BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0164.0021.p (295 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3467 [GEPR] COG0477 Permeases of the major facilitator superfa... 86 7e-17 AGpA571 [GEPR] COG0477 Permeases of the major facilitator superf... 67 5e-11 RSp0052 [GEPR] COG0477 Permeases of the major facilitator superf... 67 6e-11 ZydjE [GEPR] COG0477 Permeases of the major facilitator superfam... 66 1e-10 ECs2476 [GEPR] COG0477 Permeases of the major facilitator superf... 66 1e-10 >PA3467 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 455 Score = 86.3 bits (212), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 86/290 (29%), Positives = 133/290 (45%), Gaps = 31/290 (10%) Query: 6 WRLLFAIGVLPSVLVLLVRIWVPESPRWLCRQGRYD---------EARKSLAWALQVQPS 56 WR +F + LP+V VL +R +PESPRWL + GR + EAR + L P Sbjct: 176 WRSIFLVLALPAVFVLAIRFLIPESPRWLEQAGRREQADRVLRDIEARVMRSLGLTELPP 235 Query: 57 ELPLPSAADAGPIVTTSWFDLFK--YPRSLIVSWLGNAGAQTGVYGITLWAPALFVLL-L 113 L P + P +++ +L+ Y R + W A G YG+T W AL Sbjct: 236 PLRQPQRERSRPGFFSAFAELWSPAYRRRTLTVWGLWFFALLGFYGLTSWLSALLQQSGF 295 Query: 114 KVTPQEAAKMMILLSVTGFLGRISFSYFSELLGXFGAGALTIIAG----YHYDATLFGMS 169 VT ++ +L+S+ G G + ++ E G + L ++ G Y Y T Sbjct: 296 AVT--QSVYYTVLISLAGIPGFLCAAWLVESWGRKPSCVLMLLGGGAMAYAYGQTAVFGG 353 Query: 170 AFWLLLA---AAFFFADGGFAIVGPYAAEVWPSHLRTTGMGSAYGFGGIGKIIGPVGLAL 226 + LL+ A FF G +A++ Y E++P+ R TG G A G IG ++GP+ L Sbjct: 354 SLALLIGFGLAMQFFLFGMWAVLYTYTPELYPTSARATGSGFASAVGRIGSLLGPLVTGL 413 Query: 227 IVGSNNYLKPDVPLTQIPTAFVYLGCWFLMAGAVYLFFGLETRGKSIEQI 276 + +PLT F F +A V FG+ETRG+++E++ Sbjct: 414 V----------LPLTGQGGVFTLGALCFGVAALVVWAFGIETRGRTLEEL 453 >AGpA571 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 461 Score = 67.0 bits (162), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 68/287 (23%), Positives = 123/287 (42%), Gaps = 30/287 (10%) Query: 6 WRLLFAIGVLPSVLVLLVRIWVPESPRWLCRQGRYDEAR---KSLAWALQVQPSELPLPS 62 W+ +F +G++P++L++ +R ++ ESPRWL GRYDEA K + + + LP P Sbjct: 189 WKAMFIVGLVPAMLMIPLRWFLKESPRWLAATGRYDEANVIVKRMEESARAAGKALPEPR 248 Query: 63 AADAGPIVTTSWFDLFK--YPRSLIVSWLGNAGAQTGVYGITLWAPALFVLLLKVTPQEA 120 + W +LF+ Y + + W A G W P L+ + + + Sbjct: 249 IIATPAKRVSDWRELFQGIYLKRTLSIWAMWFCAYMVANGTITWLPTLYRQTFNLPLETS 308 Query: 121 AKMMILLSVTGFLGRISFSYFSELLG--XFGAGALTII-AGYHYDATLFGMSAFWLLLAA 177 + S G + + + + +G + AGAL + A L S +L+ Sbjct: 309 ILYGFMTSAAGVVAAVICALLIDKVGRKRWYAGALLLAPVPLAILAWLGATSPMQVLI-- 366 Query: 178 AFFFADGGFAIVGP-------YAAEVWPSHLRTTGMGSAYGFGGIGKIIGPVGLALIVGS 230 FA +AIV Y+AE++P+ +R G G+ + +G GP+ + ++ S Sbjct: 367 ---FAGLAYAIVQTVTFSLYLYSAEIYPTRMRAIGTGAGSAWLRLGSSAGPMLVGFVMSS 423 Query: 231 NNYLKPDVPLTQIPTAFVYLGCWFLMAGAVYLFFGLETRGKSIEQID 277 I F ++ V + F +ET+GK +E++ Sbjct: 424 MG----------IQYVFATFAFILIIGAVVTMLFAVETKGKVLEELS 460 >RSp0052 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 476 Score = 66.6 bits (161), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 87/307 (28%), Positives = 135/307 (43%), Gaps = 38/307 (12%) Query: 6 WRLLFAIGVLPSVLVLLVRIWVPESPRWLCRQGRYDEA----RKSLAWALQ-VQPSELPL 60 WR +FA+ +P++ VL+VR VPESPRWL GR +A R A ++ + + LP Sbjct: 181 