BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0146.0061.p (308 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll8218 [GER] COG0697 Permeases of the drug/metabolite transport... 99 1e-20 AGc3255 [GER] COG0697 Permeases of the drug/metabolite transport... 96 8e-20 PA4287 [GER] COG0697 Permeases of the drug/metabolite transporte... 93 8e-19 AGpA485 [GER] COG0697 Permeases of the drug/metabolite transport... 79 1e-14 mlr8275 [GER] COG0697 Permeases of the drug/metabolite transport... 73 6e-13 >mll8218 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 319 Score = 99.0 bits (245), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 91/306 (29%), Positives = 149/306 (48%), Gaps = 7/306 (2%) Query: 1 MDAEPPKAQVSRPAKGWEDAVALTGF---ILVAVGQASNQVLARGLAGSVPPFSLAFFRW 57 M A P Q ++P G +LTG+ IL + A + A+ +A +PP+ L F+R Sbjct: 1 MQAIPIAHQAAQPVVG--PISSLTGYPAAILCWLLSAGVYIAAKWVAPEMPPWGLCFWRL 58 Query: 58 SIIAIGLAPFAIAAIRGGKIPLAQNL-WPILAAGFLGMFLCGGPVYIAGITTTAIHIALI 116 ++ L P + G I L + ++A G +G+ LC G +Y T A +I Sbjct: 59 TLACAILLPI-VHRHHGAMIGLLRTRAVEVVAVGAIGLTLCQGMIYHGLNDTNATTAGII 117 Query: 117 FALSPIMVLLISAALGIEHIGPLQWLGTALALGGALLIVSGGHLETLTQSSAAWGDLLVV 176 ALSP+M ++++ + E +G + LG +AL G + IV+ G+L L Q G+L +V Sbjct: 118 MALSPVMTMVLARFVLGEPLGLWKSLGALVALAGMIFIVAHGNLTALLQLEFNAGELWIV 177 Query: 177 CAMLGWSGYTLLQSRVAPRASLLARVSLFSAAGALCSLPPALHEMWATPAEVFNTRAFEA 236 + W YT+L R LL V L AGAL +LP L E++ V N + A Sbjct: 178 GSAFCWGLYTVLLRRAKFGIELLPMVVLLLGAGALVALPFHLWELFNDERSVMNVHSILA 237 Query: 237 YVFAGLVPGLIAYAGFAWLGARFGSVRSSLVLYVAPIASALLSWIILGEPPKLIHLVGGL 296 + G + Y + G+ R+S++LY+ + A+L++++LGE L+G Sbjct: 238 LAYLAGPGGALMYYLYNKSVETLGASRASMLLYLQTVFVAMLAYLLLGEDLHDYDLIGAA 297 Query: 297 LILGGV 302 I+ G+ Sbjct: 298 FIVAGI 303 >AGc3255 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 306 Score = 96.3 bits (238), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 91/307 (29%), Positives = 133/307 (43%), Gaps = 29/307 (9%) Query: 11 SRPAKGWEDAVALTGFILVAVGQASNQVLARGLAGSVPPFSLAFFRWSIIAIGLAPFAIA 70 ++PA F+ V +SN + RG+ G V PF AF RW + +APF IA Sbjct: 3 NKPASQQTRLTDWLIFLAVPFFFSSNVIFGRGVVGEVSPFIAAFIRWMGSTLIIAPFMIA 62 Query: 71 AIRGGKIPLAQNLWPILAAGFLGMFLCGGPVYIAGITTTAIHIALIFALSPIMVLLISAA 130 R + + L G LGM +CGG VY TTA + LI+ S + ++L Sbjct: 63 DWRNCLAFVRDKMLLWLVLGILGMGICGGVVYWGLTMTTAANGTLIYTTSSLFIILFQRI 122 Query: 131 LGIEHIGPLQWLGTALALGGALLIVSGGHLETLTQSSAAWGDLLVVCAMLGWSGYTLLQS 190 I L+ G +A G IV G + L + GD ++ A + ++ Y+LL Sbjct: 123 FQGRPIRKLEVAGMVIAFAGVAAIVLKGDISALRHMNFNIGDFAILTAAIAFAIYSLLLR 182 Query: 191 RVAPRASLLARVSLF---SAAGALCSLPPALHEM------------WATPAEVFNTRAFE 235 P A +A SLF + +GAL LPPA E+ WA + Sbjct: 183 D--PAARQMASFSLFGLIAFSGALVLLPPAALELAQGGMLPATGAAWAKIGGII------ 234 Query: 236 AYVFAGLVPGLIAYAGFAWLGARFGSVRSSLVLYVAPIASALLSWIILGEPPKLIHLVGG 295 L L+A+ F FG + + LY+ P S L++ I LGE + H +G Sbjct: 235 ------LFASLLAFYCFTHTVRVFGPATAGITLYMMPPVSILMATIFLGETFETYHAIGI 288 Query: 296 LLILGGV 302 +L+ GGV Sbjct: 289 VLVTGGV 295 >PA4287 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 296 Score = 92.8 bits (229), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 73/271 (26%), Positives = 132/271 (48%), Gaps = 8/271 (2%) Query: 