BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0155.0043.p (1034 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4207 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1158 0.0 PA4375 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1058 0.0 VC0164 [V] COG0841 Cation/multidrug efflux pump Vch Vibrio cholerae 1024 0.0 BMEI0893 [V] COG0841 Cation/multidrug efflux pump Bme Brucella m... 979 0.0 mlr3649 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobi... 956 0.0 >PA4207 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1029 Score = 1158 bits (2995), Expect = 0.0, Method: Compositional matrix adjust. Identities = 563/997 (56%), Positives = 760/997 (76%), Gaps = 1/997 (0%) Query: 1 MTFTELFIKRPVLSIVVSLLILLIGLRAAAVLPIRQYPKLSNTVVNITTSYPGASADMIQ 60 MTFT+LF++RPVL++VVS LILL+GL + LPIRQYP L ++ + +TT YPGASAD++Q Sbjct: 1 MTFTDLFVRRPVLALVVSTLILLLGLFSLGKLPIRQYPLLESSTITVTTEYPGASADLMQ 60 Query: 61 GFITTPLEQAVASAEGVDYVTSSSVLGASTIQVYIKLNFDPNEALTEVLSKVNSVKSLIP 120 GF+T P+ QAV+S EG+DY++S+SV G S + + + LN D +A+TE ++KVNSV+ +P Sbjct: 61 GFVTQPIAQAVSSVEGIDYLSSTSVQGRSVVTIRMLLNRDSTQAMTETMAKVNSVRYKLP 120 Query: 121 KESNDPIVTKSSGQATAVMYIAFSSEELTASAISDYLSRVVQPVLSTVDGVAAADILGSQ 180 + + D ++ +SSG+ TAV Y+ FSS+ L A++DYLSRVV+P+ S++DGVA G Q Sbjct: 121 ERAYDSVIERSSGETTAVAYVGFSSKTLPIPALTDYLSRVVEPMFSSIDGVAKVQTFGGQ 180 Query: 181 SFAMRLWLDAAKMAGHGVSPADVSAAIAANNFQAASGQTKGYFTISDVTTNTDLRSVDDF 240 AMRLWLDA ++AG G++ +DV+ AI NN+QAA G KG + +S+V NTDL +VDDF Sbjct: 181 RLAMRLWLDADRLAGRGLTASDVAEAIRRNNYQAAPGMVKGQYVLSNVRVNTDLTNVDDF 240 Query: 241 KRMVVKANDGGFVRMEDIAAVELAAQTTDVSVSMNGEHAVFIGVQASPQGNPLNIVRGVR 300 + MV++ + G VR+ D+ VEL A T+ S M+G+ AV +G+ +P GNPL IV G+R Sbjct: 241 REMVIRNDGNGLVRLRDVGTVELGAAATETSALMDGDPAVHLGLFPTPTGNPLVIVDGIR 300 Query: 301 ALFPEMERNLPPALKMKVAYDSTKFIQSSIDEVEKTLIEAVVIVVVVIFLFLASLRSVII 360 L PE+++ LPP +++ +AY++++FIQ+SIDEV +TL+EA++IVV+VI+L L SLRSV+I Sbjct: 301 KLLPEIQKTLPPDVRVDLAYETSRFIQASIDEVVRTLVEALLIVVLVIYLCLGSLRSVLI 360 Query: 361 PVVTIPLSLIGVCSMMLALGFSFNLLTLLAMVLAIGLVVDDAIVVVENVHRHLEEGAPPL 420 PV TIPLS++G ++MLA GFS NLLTLLAMVLAIGLVVDDAIVVVENVHRH+EEG P+ Sbjct: 361 PVATIPLSMLGAAALMLAFGFSVNLLTLLAMVLAIGLVVDDAIVVVENVHRHIEEGKSPV 420 Query: 421 QAAARGAREIVGPVVSMTITLAAVYAPIGFLGGVTGALFREFAFTLAGAVIVSGVIALTL 480 AA GARE+ GPV++MTITLAAVY PIG +GG+TGALFREFA TLAGAVIVSGV+ALTL Sbjct: 421 AAALIGAREVAGPVIAMTITLAAVYTPIGLMGGLTGALFREFALTLAGAVIVSGVVALTL 