BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0184.0103.p         (297 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AF0266 [GER] COG0697 Permeases of the drug/metabolite transporte...    67   4e-11

>AF0266 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT)
           superfamily Afu Archaeoglobus fulgidus
          Length = 276

 Score = 67.4 bits (163), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 71/284 (25%), Positives = 123/284 (43%), Gaps = 18/284 (6%)

Query: 19  MGEWIGVAIALVSSCLGGTAAAITRYLAGNADPITLAILRWAIGFLCVLPAAVLLGAKWP 78
           M +WI +A+ +    L  TA    +Y      PI +A LR+AI     L A +++  K  
Sbjct: 1   MKKWIVLALTVTFWGLAFTA---IKYSVRFLSPIAIASLRFAIA--NTLFAVIIILGKRI 55

Query: 79  RRADLPAVVALGVAFFGVFFVLYNLAMSYTTAARASLALATLPLSTMVVGAMLGIEPLTM 138
           +  DLP V ALG+    V+ V  NL   Y ++  AS+ ++  P+  +++ A+   E +T 
Sbjct: 56  KWKDLPKVFALGIFGVSVYHVFLNLGEVYISSGVASVVISLAPIFVLILSAIFLRERITY 115

Query: 139 RKSIGVSIAVLGVAAALASMARRTNHGRRGALHGLLQRAVAAVHPPLQRARLPCRRHGRR 198
            K +G+ IA LGV      ++  +     G    ++    AA++    ++ L        
Sbjct: 116 SKVVGIIIAFLGVVV----ISEPSYANIYGIALVMVSTVAAAIYTTFGKSLLSKYNPITL 171

Query: 199 RGGXSFTGSL-------ATLREFGPSQWIAG--FYLGIAGGALAFILWVLALERASPTRV 249
                  GS+        ++R  G    + G   +LGI      ++ W   LE+   +R 
Sbjct: 172 TSNAMVLGSIPLYPFLPDSIRSLGGDLNLIGSIVFLGIFSTFFGYLGWYYFLEKEEASRA 231

Query: 250 ANTMTVNPIAAGLLAKQLVGEPITANLVVGLIAVFAGIWIATSE 293
           +  +   P+ + L    L+ EP+T   V G   V  GI+I   +
Sbjct: 232 SVFLLAIPVVSLLAGNILLAEPLTLRTVAGSGLVLLGIYIVVRK 275