BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0144.0034.p (1232 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc01910 Non COG 585 e-166 MA2362 [S] COG4717 Uncharacterized conserved protein Mac Methano... 75 9e-13 BS_yhaN [S] COG4717 Uncharacterized conserved protein Bsu Bacill... 64 3e-09 >SMc01910 Non COG Length = 1153 Score = 585 bits (1509), Expect = e-166, Method: Compositional matrix adjust. Identities = 446/1166 (38%), Positives = 600/1166 (51%), Gaps = 27/1166 (2%) Query: 1 MRIRKLGLRRYGKFTDAFIDFGERVAGCADLHIVYGPNEAGKSTAMSACTDLIFGIPAQS 60 MR+++L L RYGKFT+ +DFGE G D H++YGPNEAGKST S DLIFGI S Sbjct: 1 MRLQRLELVRYGKFTERHLDFGEAKLGEPDFHLIYGPNEAGKSTLFSGFLDLIFGIERSS 60 Query: 61 RFNFLHPYAAMRIEAEVETSGWIRRFCRIKRPHNSLLDDADNPVPDTLLPGELGGIDRGA 120 + FLHPY AMRI V + RIKR NSL+ + P+PD L LG IDR Sbjct: 61 PYGFLHPYQAMRIGGIVAAGNRLHHAYRIKRNANSLIGPDEQPLPDGLFSTALGSIDRAT 120 Query: 121 YHTMFCLDDETLEAGGESILASKGDLGHLLFSATAGLADLSTRLGSVQAEAEAFFRPGKR 180 Y TMF LDD+++E GGE+IL S+G+LG LLFSA++GL D + L ++AEA++FFRP R Sbjct: 121 YSTMFSLDDDSIEEGGEAILKSEGELGSLLFSASSGLPDSTAVLAVLRAEADSFFRPQAR 180 Query: 181 SGGLLELKKNLAALNEERERIDTLASEYARLVIQRDDAAAAYAEAIAQRSRTQARMDQVQ 240 L ELK L AL ER ID A EYA L A + A RS +A D+++ Sbjct: 181 KHQLAELKAELDALKAERNEIDVNAREYAALRKALASMRARHEAAARLRSELRADRDRMR 240 Query: 241 SFINALPRLRSLRALRTELSPLARLRVAPSSWGRDLPALTSRQAALAAQMRSATETIVAL 300 + +A+P L LR R EL+ L V P+ W +LP L R A +AA +R E + Sbjct: 241 AQRDAVPLLARLRGARQELAGRDPLPVPPAEWQEELPVLRRRDAEIAAGLRQLHEELTRR 300 Query: 301 QRELEGLVVNASACALNSRMELL--TDLRARYVTAAKDLPDRRLALGLAEQKIGHVLTLL 358 + EL L + A A+ R L T L ARY+TA +D+P R L +I L L Sbjct: 301 REELAALPRDEQALAIAERFGALRETALEARYLTADRDMPARLEELAKTAAEIDACLVRL 360 Query: 359 DRGAEQEPARLLLSTGVTGTLRDLMERRSGVEAALASSEAELAKAEGALADAEARVCEHA 418 + A LLL L+DL+ R + + LAS+ E AEG DAE V Sbjct: 361 GEADNPDLASLLLPAARAVRLQDLVRRHASLSERLASAREETETAEGNHGDAEREVARLK 420 Query: 419 TGLDEATTAILTATIESARQSDDVAR----LREADRMRRERADEFADRLRELFPWTGGRD 474 G A A L + RQSD + R RE DR+ DRL EL P+ G D Sbjct: 421 EG--AADPAFLAERVHLLRQSDCLLRQQSSAREIDRLE----AAICDRLDELRPFAGTID 474 Query: 475 DLFAVMVPAPDQLQRWASAETQLSREIDTRQVEFDRIDTEAKRL---EAKIAVLGAATAV 531 DL A+ PAP ++ W + + E + R DRI E++R EA++A + A V Sbjct: 475 DLAALPAPAPAVVEAWRAEDHA---EAERRLRLADRIADESERQAGDEARLAAIAANGGV 531 Query: 532 VSDQETAEAWSAREAAWAAHKKALDARTAAEFETAMRKLDLITEQRSRHASAIADLNRAL 591 V D E R+ AW H+ L +TA