480 Query: 481 SPMMCSVCLKSAE-EGRFARVVNRVFGATTRWYGRKLDRSLDYRPITGLFALTMLGLVGF 539 SP+M S+ L++ + EGR R FG TR YG+ L+ SL +R +TG AL + + Sbjct: 481 SPVMSSLLLQAHQNEGRMGRAAEWFFGGLTRRYGQVLEFSLGHRWLTGGLALLVCISLPL 540 Query: 540 LYMHTSKELAPEEDQGIVFALTKAPKYANIDYLNYYGAKLEKAFQKFPETDLSFVLNGTS 599 LY +ELAP EDQ V KAP++AN+DY+ + KL++ + PET ++++NGT Sbjct: 541 LYSMPKRELAPTEDQAAVLTAIKAPQHANLDYVELFARKLDQVYTSIPETVSTWIINGTD 600 Query: 600 GSRGGMAGMLLKPWDERKRSSIALKSLVQVELSKIEGINAFAFSLPSLPGGTDGLPVQMV 659 G G+ L W++R+R + A++S +Q ++ +EG + FAF L +LPG T GLPVQMV Sbjct: 601 GPAASFGGINLAAWEKRERDASAIQSELQGKVGDVEGSSIFAFQLAALPGSTGGLPVQMV 660 Query: 660 INSTLGFQSVYEQMSNLKDAARKSGLFMVSDSDLEFNQPVVRIKVDRSKANDLGITMQNI 719 + S + +Y M +K AR+SGLF+V DSDL++N PVV++++DR+KAN LGI MQ+I Sbjct: 661 LRSPQDYPVLYRTMEEIKQKARQSGLFVVVDSDLDYNNPVVQVRIDRAKANSLGIRMQDI 720 Query: 720 GNALATLLGGNYVNHFNLQGRSYQVIPQVPREQRLAPEAIGNYYVKTAKGSMLPLSTVVS 779 G +LA L+G NYVN F ++GRSY VIPQ R+QR P+A+ +V+T G+++PLSTVV Sbjct: 721 GESLAVLVGENYVNRFGMEGRSYDVIPQSLRDQRFTPQALARQFVRTQDGNLVPLSTVVR 780 Query: 780 VETATDPNALTHYNQLNCATFQAVPMPGVTIGQAVDFLEAQAKKLPAGFSHDFLADARQY 839 V +PN L ++Q N AT QA+P PGV++GQAV FL+ A+ LPAGFSHD+ +D+RQY Sbjct: 781 VALQVEPNKLIQFDQQNAATLQAIPAPGVSMGQAVAFLDDVARGLPAGFSHDWQSDSRQY 840 Query: 840 VHEGNQLAITFAFALIVIFLVLAAQFESLRDPLVIMISVPMAIVGALIPLFLGWATINIY 899 EGN L F AL+VI+LVLAAQ+ESL DPL+I+I+VP++I GAL+PL LG+AT+NIY Sbjct: 841 TQEGNTLVFAFLAALVVIYLVLAAQYESLADPLIILITVPLSICGALLPLALGYATMNIY 900 Query: 900 TQVGLLTLVGLISKHGILMVEFANELQLKERLDRRSAIEMAARVRLRPILMTTAAMVTGL 959 TQ+GL+TL+GLISKHGILMVEFANELQL ERLDRR+AI AA++RLRP+LMTTAAMV GL Sbjct: 901 TQIGLVTLIGLISKHGILMVEFANELQLHERLDRRAAILRAAQIRLRPVLMTTAAMVFGL 960 Query: 960 IPLLTATGAGAASRFSIGLVLVAGMSIGTLFTLFVLP 996 +PLL A+GAGAASRF +G+V+V+GM +GTLFTLFVLP Sbjct: 961 VPLLFASGAGAASRFGLGVVIVSGMLVGTLFTLFVLP 997 >PA4375 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1018 Score = 1058 bits (2736), Expect = 0.0, Method: Compositional matrix adjust. Identities = 542/998 (54%), Positives = 734/998 (73%), Gaps = 4/998 (0%) Query: 1 MTFTELFIKRPVLSIVVSLLILLIGLRAAAVLPIRQYPKLSNTVVNITTSYPGASADMIQ 60 M FT+ FI+RPVL+ VVSLLI+L+G++A + L IR+YP++ N ++ +TT Y GA+A+ IQ Sbjct: 1 MAFTDPFIRRPVLASVVSLLIVLLGMQAFSKLVIREYPQMENALITVTTLYAGANAETIQ 60 Query: 61 GFITTPLEQAVASAEGVDYVTSSSVLGASTIQVYIKLNFDPNEALTEVLSKVNSVKSLIP 120 G+IT PL+Q++ASAEG+DY+TS S STI +Y ++ + + +TE+L+K N VKS +P