BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0162.0001.p (377 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1712 [GEPR] COG0477 Permeases of the major facilitator superf... 403 e-112 yebQ [GEPR] COG0477 Permeases of the major facilitator superfami... 395 e-110 Z2875 [GEPR] COG0477 Permeases of the major facilitator superfam... 395 e-110 ECs2538 [GEPR] COG0477 Permeases of the major facilitator superf... 395 e-110 STM1843 [GEPR] COG0477 Permeases of the major facilitator superf... 390 e-108 >YPO1712 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 403 bits (1036), Expect = e-112, Method: Compositional matrix adjust. Identities = 215/362 (59%), Positives = 267/362 (73%), Gaps = 2/362 (0%) Query: 10 DGLPQPQRNWAILTIALGLVMAVVDGSIANVALPTIARDLNASPAFSIWIVNGYQLAITI 69 DGLP PQR AIL IALG++MAV+DG+IANVALPTIARDLN SPA SIW+VN YQLAITI Sbjct: 7 DGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAYQLAITI 66 Query: 70 SLLPLASLGEIIGYRRVYLAGLLLFTLASLFCALSHTLPLLTVARILQGFGAAGILSVNT 129 SLL +ASLG+IIGYRRVY AGLL+F++ SLFCALS +L LT AR+LQGFGAA ++SVNT Sbjct: 67 SLLSMASLGDIIGYRRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAALMSVNT 126 Query: 130 ALVRFIYPHSQLGRGIGVNALVVAISAAVGPTIASFILAVGTWPYLFAINVPLGIVTLAL 189 AL+R IYP +QLGRGIG+N L+VA+S+A GP+IA+ +L+V +W +LFA+NVP+G++ L Sbjct: 127 ALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIAAAVLSVASWQWLFALNVPIGLLAWCL 186 Query: 190 GWRFLP--HTRPAVHAFDWQSAAMSAIAFGFGISAIDSAGHGGSLYLCALEFAVAAVASH 247 G +FLP +T+ + FD S ++A+ FG I+AI G S + A + + Sbjct: 187 GIKFLPANNTKSNGNRFDITSCVLNALTFGLLITAISGFSQGQSPAVIAAQVVALLLIGF 246 Query: 248 LLYRRQQHLPSPLLPVDLLRIPIFALSIGTSIASFCGQMLAFVAMPFYLENHFGYSAVQI 307 RRQ PLLPVDLLRIPIFALSIGTSI SF QMLA V++PF+L+ G V Sbjct: 247 FFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQTVLGRDEVAT 306 Query: 308 GLLITPWPIAVAFAAPLAGWLVERYPAGLLGGIGLLLFATGLGTLALMPXAPRWWHSCWR 367 GLL+TPWP+A AP+AG LVERY AGLLGGIGL +FA+GL LA++P P WR Sbjct: 307 GLLLTPWPLATMVIAPIAGRLVERYHAGLLGGIGLAVFASGLFLLAVLPANPSDVDIIWR 366 Query: 368 AI 369 I Sbjct: 367 MI 368 >yebQ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 494 Score = 395 bits (1015), Expect = e-110, Method: Compositional matrix adjust. Identities = 205/364 (56%), Positives = 263/364 (72%), Gaps = 2/364 (0%) Query: 8 HPDGLPQPQRNWAILTIALGLVMAVVDGSIANVALPTIARDLNASPAFSIWIVNGYQLAI 67 DGLP PQR AILTI +G+ MAV+DG+IANVALPTIA DL+A+PA SIW+VN YQ+AI Sbjct: 42 QADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAI 101 Query: 68 TISLLPLASLGEIIGYRRVYLAGLLLFTLASLFCALSHTLPLLTVARILQGFGAAGILSV 127 ISLL + LG++ GYRR+Y GL++F L+SLFCALS +L +LT+AR++QGFG A ++SV Sbjct: 102 VISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAALMSV 