BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0152.0072.p (407 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4622 [GEPR] COG0477 Permeases of the major facilitator superfa... 363 e-100 CAP0049 [GEPR] COG0477 Permeases of the major facilitator superf... 355 1e-97 RSp1177 [GEPR] COG0477 Permeases of the major facilitator superf... 347 2e-95 mlr4214 [GEPR] COG0477 Permeases of the major facilitator superf... 325 1e-88 SMc03237 [GEPR] COG0477 Permeases of the major facilitator super... 314 3e-85 >PA4622 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 403 Score = 363 bits (932), Expect = e-100, Method: Compositional matrix adjust. Identities = 207/397 (52%), Positives = 255/397 (64%) Query: 11 DLLGHRPFLFFLSSRSLSRFSSQIGAVAIGWQIYDLTGSAFDLGMVGLVQFLPTALLVFV 70 LL HRPFL F +R + Q+ VAIGW IY+LTG+ DLG+VGLV+FLP L + Sbjct: 7 SLLRHRPFLAFWLARVCTASGFQMLTVAIGWHIYELTGNVLDLGLVGLVEFLPRVLFMLH 66 Query: 71 AGHAADRFERKRVVQACQIAEALTALFLAASTFAGTISEIQIFVATFVLGIAGAFESPAT 130 GH ADR++R+R+ CQ +AL A+ L +G I+ IFV F LG A AFE P T Sbjct: 67 TGHVADRYDRRRIAALCQAGQALVAVALVLGAASGEITRNMIFVLAFALGTARAFEMPTT 126 Query: 131 AALLPLIAPQGSLQRATAISSGAAQVATITGPALGGFAYALMPSAPYGIMMVFWLFGALL 190 ALLP + P G RA A S+ A Q ATI PALGG YA S Y ++ +L Sbjct: 127 QALLPNLVPAGLFPRAVAASASAMQAATIAAPALGGLLYAFGASWVYVPTATLYVLACVL 186 Query: 191 TGGIGRLQQAPVKNGGSSDDLFAGVTFVRSNPAILGTISLDLFAVLFGGVTALLPIYARD 250 T + Q + + D L AG+ F+RS P I G ISLDLFAVL GG TALLP++A+D Sbjct: 187 TLSLPVRNQPLTQGKATLDSLLAGIRFIRSRPDIFGAISLDLFAVLLGGATALLPVFAKD 246 Query: 251 ILQAGPLGLGILRAAPAVGALLMTMVLARHTINRRVGMRMFQAVIVFGVATVVFALSHWM 310 IL GP GLG+LR+APAVGAL M+ LA +I R VG MF +V +FG+AT+ F LS Sbjct: 247 ILLTGPWGLGLLRSAPAVGALAMSFWLAHFSIERNVGRIMFLSVGIFGLATIAFGLSKSF 306 Query: 311 WLSALALAVLGAADTISVVIRFSLVQLATPDEMRGRVGAVNFLFINASNQLGQFESGVTA 370 WLS L VLGAAD +S+VIR + VQL TPDEMRGRV AVN LFI ASNQLG+FESG+TA Sbjct: 307 WLSLGVLVVLGAADMVSMVIRGAFVQLETPDEMRGRVSAVNGLFIGASNQLGEFESGLTA 366 Query: 371 ALLGAVPSAVLGGVATVAVALLWMKLFPTLRDVEKLE 407 G VP+ VLGG+ T+ V WMKLFP+L ++L Sbjct: 367 HWFGTVPAVVLGGIGTLVVTGAWMKLFPSLAQRDRLH 403 >CAP0049 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 408 Score = 355 bits (911), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 187/386 (48%), Positives = 255/386 (66%) Query: 22 LSSRSLSRFSSQIGAVAIGWQIYDLTGSAFDLGMVGLVQFLPTALLVFVAGHAADRFERK 81 +++R S F+ Q+ VAIGWQ+Y LT SAF LG++GLVQFLP +L GH +DR++R+ Sbjct: 19 ITARVSSNFAYQMLTVAIGWQMYSLTHSAFYLGLIGLVQFLPMLVLSLFVGHISDRYDRR 78 Query: 82 RVVQACQIAEALTALFLAASTFAGTISEIQIFVATFVLGIAGAFESPATAALLPLIAPQG 141 ++V Q+ + + LA + G I++ + F + +A +FE P ALLP I + Sbjct: 79 KIVSISQLVQGICIALLAFGNYNGWITKESFLIMVFFIALAHSFEGPPMQALLPNIVERK 138 Query: 142 SLQRATAISSGAAQVATITGPALGGFAYALMPSAPYGIMMVFWLFGALLTGGIGRLQQAP 201 +A+A+ S A+Q A I GP G Y+ S Y I + ++L I ++ Sbjct: 139 IFPKASALVSSASQFAVIVGPGFAGILYSFGASLIYSITAGLLILASVLIIQIHVNKEER 198 Query: 202 VKNGGSSDDLFAGVTFVRSNPAILGTISLDLFAVLFGGVTALLPIYARDILQAGPLGLGI 261 + + FAG+TF++S P ILG ISLDLFAVLFGG TALLPIYA IL+ G GLG+ Sbjct: 199 KPDPVNLKSFFAGITFIKSRPIILGAISLDLFAVLFGGATALLPIYASSILKIGSFGLGV 258 Query: 262 LRAAPAVGALLMTMVLARHTINRRVGMRMFQAVIVFGVATVVFALSHWMWLSALALAVLG 321 LR+APAVGALLM+ +L R + R VG MF AV+ FG++T++FA+S + +S LAL VLG Sbjct: 259 LRSAPAVGALLMSALLTRKPLKRNVGKIMFTAVVCFGLSTIIFAISKSVIVSFLALFVLG 318 Query: 322 AADTISVVIRFSLVQLATPDEMRGRVGAVNFLFINASNQLGQFESGVTAALLGAVPSAVL 381 A+D ISVVIR +LVQL TPD MRGRV +VN +FI SNQLG+FESG+TA+LLG VP+A+L Sbjct: 319 ASDVISVVIRSTLVQLETPDNMRGRVSSVNMIFIGTSNQLGEFESGITASLLGTVPAALL 378 Query: 382 GGVATVAVALLWMKLFPTLRDVEKLE 407 GGV T+ V L+W KLF +L V+ E Sbjct: 379 GGVGTILVVLIWRKLFSSLFTVDSFE 404 >RSp1177 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 424 Score = 347 bits (891), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 215/410 (52%), Positives = 270/410 (65%), Gaps = 6/410 (1%) Query: 3 SATPAGARDLLGHRPFLF-----FLSSRSLSRFSSQIGAVAIGWQIYDLTGSAFDLGMVG 57 S+ PA A+ L H PF + F +R + F+ Q+ VA+GWQIYDLT SA+ LG+VG Sbjct: 8 SSPPAPAQTL-SHAPFAYPAFRLFWLARLSTTFAYQMFGVAVGWQIYDLTRSAYVLGLVG 66 Query: 58 LVQFLPTALLVFVAGHAADRFERKRVVQACQIAEALTALFLAASTFAGTISEIQIFVATF 117 L QFLP+ +LV +GH ADR++R+RVV+ CQ EAL A LAA+T G S IFV Sbjct: 67 