BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0184.0074.p (272 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO2761 [GER] COG0697 Permeases of the drug/metabolite transport... 185 7e-47 PA4287 [GER] COG0697 Permeases of the drug/metabolite transporte... 185 1e-46 AGpA485 [GER] COG0697 Permeases of the drug/metabolite transport... 184 1e-46 RSp1638 [GER] COG0697 Permeases of the drug/metabolite transport... 172 8e-43 SMc00642 [GER] COG0697 Permeases of the drug/metabolite transpor... 97 6e-20 >YPO2761 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ype Yersinia pestis Length = 305 Score = 185 bits (470), Expect = 7e-47, Method: Compositional matrix adjust. Identities = 121/291 (41%), Positives = 172/291 (59%), Gaps = 28/291 (9%) Query: 8 LLYPFVAIVLWAGNVIVSRLSTHTIGPQAITFYRLLVAVLLMSPFVARGAWRNRRAIWPH 67 +L+P A+++W+ N +VS++S I P AI+FYR L+A+L +SPF+ G RN +AI + Sbjct: 3 VLFPLFAVIIWSVNAVVSKISATAIDPAAISFYRWLLALLTLSPFLLLGVVRNWQAIRVY 62 Query: 68 LGPLAILGFLAMCLFQSLSYLAAETTTATNMAVFTALTPLLTVALSAALLGEPPTLGMIC 127 L +LG L M L+QSL+Y AA + +A M + ++L PLLTV +S LL PT+G+ Sbjct: 63 WWKLMLLGMLGMVLYQSLAYYAAHSVSALFMGILSSLIPLLTVLISIVLLRVAPTVGIAL 122 Query: 128 GAPLSFAGLVYLVSGGDLSSLLQNGVHAGDALMLLAAIVYALYGVLLKRWNLLITGWQST 187 G+ LS GLV+L+S G+ LLQ+G+ G+ +ML A+ YALYGVL KRW + + WQS Sbjct: 123 GSLLSLGGLVWLISAGNPVQLLQHGIGKGELMMLGASASYALYGVLTKRWAIQLPNWQSL 182 Query: 188 YMQALCALAVMFPAFLATP----------------------AP------LRXLGPNRCAI 219 YMQ + + ++ P FL TP AP + LG N +I Sbjct: 183 YMQIVFGVVLLLPGFLMTPDVQLTAQNIPLVLFAGIPASILAPYLWIQGVMRLGANTASI 242 Query: 220 FMNLLPVLTAAAAIVVLGEPVRPFHVIGGGLALLGVACAQALPRPVKTARD 270 FMNL PV TA A+V L E + +H+IGGG+ L GV AQ L P++ D Sbjct: 243 FMNLTPVFTAIIAVVFLHEQLHSYHLIGGGITLAGVVLAQRLRSPLRRNLD 293 >PA4287 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 296 Score = 185 bits (469), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 110/291 (37%), Positives = 170/291 (58%), Gaps = 28/291 (9%) Query: 9 LYPFVAIVLWAGNVIVSRLSTHTIGPQAITFYRLLVAVLLMSPFVARGAWRNRRAIWPHL 68 L+P +A+ +WAGN +V++L+ I P I F+R L+ L ++PF+ RNRR I +L Sbjct: 4 LFPLLAVFIWAGNTVVNKLAVGIIQPAEIGFFRWLLVGLALTPFMLGPVLRNRRYILANL 63 Query: 69 GPLAILGFLAMCLFQSLSYLAAETTTATNMAVFTALTPLLTVALSAALLGEPPTLGMICG 128 G +LG L M ++QSL+Y AA T+ATNM + +L PL+++ L++++L G + G Sbjct: 64 GKFVVLGLLGMAVYQSLAYYAAALTSATNMGIILSLMPLMSLGLASSILAHRLNAGALLG 123 Query: 129 APLSFAGLVYLVSGGDLSSLLQNGVHAGDALMLLAAIVYALYGVLLKRWNLLITGWQSTY 188 A +S AG+V ++S G L +LL++GV+ GDA+M++A + YA+Y VLLK+W+L + Q Y Sbjct: 124 ALVSLAGVVLVISQGHLGALLEHGVNLGDAMMIVATLAYAVYSVLLKKWSLKLPAMQLLY 183 Query: 189 MQALCAL-------------------------AVMFPAFLATPAPLR---XLGPNRCAIF 220 +Q L A+ A +F + +A A + LGP+R A+F Sbjct: 184 LQVLVAILALLPLYLLSPRTGLNAANLPLVLYAALFASIVAALAWMHGVARLGPSRMALF 243 Query: 221 MNLLPVLTAAAAIVVLGEPVRPFHVIGGGLALLGVACAQALPRPVKTARDA 271 NLLP++TA A +VLGE + H++GG L L GV A+ R R A Sbjct: 244 FNLLPIITACIATLVLGERLTVHHLVGGALTLAGVLLAEFWQRRPARLRSA 294 >AGpA485 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 309 Score = 184 bits (468), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 113/292 (38%), Positives = 164/292 (56%), Gaps = 28/292 (9%) Query: 8 LLYPFVAIVLWAGNVIVSRLSTHTIGPQAITFYRLLVAVLLMSPFVARGAWRNRRAIWPH 67 LL+ +A+++W GN IVS+L+ I P I F R +A ++++P