BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0184.0106.p (413 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SA1341 [GEPR] COG0477 Permeases of the major facilitator superfa... 97 5e-20 TM0342 [GEPR] COG0477 Permeases of the major facilitator superfa... 94 6e-19 BH3886 [GEPR] COG0477 Permeases of the major facilitator superfa... 86 2e-16 TM1336 [GEPR] COG0477 Permeases of the major facilitator superfa... 79 2e-14 SMc03277 [GEPR] COG0477 Permeases of the major facilitator super... 74 6e-13 >SA1341 [GEPR] COG0477 Permeases of the major facilitator superfamily Sau Staphylococcus aureus N315 Length = 405 Score = 97.4 bits (241), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 81/358 (22%), Positives = 183/358 (51%), Gaps = 19/358 (5%) Query: 47 QTGVLQTALTLPFILFAIPAGLLADRVSRRWVMAGSEALRAAALAAILLLLWLGLMTLPL 106 Q G++ +P+ + +PAG L DR++++ +M ++ +R + +I +L + ++++ Sbjct: 46 QVGIVSALSFIPYAILGLPAGALIDRLNKKTIMKCADIIRFVSYLSIPVLSFFNMLSIFQ 105 Query: 107 LALLGFIAVCGTVAYSVAAPALVPSLVTSRQLPAANARIELARTVAFASGPALGGVLVGW 166 + ++ I+ G V +S++ +++PS+V L +AN+ I + V+ GP +GG+L + Sbjct: 106 IYVVAIISGIGLVFHSISEVSIIPSIVKEEDLASANSYIYATQNVSEFLGPIIGGLLYTY 165 Query: 167 VGAA-----PAFGFAAALSAIAVVLLAGIYEPARQPAPRRHPLQDIKEGAAFVMHHALLR 221 +G + + F + ++ ++ + ++ ++ L D+K G +++ ++ +R Sbjct: 166 MGYSILIFIDSMTFLLSFFSLILIKIETKSIFNQEKLSGKNFLSDVKVGFDYLLSNSTIR 225 Query: 222 PVFITQFIFN---TASFLLLAVFVPYAVRHLGLSATGVGTTLAMYGVGMVVGALFATRVM 278 + + + N + ++ + +FV + S+ +G L + +G ++G+L A+ ++ Sbjct: 226 VMAVVVSLSNLIISPYYIYIVMFVK---EDMNQSSQALGLVLGISSLGALIGSLSASFLL 282 Query: 279 KRLAFGTVIGLGPVTGFVAAAVMALTTW--IATPLLAGLSFFLLGVGPILWVISTTTLRQ 336 K FG +I + + ++ +T+ I PLL GL++ + + I+ TLRQ Sbjct: 283 KLFNFGKLIVIILFLDTIFRLMLPFSTYIFILIPLL-GLTY----MTQSILNIAIITLRQ 337 Query: 337 SVTPPSLLGRVSAI-NIMSYGARPLGSALGAIVGGLYGAEACLYLAAAIFAAQALVIL 393 ++LGRV+++ M + RP+G LG I+ G L ++A +F L IL Sbjct: 338 KKCSENMLGRVNSVFKTMVFAFRPIGLFLGGILLENKGGFYALTISAVLFIPLVLYIL 395 >TM0342 [GEPR] COG0477 Permeases of the major facilitator superfamily Tma Thermotoga maritima Length = 413 Score = 94.0 bits (232), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 90/329 (27%), Positives = 154/329 (46%), Gaps = 16/329 (4%) Query: 50 VLQTALTLPFILFAIPAGLLADRVSRRWVMAGSEALRAAALAAILLLLWLGLMTLPLLAL 109 ++ A +P ILF AG++ DR R+++M + LR + + LL + +TLP+L + Sbjct: 48 