FETA+ + D IT R A +A++ Sbjct: 532 VDDAAVCELRRRRDTAWQRHRAGLGEQTAIAFETALNEHDAITALRLAQAERVAEIRSLT 591 Query: 592 LDSADVHARREQVQQHLEEGLARRATLIMGVEKALRAIGNGLDHTVSLSGLNLWLQKLDR 651 L + AR + + + +R L + RA G L L L WL Sbjct: 592 LAVTERRARLQSLDAQRKAAEEQRQRLSAEIGTTARACG--LPCITGLPQLEAWLAARAS 649 Query: 652 AIGAEGKLAAAEREW-QLMRDAAASSCERLAETLRRSGVELPRSDDLGAMLSAGQ----A 706 A+ G+L A +E + + + A+ C AE L R G+ + L A+L+ + Sbjct: 650 ALELRGELRTALKERDRAVAEEKAAVCSLRAE-LARLGITDALPERLDALLAVAELVSSR 708 Query: 707 ALDRAAGAKNLRAALEDRKRDLNFRETQLEGARLADRSWREAWQDACAACWLGERGRAST 766 A +A +N A + L R T A A SW W +A A WL + Sbjct: 709 AEAASAAYRNAVAQFQRASEALEKRRTVFAAAEAAMASWCGEWDEALAGTWLSRQVERPQ 768 Query: 767 TAVVRETLEALAELASALERRAELADRIAKMQRDQTQFEAEVEALAGAIGLARGRSDVLA 826 + L L +L ++++AEL R+A M+RDQ F V LA +G A+ DVL Sbjct: 769 QQEIGPVLAVLQDLDKLMQKKAELDHRVAGMRRDQAAFTESVVGLAAVLGEAQA-GDVLT 827 Query: 827 LCEEVVNSVASATKALDRRQELEERLGTEQNKTRSLANDVAEMQSRADLMMKHFEVGALA 886 L V + VA+A + +RR L+ + + SL + + ++ F+ G L Sbjct: 828 LFCAVRDRVAAALQKEERRLALQGNIERMEESLDSLRAEERLHAANRRRVLDFFDCGTLD 887 Query: 887 EVEGCLRSLDRRSDLQTRLEQTQREIVEVMKVETIEQAEDALDALQQGSLESELIELKAR 946 E CL + L+ R + + ++ + V T +AE L L L EL L+ Sbjct: 888 EAAACLEAAREEQRLRQRCSEMESDLAARLGVATAAEAEALLADLDDRELGLELARLEEA 947 Query: 947 FEDEDGRTRDRFAALDRAEAGIAGVGGDAAVAVLESKRRTILLTIEEQALEYLKLKLGMA 1006 + D + A + E +A V G VA +E +RRT+LL IE +A+ YL+L+ G+ Sbjct: 948 IDAADRDVGELHADVRTRERALAAVEGGDRVAEVEQRRRTLLLDIESKAIGYLRLRAGVI 1007 Query: 1007 GAERALRAYREHHRSSMMARASGAFALISRGAYSGLATQPSNGSELLIAKGSDGGSKLAS 1066 AE+ALR +RE HRS+MM RAS F IS G YSGL+TQ G E LIA + GGSKLA Sbjct: 1008 AAEQALRLFRERHRSAMMQRASRTFMHISGGEYSGLSTQADKGQEFLIANTAAGGSKLAR 1067 Query: 1067 ELSKGTRFQLYLALRVAGYHEIAQVRSPAPFLADDIMETFDDFRAEEAFRLLAAMARRGQ 1126 +LSKGTRFQLYLALR+AGYHE+A R PF+ADDIMETFDD RA AF L+A MA GQ Sbjct: 1068 DLSKGTRFQLYLALRIAGYHEVAATRETLPFIADDIMETFDDGRAGRAFELMAEMADVGQ 1127 Query: 1127 VVYFTHHRHLCEIAKVVEPSVKIHVL 1152 V+Y THH HLC+IA+ P V IH L Sbjct: 1128 VIYLTHHEHLCDIARSACPGVTIHRL 1153 >MA2362 [S] COG4717 Uncharacterized conserved protein Mac Methanosarcina acetivorans str.C2A Length = 1300 Score = 75.1 bits (183), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 109/442 (24%), Positives = 185/442 (41%), Gaps = 44/442 (9%) Query: 720 ALEDRKRDLNFRETQLEGARLADRSWREAWQDACAACWLGERGRASTTAVVRETLEALAE 779 LE L ++ LE L +R+ R+A + + WLG G + +V LE + Sbjct: 865 