BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0155.0024.p (429 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PM1003 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenas... 439 e-123 XF1183 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenas... 391 e-108 PH0429 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenas... 272 1e-72 CAC3310 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogena... 260 3e-69 mlr3262 Non COG 222 1e-57 >PM1003 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase Pmu Pasteurella multocida Length = 424 Score = 439 bits (1128), Expect = e-123, Method: Compositional matrix adjust. Identities = 217/416 (52%), Positives = 291/416 (69%), Gaps = 7/416 (1%) Query: 6 KIAVIGLGYVGLPVAVAFARKGIPVVGFDVDASRVAELSEGFDRTREVDADDLRHGS-LT 64 KI +IGLGYVGLP+AV F +K +P VGFD++ RV L+ G D T EV ++L+H S L Sbjct: 7 KIGIIGLGYVGLPIAVEFGKK-VPTVGFDINEKRVKSLASGKDYTLEVSEEELQHASKLR 65 Query: 65 FSMDPAAIRGSDFFIVTVPTPIDDANRPDLGAMIAASRTVGSVLKKGDIIVYESTVYPGA 124 ++ + +FFIVTVPTPID +PDL +I AS T+ VLKKGD++VYESTVYPGA Sbjct: 66 YTNQTKGLEECNFFIVTVPTPIDHYKQPDLNPLIKASETIAEVLKKGDVVVYESTVYPGA 125 Query: 125 IEEECIPILAKVSDLKPGVDFAVGYSPERINPGDKLHRFETIMKVVSAQDPKTLDIVADV 184 EE C+P+L K+S LK DF VGYSPERINPGDK HR I+K+ S P + + V Sbjct: 126 TEEICVPVLEKMSGLKFNHDFFVGYSPERINPGDKEHRVTNILKITSGSTPLVANYIDFV 185 Query: 185 YGSVVTAGIHRAPSIKVAEAAKVIENTQRDLNIAFMNELSLIFQVLNIDTGDVLAAAGTK 244 Y ++ AG H+APSIKVAEAAKVIENTQRD+NIA +NEL+LIF + IDT DVL AAGTK Sbjct: 186 YKLIIKAGTHQAPSIKVAEAAKVIENTQRDVNIALINELALIFNKMGIDTEDVLNAAGTK 245 Query: 245 WNFLPFQPGLVGGHCIGVDPYYLTFRAERAGYHPEVILAGRRINDGMGQRIARECVRMLL 304 WNFLPF+PGLVGGHCIGVDPYYLT +A+ G HPE+ILA RR+ND MG+ +A + ++ ++ Sbjct: 246 WNFLPFKPGLVGGHCIGVDPYYLTHKAQSLGLHPEIILAARRLNDRMGEYVATQLIKEMV 305 Query: 305 RGKGRGGRSTVTVLGLTFKENVPDTRNSRVVDIIRELETFGIHVQVHDPLANAEDARHEY 364 + S + V+GL+FKEN PD RN++++D++ L+ + I + ++DP + +A EY Sbjct: 306 KKDIPVVNSKILVMGLSFKENCPDIRNTKIIDLVNSLKEYDIDIDIYDPWVDKYEAEAEY 365 Query: 365 GLT-LTDLDALGPADAVILAVAHDSYLAGGWPLFQRLLDGGTGLIL-DVKSKLDRN 418 GLT +T++ + DA+I+AVAH + F+ L G +L D+K LD++ Sbjct: 366 GLTPITEIHSHN-YDAIIIAVAHQQFKCMTEKDFKAL--GKENFVLYDLKYVLDQS 