BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0173.0006.p (225 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr7968 [L] COG0593 ATPase involved in DNA replication initiatio... 164 1e-40 BMEI1238 [L] COG0593 ATPase involved in DNA replication initiati... 160 2e-39 AGc2114 [L] COG0593 ATPase involved in DNA replication initiatio... 154 1e-37 SMc00617 [L] COG0593 ATPase involved in DNA replication initiati... 154 2e-37 CC1711 [L] COG0593 ATPase involved in DNA replication initiation... 94 2e-19 >mlr7968 [L] COG0593 ATPase involved in DNA replication initiation Mlo Mesorhizobium loti Length = 234 Score = 164 bits (415), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 96/214 (44%), Positives = 129/214 (60%), Gaps = 2/214 (0%) Query: 7 PRQLALALPHEEKLTRDDFLEGPANEAALALIDGWPDWPNRIMLLVGPDGSGKSHLAAIW 66 PRQL L L H +RD+ + N A AL+D WPDWP+ +++L GP GSGK+HLAAIW Sbjct: 9 PRQLPLDLGHGTGYSRDELVVSGTNNQAAALVDRWPDWPSPVVVLAGPAGSGKTHLAAIW 68 Query: 67 AESAGARSTAAHALTAEAVPTALATGALVVEDLRPADFDERAMFHLMNLARQDDAYVLIT 126 A A + A + +++ A AL+ +D+ DE+ +FHL+N R + +L+T Sbjct: 69 RARANAVAVDARRI-GDSIAGLGARPALI-DDVDAGAVDEQGLFHLINAVRGAGSTLLLT 126 Query: 127 ARVPPSAFEIELRDLRSRLRAVPTVTLLPPDDQLFRGLIVKFCADRQMSVDEPLVSYLSN 186 AR PSA+ + L DL SRL+A TV + PDD L G+I K ADRQ+ V+ +V YL Sbjct: 127 ARRFPSAWGVSLPDLASRLKAAATVEIHEPDDLLLAGVITKLFADRQVEVEPHVVQYLVR 186 Query: 187 RIERSYVAVRQAVELLDTEALRLGRPVTRALAAE 220 RIERS + VE LD AL P+TRALAAE Sbjct: 187 RIERSLATAMRVVERLDRTALERKMPITRALAAE 220 >BMEI1238 [L] COG0593 ATPase involved in DNA replication initiation Bme Brucella melitensis Length = 231 Score = 160 bits (406), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 92/223 (41%), Positives = 136/223 (60%), Gaps = 6/223 (2%) Query: 7 PRQLALALPHEEKLTRDDFLEGPANEAALALIDGWPDWPNRIMLLVGPDGSGKSHLAAIW 66 PRQ+ L L H+ R+D + +N AA+ LID WP+W + + +L GP G+GK+HLA IW Sbjct: 5 PRQIPLNLEHQPGYNREDLIVTASNRAAVDLIDRWPNWLSPVTILAGPTGAGKTHLAEIW 64 Query: 67 AESAGARSTAAHALTAEAVPTALATGALVVEDLRPADFDERAMFHLMNLARQDDAY---- 122 A +T EAV +A A ++++++ FDE +FHL+N RQ A Sbjct: 65 RSGTDALLVDPSNITEEAVNSA-AERPVLIDNIGAEAFDETGLFHLINSVRQHAAQGPGP 123 Query: 123 -VLITARVPPSAFEIELRDLRSRLRAVPTVTLLPPDDQLFRGLIVKFCADRQMSVDEPLV 181 +L+T+R+ P+ + ++L DL SRL+A V + PDD L G+I K ADRQ+SV+ +V Sbjct: 124 SLLMTSRLWPANWNVKLPDLASRLKAATVVEIAEPDDMLLSGVIHKLFADRQVSVEPHVV 183 Query: 182 SYLSNRIERSYVAVRQAVELLDTEALRLGRPVTRALAAELLRD 224 SYL +R+ERS ++ Q V+ LD AL +TRALAA++L D Sbjct: 184 SYLVSRMERSLLSAIQIVDRLDRAALEQKSRITRALAAQILAD 226 >AGc2114 [L] COG0593 ATPase involved in DNA replication initiation Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 242 Score = 154 bits (390), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 87/215 (40%), Positives = 125/215 (58%), Gaps = 2/215 (0%) Query: 9 QLALALPHEEKLTRDDFLEGPANEAALALIDGWPDWPNRIMLLVGPDGSGKSHLAAIWAE 68 QL LA H+ R+D L + AA++L+D WP+WP+ +++L GP GSGKSHLA IW Sbjct: 16 QLPLAFSHQSASGREDLLVSASLAAAVSLVDEWPNWPSPVVVLAGPPGSGKSHLANIWKN 75 Query: 69 SAGARSTAAHALTAEAVPTALATGALVVEDLRPADFDERAMFHLMNLARQDDAYVLITAR 128 + AR H A TG ++ ED FD+ +FH++N RQ +L+T+R Sbjct: 76 ISDARDI--HPEAGADAARAAETGPVLFEDADRRGFDDTELFHVINSVRQHGTTLLMTSR 133 Query: 129 VPPSAFEIELRDLRSRLRAVPTVTLLPPDDQLFRGLIVKFCADRQMSVDEPLVSYLSNRI 188 P+A+ + L DLRSRL+AV V PD+ L ++VK ADRQ+ +D+ L+ Y+ NR+ Sbjct: 134 QWPAAWPVTLPDLRSRLKAVTVVETGEPDEGLLAQVLVKLFADRQLYMDDKLIGYIVNRM 193 Query: 189 ERSYVAVRQAVELLDTEALRLGRPVTRALAAELLR 223 ERS + VE +D AL +TR L AE+L Sbjct: 194 ERSLDTAQTIVEQIDHLALSRATRITRPLVAEVLN 228 >SMc00617 [L] COG0593 ATPase involved in DNA replication initiation Sme Sinorhizobium meliloti Length = 229 Score = 154 bits (388), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 88/216 (40%), Positives = 125/216 (57%), Gaps = 2/216 (0%) Query: 9 QLALALPHEEKLTRDDFLEGPANEAALALIDGWPDWPNRIMLLVGPDGSGKSHLAAIWAE 68 QL L H RDD L AA++++D WP WP+ ++++ GP GSGKSHLA IW E Sbjct: 8 QLPLVFGHAPATGRDDLLVSDRLSAAISIVDHWPAWPSPVVIICGPVGSGKSHLAGIWRE 67 Query: 69 SAGARSTAAHALTAEAVPTALATGALVVEDLRPADFDERAMFHLMNLARQDDAYVLITAR 128 A R+ H A ++ ED FD+ A+FH++N RQ+ +L+T+R Sbjct: 68 KA--RAEPIHPFAGSNAADIAAEKPVLFEDADRQGFDDAALFHVINSVRQNGTALLMTSR 125 Query: 129 VPPSAFEIELRDLRSRLRAVPTVTLLPPDDQLFRGLIVKFCADRQMSVDEPLVSYLSNRI 188 + P ++ + L DL+SRL+A V + PDD+L ++ K ADRQ+ VDE LV Y+ R+ Sbjct: 126 LWPMSWPVGLPDLKSRLKAATVVEIGEPDDELLVQVLTKLFADRQLLVDERLVGYVVARM 185 Query: 189 ERSYVAVRQAVELLDTEALRLGRPVTRALAAELLRD 224 ERS A + VE +D AL G TRALAAE+L + Sbjct: 186 ERSLEAAQTIVERIDHLALARGTRPTRALAAEVLEE 221 >CC1711 [L] COG0593 ATPase involved in DNA replication initiation Ccr Caulobacter vibrioides Length = 230 Score = 94.4 bits (233), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 81/219 (36%), Positives = 113/219 (51%), Gaps = 5/219 (2%) Query: 9 QLALALPHEEKLTRDDFLEGPANEAALALIDGWPDWPNRIMLLVGPDGSGKSHLAAIWAE 68 Q L L R+DF P+N A+A +D WPDW ++LVGP G GKSHLA WA Sbjct: 4 QFKLPLASPLTHGREDFAVSPSNGEAVARLDAWPDWAEGRLVLVGPAGCGKSHLARAWAA 63 Query: 69 SAGARSTAAHALTAEAVP-TALATGALVVEDL----RPADFDERAMFHLMNLARQDDAYV 123 +AGA A A +V +AL A++VED + A + A+FH++N+A D V Sbjct: 64 AAGAVVVEAANPDAASVDLSALRGRAVLVEDADRRAQGAAVSDEALFHILNMAGVDGGTV 123 Query: 124 LITARVPPSAFEIELRDLRSRLRAVPTVTLLPPDDQLFRGLIVKFCADRQMSVDEPLVSY 183 L+T R P + E+ DLRSRL A+ + PDD + ++ + A + L Y Sbjct: 124 LLTGRTAPLTWSAEVADLRSRLNALSVAEIAEPDDAVLEAVLRRAFAAAWWKPEPDLYPY 183 Query: 184 LSNRIERSYVAVRQAVELLDTEALRLGRPVTRALAAELL 222 L R+ RS + A LL A R +T+ALA E+L Sbjct: 184 LLARLPRSAAEAQAAAALLAEAAADGRRELTKALAREVL 222