BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0163.0012.p (365 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEI1611 [F] COG0167 Dihydroorotate dehydrogenase Bme Brucella m... 363 e-100 AGc861 [F] COG0167 Dihydroorotate dehydrogenase Atu Agrobacteriu... 333 5e-91 CC0528 Non COG 329 8e-90 SMc02245 [F] COG0167 Dihydroorotate dehydrogenase Sme Sinorhizob... 328 2e-89 mll5681 [F] COG0167 Dihydroorotate dehydrogenase Mlo Mesorhizobi... 324 2e-88 >BMEI1611 [F] COG0167 Dihydroorotate dehydrogenase Bme Brucella melitensis Length = 364 Score = 363 bits (933), Expect = e-100, Method: Compositional matrix adjust. Identities = 195/362 (53%), Positives = 249/362 (68%), Gaps = 7/362 (1%) Query: 5 FDAFSLPLLRWFDPEDAHRMAIQGLKLLPPIRQRPDDPKLAVRAFGLNFPNPIGMAAGFD 64 F+ L FD E AH ++I GLK + P+DP L+V+ GL FPNP+GMAAG+D Sbjct: 5 FETLGRRALFTFDAEQAHGLSITGLKTGIVTCRTPEDPALSVKVAGLKFPNPLGMAAGYD 64 Query: 65 KSAEVPDALLRLGFGFVEIGSVTPKPQGGNPRPRLFRLERDEAVINRMGFNNDGAEAVLR 124 K+AEVPDALL+LGFGF E+G++TP+PQ GNPRPR+FRL D+AVINR+GFNN+G EA + Sbjct: 65 KNAEVPDALLKLGFGFAEVGTLTPRPQSGNPRPRIFRLVDDKAVINRLGFNNEGHEAAFK 124 Query: 125 RLAARASAGGIVGVNVGANKDSPDRAADYVKLIETFAPVASYFTVNVSSPNTPGLRNLQQ 184 RL+ RA GIVGVN+GANKD+ DR ADYV I F +A YFTVN+SSPNTPGLRNLQ Sbjct: 125 RLSRRAGKSGIVGVNIGANKDAEDRIADYVAGIRRFYQLARYFTVNISSPNTPGLRNLQA 184 Query: 185 SAALDDLLARVIDTR-ERVRKNAGDSPVLLKIAPDLSLAELDDVVHIARSRRVDGMIVAN 243 AL +LL+RV++ R E PV LKIAPDL+ ELDD+ A ++++DG+IV+N Sbjct: 185 REALHELLSRVLEARDEEGNMCTLKRPVFLKIAPDLTDEELDDIAAEADAQKLDGIIVSN 244 Query: 244 TTLARPSTLREENRAKEQGGLSGRPLFRLSTRMVAETYVRVEGAFPLIGVGGIDSGGAAL 303 TTL+R S L+ + E GGLSG PLF ST ++A RV PLIGVGGIDS AL Sbjct: 245 TTLSR-SGLKNPENSNETGGLSGAPLFERSTVVLARMRERVGPDMPLIGVGGIDSAETAL 303 Query: 304 TKIRAGASLIQLYSSLVYKGLGLVDDIKRDLSSTLLRTGRDSLSEIVGADAATITAEDWP 363 KI+AGA L+QLYS L+Y+G GL +I R LS+ + G S++E+ D ++W Sbjct: 304 AKIKAGADLVQLYSGLIYRGPGLPGEILRGLSTAIKYEGVSSIAELRDRD-----TKEWA 358 Query: 364 VR 365 R Sbjct: 359 AR 360 >AGc861 [F] COG0167 Dihydroorotate dehydrogenase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 364 Score = 333 bits (853), Expect = 5e-91, Method: Compositional matrix adjust. Identities = 182/339 (53%), Positives = 230/339 (67%), Gaps = 4/339 (1%) Query: 13 LRWFDPEDAHRMAIQGLKL-LPPIRQRPDDPKLAVRAFGLNFPNPIGMAAGFDKSAEVPD 71 L DPE AH +++ LK P P DP+L GL FPNP+GMAAG+DK+AEVP Sbjct: 14 LFLIDPEKAHGLSVAALKSGFLPTCMVPHDPRLQQTVAGLVFPNPLGMAAGYDKNAEVPG 73 Query: 72 ALLRLGFGFVEIGSVTPKPQGGNPRPRLFRLERDEAVINRMGFNNDGAEAVLRRLAARAS 