BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0167.0022.p         (237 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SMc01001 [R] COG0705 Uncharacterized membrane protein (homolog o...   103   3e-22
mlr0187 [R] COG0705 Uncharacterized membrane protein (homolog of...    92   1e-18
BMEI0739 [R] COG0705 Uncharacterized membrane protein (homolog o...    92   1e-18
AGc3218 [R] COG0705 Uncharacterized membrane protein (homolog of...    77   2e-14

>SMc01001 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila
           rhomboid) Sme Sinorhizobium meliloti
          Length = 243

 Score =  103 bits (257), Expect = 3e-22,   Method: Compositional matrix adjust.
 Identities = 84/232 (36%), Positives = 105/232 (45%), Gaps = 45/232 (19%)

Query: 3   SHPESPLAPPPEAPREQILTLPPALTAYILLIAAIHL--RVLLPPELENWTIDVFGFIPK 60
           + PE+ +       RE    LPP LT  +  + A+H+    +LP E++   I  F F+P 
Sbjct: 8   TSPETDVDSTDVRSREPAFNLPPGLTGILSFLIAVHVLRTYVLPAEIDQELILNFAFLPV 67

Query: 61  RYDSTLLDITFPGGEGAKVW--TFVTYSLLHANLTHIGFNVLWL---------------- 102
           RY       T P GE   VW  T VTYS LH +  H+ FNV W+                
Sbjct: 68  RY-------TLPLGEQGLVWLWTPVTYSFLHGSWEHLIFNVFWMVAFGAPVVRRIGMARL 120

Query: 103 ------------GSHLLTHEHAIAPMIGASASVSGTMAAAIRFAFVKGSFLSFSRGDAEA 150
                       G H++ H   +A +IGAS  VSG M AA RF F        SR  A  
Sbjct: 121 ALFWCLSAAAAVGLHIIFHWGEMAVVIGASGVVSGLMGAAARFVFSPSG--RISRQFAHL 178

Query: 151 AARVPALSLWRALRNGRVLAFLAIWFGVNILFGATSLSLGGEGASVAWQAHI 202
             R   LS    L N  VL F  IWF  N+L G   LS+GG G SVAW+AHI
Sbjct: 179 NRR---LSFAETLTNRSVLVFTGIWFLTNLLVGFGFLSIGGAG-SVAWEAHI 226


>mlr0187 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila
           rhomboid) Mlo Mesorhizobium loti
          Length = 237

 Score = 92.0 bits (227), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 72/237 (30%), Positives = 106/237 (44%), Gaps = 47/237 (19%)

Query: 11  PPPEAPREQILTLPPALTAYILLIAAIHLRVLLPPELENWTIDVFGFIPKRYDSTLLDIT 70
           PPP   RE +  LPP + A I + AA+ L       L+ + ++    I   YD   + + 
Sbjct: 2   PPPA--REPVFNLPPIVLAVIGICAAVFL-------LQQYVLNDAQQITLLYDGAFIPVL 52

Query: 71  FPGGEGAKVWTFV---TYSLLHANLTHIGFNVLWL---GSHLLT---------------- 108
           + G  G   + F    TY+ +H    HI  N++WL   GS L                  
Sbjct: 53  YTGQYGFDWFLFTRPFTYAFMHGGFAHIAINMVWLAAFGSPLANRLGGLRFALFFAVTGL 112

Query: 109 ---------HEHAIAPMIGASASVSGTMAAAIRFAFVKGSFLSFSRGDAEAAARVPALSL 159
                    H +  AP++GAS ++SG M AA RF F         R   +AA   P L +
Sbjct: 113 ASVALFWAMHPYGEAPLVGASGAISGMMGAAARFGFRT------DRSAGKAAFAGPVLPI 166

