BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0155.0041.p (380 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1221 [GEPR] COG0477 Permeases of the major facilitator superf... 238 2e-62 AGc4938 [GEPR] COG0477 Permeases of the major facilitator superf... 157 4e-38 SMc03889 [GEPR] COG0477 Permeases of the major facilitator super... 156 9e-38 PA3532 [GEPR] COG0477 Permeases of the major facilitator superfa... 152 2e-36 BMEI0267 [GEPR] COG0477 Permeases of the major facilitator super... 142 1e-33 >YPO1221 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 384 Score = 238 bits (606), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 167/363 (46%), Positives = 231/363 (63%), Gaps = 1/363 (0%) Query: 14 TRLAFFVAGFGLAAWAPLVPLAKERLAVDDRMLGLLLLCLGMGSVLAMLLTSVSNARYGS 73 TRLAFF+AG G+AAWAPLVP AK R+ ++D LGLLLLC+G+GS+LAM LT V A++G Sbjct: 20 TRLAFFIAGLGMAAWAPLVPFAKARIGLNDASLGLLLLCIGIGSMLAMPLTGVLTAKWGC 79 Query: 74 KPIIFVGGLGLALILPWLAIAGTPLALGATLFAFGVSLGAIDVAMNIYAIELERATGRPL 133 + +I + G L L LP L + TP + L FG ++G IDVAMNI A+ +E+A+GR + Sbjct: 80 RAVILLAGAVLCLDLPLLVLMNTPATMAIALLVFGAAMGIIDVAMNIQAVIVEKASGRAM 139 Query: 134 MSGFHAHYSIGEFTGSAAVTLFLSLQLGPLFSTLVCSMFMMIAIVSAWPRLTATSVR-QQ 192 MSGFH +S+G G+ V+ L L L PL + + + M+I +++A L S Sbjct: 140 MSGFHGLFSVGGIVGAGGVSALLWLGLNPLTAIMATVVLMIILLLAANKNLLRGSGEPHD 199 Query: 193 GPVFVLPHRSVVLIAALAAITFLVEGAMLDWSALLLVGQDLLAEAHGGLGCMLFAIAMTA 252 GP+FV P V+ I L + FL EG+MLDWSA+ L ++ + G+G +FAIAMT Sbjct: 200 GPLFVFPRGWVMFIGFLCFVMFLAEGSMLDWSAVFLTTLRGMSPSQAGMGYAVFAIAMTL 259 Query: 253 GRLGGDAVVERIGDRATLMLGTLPIMIGFLAVVAAPVAVIAMAGFLLIGLGISNVVPVLC 312 GRL GD +V +G L+ G+L IG + ++ ++ A+ GF+L+G G SNVVP+L Sbjct: 260 GRLNGDRIVNGLGRYKVLLGGSLCSAIGIIIAISIDSSMAAIIGFMLVGFGASNVVPILF 319 Query: 313 RRAGKQKVMPVGVAIAVITTAGYAGILMGPASIGLVAHMTGLPFAFGMLGALMCIVTLSA 372 AG Q VMP +A+A ITT GYAGIL GPA+IG +A ++ L AFG + L+ V SA Sbjct: 320 TAAGNQTVMPANLAVASITTIGYAGILAGPAAIGFIAQLSSLSVAFGCVALLLLTVAASA 379 Query: 373 RMV 375 R V Sbjct: 380 RAV 382 >AGc4938 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 398 Score = 157 bits (396), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 119/353 (33%), Positives = 190/353 (53%), Gaps = 10/353 (2%) Query: 12 LGTRLAFFVAGFGLAAWAPLVPLAKERLAVDDRMLGLLLLCLGMGSVLAMLLTSVSNARY 71 LG L F + GF + +WAP +P RL++ + LGL++L G+GS++ M + AR+ Sbjct: 24 LGVSLLFLMNGFMMGSWAPKIPEFAARLSLSESALGLIILVFGIGSLVFMPIAGSQIARF 83 Query: 72 GSKPIIFVGGLGLALILP---WLAIAGTPLALGATLFAFGVSLGAIDVAMNIYAIELERA 128 GS+ + V A+ LP +++ AGT A +F FG GA+DVAMN A+ +ER