BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0156.0037.p (539 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA0615 [GEPR] COG0477 Permeases of the major facilitator superfa... 660 0.0 PA2701 [GEPR] COG0477 Permeases of the major facilitator superfa... 407 e-113 AGl1740 [GEPR] COG0477 Permeases of the major facilitator superf... 394 e-109 SMa0383 [GEPR] COG0477 Permeases of the major facilitator superf... 380 e-105 SMa1814 [GEPR] COG0477 Permeases of the major facilitator superf... 363 e-100 >MA0615 [GEPR] COG0477 Permeases of the major facilitator superfamily Mac Methanosarcina acetivorans str.C2A Length = 539 Score = 660 bits (1702), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/517 (65%), Positives = 404/517 (78%) Query: 5 SPWIAFRHTTFTVIWIATVVANVGTWMYNAASGWLMTSLDANPLTVSLVQVASSLPMFLF 64 S W FR+T++TV+W ATV++N+GTWMYNA SGW+MTSL+A+PL VSLVQVA+SLPMFLF Sbjct: 5 SSWAPFRYTSYTVLWTATVISNIGTWMYNAGSGWMMTSLNADPLIVSLVQVATSLPMFLF 64 Query: 65 ALPAGALADTVDKRRFLIGCEIVLTIIAAASAALVGLNLVTPPILLLFTFLLGAGAAFTA 124 A+PAGAL+D VD+R FL+ V T+IA A LV NLVTP ILLLFTFLLG GAA TA Sbjct: 65 AMPAGALSDIVDRRLFLVIVTSVTTVIATIIAMLVAFNLVTPSILLLFTFLLGTGAALTA 124 Query: 125 PAWQSVVPQLVPRQDLAAAVASNGVGVNISRAIGPALGGAVIGGLGIAAPFWINALSNFA 184 P W+S+VPQLVPR LA AVA++ +G+NISRA+GPA+GG +I G+GIA+PFW+NA+SN Sbjct: 125 PTWRSIVPQLVPRDVLAPAVAADSMGINISRAVGPAVGGLIIAGIGIASPFWLNAISNLG 184 Query: 185 VIGALLWWRLASSQGNALPPERLAGAMVVGFRHARFNPKLRATLVRAATFFFFASAYWAL 244 +I ALLWWR + LP ER AM+ G RHAR+N LRATL+R F FASAYWAL Sbjct: 185 IIVALLWWRPGKAVAQRLPAERFVSAMITGVRHARYNSHLRATLMRTVGFILFASAYWAL 244 Query: 245 LPLVARNQIAGGPALYGILLGAIGVGAVIGAFMLPWMKSTFGPNGLVAAGTVGTALSLIL 304 LPLVAR+QIAGGP LYG LLG IG AVIGAF+LPW+K GP+ LVAAGTVGTA++L+L Sbjct: 245 LPLVARSQIAGGPELYGFLLGVIGASAVIGAFILPWLKERLGPDRLVAAGTVGTAVTLVL 304 Query: 305 LGIARYPEIGLAACLIAGVSWIAVLATINVSVQVSLPDWVRGRGLAIFVTAFFGAMTAGS 364 G+AR P +GL A +IAG+SWI VLA +++S QVSLPDWVRGRGLA FVT FGAMT GS Sbjct: 305 FGLAREPSVGLLASIIAGMSWITVLANLSISAQVSLPDWVRGRGLATFVTVLFGAMTLGS 364 Query: 365 VLWGQLASGLGLPAAHFLAAAGALAGIALTWRWKLQTGAGVDLAPSMHWPAPILAIDADA 424 WGQ+A +GLP AHFLAAAG L I