34 ASNQVLARGLAGSVPPFSLAFFRWSIIAIGLAPFAIAAIRGGKIPLAQNLWPILAAGFLG 93 A N V+ + G + P + FFRW ++ + L PF + + + + NL + G LG Sbjct: 14 AGNTVVNKLAVGIIQPAEIGFFRWLLVGLALTPFMLGPVLRNRRYILANLGKFVVLGLLG 73 Query: 94 MFLCGGPVYIAGITTTAIHIALIFALSPIMVLLISAALGIEHIGPLQWLGTALALGGALL 153 M + Y A T+A ++ +I +L P+M L +++++ + LG ++L G +L Sbjct: 74 MAVYQSLAYYAAALTSATNMGIILSLMPLMSLGLASSILAHRLNAGALLGALVSLAGVVL 133 Query: 154 IVSGGHLETLTQSSAAWGDLLVVCAMLGWSGYTLLQSRVAPRASLLARVSLFSAAGALCS 213 ++S GHL L + GD +++ A L ++ Y++L + + + + + L L + Sbjct: 134 VISQGHLGALLEHGVNLGDAMMIVATLAYAVYSVLLKKWSLKLPAMQLLYL----QVLVA 189 Query: 214 LPPALHEMWATPAEVFNTRAFEAYVFAGLVPGLIAYAGFAWLG--ARFGSVRSSLVLYVA 271 + L +P N ++A L ++ A AW+ AR G R +L + Sbjct: 190 ILALLPLYLLSPRTGLNAANLPLVLYAALFASIV--AALAWMHGVARLGPSRMALFFNLL 247 Query: 272 PIASALLSWIILGEPPKLIHLVGGLLILGGV 302 PI +A ++ ++LGE + HLVGG L L GV Sbjct: 248 PIITACIATLVLGERLTVHHLVGGALTLAGV 278 >AGpA485 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 309 Score = 79.0 bits (193), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 79/276 (28%), Positives = 137/276 (49%), Gaps = 10/276 (3%) Query: 36 NQVLARGLAGSVPPFSLAFFRWSIIAIGLAPFAIAAIRGGKIPLAQNLWPILAAGFLGMF 95 N ++++ AG++ P ++AF RW I + L P + +A +L ++ G LGM Sbjct: 25 NTIVSKLAAGAIAPGTIAFERWFIAFVILTPLVYRDAWRHRRTIAAHLPKLILLGLLGMA 84 Query: 96 LCGGPVYIAGITTTAIHIALIFALSPIMVLLISAALGIEHIGPLQWLGTALALGGALLIV 155 C G Y A TTA ++A++ +L P++ L++SA E L +G ++L G +++ Sbjct: 85 ACQGLGYYAAGLTTATNMAIMLSLVPLLTLILSAVFLAERPSSLAVIGGIISLSGIFIVL 144 Query: 156 SGGHLETLTQSSAAWGDLLVVCAMLGWSGYTLLQSRVA-PRASLLARVSLFSAAGALCSL 214 G L GD +++ A+L ++GY +L R A P A+ S++ GA L Sbjct: 145 GQGDPSRLLSQGVGRGDAMMLAAVLAYAGYGILLRRWAIPLATW---TSIYVQIGAAVVL 201 Query: 215 PPALHEMWATPAEVFNTRAFEAYVFAGLVPGLIAYAGFAWLGA--RFGSVRSSLVLYVAP 272 + + A A A Y +PG I A F W+ A G+ R+++ + + P Sbjct: 202 LVPSYLLSAPSALTLPNTAMVLY---AAIPGSI-LAPFVWMTAVKHLGAARTAIFMNLIP 257 Query: 273 IASALLSWIILGEPPKLIHLVGGLLILGGVWASLRK 308 I +A+++ I LGE + HL+GG + + G+ RK Sbjct: 258 IFTAIVAAIFLGEALYIYHLLGGGMTVAGIILVQRK 293 >mlr8275 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 297 Score = 73.2 bits (178), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 89/288 (30%), Positives = 131/288 (45%), Gaps = 16/288 (5%) Query: 19 DAVALTGFILVAVGQASNQVLARGLAGSVPPFSLAFFRWSIIAIGLAPFAIAAIRGGKIP 78 D A L VG AS R + P L R++I A+ A F A++ +P Sbjct: 15 DTTAAIAVALTVVGWASAFPAIRAGLAAFGPLELGALRFAIAAVPAAIFL--AVKRPALP 72 Query: 79 LAQNLWPILAAGFLGMFLCGGPVYIAGITTTAIHIALIFALSPIMVLLISAALGIEHIGP 138 +W ++ G + + L + +T +A I +SPI +++ AL E Sbjct: 73 RLDEVWRLVFGGAIFVALYTAMLNFGELTVSAGAAGFIINVSPIFTAIMAMALLGERFSR 132 Query: 139 LQWLGTALALGGALLIV----SGGHLETLTQSSAAWGDLLVVCAMLGWSGYTLLQSRVAP 194 W GTA++ G +I G H G LLV+ + L + T++Q + Sbjct: 133 WAWAGTAISFAGIGVIAMADGQGLHFNA--------GALLVLGSALCSAVNTIVQKPLFA 184 Query: 195 RASLLARVSLFSAAGALCSLPPALHEMWATPAEVFNTRAFEAYVFAGLVPGLIAYAGFAW 254 R L + GALC L P L +A A V NT A +F G+VP LIAYA +A Sbjct: 185 RHHPLTISASNMVLGALC-LSPFLPSGFAQ-AAVANTAGLGAVIFLGIVPSLIAYAAWAT 242 Query: 255 LGARFGSVRSSLVLYVAPIASALLSWIILGEPPKLIHLVGGLLILGGV 302 +R + R+S LY+ SAL+ + LGE P L+ ++GG L LGGV Sbjct: 243 ALSRLPAARASNFLYLVSPMSALIGFFWLGEVPTLLGILGGALALGGV 290