418 >XF1183 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase Xfa Xylella fastidiosa 9a5c Length = 433 Score = 391 bits (1005), Expect = e-108, Method: Compositional matrix adjust. Identities = 198/385 (51%), Positives = 255/385 (66%), Gaps = 2/385 (0%) Query: 6 KIAVIGLGYVGLPVAVAFARKGIPVVGFDVDASRVAELSEGFDRTREVDADDLRHG-SLT 64 +IAV+GLGYVGLP+AVAF R+ P +GFD+D RV +L G D T E++ ++L+ L Sbjct: 16 RIAVVGLGYVGLPLAVAFGRQR-PTLGFDIDICRVQQLCAGHDITCEIELEELQAARHLR 74 Query: 65 FSMDPAAIRGSDFFIVTVPTPIDDANRPDLGAMIAASRTVGSVLKKGDIIVYESTVYPGA 124 +S DP + FI+TVPTPID A +PDLG + +AS V SVLK GD+++YESTVYPG Sbjct: 75 YSSDPRELSDCQIFIITVPTPIDVAEQPDLGPLRSASMLVASVLKPGDLVIYESTVYPGT 134 Query: 125 IEEECIPILAKVSDLKPGVDFAVGYSPERINPGDKLHRFETIMKVVSAQDPKTLDIVADV 184 EE C+P+L S L VDF GYSPERINPGD+ R + I K++S P +V + Sbjct: 135 TEEVCVPLLEVGSGLCFNVDFHCGYSPERINPGDRKRRLQDICKIISGSTPDITAVVDAL 194 Query: 185 YGSVVTAGIHRAPSIKVAEAAKVIENTQRDLNIAFMNELSLIFQVLNIDTGDVLAAAGTK 244 Y ++ AG APSI+VAEAAKV+EN QRD+NIA +NEL+LIF L IDT DVL AA TK Sbjct: 195 YSQIIVAGTWCAPSIRVAEAAKVVENIQRDVNIALVNELALIFNRLGIDTLDVLEAAETK 254 Query: 245 WNFLPFQPGLVGGHCIGVDPYYLTFRAERAGYHPEVILAGRRINDGMGQRIARECVRMLL 304 WNFLPF+PGLVGGHCIGVDPYYL ++E GY+P++I RR+N + + V +L Sbjct: 255 WNFLPFRPGLVGGHCIGVDPYYLLHKSESVGYYPDLIHTARRVNSRVSWHVVDRVVALLG 314 Query: 305 RGKGRGGRSTVTVLGLTFKENVPDTRNSRVVDIIRELETFGIHVQVHDPLANAEDARHEY 364 R+ V VLG+TFKE+ PD RNSR +D++R T G V V DP A+ + A Sbjct: 315 ELSVPMTRAVVLVLGVTFKEDCPDLRNSRALDLVRMFRTLGAQVDVCDPCADPQQALEHE 374 Query: 365 GLTLTDLDALGPADAVILAVAHDSY 389 +TL G DA++LAVAH Y Sbjct: 375 AVTLCTEPKAGAYDAIVLAVAHAQY 399 >PH0429 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase Pho Pyrococcus horikoshii Length = 455 Score = 272 bits (695), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 161/391 (41%), Positives = 233/391 (59%), Gaps = 15/391 (3%) Query: 7 IAVIGLGYVGLPVAVAFARKGIPVVGFDVDASRVAELSEGFDRTREVDADDLRHGSLTFS 66 I ++GLGYVGLP+AVAF++K V+G+D++ ++ L + +V D++ L + Sbjct: 20 IGIVGLGYVGLPLAVAFSKK-FNVIGYDINTKKIDSLKKRKSYIEDVRDDEINLNRLQPT 78 Query: 67 MDPAAIRGSDFFIVTVPTPIDDANRPDLGAMIAASRTVGSVLKKGDIIVYESTVYPGAIE 