BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0182.0104.p (372 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr6852 [T] COG0642 Signal transduction histidine kinase Mlo Mes... 415 e-116 CC1768 [T] COG0642 Signal transduction histidine kinase Ccr Caul... 341 2e-93 PA4494 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 153 5e-37 RSc0039 [T] COG0642 Signal transduction histidine kinase Rso Ral... 140 4e-33 SMc02585 [T] COG0642 Signal transduction histidine kinase Sme Si... 114 4e-25 >mlr6852 [T] COG0642 Signal transduction histidine kinase Mlo Mesorhizobium loti Length = 450 Score = 415 bits (1067), Expect = e-116, Method: Compositional matrix adjust. Identities = 210/359 (58%), Positives = 267/359 (74%), Gaps = 1/359 (0%) Query: 10 LRYRADINNRELLVALALDVAALTALLYLSGGATNPFTSLYLLQVTLGAVLLDAPSTWSL 69 LR + I+N +L VAL D+AALT LYLSGGA+NPF SLYLLQ+TLGA LL STWSL Sbjct: 89 LRGQRPISNAQLFVALIFDMAALTTQLYLSGGASNPFVSLYLLQITLGAALLTPWSTWSL 148 Query: 70 VALVCMNFAWLTSYYRPLELPLHGFADAFNLYIAGTFIGLVLDAVLLVVFMTRINRNLRD 129 VA F +LT ++P+ +P HG +D L+I G FI VL A L+V+FMTRINRNLR+ Sbjct: 149 VAAASACFVFLTFQFQPIAIPHHGGSDLLALHIRGMFICFVLAAGLIVIFMTRINRNLRE 208 Query: 130 RDLRLAALRQHAAEQDHIVRIGLLASGAAHELGTPLASLSVILGDWRRMPALASDPEMSQ 189 RD LA LRQH+AE+DHIVR+GLLASGAAHELGTPL+++SVIL DWR++ ++ + E++ Sbjct: 209 RDAYLADLRQHSAEEDHIVRMGLLASGAAHELGTPLSTISVILSDWRQIRSVTRNRELAG 268 Query: 190 DLGEMEISVQRCKSIVTGILLSAGEARGEGSSPTTVAAFLTALVEEWRTTRPSATLYFRN 249 D+ EM+ ++RCKSIV+GIL+S+G+ARGEG+ T++ FL LV+EWR +R L ++N Sbjct: 269 DVAEMQAQIERCKSIVSGILMSSGQARGEGTIRTSIRHFLGDLVQEWRVSRQPLNLEYKN 328 Query: 250 AFGSDLAIVSDIALKQAIFNVLDNAAEVSRDWIELTAERNADRLVLSVTDRGPGFSREML 309 F D IVSD ALKQ IFNV DNA E S+DW+ + A R ++LV+SV DRGPGF +L Sbjct: 329 DFEPDEQIVSDTALKQVIFNVFDNALEASQDWVGVAAGRQGEKLVISVRDRGPGFDEGIL 388 Query: 310 AHIGKPYQSTKGSPGSGLGLFLVVNVVRKLGGVVAARNRPDIGAAVRLELPLSTLAIGD 368 A +G+PY S+KG PG GLGLFLVVNVVRKLGG +ARN + GA V L LPL+ L GD Sbjct: 389 AALGQPYMSSKGRPGGGLGLFLVVNVVRKLGGDFSARNM-EQGACVTLSLPLAALTDGD 446 >CC1768 [T] COG0642 Signal transduction histidine kinase Ccr Caulobacter vibrioides Length = 448 Score = 341 bits (874), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 184/339 (54%), Positives = 231/339 (68%), Gaps = 5/339 (1%) Query: 33 TALLYLSGGATNPFTSLYLLQVTLGAVLLDAPSTWSLVALVCMNFAWLTSYYRPLELPLH 92 T LY SGGATNPFT+LYLL V LGAVLL+A +TW++VAL+ F L + RP+ P Sbjct: 112 TIQLYFSGGATNPFTTLYLLHVILGAVLLEARATWAIVALISFFFVALIGFNRPIIAP-- 169 Query: 93 GFADA--FNLYIAGTFIGLVLDAVLLVVFMTRINRNLRDRDLRLAALRQHAAEQDHIVRI 150 G +D F LYI G +GL+LDAVLLV F+ RIN