131 LLRLGFGF EIG+VTP+ Q GNP+PR+FRL DE VINR+GFNN+G A L RL +A Sbjct: 74 PLLRLGFGFTEIGTVTPRAQSGNPKPRIFRLVEDEGVINRLGFNNEGHAAALERL-TQAR 132 Query: 132 AGGIVGVNVGANKDSPDRAADYVKLIETFAPVASYFTVNVSSPNTPGLRNLQQSAALDDL 191 GIVGVN+GANKDS DR ADYV+ IE F VASYFTVN+SSPNTPGLR+LQ +L L Sbjct: 133 LRGIVGVNIGANKDSEDRIADYVQGIEAFYAVASYFTVNISSPNTPGLRDLQARESLAAL 192 Query: 192 LARVIDTRERVRKNAGDS-PVLLKIAPDLSLAELDDVVHIARSRRVDGMIVANTTLARPS 250 L V++ R+ + G P+ LKIAPDL+ LDDV A + +DG+IV+NTTL+R Sbjct: 193 LTAVLERRKTEAERLGKRIPIFLKIAPDLTEEGLDDVAEEALAHDLDGLIVSNTTLSREG 252 Query: 251 TLREENRAKEQGGLSGRPLFRLSTRMVAETYVRVEGAFPLIGVGGIDSGGAALTKIRAGA 310 LR E GGLSG+PLF LST ++A+ RV P+IGVGG+ S AL K+RAGA Sbjct: 253 -LRPGPHRGEAGGLSGKPLFELSTTVLAKMRRRVGANLPIIGVGGVSSAETALEKVRAGA 311 Query: 311 SLIQLYSSLVYKGLGLVDDIKRDLSSTLLRTGRDSLSEI 349 L+QLYS +VY+G GL I + +S + R G +++ ++ Sbjct: 312 DLVQLYSCMVYEGPGLPSAIVKGMSKLVAREGVETIRDL 350 >CC0528 Non COG Length = 352 Score = 329 bits (843), Expect = 8e-90, Method: Compositional matrix adjust. Identities = 185/342 (54%), Positives = 231/342 (67%), Gaps = 3/342 (0%) Query: 13 LRWFDPEDAHRMAIQGLKL-LPPIRQRPDDPKLAVRAFGLNFPNPIGMAAGFDKSAEVPD 71 L FDPEDAH AI+GLK L P +PDDP LAV+ GL PN +G+AAGFDK+AEVPD Sbjct: 11 LHAFDPEDAHGWAIRGLKWGLGPRDAQPDDPILAVKIAGLELPNCVGLAAGFDKNAEVPD 70 Query: 72 ALLRLGFGFVEIGSVTPKPQGGNPRPRLFRLERDEAVINRMGFNNDGAEAVLRRLAARAS 131 A+L GFGFVE G+VTP Q GNPRPRLFRL D+AVINRMGFNN G E +RLAAR Sbjct: 71 AMLAAGFGFVEAGTVTPLAQAGNPRPRLFRLTEDQAVINRMGFNNGGLEPFAQRLAARQG 130 Query: 132 AGGIVGVNVGANKDSPDRAADYVKLIETFAPVASYFTVNVSSPNTPGLRNLQQSAALDDL 191 GG+VG N+GANKD+ DR DYV + ++ YFT N+SSPNTPGLR LQ AAL++L Sbjct: 131 RGGVVGANIGANKDATDRIQDYVTGLTRLWGLSDYFTANISSPNTPGLRALQTKAALEEL 190 Query: 192 LARVIDTRERVRKNAG-DSPVLLKIAPDLSLAELDDVVHIARSRRVDGMIVANTTLARPS 250 L R+ +TR ++ +G D P+ LK+APDL E++ +V +D +IV+NTT+ARP Sbjct: 191 LGRLAETRAALKVASGADYPIFLKVAPDLEDGEVEAIVETVVGAGLDAIIVSNTTIARPE 250 Query: 251 TLREENRAKEQGGLSGRPLFRLSTRMVAETYVRVEGAFPLIGVGGIDSGGAALTKIRAGA 310 TL+ A E GGLSG PL ST ++A + G LIG GG+ G A KIRAGA Sbjct: 251 TLKSRF-AGESGGLSGAPLLEASTAVLARFHAAAAGRVALIGAGGVADGAGAYAKIRAGA 309 Query: 311 SLIQLYSSLVYKGLGLVDDIKRDLSSTLLRTGRDSLSEIVGA 352 +QLYS+LVY G GLV IKRDL++ L G ++ + +GA Sbjct: 310 RAVQLYSALVYGGPGLVTRIKRDLAARLRADGFAAVEDAIGA 351 >SMc02245 [F] COG0167 Dihydroorotate dehydrogenase Sme Sinorhizobium meliloti Length = 362 Score = 328 bits (840), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 182/339 (53%), Positives = 228/339 (67%), Gaps = 4/339 (1%) Query: 