BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0177.0018.p         (184 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

aq_844 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolase...    70   4e-12
lin0808 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolas...    65   6e-11
XF0352 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolase...    65   1e-10
ML0491 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolase...    64   2e-10
Rv2583c [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolas...    62   7e-10

>aq_844 [TK] COG0317 Guanosine polyphosphate
           pyrophosphohydrolases/synthetases Aae Aquifex aeolicus
          Length = 696

 Score = 69.7 bits (169), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 46/126 (36%), Positives = 67/126 (53%), Gaps = 13/126 (10%)

Query: 8   VSEAAELAARRHNGMARKGRGSEPYINHLAEVANLLAQVTDGADAELVAAGWLHDTIEDT 67
           +  A E A  +H    RK    EPYI H   VA  LA++  G D E + A  LHDT+EDT
Sbjct: 27  IQRAYEFAKEKHGEQKRKT--GEPYIIHPLNVALKLAEL--GMDHETIIAALLHDTLEDT 82

Query: 68  ETTREELAQKFSARVADLVVECTDDMSLAKLVRRQKQIED------APHKSPDAKLIKTA 121
           +TT EE+ ++F  RVA LV   T    + K+  + +Q E+      A  + P   L+K +
Sbjct: 83  DTTYEEIKERFGERVAKLVEGVT---KIGKIKYKSEQAENYRKLILATAEDPRVILLKLS 139

Query: 122 DKISNI 127
           D++ N+
Sbjct: 140 DRLDNV 145


>lin0808 [TK] COG0317 Guanosine polyphosphate
           pyrophosphohydrolases/synthetases Lin Listeria innocua
          Length = 180

 Score = 65.5 bits (158), Expect = 6e-11,   Method: Compositional matrix adjust.
 Identities = 54/177 (30%), Positives = 82/177 (46%), Gaps = 14/177 (7%)

Query: 7   IVSEAAELAARRHNGMARKGRGSEPYINHLAEVANLLAQVTDGADAELVAAGWLHDTIED 66
           +  +A ++    H+G  RK  G EPY +H   VA +L +   G   E+V AG LHD +ED
Sbjct: 1   MYEKARQMMIEAHSGQVRKITG-EPYFSHPLNVARILRRA--GFREEVVVAGLLHDAVED 57

Query: 67  TETTREELAQKFSARVADLVVECTDDMSLAKLVRRQKQIEDAPHKSPDAKLIKTADKISN 126
           TE T  ++   F   VADLV   T++ +L+   R+   IE     S + K +  ADK+ N
Sbjct: 58  TEMTDADIRATFGDEVADLVASHTENKTLSWEERKAHTIEQVRTGSLEEKALIVADKLDN 117

Query: 127 IGARIVPHPSKDERDDLADY-------AAWADQVVAGC--RGINPRLDRIFDDTIAR 174
           + +  V +    E   +  Y         W ++ +      G+NP     F D  AR
Sbjct: 118 LTS--VKYALSSEGKSVWGYFKRGYELQKWYNEGIKNNMEYGLNPSDVPSFFDEYAR 172


>XF0352 [TK] COG0317 Guanosine polyphosphate
           pyrophosphohydrolases/synthetases Xfa Xylella fastidiosa
           9a5c
          Length = 735

 Score = 64.7 bits (156), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 56/145 (38%), Positives = 75/145 (51%), Gaps = 15/145 (10%)

Query: 19  HNGMARKGRGSEPYINHLAEVANLLAQVTDGADAELVAAGWLHDTIEDTETTREELAQKF 78
           H G  RK    EPYI H   VA +LA +  G D E + A  LHDTIEDT  TRE LA +F
Sbjct: 66  HAGQTRKS--GEPYITHPVAVACVLADL--GMDVETLIAAILHDTIEDTSVTREILAAEF 121

Query: 79  SARVADLVVECTDDMSLAKLVRRQKQIEDAPHK-----SPDAK--LIKTADKISN---IG 128
              VADLV   T  +   K   RQ+   ++  K     S D +  +IK AD++ N   +G
Sbjct: 122 GETVADLVDGVT-KLDKLKFRNRQEAAAESFRKMLLAMSRDLRVIMIKLADRLHNMRTLG 180

Query: 129 ARIVPHPSKDERDDLADYAAWADQV 153
           A+ +   S+  R+ L  YA  A ++
Sbjct: 181 AQSIEARSRIARETLEIYAPIAQRL 205


>ML0491 [TK] COG0317 Guanosine polyphosphate
           pyrophosphohydrolases/synthetases Mle Mycobacterium
           leprae
          Length = 787

 Score = 63.9 bits (154), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 50/139 (35%), Positives = 72/139 (51%), Gaps = 10/139 (7%)

Query: 7   IVSEAAELAARRHNGMARKGRGSEPYINHLAEVANLLAQVTDGADAELVAAGWLHDTIED 66
           IV  A E+A +RH    R  R  +PYI H   VAN+LA++  G D   + A  LHDT+ED
Sbjct: 79  IVQRAFEVADQRHASQLR--RSGDPYITHPLAVANILAEL--GMDITTLVAALLHDTVED 134

Query: 67  TETTREELAQKFSARVADLV--VECTDDMSLAKLVRRQ--KQIEDAPHKSPDAKLIKTAD 122
           T  T E L+++F   V  LV  V   D + L      +  +++  A  + P   +IK AD
Sbjct: 135 TGYTLEALSEEFGDEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMARDPRVLVIKVAD 194

Query: 123 KISNI-GARIVPHPSKDER 140
           ++ N+   R +P P K  R
Sbjct: 195 RLHNMRTMRFLP-PEKQAR 212


>Rv2583c [TK] COG0317 Guanosine polyphosphate
           pyrophosphohydrolases/synthetases Mtu Mycobacterium
           tuberculosis H37Rv
          Length = 790

 Score = 62.0 bits (149), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 48/139 (34%), Positives = 71/139 (51%), Gaps = 10/139 (7%)

Query: 7   IVSEAAELAARRHNGMARKGRGSEPYINHLAEVANLLAQVTDGADAELVAAGWLHDTIED 66
           I+  A E+A +RH    R+    +PYI H   VAN+LA++  G D   + A  LHDT+ED
Sbjct: 82  ILQRAYEVADQRHASQLRQS--GDPYITHPLAVANILAEL--GMDTTTLVAALLHDTVED 137

Query: 67  TETTREELAQKFSARVADLV--VECTDDMSLAKLVRRQ--KQIEDAPHKSPDAKLIKTAD 122
           T  T E L ++F   V  LV  V   D + L      +  +++  A  + P   +IK AD
Sbjct: 138 TGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMARDPRVLVIKVAD 197

Query: 123 KISNI-GARIVPHPSKDER 140
           ++ N+   R +P P K  R
Sbjct: 198 RLHNMRTMRFLP-PEKQAR 215