BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0165.0032.p (342 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr3019 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Mlo M... 421 e-117 SMc04019 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Sme ... 417 e-116 AGl2129 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Atu A... 412 e-115 BMEII0018 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Bme... 401 e-111 RSc2643 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Rso R... 288 1e-77 >mlr3019 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Mlo Mesorhizobium loti Length = 353 Score = 421 bits (1083), Expect = e-117, Method: Compositional matrix adjust. Identities = 198/326 (60%), Positives = 237/326 (72%) Query: 17 RVGVLLVNLGTPDTADAAGVRVYLKEFLSDPRVIEDQGLLWKLILNGIILRVRPARKARD 76 +VGVLLVNLGTPD + + YL+EFLSDPRVIE +W IL G++L RP + + Sbjct: 28 KVGVLLVNLGTPDGTEFKPMWRYLREFLSDPRVIELNKAIWYPILYGLVLTTRPKKSGAN 87 Query: 77 YLKIWNTEQNESPLKTITRSQADKLAEAIADHDHVVVDWAMRYGNPSIKERIEALAAQGC 136 Y +IWN E+NESPL+T TR+Q++KLAEA+ D V VDWAMRYGNPS E L AQGC Sbjct: 88 YARIWNQERNESPLRTYTRAQSEKLAEALGDLPDVTVDWAMRYGNPSTASVAERLVAQGC 147 Query: 137 GRLLVVPLYPQYSAATSATVCDEAFRVLAGMRAQPILRVTPPYYDDPDYIEALAVSINAH 196 R+L PLYPQYSA T+AT D+ FR L +R P +R PPYY +P YIEALA SI H Sbjct: 148 DRILSFPLYPQYSATTTATANDQLFRALMKLRRAPAIRSVPPYYAEPVYIEALASSIERH 207 Query: 197 LATLPFQPEIIVASFHGMPKEYVDKGDPYQVQCIATTNALRKRLGLDANGLILTFQSRFG 256 LATL F+PE+++ S+HG+PK Y DKGDPYQ C+ TT LR++LG D LI TFQSRFG Sbjct: 208 LATLDFEPEVVITSYHGIPKPYSDKGDPYQAHCLETTRLLREKLGWDEKKLITTFQSRFG 267 Query: 257 KAEWLQPYTDKTVEKLAKDGVRRIAVVTPGFSADCLETLEEIAQENAEIFRHNGGEQFAA 316 EWLQPYTDKTVEKL KDGV+ IA+V PGFS DC+ETL+EI +E AE F H GG+ FA Sbjct: 268 AQEWLQPYTDKTVEKLGKDGVKSIAIVNPGFSVDCIETLDEIGREAAETFHHAGGKNFAH 327 Query: 317 IPCLNDSDGGMDVIRQLVLRELQGWI 342 IPCLNDS GM VI +V REL GW+ Sbjct: 328 IPCLNDSAEGMTVIEAMVRRELSGWV 353 >SMc04019 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Sme Sinorhizobium meliloti Length = 339 Score = 417 bits (1072), Expect = e-116, Method: Compositional matrix adjust. Identities = 202/326 (61%), Positives = 241/326 (73%) Query: 17 RVGVLLVNLGTPDTADAAGVRVYLKEFLSDPRVIEDQGLLWKLILNGIILRVRPARKARD 76 ++GVLLVNLGTPD D +R YL+EFLSD RVIE L W IL GI+L RP + + Sbjct: 14 KLGVLLVNLGTPDGTDVTSMRRYLREFLSDRRVIEWSRLFWYPILYGIVLNTRPRKVGKA 73 Query: 77 YLKIWNTEQNESPLKTITRSQADKLAEAIADHDHVVVDWAMRYGNPSIKERIEALAAQGC 136 Y IWN + NES L+T TR+QA +AEA VVVDWAMRYG PSI