BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0156.0081.p (326 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll2877_1 [E] COG1305 Transglutaminase-like enzymes, putative cy... 399 e-111 AGl1961_1 [E] COG1305 Transglutaminase-like enzymes, putative cy... 381 e-105 Rv2566_1 [E] COG1305 Transglutaminase-like enzymes, putative cys... 318 1e-86 MT2642_1 [E] COG1305 Transglutaminase-like enzymes, putative cys... 315 7e-86 ML2678_1 [E] COG1305 Transglutaminase-like enzymes, putative cys... 143 7e-34 >mll2877_1 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Mlo Mesorhizobium loti Length = 273 Score = 399 bits (1024), Expect = e-111, Method: Compositional matrix adjust. Identities = 181/273 (66%), Positives = 228/273 (83%) Query: 1 VSISVALHHVTHYTYDRPIDLGPQTIRLRPAPHTRTPITSYSLKVTPANHFVNWQQDPQG 60 ++I A++H+THY YDRP+ LGPQ IRL+PAPH+RT + S+SLKV PANHFVN QQDP G Sbjct: 1 MAILAAVYHLTHYKYDRPVVLGPQIIRLQPAPHSRTKVLSHSLKVEPANHFVNLQQDPYG 60 Query: 61 NWLARYVFPEKTTELKVEVDFTADMTVVNPFDFFVEPYANSFPFEYPGDLKTELAPYFET 120 N+LAR+VFPE TELK+EVD ADMTV NPFDFFVEP A +FPFEYP +++ +LA Y Sbjct: 61 NFLARFVFPEPVTELKIEVDLVADMTVYNPFDFFVEPSAETFPFEYPEEIRDDLAIYRTP 120 Query: 121 DEPGPLLAAYLKQIPCQADSTVNFLVELNAQLQKKIGYVIRMEAGIQTPEETLAAGSGSC 180 + GPLL+A+L+ I A +TVNFLV+LNA+LQ++I Y++RME G+ +PEETL+AG GSC Sbjct: 121 EPTGPLLSAFLRTIDTSAKNTVNFLVDLNARLQREIAYIVRMETGVFSPEETLSAGKGSC 180 Query: 181 RDSAWLLIQTLRHLGLAARFVSGYLIQLRPDIDPLEGPREVEIDFTDLHAWAEVYLPGAG 240 RDS+WLL+Q LR+LG+AARFVSGYLIQL+PD+ L+GP +DFTDLHAW EVYLPGAG Sbjct: 181 RDSSWLLVQILRNLGIAARFVSGYLIQLKPDLVALDGPAGTSVDFTDLHAWCEVYLPGAG 240 Query: 241 WIGFDVTSGMLTGEGHIPVCATPHYRSAAPVTG 273 WIGFD TSG+LTGE H+P+ ATPH+R+AAP++G Sbjct: 241 WIGFDPTSGLLTGESHVPLAATPHFRNAAPISG 273 >AGl1961_1 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 306 Score = 381 bits (978), Expect = e-105, Method: Compositional matrix adjust. Identities = 175/274 (63%), Positives = 222/274 (81%), Gaps = 1/274 (0%) Query: 1 VSISVALHHVTHYTYDRPIDLGPQTIRLRPAPHTRTPITSYSLKVTPANHFVNWQQDPQG 60 ++I +++H+THY YD P+ LGPQ IRL+PA H+RT + S+SLKV+P+NHFVN QQDP G Sbjct: 33 MAIKASIYHLTHYKYDNPVRLGPQIIRLKPASHSRTHVISHSLKVSPSNHFVNLQQDPYG 