WRAVFALLAVPAIFVLIVRRAVPESPRWLEHAGRNAQADTVMRGIEAKVMRSLNTTTLP- 239 Query: 61 PSAADAGPIVTTSWFDLFK-----YPRSLIVSWLGNAGAQTGVYGITLWAPALFVLL-LK 114 P + P L + Y R + WL A G YG+T W AL Sbjct: 240 PIVQHSAPQPVRRHSALREIWSAAYRRRTTMVWLLWFFALLGFYGLTSWLGALLQQAGFA 299 Query: 115 VTPQEAAKMMILLSVTGFLGRISFSYFSELLGX--------FGAGALTIIAGYHYDATLF 166 VT ++ +L+S+ G G + ++ E G G GA+ + G + L+ Sbjct: 300 VT--QSVYYTVLISLGGVPGFLCAAWLVERWGRKPTCIASLLGGGAMAYLYG---QSALY 354 Query: 167 GMSAFWLLLA--AAFFFADGGFAIVGPYAAEVWPSHLRTTGMGSAYGFGGIGKIIGPVGL 224 G S L+ A FF G +A++ Y E + + R TG G A G +G +IGP + Sbjct: 355 GGSVTLLICTGLAMQFFLFGMWAVLYTYTPEQYGTGARATGSGFASAIGRVGSLIGPYVV 414 Query: 225 ALIVGSNNYLKPDVPLTQIPTAFVYLGCWFLMAGAVYLFFGLETRGKSIEQIDKELNATA 284 ++ +P+ F F +A G+ETRG ++E + E +A A Sbjct: 415 GVV----------LPVFGQGGVFTLGAISFAVAALAVWALGIETRGLALEALASE-DAAA 463 Query: 285 DVAASAT 291 + A +T Sbjct: 464 ETAPYST 470 >ZydjE [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 416 Score = 65.9 bits (159), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 84/293 (28%), Positives = 121/293 (41%), Gaps = 30/293 (10%) Query: 5 QWRLLFAIGVLPSVLV-LLVRIWVPESPRWLCRQGRYDEARKSLAWALQVQPSE--LPLP 61 WR++F +G + +L L + ESPRWL +G+ A L Q E + LP Sbjct: 138 SWRIMFLLGGIGILLAWFLSGKYFIESPRWLAGKGQIAGAECQLREVEQQIEREKSIRLP 197 Query: 62 ------SAADAGPIVTTSWFDLFK--YPRSLIVSWLGNAGAQTGVYGITLWAPALFV--- 110 S + I T W LFK R +V+ +Y IT+W P +FV Sbjct: 198 PLTSYQSNSKVKVIKGTFWL-LFKGEMLRRTLVAITVLIAMNISLYTITVWIPTIFVNSG 256 Query: 111 LLLKVTPQEAAKMMILLSVTGFLGRISFSYFSELLGXFGAGALTIIA--GYHYDATLFGM 168 + + + A +MI V F+ + +F L FG+ L IIA GY Y Sbjct: 257 IDVDKSILMTAVIMIGAPVGIFIAALIIDHFPRRL--FGSTLLIIIAVLGYIYSIQTTEW 314 Query: 169 SAFWLLLAAAFFFADGGFAIVGPYAAEVWPSHLRTTGMGSAYGFGGIGKIIGPVGLALIV 228 + L FF Y E+WP+HLR G G G I + P G+A ++ Sbjct: 315 AILIYGLVMIFFLYMYVCFASAVYIPELWPTHLRLRGSGFVNAVGRIVAVFTPYGVAALL 374 Query: 229 GSNNYLKPDVPLTQIPTAFVYLGCWFLMAGAVYLFFGLETRGKSIEQIDKELN 281 + T F+ LG L+ V FG+ETR S+E+I E+N Sbjct: 375 THYGSI----------TVFMVLGVMLLLCALVLSIFGIETRKVSLEEIS-EVN 416 >ECs2476 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 416 Score = 65.9 bits (159), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 84/293 (28%), Positives = 121/293 (41%), Gaps = 30/293 (10%) Query: 5 QWRLLFAIGVLPSVLV-LLVRIWVPESPRWLCRQGRYDEARKSLAWALQVQPSE--LPLP 61 WR++F +G + +L L + ESPRWL +G+ A L Q E + LP Sbjct: 138 SWRIMFLLGGIGILLAWFLSGKYFIESPRWLAGKGQIAGAECQLREVEQQIEREKSIRLP 197 Query: 62 ------SAADAGPIVTTSWFDLFK--YPRSLIVSWLGNAGAQTGVYGITLWAPALFV--- 110 S + I T W LFK R +V+ +Y IT+W P +FV Sbjct: 198 PLTSYQSNSKVKVIKGTFWL-LFKGEMLRRTLVAITVLIAMNISLYTITVWIPTIFVNSG 256 Query: 111 LLLKVTPQEAAKMMILLSVTGFLGRISFSYFSELLGXFGAGALTIIA--GYHYDATLFGM 168 + + + A +MI V F+ + +F L FG+ L IIA GY Y Sbjct: 257 IDVDKSILMTAVIMIGAPVGIFIAALIIDHFPRRL--FGSTLLIIIAVLGYIYSIQTTEW 314 Query: 169 SAFWLLLAAAFFFADGGFAIVGPYAAEVWPSHLRTTGMGSAYGFGGIGKIIGPVGLALIV 228 + L FF Y E+WP+HLR G G G I + P G+A ++ Sbjct: 315 AILIYGLVMIFFLYMYVCFASAVYIPELWPTHLRLRGSGFVNAVGRIVAVFTPYGVAALL 374 Query: 229 GSNNYLKPDVPLTQIPTAFVYLGCWFLMAGAVYLFFGLETRGKSIEQIDKELN 281 + T F+ LG L+ V FG+ETR S+E+I E+N Sbjct: 375 THYGSI----------TVFMVLGVMLLLCALVLSIFGIETRKVSLEEIS-EVN 416