RIEAL GC Sbjct: 74 YELIWNKDLNESWLRTYTRNQAALMAEAFGGQPQVVVDWAMRYGQPSIASRIEALQKAGC 133 Query: 137 GRLLVVPLYPQYSAATSATVCDEAFRVLAGMRAQPILRVTPPYYDDPDYIEALAVSINAH 196 R+LV PLYPQY+AAT+ATV D+AF L MR QP LR PPY+DDP YI+ALA SIN H Sbjct: 134 ERILVFPLYPQYAAATTATVNDKAFEALLKMRWQPALRTVPPYHDDPVYIDALATSINKH 193 Query: 197 LATLPFQPEIIVASFHGMPKEYVDKGDPYQVQCIATTNALRKRLGLDANGLILTFQSRFG 256 LATL ++PE+++ASFHG+PK Y +KGDPY QC T LR++LG + L +TFQSRFG Sbjct: 194 LATLDWEPELVLASFHGIPKSYFEKGDPYYCQCQKTARLLREKLGWPQDRLQVTFQSRFG 253 Query: 257 KAEWLQPYTDKTVEKLAKDGVRRIAVVTPGFSADCLETLEEIAQENAEIFRHNGGEQFAA 316 EWLQPYTD TVE+LAK+GV+RIAV+ PGF +DCLETLEEIA + AE F HNGGE+FA Sbjct: 254 PEEWLQPYTDATVERLAKEGVKRIAVINPGFVSDCLETLEEIAGQAAESFHHNGGEKFAH 313 Query: 317 IPCLNDSDGGMDVIRQLVLRELQGWI 342 IPCLNDS GM V+ +V REL+GW+ Sbjct: 314 IPCLNDSPEGMAVLNHVVRRELEGWL 339 >AGl2129 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 368 Score = 412 bits (1058), Expect = e-115, Method: Compositional matrix adjust. Identities = 194/326 (59%), Positives = 239/326 (73%) Query: 17 RVGVLLVNLGTPDTADAAGVRVYLKEFLSDPRVIEDQGLLWKLILNGIILRVRPARKARD 76 +VGVLLVNLGTPD D +R YL EFLSD RVIE L W IL GI+L RP + + Sbjct: 43 KVGVLLVNLGTPDGTDYWPMRRYLAEFLSDKRVIEWSRLYWYPILYGIVLNKRPQKVGKA 102 Query: 77 YLKIWNTEQNESPLKTITRSQADKLAEAIADHDHVVVDWAMRYGNPSIKERIEALAAQGC 136 Y +IWN E+NES L+T TRSQ + +A A+ D +VVVDWAMRYG PSI RI+AL QGC Sbjct: 103 YEEIWNHERNESYLRTYTRSQGELMAAALKDFPNVVVDWAMRYGQPSIASRIDALKEQGC 162 Query: 137 GRLLVVPLYPQYSAATSATVCDEAFRVLAGMRAQPILRVTPPYYDDPDYIEALAVSINAH 196 ++L+ PLYPQY+A+T+ATV D+AF L +R QP +R PPY+DDP YIE LA S+ H Sbjct: 163 EKILLFPLYPQYAASTTATVNDKAFEHLMKLRWQPAIRTVPPYHDDPAYIEGLAASVKNH 222 Query: 197 LATLPFQPEIIVASFHGMPKEYVDKGDPYQVQCIATTNALRKRLGLDANGLILTFQSRFG 256 LATL ++PE+++ SFHG+P+ Y KGDPY C T LR+ LG ++TFQSRFG Sbjct: 223 LATLDWEPEMLITSFHGIPQSYFKKGDPYYCHCQKTARLLREALGRTEKNFMITFQSRFG 282 Query: 257 KAEWLQPYTDKTVEKLAKDGVRRIAVVTPGFSADCLETLEEIAQENAEIFRHNGGEQFAA 316 EWLQPYTDKTVEKLA +G++RIAV+ PGF +DCLETLEEIA E EIF HNGGE+F Sbjct: 283 PEEWLQPYTDKTVEKLASEGIKRIAVMNPGFVSDCLETLEEIAGEAGEIFLHNGGEKFTH 342 Query: 317 IPCLNDSDGGMDVIRQLVLRELQGWI 342 IPCLNDS GM+V+ ++V RELQGW+ Sbjct: 343 IPCLNDSTEGMNVLEKVVRRELQGWV 368 >BMEII0018 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Bme Brucella melitensis Length = 352 Score = 401 bits (1030), Expect = e-111, Method: Compositional matrix adjust. Identities = 192/326 (58%), Positives = 237/326 (72%) Query: 17 RVGVLLVNLGTPDTADAAGVRVYLKEFLSDPRVIEDQGLLWKLILNGIILRVRPARKARD 