92 Query: 61 NWLARYVFPEKTTELKVEVDFTADMTVVNPFDFFVEPYANSFPFEYPGDLKTELAPYFET 120 N+LAR+VFPE TE K+EVD ADMTV NPFDFFVE A +PF+YP +L+ +L+ Y + Sbjct: 93 NYLARFVFPEPATEFKIEVDLVADMTVYNPFDFFVEEEATKWPFDYPQELRDDLSIYTKP 152 Query: 121 DEPGPLLAAYLKQIPCQADS-TVNFLVELNAQLQKKIGYVIRMEAGIQTPEETLAAGSGS 179 + GPLLAA++ + + TV+ +V LNA+LQ++IGYVIRME G+QTPEETLA+G GS Sbjct: 153 EPTGPLLAAFMATVDRTPEQPTVDMVVGLNARLQQEIGYVIRMEPGVQTPEETLASGKGS 212 Query: 180 CRDSAWLLIQTLRHLGLAARFVSGYLIQLRPDIDPLEGPREVEIDFTDLHAWAEVYLPGA 239 CRD++WLL+Q LRHLGLAARFVSGYLIQL PD+ L+GP E+DFTDLHAWAE Y+PGA Sbjct: 213 CRDTSWLLVQVLRHLGLAARFVSGYLIQLTPDLKALDGPSGTEVDFTDLHAWAEFYMPGA 272 Query: 240 GWIGFDVTSGMLTGEGHIPVCATPHYRSAAPVTG 273 GWIG D TSG+LTGE HIP+ ATPHYR+AAP++G Sbjct: 273 GWIGLDPTSGLLTGESHIPLAATPHYRNAAPISG 306 >Rv2566_1 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Mtu Mycobacterium tuberculosis H37Rv Length = 326 Score = 318 bits (815), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 157/299 (52%), Positives = 199/299 (66%), Gaps = 11/299 (3%) Query: 1 VSISVALHHVTHYTYDRPIDLGPQTIRLRPAPHTRTPITSYSLKVTPANHFVNWQQDPQG 60 +SI VAL H T YT+DR + + P +RLRPAPH+RT I +YSL++ PA+HF+NWQQD G Sbjct: 28 MSIKVALEHRTSYTFDRLVRVYPHIVRLRPAPHSRTSIEAYSLRIEPADHFINWQQDALG 87 Query: 61 NWLARYVFPEKTTELKVEVDFTADMTVVNPFDFFVEPYANSFP---FEYPGDLKTELAPY 117 N+LAR VFP +L++ V AD+ V+NPFDFF+E +A +P YP L +L PY Sbjct: 88 NFLARLVFPNPMRQLRITVGLIADLKVINPFDFFIEDWAEIWPCAGMAYPKALADDLRPY 147 Query: 118 FE-TDE------PGPLLAAYLKQIPC-QADSTVNFLVELNAQLQKKIGYVIRMEAGIQTP 169 DE PG L A+++ T++FLV LN + +GY +RME G+QTP Sbjct: 148 LRPVDEDGDGSGPGELTQAWVRNFTVPDGTRTIDFLVALNRAINADVGYCVRMEPGVQTP 207 Query: 170 EETLAAGSGSCRDSAWLLIQTLRHLGLAARFVSGYLIQLRPDIDPLEGPREVEIDFTDLH 229 + TL G GSCRDSAWLL+ LR GLAARFVSGYL+QL DI+ L+GP DFTDLH Sbjct: 208 DFTLRTGVGSCRDSAWLLVSILRQFGLAARFVSGYLVQLASDIEALDGPSGPAADFTDLH 267 Query: 230 AWAEVYLPGAGWIGFDVTSGMLTGEGHIPVCATPHYRSAAPVTGTAGVANVEFGFEMSV 288 AWAE Y+PGAGWIG D TSG+L GEGHIP+ ATPH SAAP++G V + F +V Sbjct: 268 AWAEAYIPGAGWIGLDPTSGLLAGEGHIPLAATPHPASAAPISGGTDVCDTVLEFSNTV 326 >MT2642_1 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases MtC Mycobacterium tuberculosis CDC1551 