BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0182.0081.p (450 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM0689 [GEPR] COG0477 Permeases of the major facilitator superf... 518 e-146 RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 476 e-134 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 463 e-130 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 439 e-123 PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 279 9e-75 >STM0689 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 518 bits (1334), Expect = e-146, Method: Compositional matrix adjust. Identities = 252/420 (60%), Positives = 323/420 (76%), Gaps = 3/420 (0%) Query: 5 LVQQATVKSR---INAILRATSGNFLEQFDFFLFGFYASAIGKAFFPSDNETASLLNTFG 61 + Q SR AILR TSGNFLEQFDFFLFGFYA+ I + FFP+++E ASL+ TF Sbjct: 1 MAQHTPATSRAGTFGAILRVTSGNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFA 60 Query: 62 VFWLGALMRPVGAIVLGAYIDRIGRRQGLIITLSIMAVGTVIIAFCPSYATIGIAAPIIV 121 VF G LMRPVGAIVLGAYIDRIGRR+GL++TL+IM GT++IA P Y TIG+AAP +V Sbjct: 61 VFGSGFLMRPVGAIVLGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALV 120 Query: 122 LAGRLLQGFSAGVEVGGVSVYLAEIATPGNRGFYTSFQSSSQQVAIFVAAIVGYLLNESM 181 L GRLLQGFSAGVE+GGVSVYL+EIATPGN+GFYTS+QS+SQQVAI VAA++GY LN ++ Sbjct: 121 LLGRLLQGFSAGVELGGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITL 180 Query: 182 PLEAVASWGWRIPFFLGCLIIPLIFFLRRTLEETPEFLAMKKHPTAREVFASALVHWHTV 241 +A++ WGWRIPFF+GC+IIPLIF LRR+L+ET FL K P RE+FA+ +W + Sbjct: 181 GHDAISEWGWRIPFFIGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFATIAKNWRII 240 Query: 242 VLGMMMAILTTTTFYFVTVYAPTFGKTVLKLSTQDALLVTLLVAVTNFIWNPIGGTVSDR 301 G ++ +TTTTFYF+TVY PT+G+TVL LS +D+L+VT+LV V+NFIW PIGG +SDR Sbjct: 241 TAGTLLVAMTTTTFYFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDR 300 Query: 302 IGRKPVLLAIAGLALMTAYPALSWLVSAPSFGKLLAVAMMFSFYFGTYSGTMLGALVEIV 361 IGR+ VL+ I LAL+T +P + WL +AP F ++ V + FSF+FG Y+G M+ AL E++ Sbjct: 301 IGRRAVLMGITLLALITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVM 360 Query: 362 PAHVRTTCFSLAFAFAAALFGTFTPLASTWLIERTNDKASPGFWLMFAAALGIIAVLTIY 421 P +VRT FSLAF+ A A+FG TP ST L++ T DK+SPG+WLM AA G+ A ++ Sbjct: 361 PVYVRTVGFSLAFSLATAIFGGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAATAMLF 420 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 476 bits (1224), Expect = e-134, Method: Compositional matrix adjust. Identities = 225/411 (54%), Positives = 303/411 (73%) Query: 12 KSRINAILRATSGNFLEQFDFFLFGFYASAIGKAFFPSDNETASLLNTFGVFWLGALMRP 71 +S+ +I R SGNFLE +DF ++G+YA AI FFP+DNE SL+ + F +G LMRP Sbjct: 8 ESKARSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFGVGFLMRP 67 Query: 72 VGAIVLGAYIDRIGRRQGLIITLSIMAVGTVIIAFCPSYATIGIAAPIIVLAGRLLQGFS 131 +GA++LGAYIDR GRR GLI+TL +MA GT++IA P YATIG+AAP++VL GRLLQGFS Sbjct: 68 LGALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRLLQGFS 127 Query: 132 AGVEVGGVSVYLAEIATPGNRGFYTSFQSSSQQVAIFVAAIVGYLLNESMPLEAVASWGW 191 AGVE+GGVSVYLAEI+TPG +GF+ S+QS+SQQVA+ AA++G LL+ + + + WGW Sbjct: 128 AGVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEMGEWGW 187 Query: 192 RIPFFLGCLIIPLIFFLRRTLEETPEFLAMKKHPTAREVFASALVHWHTVVLGMMMAILT 251 R+PF +GCLI+P +F +RR+L+ET EF K P E+F S +W V G ++ ++T Sbjct: 188 RVPFLVGCLIVPFLFLIRRSLQETEEFKQRKHRPALGEIFRSMGENWRLVGAGTLLVVMT 247 Query: 252 TTTFYFVTVYAPTFGKTVLKLSTQDALLVTLLVAVTNFIWNPIGGTVSDRIGRKPVLLAI 311 T +FY +T Y PTFGK+VL LS D+L+VTL V +NF W P+ G+VSDRIGR+P+L+ Sbjct: 248 TVSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRRPLLITF 307 Query: 312 AGLALMTAYPALSWLVSAPSFGKLLAVAMMFSFYFGTYSGTMLGALVEIVPAHVRTTCFS 371 L L+TAYPA+ WL++ PSFG+LLAV + SF +G+Y+G M+ L EI+P VRTT FS Sbjct: 308 TALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAVRTTGFS 367 Query: 372 LAFAFAAALFGTFTPLASTWLIERTNDKASPGFWLMFAAALGIIAVLTIYR 422 LA++ A A+FG FTP +TWLI T +KA PG WL FAA G++A L + + Sbjct: 368 LAYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATLIVVK 418 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 463 bits (1192), Expect = e-130, Method: Compositional matrix adjust. Identities = 226/425 (53%), Positives = 301/425 (70%) Query: 12 KSRINAILRATSGNFLEQFDFFLFGFYASAIGKAFFPSDNETASLLNTFGVFWLGALMRP 71 +S+ AI R SGNFLE FDF ++G+YA+AI FFP+ N SL+ + F G LMRP Sbjct: 8 ESKARAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFGAGFLMRP 67 Query: 72 VGAIVLGAYIDRIGRRQGLIITLSIMAVGTVIIAFCPSYATIGIAAPIIVLAGRLLQGFS 131 +GAIVLGAYIDR GRR GLI+TL +MA GT++IA P Y TIG+AAP++VL GRLLQGFS Sbjct: 68 LGAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRLLQGFS 127 Query: 132 AGVEVGGVSVYLAEIATPGNRGFYTSFQSSSQQVAIFVAAIVGYLLNESMPLEAVASWGW 191 AG E GGVSVYL+EIATPG +GFY S+QS SQQVA+ AA++G LL+ + + + WGW Sbjct: 128 AGGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEMGEWGW 187 Query: 192 RIPFFLGCLIIPLIFFLRRTLEETPEFLAMKKHPTAREVFASALVHWHTVVLGMMMAILT 251 R+PF +GCLI+P +FF+RR+L ET EF K PT E+ S +W G ++A++T Sbjct: 188 RVPFLIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGENWRLAGAGTLLAVMT 247 Query: 252 TTTFYFVTVYAPTFGKTVLKLSTQDALLVTLLVAVTNFIWNPIGGTVSDRIGRKPVLLAI 311 T +FY +T Y PTFG+ VL +S D+L+VTL V +N IW P+ G++SDRIGR+ L+ Sbjct: 248 TVSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGRRTPLIVF 307 Query: 312 AGLALMTAYPALSWLVSAPSFGKLLAVAMMFSFYFGTYSGTMLGALVEIVPAHVRTTCFS 371 + L L+TAYPA++WL++ PSFG+LLAV + SF +G Y+G M+ L EI+P +RTT FS Sbjct: 308 SALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQLRTTGFS 367 Query: 372 LAFAFAAALFGTFTPLASTWLIERTNDKASPGFWLMFAAALGIIAVLTIYRGTPKPSRAE 431 LA++ A A+FG FTP +T LI T +KA PG WL FAA G++A LT+ + P+P+ Sbjct: 368 LAYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATLTVVKPQPRPAAMP 427 Query: 432 KPSLR 436 P L Sbjct: 428 DPLLE 432 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 439 bits (1130), Expect = e-123, Method: Compositional matrix adjust. Identities = 227/397 (57%), Positives = 296/397 (74%) Query: 9 ATVKSRINAILRATSGNFLEQFDFFLFGFYASAIGKAFFPSDNETASLLNTFGVFWLGAL 68 A+ KS+ AI R SGNFLE +DF ++GFYA+AI K FFP DN ASL+ + F G L Sbjct: 2 ASNKSKGVAIFRVVSGNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGFL 61 Query: 69 MRPVGAIVLGAYIDRIGRRQGLIITLSIMAVGTVIIAFCPSYATIGIAAPIIVLAGRLLQ 128 MRP+GA+ LGAYIDR GRRQGLIITL +MA+GT++IAF P YAT+G+AAP++VL GRLLQ Sbjct: 62 MRPLGAVFLGAYIDRHGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLLQ 121 Query: 129 GFSAGVEVGGVSVYLAEIATPGNRGFYTSFQSSSQQVAIFVAAIVGYLLNESMPLEAVAS 188 GFSAGVE+GGVSVYL+EIATPG +GF+ S+QS+SQQVA+ A ++G LLN+ + + + Sbjct: 122 GFSAGVELGGVSVYLSEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMGE 181 Query: 189 WGWRIPFFLGCLIIPLIFFLRRTLEETPEFLAMKKHPTAREVFASALVHWHTVVLGMMMA 248 WGWR+PFF+GCLI+P +F +RR+LEETPEF A P+ +V S ++ V+ G M Sbjct: 182 WGWRVPFFIGCLIVPALFVIRRSLEETPEFEARTHRPSLSQVLRSIGQNFGVVLAGTAMV 241 Query: 249 ILTTTTFYFVTVYAPTFGKTVLKLSTQDALLVTLLVAVTNFIWNPIGGTVSDRIGRKPVL 308 ++TT +FY +T Y PTFGK L+LS D+LLVT+ + ++NFIW P+ G SDRIGRKP+L Sbjct: 242 VMTTVSFYLITAYTPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKPLL 301 Query: 309 LAIAGLALMTAYPALSWLVSAPSFGKLLAVAMMFSFYFGTYSGTMLGALVEIVPAHVRTT 368 L + LAL+TAYPALSWLV PSF LL V + SF + +Y+G M+ AL E++PA VRTT Sbjct: 302 LGASALALLTAYPALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVRTT 361 Query: 369 CFSLAFAFAAALFGTFTPLASTWLIERTNDKASPGFW 405 FSLA++ A A FG FTP TWLI +++A+PG W Sbjct: 362 GFSLAYSLATATFGGFTPAVCTWLIHTLDNRAAPGIW 398 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 279 bits (714), Expect = 9e-75, Method: Compositional matrix adjust. Identities = 160/431 (37%), Positives = 240/431 (55%), Gaps = 3/431 (0%) Query: 13 SRINAILRATSGNFLEQFDFFLFGFYASAIGKAFFPSDNETASLLNTFGVFWLGALMRPV 72 SR + A GN LE +DF ++GF +S I + FFPS +E SLL F +G MRPV Sbjct: 9 SRTRQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFGVGFFMRPV 68 Query: 73 GAIVLGAYIDRIGRRQGLIITLSIMAVGTVIIAFCPSYATIGIAAPIIVLAGRLLQGFSA 132 G ++LG Y DR GR+ + + + +M + +IAF P+YA IG+ AP++++ R+LQGF+ Sbjct: 69 GGVLLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARMLQGFAT 128 Query: 133 GVEVGGVSVYLAEIATPGNRGFYTSFQSSSQQVAIFVAAIVGYLLNESMPLEAVASWGWR 192 G E + +L E A P RG Y S+Q Q +A+F A +G L+ + EA+ SWGWR Sbjct: 129 GGEYASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEALESWGWR 188 Query: 193 IPFFLGCLIIPLIFFLRRTLEETPEFLAMKKHPTAREVFASALVHW-HTVVLGMMMAILT 251 +PF G LI P+ ++RR + ET FL + P R+ L + +V++ M + ++ Sbjct: 189 VPFLFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQGLLGVLREYRRSVLVSMGLTVVG 248 Query: 252 TTTFYFVTVYAPTFGKTVLKLSTQDALLVTLLVAVTNFIWNPIGGTVSDRIGRKPVLLAI 311 T +FY V V PTF L L + +V + + P+ G +SDR+GR+PVLL + Sbjct: 249 TVSFYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRRPVLL-V 307 Query: 312 AGLALM-TAYPALSWLVSAPSFGKLLAVAMMFSFYFGTYSGTMLGALVEIVPAHVRTTCF 370 A LA M YP +W+ +APS G+LL + ++ G + G A+ E P VR+T Sbjct: 308 ATLAFMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRVRSTGL 367 Query: 371 SLAFAFAAALFGTFTPLASTWLIERTNDKASPGFWLMFAAALGIIAVLTIYRGTPKPSRA 430 ++A+ A LFG F P TWL E +P F+++ AA LG++A L + G R Sbjct: 368 AVAYNLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYLREGATPAPRP 427 Query: 431 EKPSLRKSPES 441 +P+L K S Sbjct: 428 REPALGKPARS 438