LAQFLPSVVLVLASGHIADRYDRRRVVRICQAIEALVAAMLAAATLTGHASIQPIFVFVV 126 Query: 118 VLGIAGAFESPATAALLPLIAPQGSLQRATAISSGAAQVATITGPALGGFAYALMPSAPY 177 V+G AFE+P ALLP + P +L RA A+SS A Q I GPA+GGF Y Y Sbjct: 127 VIGAMRAFETPTLQALLPSLVPPAALPRAVALSSSAGQTGIILGPAVGGFLYVAGAPVVY 186 Query: 178 GIMMVFWLFGALLTGGIGRLQQAPVKNGGSSDDLFAGVTFVRSNPAILGTISLDLFAVLF 237 ++ +L + + APV S + LFAG+ F++ P +LG ISLDLFAVL Sbjct: 187 ATAAGLFVLAHVLVACVRTGRAAPVSRPVSLESLFAGIAFIKGRPVVLGAISLDLFAVLL 246 Query: 238 GGVTALLPIYARDILQAGPLGLGILRAAPAVGALLMTMVLARHTINRRVGMRMFQAVIVF 297 GG TALLPIYARDIL G GLG+LR+APA+GAL M + LA + R VG MF AV +F Sbjct: 247 GGATALLPIYARDILGTGAWGLGLLRSAPAIGALAMAIFLAHRPLERHVGRVMFAAVALF 306 Query: 298 GVATVVFALSHWMWLSALALAVLGAADTISVVIRFSLVQLATPDEMRGRVGAVNFLFINA 357 G+AT+VF +S W+ LS LAL VLGA D +SVVIR SLVQL TPD MRGRV AVN +F+ A Sbjct: 307 GLATMVFGVSRWLPLSMLALVVLGAGDMVSVVIRTSLVQLDTPDAMRGRVSAVNSVFVGA 366 Query: 358 SNQLGQFESGVTAALLGAVPSAVLGGVATVAVALLWMKLFPTLRDVEKLE 407 SNQLG+FESG+ A +LG VPS VLGG+ T+ V LWM+LFP L ++L Sbjct: 367 SNQLGEFESGMVAGMLGPVPSVVLGGLGTLLVVALWMRLFPALTHRDRLR 416 >mlr4214 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 412 Score = 325 bits (833), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 185/393 (47%), Positives = 243/393 (61%) Query: 15 HRPFLFFLSSRSLSRFSSQIGAVAIGWQIYDLTGSAFDLGMVGLVQFLPTALLVFVAGHA 74 H+ FL + ++R L+ F++ + +VA+GWQ+YDLT FDLG+VG+VQFLP+ LLV V G Sbjct: 17 HKAFLSYWTARFLTTFATMVVSVAVGWQMYDLTRDPFDLGIVGIVQFLPSLLLVLVTGAV 76 Query: 75 ADRFERKRVVQACQIAEALTALFLAASTFAGTISEIQIFVATFVLGIAGAFESPATAALL 134 ADRF R+ ++ + EA+ AL L A T + IF + G+A AF PA+A+L Sbjct: 77 ADRFGRRLIMALAVVVEAICALALLALTLRSISGPLPIFCVLAMFGVARAFFGPASASLF 136 Query: 135 PLIAPQGSLQRATAISSGAAQVATITGPALGGFAYALMPSAPYGIMMVFWLFGALLTGGI 194 + P A A +S A Q ATI GP GG Y + P YG V L LL I Sbjct: 137 ANLVPPEDFANAIAWNSSAWQTATIVGPVAGGLLYGVSPEVAYGTAAVLMLASGLLIFTI 196 Query: 195 GRLQQAPVKNGGSSDDLFAGVTFVRSNPAILGTISLDLFAVLFGGVTALLPIYARDILQA 254 + Q + +LF G +++ S +LG ISLDLFAVL G +ALLP+YARDILQ Sbjct: 197 PKPAQRTETEKPTLQNLFGGFSYIWSEKIVLGAISLDLFAVLLSGASALLPVYARDILQL 256 Query: 255 