Length = 337 Score = 315 bits (808), Expect = 7e-86, Method: Compositional matrix adjust. Identities = 155/290 (53%), Positives = 196/290 (67%), Gaps = 11/290 (3%) Query: 1 VSISVALHHVTHYTYDRPIDLGPQTIRLRPAPHTRTPITSYSLKVTPANHFVNWQQDPQG 60 +SI VAL H T YT+DR + + P +RLRPAPH+RT I +YSL++ PA+HF+NWQQD G Sbjct: 44 MSIKVALEHRTSYTFDRLVRVYPHIVRLRPAPHSRTSIEAYSLRIEPADHFINWQQDALG 103 Query: 61 NWLARYVFPEKTTELKVEVDFTADMTVVNPFDFFVEPYANSFP---FEYPGDLKTELAPY 117 N+LAR VFP +L++ V AD+ V+NPFDFF+E +A +P YP L +L PY Sbjct: 104 NFLARLVFPNPMRQLRITVGLIADLKVINPFDFFIEDWAEIWPCAGMAYPKALADDLRPY 163 Query: 118 FE-TDE------PGPLLAAYLKQIPC-QADSTVNFLVELNAQLQKKIGYVIRMEAGIQTP 169 DE PG L A+++ T++FLV LN + +GY +RME G+QTP Sbjct: 164 LRPVDEDGDGSGPGELTQAWVRNFTVPDGTRTIDFLVALNRAINADVGYCVRMEPGVQTP 223 Query: 170 EETLAAGSGSCRDSAWLLIQTLRHLGLAARFVSGYLIQLRPDIDPLEGPREVEIDFTDLH 229 + TL G GSCRDSAWLL+ LR GLAARFVSGYL+QL DI+ L+GP DFTDLH Sbjct: 224 DFTLRTGVGSCRDSAWLLVSILRQFGLAARFVSGYLVQLASDIEALDGPSGPAADFTDLH 283 Query: 230 AWAEVYLPGAGWIGFDVTSGMLTGEGHIPVCATPHYRSAAPVTGTAGVAN 279 AWAE Y+PGAGWIG D TSG+L GEGHIP+ ATPH SAAP++G V + Sbjct: 284 AWAEAYIPGAGWIGLDPTSGLLAGEGHIPLAATPHPASAAPISGGTDVCD 333 >ML2678_1 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Mle Mycobacterium leprae Length = 315 Score = 143 bits (360), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 77/222 (34%), Positives = 119/222 (53%), Gaps = 19/222 (8%) Query: 1 VSISVALHHVTHYTYDRPIDLGPQTIRLRPAPHTRTPITSYSLKVTPANHFVNWQQDPQG 60 ++I V L H T YT++R + + P +R+ APH+R PI ++SL++ PA HF+N QQD G Sbjct: 7 MNIKVTLEHRTSYTFNRLVQVCPHVVRVHLAPHSRPPIEAHSLQIEPAGHFINCQQDTLG 66 Query: 61 NWLARYVFPEKTTELKVEVDFTADMTVVNPFDFFVEPYANSFP--------FEYPGDLKT 112 N L R V P + ++ +++PFD ++E +A ++P F YP L Sbjct: 67 NGLTRLVLPNPMRRRSIGFGLITNLKMISPFDCYIENWAETWPATARSGPTFTYPEALAE 126 Query: 113 ELAPYFE-TDEPG------PLLAAYLKQIPC----QADSTVNFLVELNAQLQKKIGYVIR 161 +L PY DE G L+ A+++ P + + +NFLV N + ++ ++ Sbjct: 127 DLKPYLRPVDEAGNRFVDNELVWAWIRNFPVPDGIRTINFINFLVAFNQAMNAEVSDIVC 186 Query: 162 MEAGIQTPEETLAAGSGSCRDSAWLLIQTLRHLGLAARFVSG 203 ME G+ T + TL G SCRDSAWLL+ L + L A VS Sbjct: 187 MEHGVPTTDFTLRTGISSCRDSAWLLVSILWQMRLTAWVVSS 228