Sbjct: 61 GYITQPLQQSLASAEGIDYMTSVSRQNYSTISIYARIGANTDRLVTELLAKSNEVKSQLP 120 Query: 121 KESNDPIVTKSSGQATAVMYIAFSSEELTASAISDYLSRVVQPVLSTVDGVAAADILGSQ 180 ++ DP++ K + A+A+MYI+F SE++ I+DYLSRV+QP L+T+ G+A A+ILG+Q Sbjct: 121 PDAEDPVLQKEAADASALMYISFYSEQMNNPQITDYLSRVIQPKLATLPGIAEAEILGNQ 180 Query: 181 SFAMRLWLDAAKMAGHGVSPADVSAAIAANNFQAASGQTKGYFTISDVTTNTDLRSVDDF 240 FAMRLWLD KMA GV+ +++ A+ NF AA+G+ KG ++ V +TDL+S F Sbjct: 181 VFAMRLWLDPVKMAAFGVTAGEINQAVQQYNFLAAAGEVKGQLVVTSVNASTDLKSPQAF 240 Query: 241 KRMVVKANDGGFVRMEDIAAVELAAQTTDVSVSMNGEHAVFIGVQASPQGNPLNIVRGVR 300 + VK + V M D+A VEL A + D S NG +V+IG++ +P NPL++++ VR Sbjct: 241 AAIPVKTDGDRRVLMGDVARVELGAASYDAISSFNGIPSVYIGIKGTPSANPLDVIKEVR 300 Query: 301 ALFPEMERNLPPALKMKVAYDSTKFIQSSIDEVEKTLIEAVVIVVVVIFLFLASLRSVII 360 A PE+E LPP LK+ +AYD+T+FIQ+SIDEV KTL EAV+IV+VV+FLFL + RSV+I Sbjct: 301 AKMPELEEQLPPNLKVSIAYDATRFIQASIDEVVKTLGEAVLIVIVVVFLFLGAFRSVLI 360 Query: 361 PVVTIPLSLIGVCSMMLALGFSFNLLTLLAMVLAIGLVVDDAIVVVENVHRHLEEGAPPL 420 PVVTIPLS+IGV M A+G+S NLLTLLAMVLAIGLVVDDAIVVVEN+HRH+EEG PP Sbjct: 361 PVVTIPLSMIGVLFFMQAMGYSINLLTLLAMVLAIGLVVDDAIVVVENIHRHIEEGKPPF 420 Query: 421 QAAARGAREIVGPVVSMTITLAAVYAPIGFLGGVTGALFREFAFTLAGAVIVSGVIALTL 480 +AA GAREI PVVSMTITLAAVYAPIGFL G+TGALF+EFAFTLAGAVI+SG++ALTL Sbjct: 421 EAALEGAREIAVPVVSMTITLAAVYAPIGFLTGLTGALFKEFAFTLAGAVIISGIVALTL 480 Query: 481 SPMMCSVCLKSAEE-GRFARVVNRVFGATTRWYGRKLDRSLDYRPITGLFALTMLGLVGF 539 SPMMCS L+ E A ++ +F + Y R L +LD RP+ +FA+ +L L+ Sbjct: 481 SPMMCSRLLRHEENPSGLAHRLDLIFEGLKQRYQRALHGTLDTRPVVLVFAVLVLALIPV 540 Query: 540 LYMHTSKELAPEEDQGIVFALTKAPKYANIDYLNYYGAKLEKAFQKFPETDLSFVLNGTS 599 L M T KELAPEEDQGIVF +T +P+ AN+DYLN Y A+ E F+ FPE +F +NG + Sbjct: 541 LLMFTKKELAPEEDQGIVFLMTNSPQTANLDYLNRYTAEFEGIFRSFPEYYSAFQINGYN 600 Query: 600 GSRGGMAGMLLKPWDERKRSSIALKSLVQVELSKIEGINAFAFSLPSLPGGTDGLPVQMV 659 G + G+ GMLLKPWDER++S + L VQ +L++I G+ FAF+LPSLPG +GLP Q V Sbjct: 601 GVQAGIGGMLLKPWDEREKSQMELLHAVQAKLNEIPGVQIFAFNLPSLPGTGEGLPFQFV 660 Query: 660 INSTLGFQSVYEQMSNLKDAARKSGLFMVSDSDLEFNQPVVRIKVDRSKANDLGITMQNI 719 +N+ ++S+ + +K A +SG F D DL F++P + + +DR KA +G++MQ++ Sbjct: 661 LNTANDYESLLQVAQRVKQRASESGKFAFLDLDLAFDKPELVVDIDREKAAQMGVSMQDL 720 Query: 720 GNALATLLGGNYVNHFNLQGRSYQVIPQVPREQRLAPEAIGNYYVKTAKGSMLPLSTVVS 779 G ALA+LLG +N F + GRSY+VI QV R R P +G+YYVK+ G ++ LST++ Sbjct: 721 GVALASLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLGSYYVKSRNGQLVALSTLIE 780 Query: 780 VETATDPNALTHYNQLNCATFQAVPMPGVTIGQAVDFLEAQAK-KLPAGFSHDFLADARQ 838 P L + QLN A P+ V++G+A++ ++ A+ + P GF+ D+ +RQ Sbjct: 781 THERARPRQLNQFQQLNSAIISGFPI--VSMGEAIETVQQIAREEAPRGFAVDYAGASRQ 838 Query: 839 YVHEGNQLAITFAFALIVIFLVLAAQFESLRDPLVIMISVPMAIVGALIPLFLGWATINI 898 YV EG+ L +TF AL +IFLVLAAQFES RDPLVIM++VP++I GALIPLFLG +++NI Sbjct: 839 YVQEGSALLVTFGLALAIIFLVLAAQFESFRDPLVIMVTVPLSICGALIPLFLGVSSLNI 898 Query: 899 YTQVGLLTLVGLISKHGILMVEFANELQLKERLDRRSAIEMAARVRLRPILMTTAAMVTG 958 YTQVGL+TL+GLISKHGIL+VEFAN+L+ ++ L RR AIE AA +RLRP+LMTTAAMV G Sbjct: 899 YTQVGLVTLIGLISKHGILIVEFANQLRHEQGLGRREAIEQAAAIRLRPVLMTTAAMVLG 958 Query: 959 LIPLLTATGAGAASRFSIGLVLVAGMSIGTLFTLFVLP 996 +IPL+ ATGAGA SRF IG+V+ GMS+GTLFTLFVLP Sbjct: 959 VIPLILATGAGAVSRFDIGIVIATGMSVGTLFTLFVLP 996 >VC0164 [V] COG0841 Cation/multidrug efflux pump Vch Vibrio cholerae Length = 1036 Score = 1024 bits (2647), Expect = 0.0, Method: Compositional matrix adjust. Identities = 517/1015 (50%), Positives = 703/1015 (69%), Gaps = 14/1015 (1%) Query: 1 MTFTELFIKRPVLSIVVSLLILLIGLRAAAVLPIRQYPKLSNTVVNITTSYPGASADMIQ 60 M FT++FIKRPVL++ +S LI+L+GL+A + +R+YP+++NTV+ ++T Y GASAD+IQ Sbjct: 1 MRFTDVFIKRPVLAVSISFLIVLLGLQAIFKMQVREYPEMTNTVITVSTGYYGASADLIQ 60 Query: 61 GFITTPLEQAVASAEGVDYVTSSSVLGASTIQVYIKLNFDPNEALTEVLSKVNSVKSLIP 120 GFIT PLEQAVA A+ +D++TS SVLG STI V +KLN DPN AL++VL+K NSV+S +P Sbjct: 61 GFITQPLEQAVAQADNIDFMTSQSVLGRSTITVTMKLNTDPNAALSDVLAKTNSVRSQLP 120 Query: 121 KESNDPIVTKSSGQATAVMYIAFSSEELTASAISDYLSRVVQPVLSTVDGVAAADILGSQ 180 KE+ DP VT S+G TAV+YI F+S EL +S I+DYL RVV P L V+GV++ D+ G Sbjct: 121 KEAEDPTVTMSTGSTTAVLYIGFTSNELASSQITDYLERVVNPQLYAVNGVSSIDLYGGM 180 Query: 181 SFAMRLWLDAAKMAGHGVSPADVSAAIAANNFQAASGQTKGYFTISDVTTNTDLRSVDDF 240 +A+R+WLD AKMA +S ADV + + ANN+Q+A+GQ G F + + + +T + +V+D Sbjct: 181 KYALRVWLDPAKMAALNLSAADVMSILNANNYQSATGQAIGEFVLYNGSADTQVSTVEDL 240 Query: 241 KRMVVKANDGGFVRMEDIAAVELAAQTTDVSVSMNGEHAVFIGVQASPQGNPLNIVRGVR 300 + +VVKA G R+ DIA V LA S NG AV + A+P NP+NI + V Sbjct: 241 ESLVVKAEKGTVTRLGDIAKVTLAKSHDTYRASANGREAVVAAINAAPSANPINIAKDVL 300 Query: 301 ALFPEMERNLPPALKMKVAYDSTKFIQSSIDEVEKTLIEAVVIVVVVIFLFLASLRSVII 360 + PE+++N+P ++M V YDST I SI EV KT++EA +IV+VVI LFL SLR+V+I Sbjct: 301 EMLPELQKNMPSNIEMNVLYDSTVAINESIHEVIKTIVEAALIVLVVITLFLGSLRAVLI 360 Query: 361 PVVTIPLSLIGVCSMMLALGFSFNLLTLLAMVLAIGLVVDDAIVVVENVHRHLEEGAPPL 420 P+VTIPLSLIGV +M +GFS+NL+TLLAMVLAIGLVVDDAIVV+ENV