TWRWKLQTGAGVDL PSMHWP P+L + Sbjct: 365 AAWGQIAGLVGLPDAHFLAAAGVLISIPFTWRWKLQTGAGVDLTPSMHWPTPVLTHKVEY 424 Query: 425 DRGPVLITVEYFIAPEKRDAFLAAVTELGRQRRSDGAYSWDVFEDAAESGRFLETFMVAS 484 D+GPVL+T+EY + P R+AFL A+ L +RR DGAY+W VFED A+ GRFLETFMV S Sbjct: 425 DQGPVLVTIEYRVEPGNREAFLDALKRLSNERRRDGAYAWYVFEDVADQGRFLETFMVES 484 Query: 485 WLEHLRQHQRVTNTDKVVQDAIREYGAAAEPKVTHFI 521 WLEHLRQH RVTN D+++QD + Y A P+VTHF+ Sbjct: 485 WLEHLRQHGRVTNADRIIQDTVNRYHARGAPQVTHFV 521 >PA2701 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 529 Score = 407 bits (1046), Expect = e-113, Method: Compositional matrix adjust. Identities = 235/524 (44%), Positives = 340/524 (64%), Gaps = 2/524 (0%) Query: 4 ASPWIAFRHTTFTVIWIATVVANVGTWMYNAASGWLMTSLDANPLTVSLVQVASSLPMFL 63 ASPW R TTF +W+A++ +N+GTWM+ +GWLMTSL A+PL V+LVQVA SLPMF Sbjct: 6 ASPWSPLRQTTFRWLWLASIASNIGTWMHEVGAGWLMTSLSASPLNVALVQVAGSLPMFF 65 Query: 64 FALPAGALADTVDKRRFLIGCEIVLTIIAAASAALVGLNLVTPPILLLFTFLLGAGAAFT 123 ALPAGALAD VDKRR+L+G ++ + ++A A+L L L + +LL T +G G A Sbjct: 66 LALPAGALADIVDKRRYLLGVQLWMALVATLLASLTLLQLTSVWLLLGLTLCMGIGTALM 125 Query: 124 APAWQSVVPQLVPRQDLAAAVASNGVGVNISRAIGPALGGAVIGGLGIAAPFWINALSNF 183 PAW + P+LV + +L AAVA + VGVN++RA+GPA+ G ++ +G F +NALS F Sbjct: 126 MPAWSATTPELVGKDELPAAVALSSVGVNLARAVGPAIAGVLVSLVGPWLTFALNALSFF 185 Query: 184 AVIGALLWWRLASSQGNALPPERLAGAMVVGFRHARFNPKLRATLVRAATFFFFASAYWA 243 AVI LL W+ + + LP ERL GA+ G+R++R + L++ LVRA FF ASA + Sbjct: 186 AVIAVLLAWK-REAVPSVLPAERLFGALRAGWRYSRSSRPLQSVLVRAVAFFLGASAGMS 244 Query: 244 LLPLVARNQIAGGPALYGILLGAIGVGAVIGAFMLPWMKSTFGPNGLVAAGTVGTALSLI 303 LLPL+ R ++ G +G+LLG++GVGAV+GA LP ++ G + LV +V AL L+ Sbjct: 245 LLPLIVRGELHGNAMDFGLLLGSVGVGAVLGAAFLPRLRERLGSDRLVLLSSVLYALVLV 304 Query: 304 LLGIARYPEIGLAACLIAGVSWIAVLATINVSVQVSLPDWVRGRGLAIFVTAFFGAMTAG 363 L + R + + L++G +WIAVL+++ V+ Q S+P WVR R LA+++ FFG+M AG Sbjct: 305 ALALLRNLYLLVPVMLLSGAAWIAVLSSLQVAAQTSVPAWVRARALAVYILVFFGSMAAG 364 Query: 364 SVLWGQLASGLGLPAAHFLAAAGALAGIALTWRWKLQTGAGVDLAPSMHWPAPILAIDAD 423 LWG +AS L + A A+A L G+ + R +L DLAPS+HWPAP++ + D Sbjct: 365 GALWGLVASHLSITFALLCASAALLLGLFASLRCRLPVTEAEDLAPSLHWPAPLVDEEVD 