BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0175.0010.p (298 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC0400 [IQR] COG1028 Dehydrogenases with different specificities... 410 e-114 mll2413 [IQR] COG1028 Dehydrogenases with different specificitie... 393 e-109 Rv3224 [IQR] COG1028 Dehydrogenases with different specificities... 332 5e-91 MT3321 [IQR] COG1028 Dehydrogenases with different specificities... 332 5e-91 PA2892 [IQR] COG1028 Dehydrogenases with different specificities... 286 4e-77 >CC0400 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 285 Score = 410 bits (1055), Expect = e-114, Method: Compositional matrix adjust. Identities = 193/283 (68%), Positives = 227/283 (80%) Query: 3 SLKGKTLFISGASRGIGLAIALRAARDGANVAIAAKTAEPHPKLKGTIYTAADEVRAAGG 62 SLK KTLF++GASRGIGLAIA+RAARDGANV IAAKTAE HPKL GTIYTAA E+ AGG Sbjct: 2 SLKNKTLFVTGASRGIGLAIAVRAARDGANVVIAAKTAEAHPKLPGTIYTAAKEIEDAGG 61 Query: 63 KALPVLCDIRDEAQVMAAIEQTVAEFGGIDVCVNNASAISLTNSQATDMKRFDLMMGINT 122 KALP++ D+R+E+ V A+++ VA+FGGID+CVNNASAISLT + TDMKR+DLM INT Sbjct: 62 KALPLVVDVREESSVQEAVDKAVAQFGGIDICVNNASAISLTPTLMTDMKRYDLMHQINT 121 Query: 123 RGTFMVSKYCIPHLKKAENPHILMLSPPLDMKTKWFEHSTAYTMAKFGMSMCVLGLAGEL 182 RGTF+ SK CIPHLK AENPH+LMLSPPLDM +WF AYTMAKFGMSMCVLG+A E Sbjct: 122 RGTFLTSKACIPHLKNAENPHVLMLSPPLDMSPRWFGSHVAYTMAKFGMSMCVLGMAEEF 181 Query: 183 KSAGVAVNALWPRTTIATAAVGNLLGGDAMMRASRTPEIMGDAAYAIITRPSREFTGHFC 242 K G+A NALWPRT IATAA+ L G+ +R RTPEIM DAAY I +PSR+F+G+F Sbjct: 182 KPDGIAFNALWPRTGIATAAIQFALTGEEGLRHCRTPEIMADAAYGIFNKPSRDFSGNFL 241 Query: 243 IDDKVLYANGVRDFERYRVDPSVALMSDFFVPDDDVPPPGVTV 285 IDD LY GVRDF+ Y+VDP+ +LM DFFVP+ PPPGV + Sbjct: 242 IDDTFLYGEGVRDFDHYKVDPTASLMPDFFVPESSEPPPGVKI 284 >mll2413 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 288 Score = 393 bits (1010), Expect = e-109, Method: Compositional matrix adjust. Identities = 191/274 (69%), Positives = 220/274 (80%) Query: 3 SLKGKTLFISGASRGIGLAIALRAARDGANVAIAAKTAEPHPKLKGTIYTAADEVRAAGG 62 SLKGKTLFISG SRGIGLAIALRAARDGANV IAAKTAEPHPKL GTIY+AA E+ AGG Sbjct: 2 SLKGKTLFISGGSRGIGLAIALRAARDGANVTIAAKTAEPHPKLPGTIYSAAQEIEQAGG 61 Query: 63 KALPVLCDIRDEAQVMAAIEQTVAEFGGIDVCVNNASAISLTNSQATDMKRFDLMMGINT 