RH++EG P Sbjct: 361 PIVTIPLSLIGVAMVMQMMGFSWNLMTLLAMVLAIGLVVDDAIVVLENVDRHIKEGESPF 420 Query: 421 QAAARGAREIVGPVVSMTITLAAVYAPIGFLGGVTGALFREFAFTLAGAVIVSGVIALTL 480 +AA G REI PV++MT+TL AVYAPI +GG+TG+LF+EFA TLAG+V VSG++ALTL Sbjct: 421 RAAIIGTREIAIPVIAMTLTLGAVYAPIALMGGITGSLFKEFALTLAGSVFVSGIVALTL 480 Query: 481 SPMMCSVCLKSAEE-GRFARVVNRVFGATTRWYGRKLDRSLDYRPITGLFALTMLGLVGF 539 SPMMCS LK+ E +F V+ + T Y R L + +RP+ FA + + Sbjct: 481 SPMMCSKMLKANEAPNKFELKVHHLLDRMTARYERMLTAVMAHRPVVIAFAFIVFASLPM 540 Query: 540 LYMHTSKELAPEEDQGIVFALTKAPKYANIDYLNYYGAKLEKAFQKFPETDLSFVLNGTS 599 L+ ELAP ED+G++ + P AN+DYL + K PE + V G Sbjct: 541 LFKFIPSELAPSEDKGVIMLMGTGPSNANLDYLANTMDDVNKILSDQPEVQFAQVFTGVP 600 Query: 600 GSRG--GMAGMLLKPWDERKRSSIALKSLVQVELSKIEGINAFAFSLPSLPGGTDGLPVQ 657 S G+A M+ PW +R+ S + + V + I G+ AF +P LPG GLP+Q Sbjct: 601 NSNQAFGIASMV--PWSQREASQATVTNRVGTLVQDIPGMAVTAFQMPELPGAGSGLPIQ 658 Query: 658 MVINSTLGFQSVYEQMSNLKDAARKSGLFMVSDSDLEFNQPVVRIKVDRSKANDLGITMQ 717 VI + F+S++ +++ + + +F+ SD DL F+ ++I +D+ KA G+TMQ Sbjct: 659 FVITTPSNFESLFTIATDVLTEVKANPMFVYSDLDLNFDSATMKINIDKDKAGAYGVTMQ 718 Query: 718 NIGNALATLLGGNYVNHFNLQGRSYQVIPQVPREQRLAPEAIGNYYVKTAKGSMLPLSTV 777 +IG L+T++ YVN +L GRSY+VIPQV R+ RL PE++ +YYV+ A G ++PL ++ Sbjct: 719 DIGITLSTMMADGYVNRIDLNGRSYEVIPQVERKWRLNPESMNSYYVRAADGKVIPLGSL 778 Query: 778 VSVETATDPNALTHYNQLNCATFQAVPMPGVTIGQAVDFLEAQA-KKLPAGFSHDFLADA 836 V+++ +P +L H+NQLN AT AVP PG +G A+++ E A KLP G+SHD++ +A Sbjct: 779 VTIDVVAEPRSLPHFNQLNSATVGAVPAPGTAMGDAINWFENLASSKLPKGYSHDYMGEA 838 Query: 837 RQYVHEGNQLAITFAFALIVIFLVLAAQFESLRDPLVIMISVPMAIVGALIPLFLGWATI 896 RQYV EG+ L TF AL +IFLVLA QFESLRDPLVIM+SVP+AI GALI L G AT+ Sbjct: 839 RQYVTEGSALYATFGLALAIIFLVLAIQFESLRDPLVIMVSVPLAICGALIALAWGTATM 898 Query: 897 NIYTQVGLLTLVGLISKHGILMVEFANELQLKERLDRRSAIEMAARVRLRPILMTTAAMV 956 NIY+QVGL+TLVGLI+KHGIL+ E A E QL +L R A+ AA+VRLRPILMTTAAM+ Sbjct: 899 NIYSQVGLITLVGLITKHGILICEVAKEEQLHNKLSRIEAVMHAAKVRLRPILMTTAAMI 958 Query: 957 TGLIPLLTATGAGAASRFSIGLVLVAGMSIGTLFTLFVLP--------KKKKXPI 1003 GLIPL+ ATGAGAA RFSIG+V+V+G++IGTLFTLFVLP K K P+ Sbjct: 959 AGLIPLMYATGAGAAQRFSIGIVIVSGLAIGTLFTLFVLPVIYSYLAEKHKPLPV 1013 >BMEI0893 [V] COG0841 Cation/multidrug efflux pump Bme Brucella melitensis Length = 1029 Score = 979 bits (2531), Expect = 0.0, Method: Compositional matrix adjust. Identities = 498/998 (49%), Positives = 700/998 (70%), Gaps = 2/998 (0%) Query: 