161 Query: 128 NTALVRFIYPHSQLGRGIGVNALVVAISAAVGPTIASFILAVGTWPYLFAINVPLGIVTL 187 NTAL+R IYP LGRG+G+N+ +VA+S+A GPTIA+ IL++ +W +LF INVPLGI+ L Sbjct: 162 NTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIAL 221 Query: 188 ALGWRFLP--HTRPAVHAFDWQSAAMSAIAFGFGISAIDSAGHGGSLYLCALEFAVAAVA 245 L RFLP +R + FD SA M+A+ FG I+A+ G SL L A E V V Sbjct: 222 LLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVVV 281 Query: 246 SHLLYRRQQHLPSPLLPVDLLRIPIFALSIGTSIASFCGQMLAFVAMPFYLENHFGYSAV 305 RRQ LP PLLPVDLLRIP+F+LSI TS+ SFC QMLA V++PFYL+ G S V Sbjct: 282 GIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSEV 341 Query: 306 QIGLLITPWPIAVAFAAPLAGWLVERYPAGLLGGIGLLLFATGLGTLALMPXAPRWWHSC 365 + GLL+TPWP+A APLAG+L+ER AGLLG +GL + A GL +L L+P +P + Sbjct: 342 ETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINII 401 Query: 366 WRAI 369 W I Sbjct: 402 WPMI 405 >Z2875 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 494 Score = 395 bits (1015), Expect = e-110, Method: Compositional matrix adjust. Identities = 205/364 (56%), Positives = 263/364 (72%), Gaps = 2/364 (0%) Query: 8 HPDGLPQPQRNWAILTIALGLVMAVVDGSIANVALPTIARDLNASPAFSIWIVNGYQLAI 67 DGLP PQR AILTI +G+ MAV+DG+IANVALPTIA DL+A+PA SIW+VN YQ+AI Sbjct: 42 QADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAI 101 Query: 68 TISLLPLASLGEIIGYRRVYLAGLLLFTLASLFCALSHTLPLLTVARILQGFGAAGILSV 127 ISLL + LG++ GYRR+Y GL++F L+SLFCALS +L +LT+AR++QGFG A ++SV Sbjct: 102 VISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMSV 161 Query: 128 NTALVRFIYPHSQLGRGIGVNALVVAISAAVGPTIASFILAVGTWPYLFAINVPLGIVTL 187 NTAL+R IYP LGRG+G+N+ +VA+S+A GPTIA+ IL++ +W +LF INVPLGI+ L Sbjct: 162 NTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIAL 221 Query: 188 ALGWRFLP--HTRPAVHAFDWQSAAMSAIAFGFGISAIDSAGHGGSLYLCALEFAVAAVA 245 L RFLP +R + FD SA M+A+ FG I+A+ G SL L A E V V Sbjct: 222 LLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVVV 281 Query: 246 SHLLYRRQQHLPSPLLPVDLLRIPIFALSIGTSIASFCGQMLAFVAMPFYLENHFGYSAV 305 RRQ LP PLLPVDLLRIP+F+LSI TS+ SFC QMLA V++PFYL+ G S V Sbjct: 282 GIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSEV 341 Query: 306 QIGLLITPWPIAVAFAAPLAGWLVERYPAGLLGGIGLLLFATGLGTLALMPXAPRWWHSC 365 + GLL+TPWP+A APLAG+L+ER AGLLG +GL + A GL +L L+P +P + Sbjct: 342 ETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINII 401 Query: 366 WRAI 369 W I Sbjct: 402 WPMI 405 >ECs2538 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 494 Score = 395 bits (1015), Expect = e-110, Method: Compositional matrix adjust. Identities = 205/364 (56%), Positives = 263/364 (72%), Gaps = 2/364 (0%) Query: 8 HPDGLPQPQRNWAILTIALGLVMAVVDGSIANVALPTIARDLNASPAFSIWIVNGYQLAI 67 DGLP PQR AILTI +G+ MAV+DG+IANVALPTIA DL+A+PA SIW+VN YQ+AI Sbjct: 42 QADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAI 101 Query: 68 TISLLPLASLGEIIGYRRVYLAGLLLFTLASLFCALSHTLPLLTVARILQGFGAAGILSV 127 ISLL + LG++ GYRR+Y GL++F L+SLFCALS +L +LT+AR++QGFG A ++SV Sbjct: 102 VISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMSV 161 Query: 128 NTALVRFIYPHSQLGRGIGVNALVVAISAAVGPTIASFILAVGTWPYLFAINVPLGIVTL 187 NTAL+R IYP LGRG+G+N+ +VA+S+A GPTIA+ IL++ +W +LF INVPLGI+ L Sbjct: 162 NTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIAL 221 Query: 188 ALGWRFLP--HTRPAVHAFDWQSAAMSAIAFGFGISAIDSAGHGGSLYLCALEFAVAAVA 245 L RFLP +R + FD SA M+A+ FG I+A+ G SL L A E V V Sbjct: 222 LLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVVV 281 Query: 246 SHLLYRRQQHLPSPLLPVDLLRIPIFALSIGTSIASFCGQMLAFVAMPFYLENHFGYSAV 305 RRQ LP PLLPVDLLRIP+F+LSI TS+ SFC QMLA V++PFYL+ G S V Sbjct: 282 GIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSEV 341 Query: 306 QIGLLITPWPIAVAFAAPLAGWLVERYPAGLLGGIGLLLFATGLGTLALMPXAPRWWHSC 365 + GLL+TPWP+A APLAG+L+ER AGLLG +GL + A GL +L L+P +P + Sbjct: 342 ETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINII 401 Query: 366 WRAI 369 W I Sbjct: 402 WPMI 405 >STM1843 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 457 Score = 390 bits (1001), Expect = e-108, Method: Compositional matrix adjust. Identities = 205/362 (56%), Positives = 261/362 (72%), Gaps = 8/362 (2%) Query: 10 DGLPQPQRNWAILTIALGLVMAVVDGSIANVALPTIARDLNASPAFSIWIVNGYQLAITI 69 DGLP PQR AILTI +G+ MAV+DG+IANVALPTIA DL+ASPA SIWIVN YQ+AI + Sbjct: 7 DGLPLPQRYGAILTIIIGISMAVLDGAIANVALPTIATDLHASPASSIWIVNAYQIAIVV 66 Query: 70 SLLPLASLGEIIGYRRVYLAGLLLFTLASLFCALSHTLPLLTVARILQGFGAAGILSVNT 129 SLL L+ LG++ GY R+Y GL++F L+SLFCALS +L +LT+ARI QGFG A ++SVNT Sbjct: 67 SLLSLSFLGDMFGYHRIYKCGLVVFLLSSLFCALSDSLQMLTLARIAQGFGGAALMSVNT 126 Query: 130 ALVRFIYPHSQLGRGIGVNALVVAISAAVGPTIASFILAVGTWPYLFAINVPLGIVTLAL 189 AL+R IYP LGRG+G+N+ +VA+S+A GPTIA+ IL++ +W +LF INVPLGI+ L L Sbjct: 127 ALIRLIYPQRHLGRGMGINSFIVAVSSAAGPTIAAAILSISSWKWLFLINVPLGIIALIL 186 Query: 190 GWRFLP-----HTRPAVHAFDWQSAAMSAIAFGFGISAIDSAGHGGSLYLCALEFAVAAV 244 RFLP T+P FD SA M+A+ FG I+A+ G SL L E V V Sbjct: 187 AIRFLPANIAHDTKP---RFDLPSAVMNALTFGLLITALSGFAQGQSLTLIGAELLVLVV 243 Query: 245 ASHLLYRRQQHLPSPLLPVDLLRIPIFALSIGTSIASFCGQMLAFVAMPFYLENHFGYSA 304 RRQ LP PLLP+DLLRIP+F+LSIGTSI SFC QMLA V++PFYL+ G S Sbjct: 244 VGFFFVRRQLSLPVPLLPIDLLRIPLFSLSIGTSICSFCAQMLAMVSLPFYLQTVLGRSE 303 Query: 305 VQIGLLITPWPIAVAFAAPLAGWLVERYPAGLLGGIGLLLFATGLGTLALMPXAPRWWHS 364 V+ GLL+TPWP+A APLAG+L+ER AGLLG +G+++ A GL L ++P +P + Sbjct: 304 VETGLLLTPWPLATMVMAPLAGYLIERLHAGLLGALGMVIMAAGLFALVMLPASPSDLNI 363 Query: 365 CW 366 W Sbjct: 364 IW 365