126 DP ++ DF I+TVPTP+ + PDL + A+RTVG +L++G ++ EST YPG E Sbjct: 79 NDPEDLKKCDFIIITVPTPLREDKTPDLSYVKDAARTVGRILRRGQFVILESTTYPGTTE 138 Query: 127 EECIPILAKVSDLKPGVDFAVGYSPERINPGDKLHRFETIMKVVSAQDPKTLDIVADVYG 186 E IPIL + S LK DF V YSPERI+PG+K ++ E KVV P+ ++ + +YG Sbjct: 139 EVLIPILEEESGLKVIEDFGVAYSPERIDPGNKRYKIENTPKVVGGLTPEFTELASMLYG 198 Query: 187 SVVTAGIHRAPSIKVAEAAKVIENTQRDLNIAFMNELSLIFQVLNIDTGDVLAAAGTK-W 245 SV+ I K AEA K++EN R++NIA +NEL+LIF+ + ID +V+ AA TK + Sbjct: 199 SVIEK-IVPVKDCKTAEAVKMLENVFRNVNIALVNELALIFEKMGIDIWEVIEAAKTKPY 257 Query: 246 NFLPFQPGL-VGGHCIGVDPYYLTFRAERAGYHPEVILAGRRINDGM---GQRIARECVR 301 F+ F PG VGGHCI VDPYYL++RA++ G P I IN+ M +A +R Sbjct: 258 GFMAFYPGPGVGGHCIPVDPYYLSYRAKQFGIIPRFIETAGEINNYMPVHTVNLAETGLR 317 Query: 302 MLLRGKGRGGRSTVTVLGLTFKENVPDTRNSRVVDIIRELETFGIHVQVHDPLANAEDAR 361 + R K RG + V VLGL +K ++ DTR S + II EL G V+V+DP + R Sbjct: 318 KIGR-KIRGAK--VAVLGLAYKADISDTRESPAIKIIEELIERGAQVKVYDPYVKS--VR 372 Query: 362 HEYG---LTLTDLDALGPADAVILAVAHDSY 389 ++G +T T D L +D VI H + Sbjct: 373 TKFGTFRVTETLEDILKWSDCVIFVTDHSLF 403 >CAC3310 [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cac Clostridium acetobutylicum Length = 437 Score = 260 bits (665), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 147/428 (34%), Positives = 230/428 (53%), Gaps = 16/428 (3%) Query: 7 IAVIGLGYVGLPVAVAFARKGIPVVGFDVDASRVAELSEGFDRTREVDADDLRH----GS 62 + VIGLGYVGLP+AV A KG VVGFDV + +V ++ G + ++ D L+ Sbjct: 17 VGVIGLGYVGLPLAVQSAVKGYKVVGFDVQSKKVDMINNGQNYINDIPNDTLKEVVKKDK 76 Query: 63 LTFSMDPAAIRGSDFFIVTVPTPIDDANRPDLGAMIAASRTVGSVLKKGDIIVYESTVYP 122 L + + I+ +D ++ VPTP+D +PD+ + ++ VG L KG ++V EST YP Sbjct: 77 LKATFNFEFIKSTDIVLICVPTPLDKYQQPDISYVRNSTEVVGKYLNKGMLVVLESTTYP 136 Query: 123 GAIEEECIPILAKVSDLKPGVDFAVGYSPERINPGDKLHRFETIMKVVSAQDPKTLDIVA 182 G EE +P L K S LK G DF + +SPER++PG+ ++ E I KVV ++ I A Sbjct: 137 GTTEELILPTLQKESGLKCGRDFYLAFSPERVDPGNVKYKTENIPKVVGGVQKESTKIAA 196 Query: 183 DVYGSVVTAGIHRAPSIKVAEAAKVIENTQRDLNIAFMNELSLIFQVLNIDTGDVLAAAG 242 Y +++ +H S K+AE K++ENT R++NI +NE+++I +NID +V+ AA Sbjct: 197 AFYENILEVKVHEVSSPKIAEMEKILENTYRNINIGLINEMAIICNKMNIDIWEVIEAAK 