1 MTFTELFIKRPVLSIVVSLLILLIGLRAAAVLPIRQYPKLSNTVVNITTSYPGASADMIQ 60 M F+++FI+RPVL+ VVSL+I+L+GL+ A L +R+YPK+ TV+ +TT+Y GASAD+IQ Sbjct: 1 MNFSDIFIRRPVLATVVSLMIVLLGLQGIAQLSVREYPKVDETVITVTTAYAGASADLIQ 60 Query: 61 GFITTPLEQAVASAEGVDYVTSSSVLGASTIQVYIKLNFDPNEALTEVLSKVNSVKSLIP 120 GFIT P+ +AVA+ E +DYVTSSS +ST+ V +KL DP+ ALTEV++KVN V+ +P Sbjct: 61 GFITAPIAEAVATTENIDYVTSSSRPSSSTVTVQMKLGADPDAALTEVIAKVNQVRGNLP 120 Query: 121 KESNDPIVTKSSGQATAVMYIAFSSEELTASAISDYLSRVVQPVLSTVDGVAAADILGSQ 180 ES+DP++ K +GQ+ A MY+A + +T+ I++YL RV+QP +ST+ GVA A+ILG Q Sbjct: 121 DESDDPVIVKGTGQSFATMYLAAQNPNMTSEQITEYLKRVIQPRMSTIQGVAKAEILGGQ 180 Query: 181 SFAMRLWLDAAKMAGHGVSPADVSAAIAANNFQAASGQTKGYFTISDVTTNTDLRSVDDF 240 ++MR+WLD ++A ++ +V +AI A+NF +A G+TK + + +T + L++ + F Sbjct: 181 VYSMRVWLDPIQLAARQITAPEVLSAIKASNFLSAPGKTKNEYVATSITLKSTLQTPEAF 240 Query: 241 KRMVVKANDGGFVRMEDIAAVELAAQTTDVSVSMNGEHAVFIGVQASPQGNPLNIVRGVR 300 M +KA VR+ D+A VELAA++TD VS NG F+GV +P NP+++ VR Sbjct: 241 GAMPIKALGDEVVRLRDVAKVELAAESTDTIVSFNGSAGTFLGVYPTPAANPIDMAAAVR 300 Query: 301 ALFPEMERNLPPALKMKVAYDSTKFIQSSIDEVEKTLIEAVVIVVVVIFLFLASLRSVII 360 P ++ +LP + + + YD+T+ I SSI+EV T+ EAV IV++VI +FL S RSV+I Sbjct: 301 KELPSIQASLPEGMSLVLVYDATEQISSSINEVFTTIGEAVAIVILVIIVFLGSFRSVLI 360 Query: 361 PVVTIPLSLIGVCSMMLALGFSFNLLTLLAMVLAIGLVVDDAIVVVENVHRHLEEGAPPL 420 P+VTIP+SLIGVC + LGFS NLL+LLAMVLAIGLVVDDAIVV+EN+HRH+EEG P+ Sbjct: 361 PIVTIPISLIGVCFFLYVLGFSINLLSLLAMVLAIGLVVDDAIVVLENIHRHIEEGLHPI 420 Query: 421 QAAARGAREIVGPVVSMTITLAAVYAPIGFLGGVTGALFREFAFTLAGAVIVSGVIALTL 480 AA +G +EI G +V+MTITLAAV+ P+GF GG+TG+LFREFAFTLAGAVI+SG+ ALT+ Sbjct: 421 DAAFKGMKEITGSIVAMTITLAAVFTPLGFTGGLTGSLFREFAFTLAGAVIISGIAALTI 480 Query: 481 SPMMCSVCLKSAEEGRFARVVNRVFGATTRWYGRKLDRSLDYRPITGLFALTMLGLVGFL 540 SPMMCS LK ++ RF + ++R F +WY ++ SL+YR IT L ++GL GFL Sbjct: 481 SPMMCSRMLKHGDQTRFQKFIDRTFSRFEKWYHARVSNSLNYRWITLAIVLCLMGLTGFL 540 Query: 541 YMHTSKELAPEEDQGIVFALTKAPKYANIDYLNYYGAKLEKAFQKFPETDLSFVLNGTS- 599 +M+TS ELAPEED G +F++ +AP+YA Y N Y +++ + PE F + G Sbjct: 541 FMNTSSELAPEEDSGALFSMFQAPQYATSAYTNLYAEQIDALTKDLPEQKTRFQIVGMDG 600 Query: 600 GSRGGMAGMLLKPWDERKRSSIALKSLVQVELSKIEGINAFAFSLPSLPGGTDGLPVQMV 659 G+ G+A +LK W+ER RS ++ + +SK+ G+ AF F+ PSLPG GLP+ + Sbjct: 601 GTTSGIALWVLKDWNERDRSQKQIQQDLTARISKVAGVQAFIFAPPSLPGTGGGLPISIA 660 Query: 660 INSTLGFQSVYEQMSNLKDAARKSGLFMVSDSDLEFNQPVVRIKVDRSKANDLGITMQNI 719 + ST V+ +K A+ SG F++ + L