NLR D RLA LRQ AE+ HI+R+ Sbjct: 170 GLSDRAFFELYIMGMLVGLLLDAVLLVTFVGRINTNLRSHDARLAELRQREAEEAHIIRM 229 Query: 151 GLLASGAAHELGTPLASLSVILGDWRRMPALASDPEMSQDLGEMEISVQRCKSIVTGILL 210 GLLASGAAHELGTPLA+L VILGDWRR+PA+AS+ E++Q+L +M V+RCK+IVTG+LL Sbjct: 230 GLLASGAAHELGTPLATLDVILGDWRRVPAIASNAELAQELEDMRGEVRRCKAIVTGVLL 289 Query: 211 SAGEARGEGSSPTTVAAFLTALVEEWRTTRPSATLYFRNAFGSDLAIVSDIALKQAIFNV 270 SAGEAR +T+ F+ +V EWR +R A L + I+++ LKQ I N+ Sbjct: 290 SAGEARSGEVRVSTLRGFMDEVVAEWRASRADAPLLYETDLRDATPIIAESTLKQGIHNI 349 Query: 271 LDNAAEVSRDWIELTAERNADRLVLSVTDRGPGFSREMLAHIGKPYQSTKGSPGSGLGLF 330 LDNA E S + L+A + + V D GPGF+ E LA GKPY STKG GSGLGLF Sbjct: 350 LDNALEASGSALRLSAATRDGWIRIVVEDDGPGFTSEALADFGKPYNSTKGRAGSGLGLF 409 Query: 331 LVVNVVRKLGGVVAARNRPDIGAAVRLELPLSTLAIGDH 369 L+VNV+RKLGGV A N GA V + LP++ L + H Sbjct: 410 LLVNVLRKLGGVAEAENLVG-GARVSIRLPVAMLEVARH 447 >PA4494 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 422 Score = 153 bits (387), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 116/359 (32%), Positives = 186/359 (51%), Gaps = 7/359 (1%) Query: 8 TWLRYRAD--INNRELLVALALDVAALTALLYLSGGATNPFTSLYLLQVTLGAVLLDAPS 65 T LR RA + ++E V LA D+ + LLY SGG+TNPF S YL+ +T+ A L Sbjct: 63 TALRLRAPWPVTDQEYAVQLACDLIIHSTLLYYSGGSTNPFVSYYLVPLTIAAATLPWIY 122 Query: 66 TWSLVALVCMNFAWLTSYYRPLELP-LHGFADAFNLYIAGTFIGLVLDAVLLVVFMTRIN 124 + L L + L +Y PL L + A NL++ G ++ L A + F+ +++ Sbjct: 123 SMVLSGLALTGYTLLLIWYHPLHLQAVQHEAMLINLHLFGMWLNFALSAAFITFFVVKMS 182 Query: 125 RNLRDRDLRLAALRQHAAEQDHIVRIGLLASGAAHELGTPLASLSVILGDWRRMPALASD 184 LR + A R+ + ++ + A+GAAHELGTPLA++SV+L + R+ D Sbjct: 183 EALRWQAHMQAERREESMRDQQLLAVATQAAGAAHELGTPLATMSVLLNELRQ--ERPQD 240 Query: 185 PEMSQDLGEMEISVQRCKSIVTGILLSAGEARGEGSSPTTVAAFLTALVEEWRTTRPSAT 244 P + +DL ++ V++CK + ++ +A R + + A +L +++ W RP A+ Sbjct: 241 PTLQEDLALLQEQVKQCKHTLQQLVRAAEADRRQAIEEQSAAEWLESVLRRWHLMRPEAS 300 Query: 245 LYFRN-AFGSDLAIVSDIALKQAIFNVLDNAAEVSRDWIELTAERNADRLVLSVTDRGPG 303 ++ GS + L QA+ N+L+NAA+ D +++ + ++ + LS+ D G G Sbjct: 301 YRYQCLGLGSAPRLTPPTDLSQALLNLLNNAADACPDDLDIRLDWDSSSICLSIRDHGVG 360 Query: 304 FSREMLAHIGKPYQSTKGSPGSGLGLFLVVNVVRKLGGVVAARNRPDIGAAVRLELPLS 362 + IGKP+ +TKG G GLGLFL V + GG V N D G L LP S Sbjct: 361 VPLAIAEQIGKPFFTTKGK-GFGLGLFLSQASVTRAGGTVKLYNHEDGGTLTELRLPRS 418 >RSc0039 [T] COG0642 Signal transduction histidine kinase Rso Ralstonia solanacearum Length = 448 Score = 140 bits (354), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 109/370 (29%), Positives = 182/370 (49%), Gaps = 29/370 (7%) Query: 10 LRYRADINNRELLVALALDVAALTALLYLSGGATNPFTSLYLLQVTLGAVLLDAPSTWSL 