BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0181.0001.p (811 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC0594 [NT] COG0643 Chemotaxis protein histidine kinase and rela... 611 e-174 Cj0284c_1 [NT] COG0643 Chemotaxis protein histidine kinase and r... 354 5e-97 HP0392_1 [NT] COG0643 Chemotaxis protein histidine kinase and re... 333 8e-91 jhp0989_1 [NT] COG0643 Chemotaxis protein histidine kinase and r... 324 4e-88 BS_cheA [NT] COG0643 Chemotaxis protein histidine kinase and rel... 315 2e-85 >CC0594 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Ccr Caulobacter vibrioides Length = 764 Score = 611 bits (1575), Expect = e-174, Method: Compositional matrix adjust. Identities = 324/605 (53%), Positives = 426/605 (70%), Gaps = 8/605 (1%) Query: 72 ERPLRPGEVSLDELERAFRETETEVA-APAPAAK-PAAEPAEAVKKPARKAAGEDVQEGD 129 ER LRPGEVSL+ELE AF E V APAP + P+A A +P + + + + Sbjct: 149 ERTLRPGEVSLEELEAAFLAAEGPVFDAPAPPVETPSAASPAATFEPDQTDSAPEALVSE 208 Query: 130 KIANQSIRVNVDTLEHLMTMVSELVLTRNQLLEISRRNEDTEFKVPLQRLSNVTAELQEG 189 + Q+IRV VD LE +MT+VSELVLTRNQLL+++R D F PLQRLS++T ELQ+ Sbjct: 209 SLGPQTIRVGVDVLEDMMTLVSELVLTRNQLLQLNRGRGDETFTPPLQRLSSITGELQDS 268 Query: 190 VMKTRMQPIGNAWQKLPRIVRDLSGELGKQIELEMHGADTELDRQVLDLIKDPLTHMVRN 249 VMKTRMQPIG AW+KLPR+VRDLSGELGK IEL M G TELDRQVL+ I+DPLTHMVRN Sbjct: 269 VMKTRMQPIGQAWKKLPRLVRDLSGELGKPIELVMEGEATELDRQVLEQIRDPLTHMVRN 328 Query: 250 SADHGLETTAERVAAGKPEQGTIRLSAYHEGGHIIICIADNGRGLNTERIKTKALQNGLV 309 SADHGLE R AAGKPE G I LSAYHEGG I+I + D+GRGL+T RI+ KA++ G+V Sbjct: 329 SADHGLEGPEARRAAGKPEAGLIHLSAYHEGGAIVIRLRDDGRGLDTARIREKAIEKGIV 388 Query: 310 TEAELEKMTEAQIHKFIFAPGFSTAAQVTSVSGRGVGMDVVRTNIDQIGGTIDIKSVAGE 369 AE E MTEAQ+H+ IFAPGFSTAA VT+VSGRGVGMDVVR+NI+QIGG I+++S G+ Sbjct: 389 GRAEAETMTEAQVHRLIFAPGFSTAAVVTNVSGRGVGMDVVRSNIEQIGGQIELQSTLGQ 448 Query: 370 GASVTIKIPLTLAIVSALIVEAGGDRFAIPQLSVVELVRARANSEHRIERIKDTAVLRLR 429 G VT+KIPLTLAIVSALI+ A G+RFA+PQ SV ELV+ A+S+HR E I+ +LRLR Sbjct: 449 GCVVTVKIPLTLAIVSALIIRAAGERFAVPQASVQELVKVSADSDHRFEEIEHVRMLRLR 508 Query: 430 NKLLPLIHLKKLLKIDDGATSTDAENGFIVVTQVGSQTFGIVVDGVFHTEEIVVKPMSTK 