FN P I +DR +A LG+ + +I Sbjct: 661 LQSTGPADQVFALAEEIKAEAQASGQFIIVQNSLSFNAPQTTITIDRDRAATLGVQVSDI 720 Query: 720 GNALATLLGGNYVNHFNLQGRSYQVIPQVPREQRLAPEAIGNYYVKTAKGSMLPLSTVVS 779 G+ L L GG + F+ SY +I QVP R PE +GN+YV++ GSM+PLS+V+ Sbjct: 721 GSTLGLLTGGASIAKFDRDSNSYDIITQVPDSYRANPEMLGNFYVRSVSGSMVPLSSVIQ 780 Query: 780 VETATDPNALTHYNQLNCATFQAVPMPGVTIGQAVDFLEAQAK-KLPAGFSHDFLADARQ 838 + P A+ +NQLN AT A+P+PGVT GQ + L A+ K+P GF D+ +R Sbjct: 781 INENAAPAAIEQFNQLNSATISALPLPGVTTGQGLQTLVDIARSKMPEGFFLDYSCQSRL 840 Query: 839 YVHEGNQLAITFAFALIVIFLVLAAQFESLRDPLVIMISVPMAIVGALIPLFLGWATINI 898 V +GN + I F FA+ VI+LVLAAQFES RDP +IM+SVP++I GA++PL +G T+NI Sbjct: 841 EVEQGNTILIAFGFAVFVIYLVLAAQFESFRDPFIIMMSVPLSIFGAIVPLNIGLGTLNI 900 Query: 899 YTQVGLLTLVGLISKHGILMVEFANELQLKERLDRRSAIEMAARVRLRPILMTTAAMVTG 958 YTQVGL+TLVGLI+KHGILMVEFAN+ + L RR AI +AA RLRPILMTTAAM G Sbjct: 901 YTQVGLITLVGLITKHGILMVEFANQQRRLHGLSRRDAIVVAAETRLRPILMTTAAMALG 960 Query: 959 LIPLLTATGAGAASRFSIGLVLVAGMSIGTLFTLFVLP 996 ++PL+ ATGAGAA+R+S+GLV+ G++IGT+FTLFV+P Sbjct: 961 VVPLIIATGAGAAARYSMGLVIFTGITIGTIFTLFVVP 998 >mlr3649 [V] COG0841 Cation/multidrug efflux pump Mlo Mesorhizobium loti Length = 1027 Score = 956 bits (2470), Expect = 0.0, Method: Compositional matrix adjust. Identities = 485/1001 (48%), Positives = 690/1001 (68%), Gaps = 7/1001 (0%) Query: 1 MTFTELFIKRPVLSIVVSLLILLIGLRAAAVLPIRQYPKLSNTVVNITTSYPGASADMIQ 60 M+F++LFI+RPVLS V+ LILL+G + L IRQYPK+ T + ITT+YPGASAD+IQ Sbjct: 1 MSFSDLFIRRPVLSTVLGCLILLLGFQGIFNLSIRQYPKVDETAITITTAYPGASADLIQ 60 Query: 61 GFITTPLEQAVASAEGVDYVTSSSVLGASTIQVYIKLNFDPNEALTEVLSKVNSVKSLIP 120 GFI+ P+ +AVAS E +DYVTSSS +ST+ V +KL +P+ ALTEVLSKV V+ +P Sbjct: 61 GFISAPIARAVASTENIDYVTSSSRPSSSTVTVQMKLGSNPDVALTEVLSKVQGVRGTLP 120 Query: 121 KESNDPIVTKSSGQATAVMYIAFSSEELTASAISDYLSRVVQPVLSTVDGVAAADILGSQ 180 S DP++ K +GQ A+MYI+ + +T +++Y+ RV++P +STV+GVA I G+Q Sbjct: 121 DASKDPVIVKGTGQQFAMMYISMQNPNMTKEQLTEYIERVIRPRMSTVEGVADVQIFGAQ 180 Query: 181 SFAMRLWLDAAKMAGHGVSPADVSAAIAANNFQAASGQTKGYFTISDVTTNTDLRSVDDF 240 ++MR+W+D ++A GV+ A+V AI +NF +A G T+ + +S ++ + L++ + F Sbjct: 181 EYSMRVWIDPIRLAARGVTAAEVLTAINNSNFLSAPGNTQNEYVVSSISVRSTLQTPEAF 240 Query: 241 KRMVVKANDGGFVRMEDIAAVELAAQTTDVSVSMNGEHAVFIGVQASPQGNPLNIVRGVR 300 + +++ DG VR+ D+A VEL A TD VS NG+ F+ + +P NPL + Sbjct: 241 AELPLRSTDGNVVRLRDVARVELGAANTDTRVSFNGKPGTFLAIFPTPAANPLTTAAALT 300 Query: 301 ALFPEMERNLPPALKMKVAYDSTKFIQSSIDEVEKTLIEAVVIVVVVIFLFLASLRSVII 