424 Query: 424 ADRGPVLITVEYFIAPEKRDAFLAAVTELGRQRRSDGAYSWDVFEDAAESGRFLETFMVA 483 +RGPV++T+EY I P+ AF AA+ E+ RR +GA SW + +D+ +LE F+ Sbjct: 425 QERGPVMVTLEYDIDPQDAAAFQAAMVEVRAMRRRNGAVSWGLVQDSGNRRLWLEFFIDE 484 Query: 484 SWLEHLRQHQRVTNTDKVVQDAIREYGAAA-EPKVTHFIAASFR 526 SWLEHLR HQRVT + V+ A R + +A E ++ H++ + R Sbjct: 485 SWLEHLRHHQRVTRGELRVEAAARRFQSAGVEVRIRHYLHGAAR 528 >AGl1740 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 532 Score = 394 bits (1012), Expect = e-109, Method: Compositional matrix adjust. Identities = 230/509 (45%), Positives = 317/509 (62%), Gaps = 3/509 (0%) Query: 14 TFTVIWIATVVANVGTWMYNAASGWLMTSLDANPLTVSLVQVASSLPMFLFALPAGALAD 73 F V+W ATV+ N G++M + AS WLMT L A+P V+LVQ A +LP+FL A+PAG L D Sbjct: 18 VFAVLWAATVLGNTGSFMRDVASSWLMTDLSASPAAVALVQAAGTLPIFLLAIPAGVLTD 77 Query: 74 TVDKRRFLIGCEIVLTIIAAASAALVGLNLVTPPILLLFTFLLGAGAAFTAPAWQSVVPQ 133 +D+R+FLI +++L ++ L +++ L+ TFL G GAA P WQ++VP+ Sbjct: 78 ILDRRKFLIAVQLLLASVSVTLMVLAHTGMLSVSALIGLTFLGGIGAALMGPTWQAIVPE 137 Query: 134 LVPRQDLAAAVASNGVGVNISRAIGPALGGAVIGGLGIAAPFWINALSNFAVIGALLWWR 193 LV R+D+ +AVA N +G+NI+R+IGPA+GG ++ G A + + S F VI ALLWW Sbjct: 138 LVKREDIKSAVALNSLGINIARSIGPAVGGILLAAFGAAFTYGADVASYFFVIAALLWWP 197 Query: 194 LASSQGNALPPERLAGAMVVGFRHARFNPKLRATLVRAATFFFFASAYWALLPLVARNQI 253 A + NAL E GA G R+ R + L L+RAA FF FASA WALLPLVAR + Sbjct: 198 RAKNANNAL-QENFFGAFRAGLRYTRASRPLHVVLLRAAIFFAFASAVWALLPLVARQLL 256 Query: 254 AGGPALYGILLGAIGVGAVIGAFMLPWMKSTFGPNGLVAAGTVGTALSLILLGIARYPEI 313 G + YGILLGA+G GA+ GA ++P +++ F +GL+ + TAL + L A + Sbjct: 257 GGDASFYGILLGAVGAGAIAGALVMPKLRARFDADGLLLGAAIVTALVMAGLSFAPPKWL 316 Query: 314 GLAACLIAGVSWIAVLATINVSVQVSLPDWVRGRGLAIFVTAFFGAMTAGSVLWGQLASG 373 + L G +WI L T+N + Q LP+WVRGRGLA+++T F GAMTAGS+ WG + Sbjct: 317 AIIILLFLGGAWITALTTLNGAAQAILPNWVRGRGLAVYLTVFNGAMTAGSIGWGAVGEA 376 Query: 374 LGLPAAHFLAAAGALAGIALTWRWKLQTGAGVDLAPSMHWPAPILAIDADADRGPVLITV 433 G+P + AAG + R KL G D+ PS HWP P++A DRGPVLI + Sbjct: 377 AGVPGTLLIGAAGLFIAGLIMHRLKLPAG-DADMVPSNHWPEPLVAEPVAHDRGPVLILI 435 Query: 434 EYFIAPEKRDAFLAAVTELGRQRRSDGAYSWDVFEDAAESGRFLETFMVASWLEHLRQHQ 493 EY + + R AFL A+ EL ++RR DGAY W V ED+A+ + +E FMV SW EHLRQH+ Sbjct: 436 EYTVEKDHRSAFLHALDELSQERRRDGAYGWGVTEDSADPQKIVEWFMVESWAEHLRQHK 495 Query: 494 RVTNTDKVVQDAIREYGAAAE-PKVTHFI 521 RV+N D +Q + Y + E P V HF+ Sbjct: 496 RVSNADADLQGKVLAYHSGLEKPVVRHFL 524 >SMa0383 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 532 Score = 380 bits (977), Expect = e-105, Method: Compositional matrix adjust. Identities = 222/508 (43%), Positives = 312/508 (61%), Gaps = 3/508 (0%) Query: 15 FTVIWIATVVANVGTWMYNAASGWLMTSLDANPLTVSLVQVASSLPMFLFALPAGALADT 74 F V+W ATV+ N G++M + AS WLMT L A+P V++VQ A +LP+FL A+PAG L D Sbjct: 19 FAVLWTATVLGNTGSFMRDVASAWLMTDLSASPAAVAMVQAAGTLPIFLLAIPAGVLTDI 78 Query: 75 VDKRRFLIGCEIVLTIIAAASAALVGLNLVTPPILLLFTFLLGAGAAFTAPAWQSVVPQL 134 +D+R+FLI +++L ++ + L +++ L+ TFL G GAA P WQ++VP+L Sbjct: 79 LDRRKFLIAVQLLLASVSISLMVLSQTGMLSVSSLIGLTFLGGIGAALMGPTWQAIVPEL 138 Query: 135 VPRQDLAAAVASNGVGVNISRAIGPALGGAVIGGLGIAAPFWINALSNFAVIGALLWWRL 194 V R+D+ +AVA N +G+NI+R+IGPA GG ++ G + + S VI AL+WW Sbjct: 139 VKREDVKSAVALNSLGINIARSIGPAAGGLLLAAFGAGITYGADVASYIVVIAALVWWPR 198 Query: 195 ASSQGNALPPERLAGAMVVGFRHARFNPKLRATLVRAATFFFFASAYWALLPLVARNQIA 254 A + +AL E GA G R+ R + L L+RAA FF FASA WALLPLVAR + Sbjct: 199 AKNANDAL-QENFFGAFRAGLRYTRSSTPLHVVLLRAAIFFAFASAVWALLPLVARQLLG 257 Query: 255 GGPALYGILLGAIGVGAVIGAFMLPWMKSTFGPNGLVAAGTVGTALSLILLGIARYPEIG 314 G YGILLGA+G GA+ GA ++P ++ +GL+ + TA + +L +A + Sbjct: 258 GDAGFYGILLGAVGAGAIGGALVMPKLRERLSSDGLLLGAALITAAVMGVLALAPPKVVA 317 Query: 315 LAACLIAGVSWIAVLATINVSVQVSLPDWVRGRGLAIFVTAFFGAMTAGSVLWGQLASGL 374 + L G +WI L T+N + Q LP+WVRGRGLA+++T F GAMTAGS+ WG + + Sbjct: 318 IIVLLFLGGAWITALTTLNGTAQSVLPNWVRGRGLAVYLTVFNGAMTAGSLGWGAVGEAV 377 Query: 375 GLPAAHFLAAAGALAGIALTWRWKLQTGAGVDLAPSMHWPAPILAIDADADRGPVLITVE 434 G+ + + A G L + R KL G DL PS HWP P++A DRGPVLI +E Sbjct: 378 GIQSTLIIGAIGLLIAGLIMHRVKLPAG-DADLVPSNHWPEPLVAEPIAHDRGPVLILIE 436 Query: 435 YFIAPEKRDAFLAAVTELGRQRRSDGAYSWDVFEDAAESGRFLETFMVASWLEHLRQHQR 494 Y + + R AFL A+ L R+RR DGAY W V ED+A+ + +E FMV SW EHLRQH+R Sbjct: 437 YKVEKQHRTAFLHAIDHLSRERRRDGAYGWGVTEDSADPEKIVEWFMVESWAEHLRQHKR 496 Query: 495 