BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0165.0003.p (292 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1768 [GEPR] COG0477 Permeases of the major facilitator superf... 211 2e-54 STM1107 [GEPR] COG0477 Permeases of the major facilitator superf... 199 7e-51 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 197 2e-50 CC2354 [GEPR] COG0477 Permeases of the major facilitator superfa... 190 3e-48 RSp0182 [GEPR] COG0477 Permeases of the major facilitator superf... 189 9e-48 >YPO1768 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 211 bits (537), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 113/287 (39%), Positives = 168/287 (58%), Gaps = 8/287 (2%) Query: 1 MAAAPLSTVLGSPVSGALLEMDGMLGFKGWQWLFVLEAVPAVLLGFVVLGFLTDRPEQAR 60 M A P++ LGS VSG +L +DG L +GWQWLF+LE P+VLLG VV +L D P++AR Sbjct: 165 MVAMPVTMALGSLVSGYILALDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKAR 224 Query: 61 WLADDERAWLVKTMKAETDGKATTASH------SIWRGLADPRVLALALVYFGTSAGLYT 114 WL +++ L + ++++ A A + ++WR + P VL L YF + L Sbjct: 225 WLTKEDKQCLQEMLESDRLQLAKQADYGALPQSAMWREIFTPVVLMYTLAYFCLTNTLSA 284 Query: 115 LGVWAPQIIKQFGLSS--IQVGFLNAVPATIAVIAMVLWARHSDRTGERTWHVVLACLMA 172 + +W PQI++ F SS I +G L A+P + M+ W+R SDR ER H VL L A Sbjct: 285 VNIWTPQILQSFNQSSSNITIGLLAAIPQVCTIAGMIWWSRRSDRVQERKMHTVLPYLFA 344 Query: 173 AAGLALAGLWTGLAAVIAALTLVNIGISSSKPPLWSMPTMFLSGSAAAAGIATINSIGNL 232 AAG LA + + + + G ++ W+ P +S A A GIA IN+ GN+ Sbjct: 345 AAGWVLASATQNSVIQLLGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINATGNI 404 Query: 233 GGFVGPAMIGWIRERTGSFDGGLYFVAGLLVLSAVLTLLLSRAQSAP 279 G V P +IGW++++TG+F+ GLYFVAGLLV+ AV+ L++ ++ P Sbjct: 405 GSAVSPVLIGWLKDQTGNFNSGLYFVAGLLVIGAVIFLMIPMKKAPP 451 >STM1107 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 458 Score = 199 bits (506), Expect = 7e-51, Method: Compositional matrix adjust. Identities = 113/293 (38%), Positives = 163/293 (55%), Gaps = 11/293 (3%) Query: 1 MAAAPLSTVLGSPVSGALLEMDGMLGFKGWQWLFVLEAVPAVLLGFVVLGFLTDRPEQAR 60 M A P +T LGS VSG +L +DG+ GWQWLF+LE P+VLLG +V +L D P +A+ Sbjct: 165 MIAMPATTALGSIVSGYILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDDTPAKAK 224 Query: 61 WLADDERAWLVKTMKAET------DGKAT---TASHSIWRGLADPRVLALALVYFGTSAG 111 WL +++ L + M ++ +G + S+WR + P VL L YF + Sbjct: 225 WLTAEDKKCLQEMMDSDRLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTLAYFCLTNT 284 Query: 112 LYTLGVWAPQIIKQF--GLSSIQVGFLNAVPATIAVIAMVLWARHSDRTGERTWHVVLAC 169 L + +W PQI+K F G S+I +G L A+P ++ M+ W+RHSD+ ER H L Sbjct: 285 LSAISIWTPQILKSFNEGSSNITIGLLAAIPQICTILGMIYWSRHSDKHQERKHHTALPF 344 Query: 170 LMAAAGLALAGLWTGLAAVIAALTLVNIGISSSKPPLWSMPTMFLSGSAAAAGIATINSI 229 L AAAG LA + + + + G S+ W+ P +S A A GIA IN+ Sbjct: 345 LFAAAGWLLASATDHNLIQLLGIVMASTGSFSAMAIFWTTPDQSISLRARAIGIAVINAT 404 Query: 230 GNLGGFVGPAMIGWIRERTGSFDGGLYFVAGLLVLSAVLTLLLSRAQSAPAQT 282 GN+G + P MIGW+++ TGSF+ GL+FVA LLV+ A + L+ S P T Sbjct: 405 GNIGSALSPFMIGWLKDITGSFNSGLWFVASLLVVGAAIIWLIPMKASRPRAT 457 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 197 bits (501), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 129/285 (45%), Positives = 180/285 (63%), Gaps = 12/285 (4%) Query: 1 MAAAPLSTVLGSPVSG-ALLEMDGMLGFKGWQWLFVLEAVPAVLLGFVVLGFLTDRPEQA 59 M A LS V+G