360 L P+++ LP + ++V YD+T I +SI+EV KT+ EAV IVVVVI LFL S RSV++ Sbjct: 301 KLVPQIQETLPKGMTIEVVYDATGQISASIEEVFKTIGEAVAIVVVVILLFLGSFRSVMM 360 Query: 361 PVVTIPLSLIGVCSMMLALGFSFNLLTLLAMVLAIGLVVDDAIVVVENVHRHLEEGA-PP 419 P++TIPLSLIGVC ++ A+G+S NLL+LLAMVLAIGLVVDDAIVVVEN+HRH+EE P Sbjct: 361 PIITIPLSLIGVCFLLFAVGYSINLLSLLAMVLAIGLVVDDAIVVVENIHRHMEEDHMTP 420 Query: 420 LQAAARGAREIVGPVVSMTITLAAVYAPIGFLGGVTGALFREFAFTLAGAVIVSGVIALT 479 +QAA G REI +V+MT+TLAAV+AP+ F GG+TGALFREFA TLAG+V++SGVIA+T Sbjct: 421 MQAAFSGMREIASAIVAMTMTLAAVFAPLAFTGGLTGALFREFAVTLAGSVVLSGVIAVT 480 Query: 480 LSPMMCSVCLKSAEEGRFARVVNRVFGATTRWYGRKLDRSLDYRPITGLFALTMLGLVGF 539 ++PMM + LK+ GRF R+V+ +F Y R + SL+YRP+T + L ++G+ GF Sbjct: 481 ITPMMSARLLKAGTPGRFQRIVDGIFARVEHVYERAVTGSLNYRPLTLIIVLALVGVTGF 540 Query: 540 LYMHTSKELAPEEDQGIVFALTKAPKYANIDYLNYYGAKLEKAFQKFPETDLSF---VLN 596 ++ TS ELAPEEDQG + +L AP YA DY Y ++ + PET F Sbjct: 541 MFTKTSSELAPEEDQGFLLSLVTAPTYATSDYTETYVNQMLGLVRDIPETRAQFSAVAFG 600 Query: 597 GTSGSRGGMAGMLLKPWDERKRSSIALKSLVQVELSKIEGINAFAFSLPSLPGGTDGLPV 656 GT+ S G K W ERKR+S L++ + L+K+ G+ AF F+ P+LPG GLP+ Sbjct: 601 GTTNS--AFVGFAFKDWAERKRNSKELQADITARLAKVAGVQAFVFAPPTLPGSGGGLPI 658 Query: 657 QMVINSTLGFQSVYEQMSNLKDAARKSGLFMVSDSDLEFNQPVVRIKVDRSKANDLGITM 716 +V+ ST VY+ +K+ A+ SG F+V + + ++ P V + +DR +A L + + Sbjct: 659 ALVVRSTGDSAEVYKAAEQIKNKAQASGRFIVVQNSMSYDSPQVTVTIDRDRAAALNLPI 718 Query: 717 QNIGNALATLLGGNYVNHFNLQGRSYQVIPQVPREQRLAPEAIGNYYVKTAKGSMLPLST 776 +IG L L+GG V F+ SY +IPQVP++ R PE +G Y+V++ G M+PLS Sbjct: 719 ADIGRTLTLLVGGAEVAQFDRDSNSYDIIPQVPQQFRDNPERLGEYFVRSVTGEMVPLSA 778 Query: 777 VVSVETATDPNALTHYNQLNCATFQAVPMPGVTIGQAVDFLEAQAKK-LPAGFSHDFLAD 835 VV++ P A+ +NQLN +T A+P+PGVT G + LE A++ LP F D+ Sbjct: 779 VVNISNNASPAAIEQFNQLNSSTISALPLPGVTTGDGLKVLEDIARESLPDTFFIDYSGQ 838 Query: 836 ARQYVHEGNQLAITFAFALIVIFLVLAAQFESLRDPLVIMISVPMAIVGALIPLFLGWAT 895 +RQ +GN + I FA A+IVI+LVLAAQFES RDPL+IM++VP++I GA++PL LG T Sbjct: 839 SRQEKEQGNTILIAFAAAVIVIYLVLAAQFESFRDPLIIMMAVPLSIFGAIVPLNLGLGT 898 Query: 896 INIYTQVGLLTLVGLISKHGILMVEFANELQLKERLDRRSAIEMAARVRLRPILMTTAAM 955 +NIYTQVGL+TL+GLI+KHGIL+VEFAN+ + + RR AI +A+VRLRPILMTTAAM Sbjct: 899 LNIYTQVGLITLIGLITKHGILLVEFANQQREAHGMRRRDAIIASAKVRLRPILMTTAAM 958 Query: 956 VTGLIPLLTATGAGAASRFSIGLVLVAGMSIGTLFTLFVLP 996 G++PL+T++GAGAA+R+S+GLV+ G+ +GT+FTLFV+P Sbjct: 959 ALGVVPLITSSGAGAAARYSMGLVIFTGILVGTMFTLFVVP 999