489 +L+PLI L + L E F+++ +VG+ FG++V+ V TEEIVVKP+++ Sbjct: 509 EQLIPLIDLSEEL-----GRERRHEAKFVLIMRVGAHRFGVLVEEVIDTEEIVVKPLASV 563 Query: 490 LRHIDMFSGNTILGDGAVIMIIDPNGIAKALGASGSSAHDLADDSASAHANSGEQLTSLL 549 LR I +FSG T+LGDG+V++IIDPNG++ G + A D++A +L SLL Sbjct: 564 LRTIPVFSGATLLGDGSVVLIIDPNGLSDRAGDMPARAQKAIDEAAVWTEAEAAELVSLL 623 Query: 550 VFRAGSSQPKAVPLGLVTRLEEIATDKIELSNGRYMVQYREQLMPLVQM-AGVEVQNQGS 608 + R G+ KAV L +TRLE++ I+ R V YR +LMP++ + G GS Sbjct: 624 IVRVGAGALKAVELSRITRLEQVPVATIQSIGDRAAVDYRGKLMPVLTIEEGQRFVESGS 683 Query: 609 QPILVFADDGRSMGLVVDEIIDIVEERLNIEVAGSQDGILGSAVIKGQATEVIDVGHFLP 668 QP+LV +MGL VD+I+D+V +L+IE+ S+ G+ G A++ G+ATE++D+ HF+ Sbjct: 684 QPLLVVQGMLYAMGLAVDQIVDVVGAKLDIELTASRPGVRGVALVNGRATELLDLDHFML 743 Query: 669 MAFAD 673 +A A+ Sbjct: 744 LALAE 748 >Cj0284c_1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Cje Campylobacter jejuni Length = 622 Score = 354 bits (909), Expect = 5e-97, Method: Compositional matrix adjust. Identities = 213/494 (43%), Positives = 303/494 (61%), Gaps = 31/494 (6%) Query: 38 PVQAAXAAEEDVPV--VEAPSVQAAMTEGTLVVQTL---------ERPLRPGEVSLDELE 86 PV A + E+ +P +EAP + A E + V L ER L+ + D+ Sbjct: 133 PVVATDSNEKSIPQAELEAPKQEIATPEPEVDVNQLSDSEVEAEIERLLKVRKAE-DQAR 191 Query: 87 RAFRETETEVAAPAPAAKPAAEPAEAVKKPARKAAGEDVQEGDKIANQSIRVNVDTLEHL 146 RA ++ +T AAP P A +P E+ +K A+G + D Q+IRV V L+HL Sbjct: 192 RA-QKKQTTNAAPKPTNNTANKPTESGEKKV-PASGSNASSMD----QTIRVEVKRLDHL 245 Query: 147 MTMVSELVLTRNQLLEI----SRRNEDTEFKVPLQR----LSNVTAELQEGVMKTRMQPI 198 M ++ ELVL +N+LL+I R E +F L + LS + ++Q VMKTRMQPI Sbjct: 246 MNLIGELVLGKNRLLKIYDDVEERYEGEKFLEELNQVVSQLSIIITDVQLAVMKTRMQPI 305 Query: 199 GNAWQKLPRIVRDLSGELGKQIELEMHGADTELDRQVLDLIKDPLTHMVRNSADHGLETT 258 + K PR+VRDLS ELGKQIELE+ G +TELD+ +++ I DP+ HM+RNS DHG+E Sbjct: 306 AKVFNKFPRVVRDLSRELGKQIELEITGEETELDKSIVEEIGDPIMHMIRNSCDHGVEDP 365 Query: 259 AERVAAGKPEQGTIRLSAYHEGGHIIICIADNGRGLNTERIKTKALQNGLVTEAELEKMT 318 A R A GKPE+G ++L AY+EG HI++ I D+G+GL+ +K KA++ L+TE E ++MT Sbjct: 366 ATRAANGKPEKGIVQLKAYNEGNHIVVEITDDGKGLDPNGLKAKAIEKNLITEREADQMT 425 Query: 319 