LMTVAYMVPRILFTPIAGIVGDRGDRKFLMVSMDFLRGFLICFLALLAFRNSITLPVLYV 107 Query: 110 LGFIAVCGTVAYSVAAPALVPSLVTSRQLPAANARIELARTVAFASGPALGGVLVGWVGA 169 + + A+ P +V L AN+ + + R GPALGGV+ G+ G Sbjct: 108 SQIAMAIMDNLFDIPTGAMFPDIVPQDFLMRANSIMGMVRIFPQILGPALGGVIYGFYGI 167 Query: 170 APAF---GFAAALSAIAVVLLAGIYEPARQPAPRRHPLQDIKEGAAFVMHHALLRPVFIT 226 A F G + LSAI+ + + + ++PA L+D+KEG F+ +H L+R + I Sbjct: 168 AIVFLVNGVSFVLSAISEIFIVYSRKVEKKPAKFSQILEDLKEGFLFIWNHELIRTILIF 227 Query: 227 QFIFNTASFLLLAVFVPYAVRH-LGLSATGVGTTLAMYGVGMVVGA-LFATRVMKR---- 280 N L V PY +R + SA G + +G ++G L A+ + K+ Sbjct: 228 ALFLNLLISPLFMVVYPYTIREVMKFSAQEFGFLETSFTLGALLGNFLIASYLSKKNMWK 287 Query: 281 -LAFGTVIGLGPVT--GFVAAAVMALTTWIATPLLAGLSFFLLG-VGPILWVISTTTLRQ 336 + + P+ GF+ +L + L ++F ++G + PI+ V T Q Sbjct: 288 AMKISIFLFELPIVFLGFLVMPDFSLNRLVLFSLFF-ITFLIMGFLNPIINVPLDTAF-Q 345 Query: 337 SVTPPSLLGR-VSAINIMSYGARPLGSAL 364 +TP + R S + +++ G PLGS L Sbjct: 346 KMTPSHIRARAFSFLILVANGVTPLGSVL 374 >BH3886 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 411 Score = 85.9 bits (211), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 94/362 (25%), Positives = 162/362 (44%), Gaps = 22/362 (6%) Query: 54 ALTLPFILFAIPAGLLADRVSRRWVMAGSEALRAAALAAILLLLWLGLMTLPLLALLGFI 113 A +P +L + AG DR + VM SE +RA A +LL ++T P+L + + Sbjct: 51 AFMIPKLLTNLVAGPYLDRFQYKVVMVASEWIRAVAFFVPTVLLVGDMLTAPVLIMAAVL 110 Query: 114 AVCGTVAYSVAAPALVPSLVTSRQLPAANARIELARTVAFASGPALGGVLVGWVGAAPAF 173 + A A V ++ + L N+ +E + GPALGG L+ VG P Sbjct: 111 TGIAEPLFRPAGMAYVAHILPEKHLQRGNSILEGTMQIVMLIGPALGGGLIVLVGPLPLL 170 Query: 174 GF---AAALSAIAVVLLAGIYEPARQPAPRRHPLQDIKEGAAFVMHHALLRPVFITQFIF 230 F A +S +++L ++ + R L KEG +F + +L V + + Sbjct: 171 VFIVIALTVSGFLLLMLDRVHRA--KTNDRASWLTMFKEGMSFYKVYPVLFSVGLLMMMI 228 Query: 231 NTASFLLLAVFVPYAVRHLGLSATGVGTTLAMYGVGMVVGALFA-----TRVMKRLAFGT 285 N +S L +F+PY + HL + G +++Y +GMV+G+ + ++R+ G Sbjct: 229 NFSSGAALPMFLPYVLEHLHGTEFQYGLFMSVYSLGMVLGSFLCGLYPPPKNLRRVMLGY 288 Query: 286 VIGLGPVTGFVAAAVMALTT-WIATPLLAGLSFFLLGVGPILWVISTTTLRQSVTPPSLL 344 + V+ F+ A+ +T+ WIA + FF + + I+ TT Q P L Sbjct: 289 L----TVSSFLMMALGFITSIWIAIGIATMQGFFAMA-----FTINNTTFYQRRVPEHLR 339 Query: 345 GRVSAIN-IMSYGARPLGSALGAIVGGLYGAEAC-LYLAAAIFAAQALVILMSPAVSLTR 402 GRV + +++ A PLG+ +G ++ Y + L L + + L M+ L Sbjct: 340 GRVFTVRALLAQSAIPLGAGVGGLLAEAYRFQVLFLILGGLMLVSTLLAWRMNVFYQLNH 399 Query: 403 QP 404 QP Sbjct: 400 QP 401 >TM1336 [GEPR] COG0477 Permeases of the major facilitator superfamily Tma Thermotoga maritima Length = 390 Score = 78.6 bits (192), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 91/350 (26%), Positives = 162/350 (46%), Gaps = 30/350 (8%) Query: 49 GVLQTALTLPFILFAIPAGLLADRVSRRWVMAGSEALRAAALAAILLLLWLGLMTLPLLA 108 G+ + LP I+ + AG + DR SRR +M + LR + L+ + +T+ LL Sbjct: 41 GLFMISSFLPAIIVSPFAGTVVDRHSRRNMMVVMDILRGVLFMYLFLMEYFSELTMALLL 100 Query: 109 LLGFIAVCGTVAYSVAAPALVPSLVTSRQLPAANARIELARTVAFASGPALGGVLVGWVG 168 ++ + ++ A +L+P LV L AN+ L + ++ GPALG +L+ VG Sbjct: 101 IVTVLVSVFDSFFNPAVDSLLPDLVRKENLVRANSLYRLLKNLSKILGPALGSLLLKVVG 160 Query: 169 AAPAFGFAAALSAIAVVLLAGIYE--------PARQPAPRRHPLQDIKEGAAFVMHHALL 220 A +LS L++GI+E ++ + R+ QDIK ++ + Sbjct: 161 LAGVI-LINSLS----FLISGIFEMFIKVEEKHLKKVSKERNMWQDIKSALLYIRS---V 212 Query: 221 RPVFITQFIFNTASFLL--LAVFVPYAVRHLGLSATGVGTTLAMYGV-GMVVGALFATRV 277 R + +T + +F + V +P V LG S GT ++M G++V L AT + Sbjct: 213 RFILVTILVIAIMNFFTGSMHVLLPEHVSKLGKSEWVYGTLMSMLSFGGLIVTFLMAT-I 271 Query: 278 MKRLAFGTVIGLGPVTGFVAAAVMALT--TWIATPLLAGLSFFLLGVGPILWVISTTTLR 335 R + T +GL V +A V A+T W+ + +FL+G+ L+ I+ TL Sbjct: 272 RTRASVKT-LGLNLVGYGLAVFVFAMTGNHWLMFAM-----YFLIGIFQTLFNINVITLL 325 Query: 336 QSVTPPSLLGRV-SAINIMSYGARPLGSALGAIVGGLYGAEACLYLAAAI 384 Q P + G++ S I+ +S+ P+ + Y A A +++ ++ Sbjct: 326 QLAIPEEMRGKIFSLISAVSFSLLPVSYGFFGFLSS-YVATAHIFITTSM 374 >SMc03277 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 547 Score = 73.9 bits (180), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 72/237 (30%), Positives = 109/237 (45%), Gaps = 8/237 (3%) Query: 50 VLQTALTLPFILFAIPAGLLADRVSRRWVMAGSEALRAAALAAILLLLWLGLMTLPLLAL 109 ++Q A TLP +I AG +AD SRRWVM L A A +++ + +G ++ L+ Sbjct: 59 LVQAASTLPVFFLSILAGAIADNFSRRWVMFAGHCLLALASTTLVISVGIGFISPWLILG 118 Query: 110 LGFIAVCGTVAYSVAAPALVPSLVTSRQLPAANARIELARTVAFASGPALGGVLVGWVGA 169 LGF+A CG A A + ++ R +PAA + + + GPALGGV++ + G Sbjct: 119 LGFLAGCGFALNDPAWHASIGDILHKRDIPAAVTLTSVGYNIVRSGGPALGGVILAFFGP 178 Query: 170 APAFGFAA--ALSAIAVVLLAGIYEPARQPAPRRHPLQDIKEGAAFVMHHALLRPVFITQ 227 AF AA L+ + + + A P PR I +G F +R Sbjct: 179 LTAFALAALCDLTPLGAIWRTKWHVRA-SPLPREKITTAIYDGLRFTAMSFEIRSAVARA 237 Query: 228 FIFNTASFLLLAVFVPYAVR-HLGLSATGVGTTLAMYGVGMVVGAL---FATRVMKR 280 +F AS +LA+ +P VR L G LA +G G V + F R+M + Sbjct: 238 TLFGLASISILAL-LPIVVRDQLASGPIVYGILLAGFGSGAFVAGMSNSFLRRIMSQ 293