BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0150.0003.p (270 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value all2480 [V] COG2602 Beta-lactamase class D Nos Nostoc sp. PCC 7120 174 1e-43 BS_ybxI [V] COG2602 Beta-lactamase class D Bsu Bacillus subtilis 150 2e-36 PA5514 [V] COG2602 Beta-lactamase class D Pae Pseudomonas aerugi... 140 3e-33 slr0319 [V] COG2602 Beta-lactamase class D Syn Synechocystis 124 3e-28 Cj0299 [V] COG2602 Beta-lactamase class D Cje Campylobacter jejuni 123 3e-28 >all2480 [V] COG2602 Beta-lactamase class D Nos Nostoc sp. PCC 7120 Length = 283 Score = 174 bits (442), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 98/275 (35%), Positives = 150/275 (54%), Gaps = 14/275 (5%) Query: 3 HRRHALGLLAAATIL-PSRSFANVSYQRSEFRE----------DLRKRFFDLGTEGTFVG 51 +RR +L ++ A T L P + +N +E +L + F LG +G+ + Sbjct: 4 NRRMSLAMIVAMTTLVPFLTISNFRDMPGHSQEIQTPAIPVNVNLGRSFNQLGIKGSILI 63 Query: 52 YKIEDYLIIASDKVRSGEGKLPASTFKIPNALIALESGVVQDPDKDVFKWDGTTRSIEAW 111 Y + + R+ + LPASTFKI N+L+ALE+GV+ + D + WDG R W Sbjct: 64 YDRNNKKFYEHNAARNSQSFLPASTFKIFNSLVALETGVISN-DVAILTWDGMQRQFPTW 122 Query: 112 NRDHTLRSALAVSAFPVFQEIARRIGEEQMKKYVDIIDYGNRDIGGG--IDQFWVSGNLR 169 N+D +R A S +Q +AR+IG E+M+K++ + YGN IG ID+FW+ G L+ Sbjct: 123 NQDTNIRQAFRNSTVWFYQVLARKIGHERMEKFIKQVGYGNLQIGTPEQIDRFWLEGPLQ 182 Query: 170 IDPVQQIDFLDRLRRGVLPVGKRSQQLVCDILPVTKVGDAVIRAKTGLTDKEHGSLGWLV 229 I P QQI+FL RL R LP +R+ LV DI+ + + V+R KTG ++GW V Sbjct: 183 ITPKQQIEFLQRLHRKELPFSQRTLDLVQDIMIYERTPNYVLRGKTGWAASVTPNIGWFV 242 Query: 230 GWAEKGTDVTVFAMNMDCKTQAQIDARMSVTQQCL 264 G+ E+ +V FA N+D + AR+ VT++ L Sbjct: 243 GYLEQNNNVYFFATNIDIRNNDDAAARIEVTRRSL 277 >BS_ybxI [V] COG2602 Beta-lactamase class D Bsu Bacillus subtilis Length = 267 Score = 150 bits (380), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 82/204 (40%), Positives = 121/204 (59%), Gaps = 6/204 (2%) Query: 45 TEGTFVGYKIEDYLIIASDKVRSGEGKLPASTFKIPNALIALESGVVQDPDKDVFKWDGT 104 T+GTF+ + ++ ++ R+ + + P STFK+ NALI L+ V+D + DV +WDG Sbjct: 46 TDGTFILHDLQKDQTFVYNRKRANQRQTPQSTFKVVNALIGLQVKAVRD-EYDVKRWDGV 104 Query: 105 TRSIEAWNRDHTLRSALAVSAFPVFQEIARRIGEEQMKKYVDIIDYGNRDIGGGIDQFWV 164 R E+WNRDHTL SA+ SA +Q +AR IGEE+MK ++ + YGN DI GGIDQFW+ Sbjct: 105 KREFESWNRDHTLGSAMRESAIWYYQALARDIGEERMKTWLHTLSYGNEDISGGIDQFWL 164 Query: 165 SGNLRIDPVQQIDFLDRLRRGVLPVGKRSQQLVCDILPVTKVGDAVIRAKTG--LTDKEH 222 +L I P++Q FL++L + LP K ++V ++ + + KTG LTD Sbjct: 165 QSSLTISPLEQETFLEKLAKEELPFDKPVMKIVKRMMIQEEGDHYTLYGKTGTRLTDM-- 222 Query: 223 GSLGWLVGWAEKGTDVTVFAMNMD 246 LGW VG+ + VF N+D Sbjct: 223 -GLGWFVGFIKTEHGSYVFVTNVD 245 >PA5514 [V] COG2602 Beta-lactamase class D Pae Pseudomonas aeruginosa Length = 262 Score = 140 bits (353), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 84/243 (34%), Positives = 130/243 (53%), Gaps = 4/243 (1%) Query: 28 QRSEFRED--LRKRFFDLGTEGTFVGYKIEDYLIIASDKVRSGEGKLPASTFKIPNALIA 