EAQIHKFIFAPGFSTAAQVTSVSGRGVGMDVVRTNIDQIGGTIDIKSVAGEGASVTIKIP 378 + + IF PGFSTAA+VT+VSGRGVGMDVV+TNI+++ G I+I S G+G+S +KIP Sbjct: 426 DKEAFALIFKPGFSTAAKVTNVSGRGVGMDVVKTNIEKLNGVIEIDSELGKGSSFKLKIP 485 Query: 379 LTLAIVSALIVEAGGDRFAIPQLSVVELVRARANSEHRIERIKDTAVLRLRNKLLPLIHL 438 LTLAI+ +L+V + +AIP SV+E VR + + IE VLRLR+++L L+ L Sbjct: 486 LTLAIIQSLLVGTQEEFYAIPLASVLETVRVPIDDIYTIE---GKNVLRLRDEVLSLVRL 542 Query: 439 KKLLKIDDGATSTDAENGFIVVTQVGSQTFGIVVDGVFHTEEIVVKPMSTKLRHIDMFSG 498 + + S D ++VV V GI+VD + EEIV+K M L++I +G Sbjct: 543 SDVFGVKQVLESGD--QTYVVVIGVAESKLGIIVDTLVGQEEIVIKSMGDYLQNIQGIAG 600 Query: 499 NTILGDGAVIMIID 512 TI GDG V +IID Sbjct: 601 ATIRGDGRVTLIID 614 >HP0392_1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Hpy Helicobacter pylori 26695 Length = 651 Score = 333 bits (855), Expect = 8e-91, Method: Compositional matrix adjust. Identities = 188/483 (38%), Positives = 288/483 (59%), Gaps = 20/483 (4%) Query: 41 AAXAAEEDVPVVEAPSVQAAMTEGTLVVQTLERPLRPGEVSLDELERAFRETETEVAAPA 100 A D P+ + P + A V +ER L + E ++ R + + A P Sbjct: 170 TAENTSSDNPLADEPDLDYANMSAEEVEAEIERLLNKRQ----EADKERRAQKKQEAKPK 225 Query: 101 PAAKPAAEPAEAVKKPARKAAGEDVQEGDKIA---NQSIRVNVDTLEHLMTMVSELVLTR 157 P E +A K + A D +E + Q++RV+V L+HLM ++ ELVL + Sbjct: 226 QEVTPTKETPKAPKTETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELVLGK 285 Query: 158 NQLL----EISRRNEDTEFKVPLQR----LSNVTAELQEGVMKTRMQPIGNAWQKLPRIV 209 N+L+ ++ R + +F L + +S VT +LQ VMKTRMQP+G + K PR+V Sbjct: 286 NRLIRIYSDVEERYDGEKFLEELNQVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFPRMV 345 Query: 210 RDLSGELGKQIELEMHGADTELDRQVLDLIKDPLTHMVRNSADHGLETTAERVAAGKPEQ 269 RDLS ELGK IEL + G +TELD+ +++ I DPL H++RNS DHG+E ER KPE Sbjct: 346 RDLSRELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRKLNKPET 405 Query: 270 GTIRLSAYHEGGHIIICIADNGRGLNTERIKTKALQNGLVTEAELEKMTEAQIHKFIFAP 329 G ++LSAY+EG HI+I I+D+G+GL+ +K KA++ G+++E + E M++ + IF P Sbjct: 406 GKVQLSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAEGMSDREAFNLIFKP 465 Query: 330 GFSTAAQVTSVSGRGVGMDVVRTNIDQIGGTIDIKSVAGEGASVTIKIPLTLAIVSALIV 389 GFSTA V++VSGRGVGMDVV+TNI+++ G I+I S G G + +KIPLTLAI+ AL+V Sbjct: 466 GFSTAKVVSNVSGRGVGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQALLV 525 Query: 390 EAGGDRFAIPQLSVVELVRARANSEHRIERIKDTAVLRLRNKLLPLIHLKKLLKIDDGAT 449 + +AIP SV+E VR S+ I + +VLRLR+++L L+ L + K+D A Sbjct: 526 GVQEEYYAIPLSSVLETVRI---SQDEIYTVDGKSVLRLRDEVLSLVRLSDIFKVD--AI 580 Query: 450 STDAENGFIVVTQVGSQTFGIVVDGVFHTEEIVVKPMSTKLRHIDMFSGNTILGDGAVIM 509 + ++V+ + Q G++VD + EE+V+K + L++ +G T+ GDG + + Sbjct: 581 LESNSDVYVVIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGKITL 640 Query: 510 IID 512 I+D Sbjct: 641 IVD 643 >jhp0989_1 [NT] COG0643 Chemotaxis protein histidine kinase and related kinases jHp Helicobacter pylori J99 Length = 663 Score = 324 bits (831), Expect = 4e-88, Method: Compositional matrix adjust. Identities = 191/486 (39%), Positives = 290/486 (59%), Gaps = 28/486 (5%) Query: 48 DVPVVEAPSVQAAMTEGTLVVQTLERPLRPGEVSLDELERAFRETETEVAAPAPAAKPAA 107 D P+ + P + A V +ER L + + D+ RA ++ E + A P PA Sbjct: 177 DNPLADEPDLDYANMSAEEVEAEIERLLNKRQEA-DKERRAQKKQEDQ-AKPKQEVAPAK 234 Query: 108 E--PAEAVKKPARKA--------AGEDVQEGDKIA---NQSIRVNVDTLEHLMTMVSELV 154 E E K RK A D +E + Q++RV+V L+HLM ++ ELV Sbjct: 235 ETPKTETPKTETRKVPKAETKAKAKADTEENKAPSIGVEQTVRVDVRRLDHLMNLIGELV 294 Query: 155 LTRNQLL----EISRRNEDTEFKVPLQR----LSNVTAELQEGVMKTRMQPIGNAWQKLP 206 L +N+L+ ++ R + +F L + +S VT +LQ VMKTRMQP+G + K P Sbjct: 295 LGKNRLIRIYSDVEERYDGEKFLEELNQVVSSISAVTTDLQLAVMKTRMQPVGKVFNKFP 354 Query: 207 RIVRDLSGELGKQIELEMHGADTELDRQVLDLIKDPLTHMVRNSADHGLETTAERVAAGK 266 R+VRDLS ELGK IEL + G +TELD+ +++ I DPL H++RNS DHG+E ER K Sbjct: 355 RMVRDLSRELGKSIELIIEGEETELDKSIVEEIGDPLIHIIRNSCDHGIEPLEERRRLNK 414 Query: 267 PEQGTIRLSAYHEGGHIIICIADNGRGLNTERIKTKALQNGLVTEAELEKMTEAQIHKFI 326 PE G ++LSAY+EG HI+I I+D+G+GL+ +K KA++ G+++E + E M++ + I Sbjct: 415 PETGKVQLSAYNEGNHIVIKISDDGKGLDPVMLKEKAIEKGVISERDAESMSDREAFNLI 474 Query: 327 FAPGFSTAAQVTSVSGRGVGMDVVRTNIDQIGGTIDIKSVAGEGASVTIKIPLTLAIVSA 386 F PGFST V++VSGRGVGMDVV+TNI+++ G I+I S G G + +KIPLTLAI+ A Sbjct: 475 FKPGFSTRKVVSNVSGRGVGMDVVKTNIEKLNGIIEIDSEVGVGTTQKLKIPLTLAIIQA 534 Query: 387 LIVEAGGDRFAIPQLSVVELVRARANSEHRIERIKDTAVLRLRNKLLPLIHLKKLLKIDD 