GPLGLGILRAAPAVGALLMTMVLARHTINRRVGMRMFQAVIVFGVATVVFALSHWMWLSA 314 GP GLG+LR+AP++GA+ + + LA H + GM M A FG TV+F LS WLS Sbjct: 257 GPWGLGLLRSAPSIGAICVAVWLAGHPMRNHAGMIMLAAAASFGAFTVLFGLSTITWLSI 316 Query: 315 LALAVLGAADTISVVIRFSLVQLATPDEMRGRVGAVNFLFINASNQLGQFESGVTAALLG 374 AL LGA D SV IR +L+QL TPDE+RGRV AVN +F+ ASN++G+F +G AAL+G Sbjct: 317 AALVFLGATDMFSVYIRETLIQLWTPDEVRGRVNAVNQVFVGASNEVGEFRAGTMAALIG 376 Query: 375 AVPSAVLGGVATVAVALLWMKLFPTLRDVEKLE 407 VP+ V+GGV +AVA LWM LFP LR V L Sbjct: 377 TVPAVVIGGVGAIAVAGLWMVLFPQLRKVRHLN 409 >SMc03237 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 415 Score = 314 bits (804), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 173/395 (43%), Positives = 242/395 (61%), Gaps = 3/395 (0%) Query: 13 LGHRPFLFFLSSRSLSRFSSQIGAVAIGWQIYDLTGSAFDLGMVGLVQFLPTALLVFVAG 72 +G+R + F SR L+ F+ QI +VA+GWQIYDLT F LG++GL QFLP+ +L+ V G Sbjct: 16 VGYRRYFF---SRLLAYFAVQIMSVAVGWQIYDLTRDPFSLGLIGLFQFLPSLVLILVTG 72 Query: 73 HAADRFERKRVVQACQIAEALTALFLAASTFAGTISEIQIFVATFVLGIAGAFESPATAA 132 ADR+ R+ ++ C + L L T G S ++ V GI AF PA+ + Sbjct: 73 SVADRYNRRAIMGICMLVSTLCGAALLLLTVTGLFSPWPVYAILVVFGIERAFLGPASQS 132 Query: 133 LLPLIAPQGSLQRATAISSGAAQVATITGPALGGFAYALMPSAPYGIMMVFWLFGALLTG 192 L P + P L A A +S + Q A I GP GG Y P+ PY + + F+ GAL+ Sbjct: 133 LAPNLVPAEDLPNAIAWNSTSWQTAMIVGPVAGGLLYGFGPTVPYAVSLGFFAAGALMVF 192 Query: 193 GIGRLQQAPVKNGGSSDDLFAGVTFVRSNPAILGTISLDLFAVLFGGVTALLPIYARDIL 252 + + + + + + AG ++++ +LG ISLDLFAVL GG AL+P++ARD+L Sbjct: 193 AVPKPARRSPPSAANWQTITAGFRYIKAEKIVLGAISLDLFAVLLGGAVALMPVFARDVL 252 Query: 253 QAGPLGLGILRAAPAVGALLMTMVLARHTINRRVGMRMFQAVIVFGVATVVFALSHWMWL 312 GP GLG+LRAAP VGA+ M + LA H I R G+ MF V +FG+ATVVF LS W+ Sbjct: 253 TLGPWGLGLLRAAPGVGAVGMAVWLAAHPIRNRAGLYMFVGVALFGLATVVFGLSATPWI 312 Query: 313 SALALAVLGAADTISVVIRFSLVQLATPDEMRGRVGAVNFLFINASNQLGQFESGVTAAL 372 S AL V+GA+D ISV +R L+ L TPDE+RGRV AVN +F+ ASN+LG+F +G+ A+ Sbjct: 313 SIAALVVMGASDMISVYVREILITLWTPDELRGRVNAVNMVFVGASNELGEFRAGMMASG 372 Query: 373 LGAVPSAVLGGVATVAVALLWMKLFPTLRDVEKLE 407 G V + V GG T+ V+LLW FP LR ++ L+ Sbjct: 373 FGTVFAVVFGGAGTLLVSLLWALGFPQLRRIDTLD 407