VTNTDKVVQDAIREYGAAAE-PKVTHFI 521 V+N D +Q + Y + P V HF+ Sbjct: 497 VSNADADLQGKVLAYHVGPDKPVVRHFM 524 >SMa1814 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 530 Score = 363 bits (932), Expect = e-100, Method: Compositional matrix adjust. Identities = 238/522 (45%), Positives = 329/522 (63%), Gaps = 9/522 (1%) Query: 10 FRHTTFTVIWIATVVANVGTWMYNAASGWLMTSLDANPLTVSLVQVASSLPMFLFALPAG 69 R F V+WIAT+V N G+++ + AS WL+T L A P V++VQ A++LP+FL A+PAG Sbjct: 14 LRQKVFAVLWIATIVGNTGSFIRDVASSWLVTDLSAAPAAVAMVQAAATLPIFLLAIPAG 73 Query: 70 ALADTVDKRRFLIGCEIVLTIIAAASAALVGLN---LVTPPILLLFTFLLGAGAAFTAPA 126 L+D +D+R+FLI +++L AAAS L+ L+ L + L+ TF+ G GAA AP Sbjct: 74 VLSDILDRRKFLIVIQLLL---AAASICLMLLSATGLQSVSSLIALTFVGGIGAALMAPT 130 Query: 127 WQSVVPQLVPRQDLAAAVASNGVGVNISRAIGPALGGAVIGGLGIAAPFWINALSNFAVI 186 WQ++VP+LV RQD+ +AVA N +G+NISR+IGPA+GG ++ G A + ++ +S VI Sbjct: 131 WQAIVPELVARQDVKSAVALNSLGINISRSIGPAVGGLLLAWFGAAFTYGVDVISYVFVI 190 Query: 187 GALLWWRLASSQGNALPPERLAGAMVVGFRHARFNPKLRATLVRAATFFFFASAYWALLP 246 AL WWR A++ + L ER GA G R A+ + +L L+RAA FF FASA WALLP Sbjct: 191 VALTWWRRAATPDDVL-SERFFGAFRAGLRFAKASRELHVVLLRAAVFFAFASAVWALLP 249 Query: 247 LVARNQIAGGPALYGILLGAIGVGAVIGAFMLPWMKSTFGPNGLVAAGTVGTALSLILLG 306 LVAR+ + G YGILLGA+G GA+ GA +LP +++ F + L+ V TA + +L Sbjct: 250 LVARDLLDGDAGFYGILLGAVGAGAIGGALILPRLRTRFDADALLLGAAVVTAAVMAILS 309 Query: 307 IARYPEIGLAACLIAGVSWIAVLATINVSVQVSLPDWVRGRGLAIFVTAFFGAMTAGSVL 366 +A + A L G +WI L T+N + Q LP+WVRGR LA+++T F GAMTAGS+ Sbjct: 310 VAPPRWGAIVALLALGAAWITALTTLNGAAQAILPNWVRGRSLAVYLTVFNGAMTAGSLA 369 Query: 367 WGQLASGLGLPAAHFLAAAGALAGIALTWRWKLQTGAGVDLAPSMHWPAPILAIDADADR 426 WG +A L +P ++A G A L KL G DL S HWP P++A D DR Sbjct: 370 WGAVAEALNIPLTLNISAIGLAAAGLLFHFVKLPKGES-DLIASNHWPEPLVAALVDNDR 428 Query: 427 GPVLITVEYFIAPEKRDAFLAAVTELGRQRRSDGAYSWDVFEDAAESGRFLETFMVASWL 486 GPVLI +EY + +R FL A+ +L +RR DGAY W V EDAA+ R +E FMV SW Sbjct: 429 GPVLILIEYKVDKTERPDFLKALAKLSNERRRDGAYGWGVTEDAADPERIVEWFMVESWA 488 Query: 487 EHLRQHQRVTNTDKVVQDAIREYGAAAE-PKVTHFIAASFRQ 527 EHLRQH+RV+ D VQ +R + AE P V+H ++ + Q Sbjct: 489 EHLRQHRRVSKADADVQQEVRRFHKGAEAPVVSHLLSINRPQ 530