TLELESESLEHKKEDLEARLLEERTQRDALSEKWTS-WLGTYGLDPSLSV-ESVLEIFSI 922 Query: 780 LASALERRAELADRIAKMQRDQTQFEAEVEALAGAIGLARGRSDVLALCEEVVNSVASAT 839 + +R+ + + + +T EA +AG VL CE + ++ T Sbjct: 923 IGRCFDRQRAIRNLEELIASGKTSIEAYEAKVAG----------VLQECERPFSGLSFDT 972 Query: 840 KALDRRQELEERL----GTEQNKTRSLANDVAEMQSR----------ADLMMKHFEVGAL 885 + R +LEE +Q KTRS ++ +R ADL+ E G+ Sbjct: 973 QVEKLRSDLEEASEEARSLQQLKTRSKELEIELQAAREKSEAAEKELADLL----ESGSA 1028 Query: 886 A---EVEGCLRSLDRRSDLQTRLEQTQREIVEV----MKVETIEQAEDALDALQQGSLES 938 A E R +R++L+ R+ + +++I V K E + A D L Sbjct: 1029 ATEDEFRENARHWAQRTELENRVREAEQQIRRVSGDGKKYELFVEELQASDPLGLEEENR 1088 Query: 939 ELIELKARFEDEDGRTRDRFAAL-DRAEAGIAGVGGDAAVAVLESKRRTILLTIEEQALE 997 +L E E E DR A+ ++ E G G A + ES +L + E++ + Sbjct: 1089 KLEECLETLEQETSENLDRRGAIGNQIEQLEHGSEGSLARVMQES----LLEDLHEKSRK 1144 Query: 998 YLKLKLGMAGAERALRAYREHHRSSMMARASGAFALISRGAYSGLATQPSNGSELLIAKG 1057 + L L +A+ Y + + +++ A F I+ G Y+ + + P N SE+ + + Sbjct: 1145 WASLVLARKVLAKAIEVYEKERQPAVIVEAQTFFTKITAGRYTRIYS-PLNSSEIYV-ED 1202 Query: 1058 SDGGSKLASELSKGTRFQLYLALRVAGYHEIAQVRSPAPFLADDIMETFDDFRAEEAFRL 1117 +G K ELS+GT QLYL+LR E + P + DD++ FD R + Sbjct: 1203 REGRQKTVQELSRGTAEQLYLSLRFGFIREFGRHSESLPIVFDDVLVNFDPERCKSTCEA 1262 Query: 1118 LAAMARRGQVVYFTHHRHLCEI 1139 + + Q+ YFT H E+ Sbjct: 1263 IKDLVPGNQLFYFTCHPETVEM 1284 >BS_yhaN [S] COG4717 Uncharacterized conserved protein Bsu Bacillus subtilis Length = 963 Score = 63.5 bits (153), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 62/251 (24%), Positives = 104/251 (41%), Gaps = 49/251 (19%) Query: 1 MRIRKLGLRRYGKFTDAFIDFGERVAGCADLHIVYGPNEAGKSTAMSACTDLIFGIPAQS 60 +RI L + +YGKF++ DF + + ++YG NEAGK+T MS ++FG P Sbjct: 4 LRIISLHIYQYGKFSNRTFDFS-----ASPVQVIYGLNEAGKTTMMSFIESMLFGFPKTK 58 Query: 61 RFNFL------------HP-YAAMRIEAEVETSGWIRRFCRIKRPHNSLLDDADNPVPDT 107 ++ HP Y ++IE T G + S+ + Sbjct: 59 KYEPKTGGVYGGVLEAEHPEYGVLKIE---RTKGTAEKL--------SVYTEKGEVKQGD 107 Query: 108 LLPGELGGIDRGAYHTMFCLDDETLEAGGESILASKGD-LG-HLLFSATAGLADLSTRLG 165 +L G DR Y ++ D G + I A D +G LLFS+ G +S Sbjct: 108 VLKQLFQGTDRSLYKAIYSFDV----FGLQEIHAFNRDKIGEFLLFSSLFGAEAVSKLDS 163 Query: 166 SVQAEAEAFFRPGKRSGGLLELKKNLAALNEERERIDTLASEYARLVIQRDDAAAAYAEA 225 + E+E ++P R+ LN+E E + LA + + Q + A Y + Sbjct: 164 RLTKESERLYKPNGRN----------PQLNQELETLKQLAVK----LKQAEAEEAGYHQL 209 Query: 226 IAQRSRTQARM 236 + ++ +AR+ Sbjct: 210 LEEKRTLEARL 220