13 LRWFDPEDAHRMAIQGLKL-LPPIRQRPDDPKLAVRAFGLNFPNPIGMAAGFDKSAEVPD 71 L FDPE AH ++I+ LK L P P DP+L GL F NPIGMAAG+DK+AEVP+ Sbjct: 13 LFLFDPEAAHGLSIKALKSGLVPSCAAPADPRLGQTVAGLVFSNPIGMAAGYDKNAEVPE 72 Query: 72 ALLRLGFGFVEIGSVTPKPQGGNPRPRLFRLERDEAVINRMGFNNDGAEAVLRRLAARAS 131 ALL++GFGF EIG+VTP+PQ GN +PRLFRL DEAVINR+GFNN+G A L RL A S Sbjct: 73 ALLKIGFGFTEIGTVTPRPQAGNDKPRLFRLVEDEAVINRLGFNNEGHGAALARLKA-CS 131 Query: 132 AGGIVGVNVGANKDSPDRAADYVKLIETFAPVASYFTVNVSSPNTPGLRNLQQSAALDDL 191 ++GVN+GANKDS DR ADYV I TF VA YFT N+SSPNTPGLR+LQ +L L Sbjct: 132 REALIGVNIGANKDSADRIADYVTGIRTFYAVARYFTANISSPNTPGLRDLQARESLSAL 191 Query: 192 LARVIDTR-ERVRKNAGDSPVLLKIAPDLSLAELDDVVHIARSRRVDGMIVANTTLARPS 250 L+ V+ R + RK PV LKIAPDL+ +DD+ + +DG+IV+NTTL+R Sbjct: 192 LSAVLAARDDEARKGGRQVPVFLKIAPDLTEEGMDDIAAEVLAHGLDGLIVSNTTLSREG 251 Query: 251 TLREENRAKEQGGLSGRPLFRLSTRMVAETYVRVEGAFPLIGVGGIDSGGAALTKIRAGA 310 L++ +A E GGLSG+PLF ST ++A RV P+IGVGG+ S A KIRAGA Sbjct: 252 -LKDRRQANEAGGLSGKPLFEKSTAVLARMRKRVGPHLPIIGVGGVCSAETAAEKIRAGA 310 Query: 311 SLIQLYSSLVYKGLGLVDDIKRDLSSTLLRTGRDSLSEI 349 L+QLYS ++Y+G GL I R LS+ R S+ +I Sbjct: 311 DLVQLYSCMIYEGPGLPGRIVRGLSALCEREKLASIRDI 349 >mll5681 [F] COG0167 Dihydroorotate dehydrogenase Mlo Mesorhizobium loti Length = 359 Score = 324 bits (831), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 174/320 (54%), Positives = 219/320 (68%), Gaps = 5/320 (1%) Query: 5 FDAFSLPLLRWFDPEDAHRMAIQGLKL-LPPIRQRPDDPKLAVRAFGLNFPNPIGMAAGF 63 D LL FDPE AH ++I L+ LP + D +L V GL+FPNP+GMAAG+ Sbjct: 4 LDRLGQKLLFAFDPETAHGLSIAALRCGLPAGTRAVRDIRLKVSLCGLDFPNPLGMAAGY 63 Query: 64 DKSAEVPDALLRLGFGFVEIGSVTPKPQGGNPRPRLFRLERDEAVINRMGFNNDGAEAVL 123 DK AEVPDALL LGFGF E+G+VTP PQ GNP+PR+FRL DEAVINR+GFNN+G A Sbjct: 64 DKDAEVPDALLGLGFGFAEVGTVTPLPQAGNPKPRIFRLTADEAVINRLGFNNEGHAAAE 123 Query: 124 RRLAARASAGGIVGVNVGANKDSPDRAADYVKLIETFAPVASYFTVNVSSPNTPGLRNLQ 183 +RLAAR GIVGVN+GANKDS DR DY + + FA ASY TVN+SSPNTPGLRN+Q Sbjct: 124 KRLAARKGRPGIVGVNIGANKDSADRIGDYERGVGRFARHASYLTVNISSPNTPGLRNMQ 183 Query: 184 QSAALDDLLARVIDTRERVRKNAGDSPVLLKIAPDLSLAELDDVVHIARSRRVDGMIVAN 243 L +LL+RV+ R A P+ LKIAPDL AEL+D+ +R+DG+IV+N Sbjct: 184 AREQLGELLSRVMAARASA---ATQPPIFLKIAPDLVEAELEDIAAEVVEKRIDGIIVSN 240 Query: 244 TTLARPSTLREENRAKEQGGLSGRPLFRLSTRMVAETYVRVEGAFPLIGVGGIDSGGAAL 303 TT++RP LR + +E GGLSG+PLF ST ++A+ + +IGVGG+DS AL Sbjct: 241 TTISRPP-LRSGDVGRETGGLSGKPLFERSTIVLAKMRKLLGPGIAIIGVGGVDSAETAL 299 Query: 304 TKIRAGASLIQLYSSLVYKG 323 KIRAGA L+QLY+ ++Y G Sbjct: 300 EKIRAGADLVQLYTGMIYAG 319