69 +R + + E+ V L +D+ AL+ALLY +GGATNPF S YL + + A +L L Sbjct: 69 VRRDRPVRHIEITVQLLVDLTALSALLYFTGGATNPFVSFYLPALAIAAAMLPIAHVVGL 128 Query: 70 VALVCMNFAWLTSYYRPLELPLHGFADAFNLYIAGTFIGLVLDAVLLVVFMTRINRNLRD 129 ++ + Y PL+L ADA ++AG +I V + ++ F R++ LR+ Sbjct: 129 TLYALAAYSVMLGNYIPLDL--LDQADAVPYHLAGMWIDFVASSAMIAGFTARLSAALRE 186 Query: 130 RDLRLAALRQHAAEQDHIVRIGLLASGAAHELGTPLASLSVILGDWR---RMPALASDPE 186 R+ LA R+ + I + + AHE+GTPL++++VI G+ + R P P Sbjct: 187 REAELADARERLLREQRIEALVSQGASVAHEMGTPLSTVAVITGELQHDARQPDSPLAP- 245 Query: 187 MSQDLGEMEISVQRCKSIVTGILLSAGEARGEGSSPTTVAAFLTALVEEWRTTRPSATLY 246 +DL +E ++ C++ + + + + +P + +L A + W+ P L+ Sbjct: 246 YREDLRAIEQQLELCRAALARL-----QRKPNDGTPEPLGLWLPAFTQTWQLRHPDIRLH 300 Query: 247 FRNAFGSDLAIVSDIALKQAIFNVLDNAA----EVSRDWIE--LTA--ERNAD------- 291 ++ + + + + Q + +LDNAA + RD + LTA + NAD Sbjct: 301 TESSPAAQAVELDAVVVGQILTILLDNAARSQQQAGRDQVPLLLTARIDANADTVREAPR 360 Query: 292 RLVLSVTDRGPGFSREMLAHIGK-PYQSTKGSPGSGLGLFLVVNVVRKLGGVVAARNRPD 350 ++VLSV D G G ++ +G+ P S G G G+GL+L R+LGG V R+ P Sbjct: 361 QIVLSVVDTGLGVPDDLRTALGRTPVPSRHG--GHGIGLYLAATTARRLGGTVELRSNPP 418 Query: 351 IGAAVRLELP 360 GA L LP Sbjct: 419 QGAIAELRLP 428 >SMc02585 [T] COG0642 Signal transduction histidine kinase Sme Sinorhizobium meliloti Length = 433 Score = 114 bits (285), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 90/344 (26%), Positives = 160/344 (46%), Gaps = 13/344 (3%) Query: 25 LALDVAALTALLYLSGGATNPFTSLYLLQVTLGAVLLDAPSTWSLVALVCMNFAWLTSYY 84 L +D+A LTALL+++GG NPF L + V + + P + L L + L + Sbjct: 85 LGIDLAQLTALLFITGGLANPFAPLLCVPVIISSASQPKPQSIVLAGLAVLGVTALA--F 142 Query: 85 RPLELPLHGFADAF--NLYIAGTFIGLVLDAVLLVVFMTRINRNLRDRDLRLAALRQHAA 142 P LP + + AG + +V + R++ + L A Sbjct: 143 SPFPLPWYPGTLLLMPRVLTAGIWFAIVSMTAFAAFYTYRVSLEASELSEALTATELVLQ 202 Query: 143 EQDHIVRIGLLASGAAHELGTPLASLSVILGDWRRMPALASDPEMSQDLGEMEISVQRCK 202 + H+ ++ LA+ AAHELGTPLA++SV+ + R L DP +D+ + +RC+ Sbjct: 203 REKHLSQLDGLAAAAAHELGTPLATISVVAKEMER--ELGDDPRFGEDVHLLRSQSERCR 260 Query: 203 SIVTGILLSAGEARGEGSSPTTVAAFLTALVEEWRTTRPSATLYFRNAFGSDLAIVSDIA 262 I+ + + E+ E +++ + ++ R L + S+ + + Sbjct: 261 DILRRLTTLSSESE-EHMRLLPLSSLIEEVMAPHREFGIEIELKEQGDRASEPVGIRNAG 319 Query: 263 LKQAIFNVLDNAAEVSRDWIELTAERNADRLVLSVTDRGPGFSREMLAHIGKPY----QS 318 + + N+L+NA + +R + +T E A+R+ +++ D G GFS ++LA IG+PY Q Sbjct: 320 ILYGLGNLLENAVDYARKKVTVTTEHTAERVRVTIEDDGDGFSPDILARIGEPYVTRRQK 379 Query: 319 TKGSPGSGLGLFLVVNVVRKLGGVVAARN--RPDIGAAVRLELP 360 + G GLGLF+ ++ + G + N GA V +E P Sbjct: 380 DDSAGGLGLGLFIAKTLLERSGARLRFENGGSKHPGARVSVEWP 423