P+SG AL G+ G GWQW+F++E +P+V++G VL +L +R A Sbjct: 164 MTAVALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHA 223 Query: 60 RWLADDERAWLVKTMKAETDGKATTASHSIWRGLADPRVLALALVYFGTSAGLYTLGVWA 119 RWL D+E+A L + + AE K +I +A PRV ++L+YF GLY + W Sbjct: 224 RWLTDEEKALLTRNIAAEEAQKEDAPIAAI---MASPRVWLMSLIYFSFVMGLYGVSFWL 280 Query: 120 PQIIKQFGLSS-IQVGFLNAVPATIAVIAMVLWARHSDRTGERTWHVVLACLMAAAGLAL 178 P +IKQ G++ + VG L A+P AV+AMVL AR +DRT ER WH+ + L A GL L Sbjct: 281 PTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRTRERRWHIAIPALAGAIGLVL 340 Query: 179 AGLW-TGLAAVIAALTLVNIGISSSKPPLWSMPTMFLSGSAAAAGIATINSIGNLGGFVG 237 + +W T +AALTL +GI ++ P WS+PT FL+G+ AAAGIA INS+GNL GF+ Sbjct: 341 SAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLS 400 Query: 238 PAMIGWIRERTGSFDGGLYFVAGLLVLSAVLTLLLSRAQSAPAQT 282 P +GW+++ T S D G+Y +A +VL A+LTL S PA+T Sbjct: 401 PYAVGWLKDTTRSTDSGMYLLAASMVLGALLTL------SVPART 439 >CC2354 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 430 Score = 190 bits (483), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 106/272 (38%), Positives = 157/272 (57%), Gaps = 1/272 (0%) Query: 1 MAAAPLSTVLGSPVSGALLEMDGMLGFKGWQWLFVLEAVPAVLLGFVVLGFLTDRPEQAR 60 M A+ + +G+ + G LL MDG LG GWQW+F++ PAVLL VL L P AR Sbjct: 149 MIASAFANAVGAAIGGLLLGMDGFLGLAGWQWVFLVTGAPAVLLAPYVLWRLPSGPSDAR 208 Query: 61 WLADDERAWLVKTMKAETDGKATTASHSIWRGLADPRVLALALVYFGTSAGLYTLGVWAP 120 WL D E++WL T+ AE G+ W+ + DPRVL LA +Y G Y L W P Sbjct: 209 WLPDVEKSWLASTLAAERGGEVDD-HRGAWKAIFDPRVLMLAGLYIGMPLSAYGLSYWLP 267 Query: 121 QIIKQFGLSSIQVGFLNAVPATIAVIAMVLWARHSDRTGERTWHVVLACLMAAAGLALAG 180 I+K FG+S+ GF+N +P + +A+ RH+ R G WH+ L+AA L+L+ Sbjct: 268 TIVKSFGVSNTVNGFINVIPWLLVAVALWFVPRHAARHGASAWHIAGPVLLAAVALSLSV 327 Query: 181 LWTGLAAVIAALTLVNIGISSSKPPLWSMPTMFLSGSAAAAGIATINSIGNLGGFVGPAM 240 + G A L + I +++P WS+P FLSG AAAGIATIN++GNLGGF+ + Sbjct: 328 ILPGAALKFTMLCIAAPAIFAAQPVFWSLPPSFLSGPRAAAGIATINAVGNLGGFIAQNL 387 Query: 241 IGWIRERTGSFDGGLYFVAGLLVLSAVLTLLL 272 + +R+ TGS + +A +L+++++L ++ Sbjct: 388 VPVVRDATGSELAPMLALAAVLLVTSLLIFIV 419 >RSp0182 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 453 Score = 189 bits (479), Expect = 9e-48, Method: Compositional matrix adjust. Identities = 116/286 (40%), Positives = 165/286 (57%), Gaps = 3/286 (1%) Query: 2 AAAPLSTVLGSPVSGALLEMDGMLGFKGWQWLFVLEAVPAVLLGFVVLGFLTDRPEQARW 61 AA P+S V+G+P+S +++ L + GW+W+ +LE PAV+ G + G+L DRP+ ARW Sbjct: 167 AAIPVSYVVGAPLSTWIMDHVHWLQWSGWRWMLLLEGAPAVIGGLLCYGYLADRPKDARW 226 Query: 62 LADDERAWLVKTMKAETDGKATTASHSIWRGLADPRVLALALVYFGTSAGLYTLGVWAPQ 121 L++ ER WL+ ++ + + A + + + PRVL LA +YF G +G W PQ Sbjct: 227 LSEAERDWLLAELERDRKARPAAAHLATLKVMTHPRVLYLAFIYFVYQCGSLGIGYWMPQ 286 Query: 122 IIKQF--GLSSIQVGFLNAVPATIAVIAMVLWARHSDRTGERTWHVVLACLMAAAGLALA 179 IIK F LS +VG + +P A M+ W+R SD ER H + +AA A Sbjct: 287 IIKGFSSALSHTEVGLIAMLPYVFATAVMIWWSRRSDLRAERRLHSAVPLGVAALAFVGA 346 Query: 180 GLWTGLAAVIAALTLVNIGISSSKPPLWSMPTMFLSGSAAAAGIATINSIGNLGGFVGPA 239 G A +A L+L G+ + K P W++PT+FL+ S AA IA INS+GNLGGFVGP Sbjct: 347 GFIGHPAVAMAMLSLSLAGLYAFKSPFWALPTLFLTRSTAAVSIAVINSVGNLGGFVGPF 406 Query: 240 MIGWIRERTGSFDGGLYFVAGLLVLSAVLTLLLSRAQSAPAQTEPQ 285 IG+ + + S GL F+AGLL +S V+TL L R A A PQ Sbjct: 407 AIGYFKGQMHSTTAGLLFLAGLLAVSFVMTLRL-RVTEAHAPDRPQ 451