122 KALPVLCDIR+EAQV A+ +TV +FGGID+CVNNASAI LT + TDMKR+DLM INT Sbjct: 62 KALPVLCDIREEAQVAEAVAKTVEKFGGIDICVNNASAIQLTGTLQTDMKRYDLMHQINT 121 Query: 123 RGTFMVSKYCIPHLKKAENPHILMLSPPLDMKTKWFEHSTAYTMAKFGMSMCVLGLAGEL 182 RGTF+VSK CIPHLK A+NPHIL L+PPLDMK KWF++ AYTMAKFGMSMC LG++ E Sbjct: 122 RGTFLVSKMCIPHLKLADNPHILNLAPPLDMKAKWFKNHVAYTMAKFGMSMCTLGMSAEF 181 Query: 183 KSAGVAVNALWPRTTIATAAVGNLLGGDAMMRASRTPEIMGDAAYAIITRPSREFTGHFC 242 G+AVN+LWP +TI TAAV NLLGG + SR+P+IM DAA+AI RPSRE +G+F Sbjct: 182 AKDGIAVNSLWPISTIDTAAVRNLLGGATVAAMSRSPDIMADAAHAIFMRPSREASGNFY 241 Query: 243 IDDKVLYANGVRDFERYRVDPSVALMSDFFVPDD 276 ID++VL A GV DF Y + L DFFVPD+ Sbjct: 242 IDEEVLRAEGVTDFSAYAPGATGPLAGDFFVPDE 275 >Rv3224 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mtu Mycobacterium tuberculosis H37Rv Length = 282 Score = 332 bits (852), Expect = 5e-91, Method: Compositional matrix adjust. Identities = 163/280 (58%), Positives = 203/280 (72%), Gaps = 3/280 (1%) Query: 3 SLKGKTLFISGASRGIGLAIALRAARDGANVAIAAKTAEPHPKLKGTIYTAADEVRAAGG 62 SL GKT+FISGASRGIGLAIA RAARDGAN+A+ AKTAEPHPKL GT++TAA E+ AGG Sbjct: 2 SLNGKTMFISGASRGIGLAIAKRAARDGANIALIAKTAEPHPKLPGTVFTAAKELEEAGG 61 Query: 63 KALPVLCDIRDEAQVMAAIEQTVAEFGGIDVCVNNASAISLTNSQATDMKRFDLMMGINT 122 +ALP++ DIRD V +A+ TV +FGGID+CVNNASAI+L + MKRFDLM GI Sbjct: 62 QALPIVGDIRDPDAVASAVATTVEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQV 121 Query: 123 RGTFMVSKYCIPHLKKAENPHILMLSPPLDMKTKWFEHSTAYTMAKFGMSMCVLGLAGEL 182 RGT+ VS+ CIPH+K ENPHIL LSPP+ ++ KW TAY MAK+GM++C LG+A E+ Sbjct: 122 RGTYAVSQACIPHMKGRENPHILTLSPPILLEKKWL-RPTAYMMAKYGMTLCALGIAEEM 180 Query: 183 KSAGVAVNALWPRTTIATAAVGNLLGGDAMMRASRTPEIMGDAAYAIITRPSREFTGHFC 242 ++ G+A N LWPRT +ATAAV NLLGGD M SR PE+ DAAY I+ +P+ E+TG Sbjct: 181 RADGIASNTLWPRTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKPATEYTGKTL 240 Query: 243 IDDKVLYANGVRDFERYRVDPSVALMSDFFVPDDDVPPPG 282 + + VL +GV D Y P L D +V +D PPG Sbjct: 241 LCEDVLVESGVTDLSVYDCVPGATLGVDLWV--EDANPPG 278 >MT3321 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) MtC Mycobacterium tuberculosis CDC1551 Length = 282 Score = 332 bits (852), Expect = 5e-91, Method: Compositional matrix adjust. Identities = 163/280 (58%), Positives = 203/280 (72%), Gaps = 3/280 (1%) Query: 3 SLKGKTLFISGASRGIGLAIALRAARDGANVAIAAKTAEPHPKLKGTIYTAADEVRAAGG 62 SL GKT+FISGASRGIGLAIA RAARDGAN+A+ AKTAEPHPKL GT++TAA E+ AGG Sbjct: 2 SLNGKTMFISGASRGIGLAIAKRAARDGANIALIAKTAEPHPKLPGTVFTAAKELEEAGG 61 Query: 63 KALPVLCDIRDEAQVMAAIEQTVAEFGGIDVCVNNASAISLTNSQATDMKRFDLMMGINT 122 +ALP++ DIRD V +A+ TV +FGGID+CVNNASAI+L + MKRFDLM GI Sbjct: 62 QALPIVGDIRDPDAVASAVATTVEQFGGIDICVNNASAINLGSITEVPMKRFDLMNGIQV 121 Query: 123 RGTFMVSKYCIPHLKKAENPHILMLSPPLDMKTKWFEHSTAYTMAKFGMSMCVLGLAGEL 182 RGT+ VS+ CIPH+K ENPHIL LSPP+ ++ KW TAY MAK+GM++C LG+A E+ Sbjct: 122 RGTYAVSQACIPHMKGRENPHILTLSPPILLEKKWL-RPTAYMMAKYGMTLCALGIAEEM 180 Query: 183 KSAGVAVNALWPRTTIATAAVGNLLGGDAMMRASRTPEIMGDAAYAIITRPSREFTGHFC 242 ++ G+A N LWPRT +ATAAV NLLGGD M SR PE+ DAAY I+ +P+ E+TG Sbjct: 181 RADGIASNTLWPRTMVATAAVQNLLGGDEAMARSRKPEVYADAAYVIVNKPATEYTGKTL 240 Query: 243 IDDKVLYANGVRDFERYRVDPSVALMSDFFVPDDDVPPPG 282 + + VL +GV D Y P L D +V +D PPG Sbjct: 241 LCEDVLVESGVTDLSVYDCVPGATLGVDLWV--EDANPPG 278 >PA2892 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Pae Pseudomonas aeruginosa Length = 274 Score = 286 bits (732), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 144/272 (52%), Positives = 186/272 (68%), Gaps = 1/272 (0%) Query: 3 SLKGKTLFISGASRGIGLAIALRAARDGANVAIAAKTAEPHPKLKGTIYTAADEVRAAGG 62 SL GKTLFI+GASRGIG IALRAARDGAN+ IAAK+AEPHPKL+GTI++ A EV AAGG Sbjct: 2 SLHGKTLFITGASRGIGREIALRAARDGANLVIAAKSAEPHPKLEGTIFSVAAEVEAAGG 61 Query: 63 KALPVLCDIRDEAQVMAAIEQTVAEFGGIDVCVNNASAISLTNSQATDMKRFDLMMGINT 122 +ALP+ D+RDE V AA+ + FGGID VNNA AI L + + KRFDLM INT Sbjct: 62 QALPLQLDVRDEQAVAAAMARAAERFGGIDALVNNAGAIRLVGVEKLEPKRFDLMYQINT 121 Query: 123 RGTFMVSKYCIPHLKKAENPHILMLSPPLDMKTKWFEHSTAYTMAKFGMSMCVLGLAGEL 182 R + S+ +P+L+++ N HIL LSPP+++ +WF YT+ K+GMSM LG+ E Sbjct: 122 RAVLVCSQAALPYLRRSANGHILSLSPPINLAGRWFAQHGPYTVTKYGMSMLTLGMHEEF 181 Query: 183 KSAGVAVNALWPRTTIATAAVGNLLGGDAMMRASRTPEIMGDAAYAIITRPSREFTGHFC 242 ++VNALWP+T IATAA+ LG R +RTP IM DAA+AI+T R +G Sbjct: 182 GKYAISVNALWPKTMIATAAIEFELGSRDAFRRARTPAIMADAAHAILTSEGRSLSGRLL 241 Query: 243 IDDKVLYANGVRDFERYRVDPS-VALMSDFFV 273 +D+++L G DFE+YR DP AL+ D F+ Sbjct: 242 VDEELLRERGQSDFEQYRYDPEGGALVPDLFL 273