Sbjct: 84 GSRTVSLVTA---AIFLPTLLFISWAGTVWAGVIAVFLFGGLTGAMDVAMNANAVAVERD 140 Query: 129 TGRPLMSGFHAHYSIGEFTGSAAVTLFLSLQLGPLFSTLVCSMFMMIAIVSAWPRLTAT- 187 R +MS HA +S+G G+ ++ +G + ++ ++ +V AWPR+ A Sbjct: 141 MRRAIMSSCHAFWSLGGLIGAGLGGYLIT-AIGVQGHAIALTIIALVLLVIAWPRVLADR 199 Query: 188 -SVRQQGPVFVLPHRSVVLIAALAAI-TFLVEGAMLDWSALLLVGQDLLAEAHGGLGCML 245 ++ P LP + I L A+ + + EGA+LDW AL L + + + G Sbjct: 200 PHPEEERPKGGLPLTPLPWIIGLMALFSMIPEGAILDWGALYLRNELGASVSQSGFAFAA 259 Query: 246 FAIAMTAGRLGGDAVVERIGDRATLMLGTLPIMIGFLAVVAAPVAVIAMAGFLLIGLGIS 305 F++ M A R GD V ++ G TL + +IG + A + IA+ GF + G+GIS Sbjct: 260 FSMTMAAMRFAGDLVRDKFGAVNTLRFCSAMSIIGLIIAGVAGNSTIAIIGFAIAGIGIS 319 Query: 306 NVVPVLCRRAGKQKVMPVGVAIAVITTAGYAGILMGPASIGLVAHMTGLPFAF 358 N+VP+ AG + G+ ++V+TT GY+GIL+ P++IG +A TGL F Sbjct: 320 NMVPIAFSAAGNMPGLAPGIGLSVVTTMGYSGILVAPSAIGFIAEHTGLASVF 372 >SMc03889 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 379 Score = 156 bits (394), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 124/366 (33%), Positives = 192/366 (52%), Gaps = 12/366 (3%) Query: 12 LGTRLAFFVAGFGLAAWAPLVPLAKERLAVDDRMLGLLLLCLGMGSVLAMLLTSVSNARY 71 L L F + GF +WAP +P KERL + + +LGLL+L G+GS++ M + AR Sbjct: 6 LAVSLLFLMNGFVTGSWAPKIPEFKERLGIGESVLGLLILGFGIGSLVLMPIAGGFIARL 65 Query: 72 GSKPIIFVGGLGLALILPWLAIAGTPLALGATLFAFGVSLGAIDVAMNIYAIELERATGR 131 GS+ ++ V + L+ +L L + +F G +GA+DVAMN A+E+E++ R Sbjct: 66 GSQKVVKVTAIILSPLLLLLTLLPNLWTAALGMFLLGGFVGAMDVAMNANAVEVEKSMRR 125 Query: 132 PLMSGFHAHYSIGEFTGSAAVTLFLSLQLGPLFSTLVCSMFMMIAIVSAWPRL------- 184 +MS HA++S+G A + FL + G L +V + + + AWP + Sbjct: 126 AIMSSCHAYWSLGGLI-GAGIGGFLMARFGVLPHAIVVTCLCLAILAVAWPMILADRPHP 184 Query: 185 TATSVRQQGPVFVLPHRSVVLIAALAAITFLVEGAMLDWSALLLVGQDLLAEAHGGLGCM 244 AT + + P+ LP LI +A + + EGA+LDW AL L + + G G Sbjct: 185 AATREKLRLPMTPLPW----LIGIMALFSMVPEGAVLDWGALYLKDELGASVELSGFGFA 240 Query: 245 LFAIAMTAGRLGGDAVVERIGDRATLMLGTLPIMIGFLAVVAAPVAVIAMAGFLLIGLGI 304 F+ M A R GD V +R+G TL + T+ + G + AP AV+A+ GF L G+GI Sbjct: 241 AFSATMAAMRFAGDHVRDRLGATLTLRICTVTALAGMVLAGLAPNAVLAILGFALAGIGI 300 Query: 305 SNVVPVLCRRAGKQKVMPVGVAIAVITTAGYAGILMGPASIGLVAHMTGLPFAFGMLGAL 364 SN+VP+ AG + G+ ++V TT GY+G+L P+ IG +A +G F + L Sbjct: 301 SNMVPIAFSAAGNMPGLQPGIGLSVATTMGYSGMLFAPSLIGFIAEHSGFAIIFACVPVL 360 Query: 365 MCIVTL 370 +V L Sbjct: 361 FIVVLL 366 >PA3532 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 383 Score = 152 bits (383), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 119/354 (33%), Positives = 190/354 (53%), Gaps = 8/354 (2%) Query: 32 