V R AWR+RR I H Sbjct: 12 LLFSLLAVLIWVGNTIVSKLAAGAIAPGTIAFERWFIAFVILTPLVYRDAWRHRRTIAAH 71 Query: 68 LGPLAILGFLAMCLFQSLSYLAAETTTATNMAVFTALTPLLTVALSAALLGEPPTLGMIC 127 L L +LG L M Q L Y AA TTATNMA+ +L PLLT+ LSA L E P+ + Sbjct: 72 LPKLILLGLLGMAACQGLGYYAAGLTTATNMAIMLSLVPLLTLILSAVFLAERPSSLAVI 131 Query: 128 GAPLSFAGLVYLVSGGDLSSLLQNGVHAGDALMLLAAIVYALYGVLLKRWNLLITGWQST 187 G +S +G+ ++ GD S LL GV GDA+ML A + YA YG+LL+RW + + W S Sbjct: 132 GGIISLSGIFIVLGQGDPSRLLSQGVGRGDAMMLAAVLAYAGYGILLRRWAIPLATWTSI 191 Query: 188 YMQALCALAVMFPAF-LATPAPL---------------------------RXLGPNRCAI 219 Y+Q A+ ++ P++ L+ P+ L + LG R AI Sbjct: 192 YVQIGAAVVLLVPSYLLSAPSALTLPNTAMVLYAAIPGSILAPFVWMTAVKHLGAARTAI 251 Query: 220 FMNLLPVLTAAAAIVVLGEPVRPFHVIGGGLALLGVACAQALPRPVKTARDA 271 FMNL+P+ TA A + LGE + +H++GGG+ + G+ Q P K+ + A Sbjct: 252 FMNLIPIFTAIVAAIFLGEALYIYHLLGGGMTVAGIILVQRKPFREKSGQKA 303 >RSp1638 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 297 Score = 172 bits (436), Expect = 8e-43, Method: Compositional matrix adjust. Identities = 104/282 (36%), Positives = 156/282 (55%), Gaps = 28/282 (9%) Query: 8 LLYPFVAIVLWAGNVIVSRLSTHTIGPQAITFYRLLVAVLLMSPFVARGAWRNRRAIWPH 67 + YP +A+++WA N IVS+ + + P AI+ YR ++A +++PF AR WR RR + P Sbjct: 3 VFYPLLAVLVWAANTIVSKAAAGVLDPAAISLYRWVIAAAVLTPFWARPLWRQRRDVLPW 62 Query: 68 LGPLAILGFLAMCLFQSLSYLAAETTTATNMAVFTALTPLLTVALSAALLGEPPTLGMIC 127 L L++L L + ++Q LSY AA +T+ATN+ V AL P+L + ++ + +P + Sbjct: 63 LPRLSVLALLGLVMYQCLSYYAAYSTSATNIGVICALIPMLGLIINGVVFRQPVGAPAVA 122 Query: 128 GAPLSFAGLVYLVSGGDLSSLLQNGVHAGDALMLLAAIVYALYGVLLKRWNLLITGWQST 187 G +S G++YL+ G +SL GV+ GD L+L+ + YALY +L +RW W + Sbjct: 123 GIAVSLLGVLYLLGRGHPASLFDGGVNRGDVLVLIGSAAYALYNILYRRWAPPFGQWLNL 182 Query: 188 YMQALCALAVMFP-AF----LATPAP-----------------------LRXLGPNRCAI 219 Y+QAL A+ ++ P AF LA P L LG R + Sbjct: 183 YLQALLAVVMLLPLAFTARSLAIPQQGIGMVLFAGIGASIVAMYWWMLGLARLGSERTVV 242 Query: 220 FMNLLPVLTAAAAIVVLGEPVRPFHVIGGGLALLGVACAQAL 261 MNLLPV TA A +LGE + +H IGGGL LLGV+ Q + Sbjct: 243 MMNLLPVFTALMASAMLGETIHGYHWIGGGLILLGVSLVQGI 284 >SMc00642 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 296 Score = 96.7 bits (239), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 83/302 (27%), Positives = 135/302 (44%), Gaps = 55/302 (18%) Query: 7 ALLYPFVAIVLWAGNVIVSRLSTHTIGPQAITFYR----LLVAVLLMSPFVARGAWRNRR 62 A Y + + W GN + +++ + P +T R L V ++LM+P + R W+ R Sbjct: 5 AYFYLGITALFWGGNSVAGKMAVGHVSPMMLTTLRWLLALAVILVLMTPQIRRD-WQKIR 63 Query: 63 AIWPHLGPLAILGFLAMCLFQSLSYLAAETTTATNMAVFTALTPLLTVALSAALLGEPPT 122 W L +GF +F + Y A + T+A N + A P+L + AL + Sbjct: 64 QHWLQLLAYGAVGF---TMFNAFLYSAVQYTSAINAVILQAGIPMLIFIFNFALFKMKAS 120 Query: 123 LGMICGAPLSFAGLVYLVSGGDLSSLLQNGVHAGDALMLLAAIVYALYGVLLK-----RW 177 L + G ++ G++ + GDL+SL++ + GDALM+LA IVYA Y V L+ W Sbjct: 121 LAQVIGFTVTLVGVLITAAHGDLASLMRLSFNFGDALMILACIVYAAYTVALRWKPAMHW 180 Query: 178 NLLI-----------------------------TGWQSTYMQALCALAVMFPAFLATPAP 208 I TGW A+ A +FP+ ++ Sbjct: 181 QSFIAAPAFGALLSAIPLLLWEMGKGTAIMPDATGW------AIVIYAAIFPSLMSQVLY 234 Query: 209 LR---XLGPNRCAIFMNLLPVLTAAAAIVVLGEPVRPFHVIGGGLALLGVACAQ----AL 261 +R +G NR +F+N +PV +++++GE PFH+ L L G+A A+ L Sbjct: 235 VRGVEMIGANRAGLFINAIPVFGTLLSVLLVGEIFHPFHLAALALVLGGIAIAERGRPKL 294 Query: 262 PR 263 PR Sbjct: 295 PR 296