256 Query: 243 TK-WNFLPFQPGL-VGGHCIGVDPYYLTFRAERAGYHPEVILAGRRINDGMGQRIARECV 300 TK + F F PG +GGHCI +DPYYLT++A YH +I IN+ M + Sbjct: 257 TKPYGFQAFYPGPGLGGHCIPLDPYYLTWKAREYNYHTRLIETSGEINNCMSMYVVERAT 316 Query: 301 RMLLRGKGRGGRSTVTVLGLTFKENVPDTRNSRVVDIIRELETFGIHVQVHDPLANAEDA 360 ++L R S + +LG+ +K+++ D R S + II E G V +DP + Sbjct: 317 KILNRFNKPLKDSKILILGIAYKKDIDDYRESPAIRIIENFELEGAKVSFYDPHISVYKY 376 Query: 361 RHE--YGLTLTDLDALGPADAVILAVAHDSYLAGGWPLFQRLLDGGTGLILDVKSKLDRN 418 +++ YG+ ++ L D VI+ H Y + + + I DV++ Sbjct: 377 KNKEHYGIDISK-SKLMDFDLVIITTDHSKYDY-------KFIQQNSNFIFDVRNATKNL 428 Query: 419 VTPAGIEL 426 + IEL Sbjct: 429 KDRSNIEL 436 >mlr3262 Non COG Length = 424 Score = 222 bits (566), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 140/394 (35%), Positives = 210/394 (53%), Gaps = 17/394 (4%) Query: 9 VIGLGYVGLPVAVAFARKGIPVVGFDVDASRVAELSEGFDRTREVD----ADDLRHGSLT 64 +IGLGYVGLP+AVA AR G PV GFD++A +V L+ G V A ++ G Sbjct: 1 MIGLGYVGLPLAVATARAGFPVSGFDIEARKVERLNNGQSYIEAVTSTALAGEVASGRFR 60 Query: 65 FSMDPAAIRGSDFFIVTVPTPIDDANRPDLGAMIAASRTVGSVLKKGDIIVYESTVYPGA 124 + D A + D I+ VPTP+ PDL + + T+ L+ G +IV EST YPG Sbjct: 61 ATADFAELTVCDVIIICVPTPLTKHREPDLSFVRNTAGTIAKHLRLGQLIVLESTTYPGT 120 Query: 125 IEEECIPILAKVSDLKPGVDFAVGYSPERINPGDKLHRFETIMKVVSAQDPKTLDIVADV 184 ++ PIL + + L+ +DF +G+SPER +PG++ TI KVV+ +V Sbjct: 121 TDDVIKPILEE-TGLQSKIDFFLGFSPEREDPGNRSFEVATIPKVVAGDGVDAATLVQAF 179 Query: 185 YGSVVTAGIHRAPSIKVAEAAKVIENTQRDLNIAFMNELSLIFQVLNIDTGDVLAAAGTK 244 Y V+ + + AEA K+ EN R +NIA +NEL ++ + ID +V+ AA TK Sbjct: 180 YQGVIETVVP-VSTTATAEAVKLTENIFRSVNIALVNELKIVLGAMGIDIWEVIEAAKTK 238 Query: 245 -WNFLPFQPGL-VGGHCIGVDPYYLTFRAERAGYHPEVILAGRRINDGMGQRIARECVRM 302 + ++PF PG +GGHC+ +DP+YLT++A I IN M + + E + Sbjct: 239 PFGYMPFYPGPGLGGHCVPIDPFYLTWKAREYELPTRFIELAAEINTAMPRHVVDELAKA 298 Query: 303 LLRGKGRG-GRSTVTVLGLTFKENVPDTRNSRVVDIIRELETFGIHVQVHDPLANAEDAR 361 L R G+ RS + ++GL +K+NVPD R S + +I +E +G + HDP Sbjct: 299 LDRRCGKALSRSRILIIGLAYKKNVPDIRESPSLRLIELIEEWGGKAEFHDPHVTEIPTT 358 Query: 362 HEY-------GLTLTDLDALGPADAVILAVAHDS 388 E+ + LT+ AL DAV++A HD+ Sbjct: 359 REHMAIKGRRSVELTEA-ALKDFDAVVVATDHDA 391