76 +VGVLLVNLGTPD +R YL EFLSD RVIE L+W IL GI+L RP R R Sbjct: 27 KVGVLLVNLGTPDGTSYGPMRRYLAEFLSDRRVIEWSRLIWYPILYGIVLNTRPRRSGRL 86 Query: 77 YLKIWNTEQNESPLKTITRSQADKLAEAIADHDHVVVDWAMRYGNPSIKERIEALAAQGC 136 Y +IWN E NESPL+T TR+Q +KLA+A++D +VVVDWAMRYG PSI+ + L QGC Sbjct: 87 YDRIWNHENNESPLRTYTRAQGEKLAKALSDQPNVVVDWAMRYGQPSIESITDRLLQQGC 146 Query: 137 GRLLVVPLYPQYSAATSATVCDEAFRVLAGMRAQPILRVTPPYYDDPDYIEALAVSINAH 196 R+++ PLYPQYSA T+ATV D+ F L R P +R P Y +P YI+ALA S+ H Sbjct: 147 ERIVIFPLYPQYSATTTATVNDKFFEALMKKRFMPAIRTVPSYEAEPVYIDALARSVEKH 206 Query: 197 LATLPFQPEIIVASFHGMPKEYVDKGDPYQVQCIATTNALRKRLGLDANGLILTFQSRFG 256 LATL F+PE+I+ S+HG+PK Y DKGDPY+ QC+ TT LR+RLGL + + TFQSRFG Sbjct: 207 LATLSFKPEVILTSYHGIPKSYSDKGDPYRQQCLETTRLLRERLGLGEDEMRATFQSRFG 266 Query: 257 KAEWLQPYTDKTVEKLAKDGVRRIAVVTPGFSADCLETLEEIAQENAEIFRHNGGEQFAA 316 EWLQPYTD+TV++LAK+GV+ +AV+ PGF ADCLET++EI E AE F NGGE F+ Sbjct: 267 PEEWLQPYTDETVKELAKNGVKSVAVLNPGFVADCLETVDEIGNEAAEEFLENGGENFSH 326 Query: 317 IPCLNDSDGGMDVIRQLVLRELQGWI 342 IPCLNDS+ GM VI LV REL GW+ Sbjct: 327 IPCLNDSEEGMKVIETLVRRELLGWV 352 >RSc2643 [H] COG0276 Protoheme ferro-lyase (ferrochelatase) Rso Ralstonia solanacearum Length = 371 Score = 288 bits (737), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 155/335 (46%), Positives = 200/335 (59%), Gaps = 7/335 (2%) Query: 14 KPERVGVLLVNLGTPDTADAAGVRVYLKEFLSDPRVIEDQGLLWKLILNGIILRVRPARK 73 +P+R +LLVNLGTPD V YL++FLSDPRV+E W ILN +IL +R Sbjct: 13 QPDRTAILLVNLGTPDGTSPREVGRYLRQFLSDPRVVEIPRAAWWFILNVLILPLRSRAS 72 Query: 74 ARDYLKIWNTEQN--ESPLKTITRSQADKLAEAIADHDH-VVVDWAMRYGNPSIKERIEA 130 A Y +W E N SPL + QA L + + H VVV AMRYGNPSI ++ Sbjct: 73 AHKYETVWLREANMTGSPLLVYSERQAHALQQLLDAQGHDVVVACAMRYGNPSIPSVMQT 132 Query: 131 LAAQGCGRLLVVPLYPQYSAATSATVCDEAFRVLAGMRAQPILRVTPPYYDDPDYIEALA 190 L QG R+LV+P+YPQYS T+AT DE FRV+ MR QP LR+ ++D P YI AL Sbjct: 133 LRKQGVERILVLPMYPQYSGTTTATAFDEVFRVMGQMRNQPELRLVKHFHDHPAYINALH 192 Query: 191 VSINA----HLATLPFQPEIIVASFHGMPKEYVDKGDPYQVQCIATTNALRKRLGLDANG 246 + A H A + + ++ SFHG+P+ ++ GDPY C+ T L + LGL Sbjct: 193 QQVGAYWAQHGAPDFARGDKLLLSFHGVPRRTLELGDPYHCACLKTGRLLGEALGLQPGQ 252 Query: 247 LILTFQSRFGKAEWLQPYTDKTVEKLAKDGVRRIAVVTPGFSADCLETLEEIAQENAEIF 306 ++TFQSRFG+AEWLQPYT T+E+L + G R+ V PGF ADCLETLEEIA E F Sbjct: 253 YLVTFQSRFGRAEWLQPYTAPTLEELGRVGTGRVDVFCPGFPADCLETLEEIAMEGQSTF 312 Query: 307 RHNGGEQFAAIPCLNDSDGGMDVIRQLVLRELQGW 341 R GG+ F IPCLNDS+ + + + LQGW Sbjct: 313 RVAGGKDFHYIPCLNDSEPWIAGLADIAQAHLQGW 347