446 L+V + +AIP SV+E VR S+ I + +VLRLR+++L L+ L + K+D Sbjct: 535 LLVGVQEEYYAIPLSSVLETVRI---SQDEIYTVDGKSVLRLRDEVLSLVRLSDIFKVD- 590 Query: 447 GATSTDAENGFIVVTQVGSQTFGIVVDGVFHTEEIVVKPMSTKLRHIDMFSGNTILGDGA 506 A + ++V+ + Q G++VD + EE+V+K + L++ +G T+ GDG Sbjct: 591 -AILESNSDVYVVIIGLADQKIGVIVDYLIGQEEVVIKSLGYYLKNTRGIAGATVRGDGK 649 Query: 507 VIMIID 512 + +I+D Sbjct: 650 ITLIVD 655 >BS_cheA [NT] COG0643 Chemotaxis protein histidine kinase and related kinases Bsu Bacillus subtilis Length = 671 Score = 315 bits (808), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 170/420 (40%), Positives = 264/420 (62%), Gaps = 14/420 (3%) Query: 98 APAPAAKPAAEPAEAVKKPARKAAGEDVQEGDKIANQSIRVNVDTLEHLMTMVSELVLTR 157 +PA AA PA E E K+PA+ G +++IRVN+D L+ LM + ELV+ R Sbjct: 263 SPA-AAVPANE--EKQKQPAKNDEQAKHSAG---GSKTIRVNIDRLDSLMNLFEELVIDR 316 Query: 158 NQLLEISRRNEDTEFKVPLQRLSNVTAELQEGVMKTRMQPIGNAWQKLPRIVRDLSGELG 217 +L +I++ E E ++R++ ++ +LQ ++ RM P+ + + PR++R L EL Sbjct: 317 GRLEQIAKELEHNELTETVERMTRISGDLQSIILNMRMVPVETVFNRFPRMIRQLQKELN 376 Query: 218 KQIELEMHGADTELDRQVLDLIKDPLTHMVRNSADHGLETTAERVAAGKPEQGTIRLSAY 277 K+IEL + GA+TELDR V+D I DPL H++RNS DHG+E R+ GKPE G + L AY Sbjct: 377 KKIELSIIGAETELDRTVIDEIGDPLVHLIRNSIDHGIEAPETRLQKGKPESGKVVLKAY 436 Query: 278 HEGGHIIICIADNGRGLNTERIKTKALQNGLVTEAELEKMTEAQIHKFIFAPGFSTAAQV 337 H G H+ I + D+G GLN ++I K L+ ++TE E E + + QI++ IFAPGFSTA Q+ Sbjct: 437 HSGNHVFIEVEDDGAGLNRKKILEKPLER-VITEKEAETLEDNQIYELIFAPGFSTADQI 495 Query: 338 TSVSGRGVGMDVVRTNIDQIGGTIDIKSVAGEGASVTIKIPLTLAIVSALIVEAGGDRFA 397 + +SGRGVG+DVV+ ++ +GG++ +KS G+G+ +I++PLTL+I+S L+++ + FA Sbjct: 496 SDISGRGVGLDVVKNKLESLGGSVSVKSAEGQGSLFSIQLPLTLSIISVLLIKLEEETFA 555 Query: 398 IPQLSVVEL-VRARANSEHRIERIKDTAVLRLRNKLLPLIHLKKLLKIDDGATSTDAENG 456 IP S++E V R + I + D V+ R ++P+++LK+ KI+D T DAE Sbjct: 556 IPISSIIETAVIDRKD----ILQTHDREVIDFRGHIVPVVYLKEEFKIED--TRKDAEQL 609 Query: 457 FIVVTQVGSQTFGIVVDGVFHTEEIVVKPMSTKLRHIDMFSGNTILGDGAVIMIIDPNGI 516 I+V + G + VVD +E+V+K + L ++ SG TILGDG V +IID N + Sbjct: 610 HIIVVKKGDKPTAFVVDSFIGQQEVVLKSLGDYLTNVFAISGATILGDGEVALIIDCNAL 669