85 Q SE+ + + K F G +GTFV Y ++ + D+ R+ +PAST+K+ N+LI Sbjct: 17 QASEWNDSQAVDKLFGAAGVKGTFVLYDVQRQRYVGHDRERAETRFVPASTYKVANSLIG 76 Query: 86 LESGVVQDPDKDVFKWDGTTRSIEAWNRDHTLRSALAVSAFPVFQEIARRIGEEQMKKYV 145 L +G V+ D +V + G + +AW D +LR A+ S PV+QE+ARRIG E+M+ V Sbjct: 77 LSTGAVRSAD-EVLPYGGKPQRFKAWEHDMSLRDAIKASNVPVYQELARRIGLERMRANV 135 Query: 146 DIIDYGNRDIGGGIDQFWVSGNLRIDPVQQIDFLDRLRRGVLPVGKRSQQLVCDILPVTK 205 + YGN +IG +D FW+ G L+I ++Q FL RL +G LP Q V + + Sbjct: 136 SRLGYGNAEIGQVVDNFWLVGPLKISAMEQTRFLLRLAQGELPFPAPVQSTVRAMTLLES 195 Query: 206 VGDAVIRAKTGLTDKEHGSLGWLVGWAEKGTDVTVFAMNMDCK-TQAQIDARMSVTQQCL 264 + KTG LGW VGW ++ + FA+N+D +A I R+ + + L Sbjct: 196 GPGWELHGKTGWCFDCTPELGWWVGWVKRNERLYGFALNIDMPGGEADIGKRVELGKASL 255 Query: 265 TDI 267 + Sbjct: 256 KAL 258 >slr0319 [V] COG2602 Beta-lactamase class D Syn Synechocystis Length = 304 Score = 124 bits (310), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 95/263 (36%), Positives = 140/263 (53%), Gaps = 11/263 (4%) Query: 11 LAAATILPSRSFANVSYQRSEFREDLRKRFFDLGTEGTFV--GYKIEDYLIIASDKVRSG 68 ++ +T L +RS +V Q R D F +GT V + + + ++ R+ Sbjct: 43 ISNSTTLDNRSLGSVERQE---RSDWASFFDGAEAQGTIVVLDQRGGAHQLWVYNQERAD 99 Query: 69 EGKLPASTFKIPNALIALESGVVQDPDKDVFKWDGTTRSIEAWNRDHTLRSALAVSAFPV 128 PASTFKIP++L AL++GVV+D + VF+WDG R+ N+D TLRSA+ SA V Sbjct: 100 RAYSPASTFKIPHSLFALDAGVVRD-EFQVFEWDGVERNFAPHNQDQTLRSAMRNSAVWV 158 Query: 129 FQEIARRIGEEQMKKYVDIIDYGNRDIGGGIDQFWVSGNLRIDPVQQIDFLDRLRRGVLP 188 ++ A IGE + ++Y+ IDYGN D +W+ G L I +QI FL +L + LP Sbjct: 159 YEIFAAEIGEAKAREYLTQIDYGNVDSSTSKGAYWIDGALTISAQEQIHFLQKLYQNELP 218 Query: 189 VGKRSQQLVCDILPVTKVGDAVIRAKTGLTDKEHGSLGWLVGWAEKGTDVTVFAMNMDCK 248 Q+LV DI+ V + ++RAKTG G GW VGW E T FA+N+D Sbjct: 219 FRIEHQRLVKDIIIVEAGRNWILRAKTGW----EGRWGWWVGWVEWPTGPVFFALNIDTP 274 Query: 249 TQA-QIDARMSVTQQCLTDIVAL 270 + + R ++T+ L I AL Sbjct: 275 NRLDDLYKREAITRDILQSIDAL 297 >Cj0299 [V] COG2602 Beta-lactamase class D Cje Campylobacter jejuni Length = 257 Score = 123 bits (309), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 74/235 (31%), Positives = 126/235 (53%), Gaps = 7/235 (2%) Query: 36 LRKRFFDLGTEGTFVGYKIEDYLIIASDKVRSGEGKLPASTFKIPNALIALESGVVQDPD 95 L F + T GTFV Y + + ++D R+ E PASTFKI NALIAL+SGV++ Sbjct: 21 LNNWFKEYNTSGTFVFYDGKTW--ASNDFSRAMETFSPASTFKIFNALIALDSGVIKTKK 78 Query: 96 KDVFKWDGTTRSIEAWNRDHTLRSALAVSAFPVFQEIARRIGEEQMKKYVDIIDYGNRDI 155 + + + G + +W +D L SA+ S F+E+ARRIG + M++Y++ + YGN I Sbjct: 79 EIFYHYRGEKVFLSSWAQDMNLSSAIKYSNVLAFKEVARRIGIKTMQEYLNKLHYGNAKI 138 Query: 156 GGGIDQFWVSGNLRIDPVQQIDFLDRLRRGVLPVGKRSQQLVCDILPVTKVGDAVIRAKT 215 ID FW+ +L+I +Q L RL + LP + + V +++ + + + + KT Sbjct: 139 -SKIDTFWLDNSLKISAKEQAILLFRLSQNSLPFSQEAMNSVKEMIYLKNMENLELFGKT 197 Query: 216 GLTDKEHGSLGWLVG--WAEKGTDVTVFAMNMDCKTQAQIDARMSVTQQCLTDIV 268 G D++ + W+VG + + FA+N+D + R + ++ L ++V Sbjct: 198 GFNDEQ--KIAWIVGFVYLKDENKYKAFALNLDIDKFEDLYKREKILEKYLDELV 250