Query: 160 WRALRNGRVLAFLAIWFGVNILFGATSLSLGGEGASVAWQAHIGGFLAGLLLFSLFD 216
              +R+  V+ FLA+W  +N+  G    + G +G  +AW+AHIGGF+AG      FD
Sbjct: 167 SLVVRSRGVVVFLAVWMIINLATGLLGFAPGVDG-QIAWEAHIGGFVAGFFGLRWFD 222


>BMEI0739 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila
           rhomboid) Bme Brucella melitensis
          Length = 235

 Score = 91.7 bits (226), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 70/239 (29%), Positives = 111/239 (46%), Gaps = 47/239 (19%)

Query: 17  REQILTLPPALTAYILLIAAIHL--RVLLPPELENWTIDVFGFIPKRYD--STLLDITFP 72
           RE I  +P  + A I L  A+++    +L    +   +  F  IP R+   S  +D    
Sbjct: 7   REPIFNIPGVVIALIGLCVAVYVYQNYILSERQDFEFMMNFALIPARFSMASGFVD---- 62

Query: 73  GGEGAKVWTFVTYSLLHANLTHIGFNVLWLG----------------------------S 104
               A ++TF++YS +H +  HI  N++WL                             +
Sbjct: 63  ---PAVIFTFISYSFMHGSFAHIAVNMIWLAAFGSPLAGRIGAVRMILFWVFTSVVAGLT 119

Query: 105 HLLTHEHAIAPMIGASASVSGTMAAAIRFAFVKGSFLSFSRGDAEAAARVPALSLWRALR 164
           H   H  +++P++GAS ++SG M AA R+ F +   + + R    A    P L +   L 
Sbjct: 120 HYALHPESLSPLVGASGAISGMMGAAARYGFRR---VGYGRRSEFAG---PVLPIGLTLT 173

Query: 165 NGRVLAFLAIWFGVNILFGATSLSLGGEGASVAWQAHIGGFLAGLLLFSLFDPVPRTRD 223
              VL F+ +WF +NI+ G  S   G + +S+AW+AHIGGF+AG     L D  PR+ D
Sbjct: 174 LKPVLIFVGVWFLINIVTGLYSTG-GADFSSIAWEAHIGGFIAGFFGIPLMDR-PRSYD 230


>AGc3218 [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila
           rhomboid) Atu Agrobacterium tumefaciens strain C58
           (Cereon)
          Length = 245

 Score = 77.4 bits (189), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 72/232 (31%), Positives = 91/232 (39%), Gaps = 42/232 (18%)

Query: 2   DSHPESPLAPPPEAPREQILTLPPALTAYI--LLIAAIHLRVLLPPELENWTIDVFGFIP 59
           +  P S    P +     I  LP  L   +  L IA +    LL  E   W I  FGFIP
Sbjct: 7   EQPPVSETPEPKDDTNNPIFNLPGLLVGILAALAIAYVVPAYLLSEEGNGWFIFTFGFIP 66

Query: 60  KRYDSTLLDITFPGGEGAKVWTFVTYSLLHANLTHIGFNVLWLGS--------------- 104
            RY      + F       +WT VTYS LH  + HI FN LWL +               
Sbjct: 67  LRYA-----VPFSQQGLEWLWTPVTYSFLHGGIEHILFNGLWLMAFGAPVLRRIGTVRFV 121

Query: 105 -------------HLLTHEHAIAPMIGASASVSGTMAAAIRFAF-VKGSFLSFSRGDAEA 150
                        H   +   +  +IGAS  VS  M AA RFAF V+G +       A  
Sbjct: 122 LLWCISAAVSAFGHAALNWGDVTVLIGASGVVSALMGAACRFAFPVRGGY------SASF 175

Query: 151 AARVPALSLWRALRNGRVLAFLAIWFGVNILFGATSLSLGGEGASVAWQAHI 202
              +P  S+  AL N  VL F  +W   N+L        G  G  +AW AH+
Sbjct: 176 GHLMPRQSILAALSNRTVLIFTLMWLFGNVLIAIGVPLFGDVGGQIAWDAHV 227