VPLAKERLAVDDRMLGLLLLCLGMGSVLAMLLTSVSNARYGSKPIIFVGGLGLALILPWL 91 +P KE+ +D+R LG LL +G+G++ A L+ R GS+ ++ G L + L+ P L Sbjct: 31 IPALKEQTQLDERALGQALLGVGVGALTAFPLSGFLVQRIGSRSVVIGGCLIMLLVFPLL 90 Query: 92 AIAGTPLALGATLFAFGVSLGAIDVAMNIYAIELERATGRPLMSGFHAHYSIGEFTGSAA 151 ++ L + GVS +DVAMNI A+++ER G+P MS H YS+G A Sbjct: 91 GLSQGWWQLALAFYVLGVSFAGMDVAMNIQAVDVERLLGKPCMSMLHGMYSLG--CLVGA 148 Query: 152 VTLFLSLQLGPLFSTLVCSMFMMIA----IVSAWPRLTATSVRQQGPVFVLPHRSVVLIA 207 ++ L P + L+ + +++ + + P + + ++G F LP R+++ + Sbjct: 149 LSAAALAGLTPFWHFLILTALGLLSLPFFVRALLPPDPSKAGARKGGGFTLPPRALLGLG 208 Query: 208 ALAAITFLVEGAMLDWSALLLVGQDLLAEAHGGLGCMLFAIAMTAGRLGGDAVVERIGDR 267 L F+ EG + DWSAL L +E LG F+ AM GRL GD + RI D Sbjct: 209 LLILCAFVSEGGVADWSALFLHSVLDASERVAALGFAAFSAAMVVGRLFGDRLRGRIDDA 268 Query: 268 ATLM-LGTLPIMIGFLAVVAAPVAVIAMAGFLLIGLGISNVVPVLCRRAGKQKVMPVGVA 326 L LG+L + G L + +P +++AGF ++GLG+S +VP++ AG Q + + Sbjct: 269 PLLRGLGSLATL-GMLVALFSPWPALSIAGFGVVGLGLSVMVPIVISAAGNQPGIDPVIG 327 Query: 327 IAVITTAGYAGILMGPASIGLVAHMTGLPFAFGMLGALMCIVTLSARMVMAEPR 380 +A ++T GY G+LMGP IGL+AH GL +A +L L ++ L A +V PR Sbjct: 328 VAAVSTVGYGGLLMGPPLIGLLAHEIGLRWALLVLVGLCLLLALRADLVRRRPR 381 >BMEI0267 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 397 Score = 142 bits (359), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 115/347 (33%), Positives = 173/347 (49%), Gaps = 12/347 (3%) Query: 16 LAFFVAGFGLAAWAPLVPLAKERLAVDDRMLGLLLLCLGMGSVLAMLLTSVSNARYGSKP 75 L F + G+ WAP +P ERL +D +GL++L G+GS+ M + +A GS Sbjct: 27 LLFLMNGYIFGGWAPKIPEFAERLGLDSAGMGLMILVCGLGSLAMMPVAGALSAHRGSGI 86 Query: 76 IIFVGGLGLALILPWLAIAGTPLALGAT--LFAFGVSLGAIDVAMNIYAIELERATGRPL 133 ++ + LA I L I P + A + FG ++ A+DV+MN A+ +E+ R + Sbjct: 87 VVRI--FALAFIPALLIITLVPNVVTAVIVMLYFGGTMAAMDVSMNANAVAVEKKMRRAI 144 Query: 134 MSGFHAHYSIGEFTGSAAVTLFLSLQLGPLFSTLVCSMFMMIAIVSAWPRLTATSVRQ-- 191 MS HA +S+G G AA FL Q G + LV + I I+ AWP + + Sbjct: 145 MSSCHAFWSLGGLIG-AATGGFLIAQFGSIVHALVTMIAATILIIVAWPSIIPDTEHHHP 203 Query: 192 --QGPVFVLPHRSVV-LIAALAAITFLVEGAMLDWSALLLVGQDLLAEAH-GGLGCMLFA 247 + LP + L+ +A + + EGA+LDW A + QDL A G G F+ Sbjct: 204 DGEKQKLALPRNPLPWLVGVMALFSMVPEGAILDWGAYHMR-QDLGASVTVAGFGFAAFS 262 Query: 248 IAMTAGRLGGDAVVERIGDRATLMLGTLPIMIGFLAVVAAPVAVIAMAGFLLIGLGISNV 307 +M R GD V +R G TL T +IG L V + A+ GF + G+GISN+ Sbjct: 263 GSMAVMRFAGDLVRDRFGAVKTLRACTAIAIIGMLIVGFGNSSATAIIGFAICGIGISNM 322 Query: 308 VPVLCRRAGKQKVMPVGVAIAVITTAGYAGILMGPASIGLVAHMTGL 354 VP+ AG + V +++ TT GY+G+L+ P+ IG VA +G Sbjct: 323 VPIAFSMAGNMPGVNPSVGLSIATTLGYSGMLVAPSLIGFVARHSGF 369