLIIYGTPESVADQLLAFQEEIGTFGTLLY 239
           T  +  G  + +K     PD EVT E + +   + G+ ++V D+L A  +++G FG LL 
Sbjct: 271 T-FRMFGMTKFYKHNPSVPDDEVTPEYLAENTFVVGSVQTVVDKLEATYDQVGGFGHLLI 329

Query: 240 AGKDWKDRE-LGRQSMILMADKVLPRINA 267
            G D+ D     ++S+ L+A +V+PR+NA
Sbjct: 330 LGFDYSDNPGPWKESLRLLAHEVMPRLNA 358


>MT1986 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene
           tetrahydromethanopterin reductase and related
           flavin-dependent oxidoreductases MtC Mycobacterium
           tuberculosis CDC1551
          Length = 369

 Score =  132 bits (332), Expect = 8e-31,   Method: Compositional matrix adjust.
 Identities = 83/269 (30%), Positives = 138/269 (51%), Gaps = 6/269 (2%)

Query: 2   LDHMLDGRFILGISPGGLLSDAEVFG--NLDADRNAMFLEAINQVLDMWAGKPPYDLQGK 59
            DH+  GRF+LG+   G+  D  ++     + +   M  EA+  +L +W    P++ +GK
Sbjct: 93  FDHLAQGRFMLGVGASGIPGDWALYDVDGKNGEHREMTREALEIMLRIWTEDEPWEHRGK 152

Query: 60  YWNISVKRTLIEDIGQGIVARPLQAPHPPIVVTAVAPFSKGVTEAAARGWDPISANFLMP 119
           YWN +    + E + +  + +P Q PHPPI VT  +  S+ +  A  RG+ P+S + L  
Sbjct: 153 YWNANGIAPMFEGLMRRHI-KPYQKPHPPIGVTGFSAGSETLKLAGERGYIPMSLD-LNT 210

Query: 120 AWVKSHWPKYVEGCARVNRAAEPANWRVAKSVFVAQDAATAKAYATSPDSPYVYYYHQLF 179
            +V +HW    EG  R  R  +  +WR+ + V VA+    A  YA           + L 
Sbjct: 211 EYVATHWDAVEEGALRSGRTPDRRDWRLVREVLVAETDEQAFRYAVDGTMGRAMREYVLP 270

Query: 180 TKLKRSGRLELFKTRRDQPDAEVTLESICDKLIIYGTPESVADQLLAFQEEIGTFGTLLY 239
           T  +  G  + +K     PD EVT E + +   + G+ ++V D+L A  +++G FG LL 
Sbjct: 271 T-FRMFGMTKFYKHNPSVPDDEVTPEYLAENTFVVGSVQTVVDKLEATYDQVGGFGHLLI 329

Query: 240 AGKDWKDRE-LGRQSMILMADKVLPRINA 267
            G D+ D     ++S+ L+A +V+PR+NA
Sbjct: 330 LGFDYSDNPGPWKESLRLLAHEVMPRLNA 358