BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0144.0033.p (425 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc01909 [L] COG0420 DNA repair exonuclease Sme Sinorhizobium me... 427 e-119 MA2363 [L] COG0420 DNA repair exonuclease Mac Methanosarcina ace... 207 3e-53 lin2325 [L] COG0420 DNA repair exonuclease Lin Listeria innocua 174 5e-43 BS_yhaO [L] COG0420 DNA repair exonuclease Bsu Bacillus subtilis 168 2e-41 SA1662 [L] COG0420 DNA repair exonuclease Sau Staphylococcus aur... 140 7e-33 >SMc01909 [L] COG0420 DNA repair exonuclease Sme Sinorhizobium meliloti Length = 430 Score = 427 bits (1097), Expect = e-119, Method: Compositional matrix adjust. Identities = 211/413 (51%), Positives = 276/413 (66%) Query: 4 YRFVHAADIHLDSPLRSLALRDPELADFISNASRQVFARIIDLCLEERVQALLLAGDLYD 63 +RFVH AD+HLDSPLRSLALR+ ELA + +A+R RI+DLC+ E V ALL+AGDLYD Sbjct: 8 FRFVHTADLHLDSPLRSLALRNAELAGLVRSATRNALVRIVDLCIAESVDALLIAGDLYD 67 Query: 64 GDQTSMKTARFLGEQLRRLDAAGIRTFIIRGNHDALARITKELVFPPNVHLFGGRAEAIE 123 G QTSM TA FL +LRRLD AGIRTFIIRGNHD+ +++T+EL PP+VH+F GR+ A+ Sbjct: 68 GSQTSMNTALFLAGELRRLDEAGIRTFIIRGNHDSQSQVTRELTLPPSVHVFAGRSRAVH 127 Query: 124 VERDRGERSIVLHGLSFAKPHAPEGLLAKYRPPVQDATNIGMMHTSLGGSPSHDVYAPCS 183 V+ R++ +HG+SFA PHAPE LL ++ PPV NIGM+HTSL GS +HD YAPCS Sbjct: 128 VKTLANGRTVHVHGVSFADPHAPESLLPQFHPPVAGGINIGMLHTSLSGSAAHDPYAPCS 187 Query: 184 TSDLLGSGFRYWALGHIHKRSTIEGSCAIVMPGIPQGRDIGESGPKSVTLASVLDDGSIA 243 ++L GF YWALGH+H+R IVMPG+PQGRDI E+G K VT+ ++ D+G + Sbjct: 188 VAELQRHGFDYWALGHVHQRQVHCEKPFIVMPGMPQGRDINEAGTKGVTVVTIDDEGLVT 247 Query: 244 LEERIVSLAQFERVGLDASGTATWHDLVARLETSLQDAATRSVSDHLVVRLAISGTTPLA 303 L+ER A FER +D SG A W D++ + + L +D+L++RL ++G TPLA Sbjct: 248 LDERPTGTAAFERHEIDVSGIADWRDMLDAVTSELILLRKNMAADNLILRLTLTGATPLA 307 Query: 304 WNMRRDADLLRTEAETRAKSLGDVWIEKLEIDCRRTPAGATASTDQLDALRTTMNGEVVG 363 W +RRDADLL E A +G WIE E+ C+ T + D + L + +V+ Sbjct: 308 WRLRRDADLLEAEIVNIAAGIGGCWIENTEMSCQATGNAEQNAADPVGELAALVENDVLP 367 Query: 364 SEGFRTEAMDTVKELLAQLPPECRRAIAPDEAALEDLVVRLAGEGAEEVLARL 416 S GFR E KELL QLPPE R+ +A DE ALE L + A G+ +VLA L Sbjct: 368 SFGFRAELSGVAKELLQQLPPELRQVLAGDEEALERLALEAALAGSADVLAHL 420 >MA2363 [L] COG0420 DNA repair exonuclease Mac Methanosarcina acetivorans str.C2A Length = 443 Score = 207 bits (528), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 123/336 (36%), Positives = 187/336 (55%), Gaps = 11/336 (3%) Query: 6 FVHAADIHLDSPLRSLALRDPELADFISNASRQVFARIIDLCLEERVQALLLAGDLYD-G 64 FVHAAD+HLDSP ++ D EL + ++ A+ Q + II+LC+EE V LL+AGD+YD Sbjct: 24 FVHAADLHLDSPFVGISGIDQELGERLAKATFQAYEAIIELCMEEEVDFLLIAGDVYDSA 83 Query: 65 DQTSMKTARFLGEQLRRLDAAGIRTFIIRGNHDALARITKELVFPPNVH-LFGGRAEAIE 123 D+ RF+ E LR+L+ AGI+ FI GNHD L + L +P NVH + G +AE +E Sbjct: 84 DKNLYAQVRFI-EGLRKLETAGIQIFICHGNHDPLDGWSASLKWPANVHTMRGDKAEVVE 142 Query: 124 VERDRGERSIVLHGLSFAKPHAPEGLLAKYRPPVQD--ATNIGMMHTSLGGSPSHDVYAP 181 +++ GE + + G+S+ H + L+ + P +D IG++H S+G P HD YAP Sbjct: 143 FKKE-GETAAFVVGMSYPTRHIMKNLVQDF-PKKEDHWPFTIGLLHCSVGSYPEHDPYAP 200 Query: 182 CSTSDLLGSGFRYWALGHIHKRSTI-EGSCAIVMPGIPQGRDIGESGPKSVTLASVLDDG 240 C+ DL G+ YWALGHIH S + + + ++ PG PQGR GE+G + L +V G Sbjct: 201 CTLQDLREPGYDYWALGHIHTPSVVCKEAPVVIYPGNPQGRHPGETGARGCCLVNVSSGG 260 Query: 241 SIALEERIVSLAQFERVGLDASGTATWHDLVARLETSLQDAATRSVSDHLVVRLAISGTT 300 +I+ + ++ + G +LV L++ L + S + RL +SG Sbjct: 261 AISTKFVETDSVRWHIREISIEGLEKEGELVENLQSQLDEIRENSGGRSAICRLVLSGRG 320 Query: 301 PLAWNMRRDA---DLLRTEAETRAKSLGDVWIEKLE 333 PL +R + DLL T E +S W+E++E Sbjct: 321 PLHLTLREEGFLEDLLHTLREDEIRSRQFTWVERIE 356 >lin2325 [L] COG0420 DNA repair exonuclease Lin Listeria innocua Length = 411 Score = 174 bits (440), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 106/347 (30%), Positives = 178/347 (51%), Gaps = 27/347 (7%) Query: 1 MTAYRFVHAADIHLDSPLRSLALRDPELADFISNASRQVFARIIDLCLEERVQALLLAGD 60 M +F+H AD+HLDSP L+ L + ++ Q RII + ++E V+ +L+AGD Sbjct: 1 MKEIKFLHIADLHLDSPFIGLSTLPQPLFSAVQESTFQSLERIITIAIKEAVEFVLIAGD 60 Query: 61 LYDGDQTSMKTARFLGEQLRRLDAAGIRTFIIRGNHDALARITKELVFPPNVHLFGGRAE 120 +YD + S++ ++++RL+ AGI+ FII GNHD + + ++L P NVH+F + E Sbjct: 61 IYDSEDQSVRAQARFSKEMKRLEQAGIKAFIIHGNHDFIEKHKEKLQLPGNVHVFSEQVE 120 Query: 121 AIEVERDRGERSIV-LHGLSFAKPHAPEGLLAKYRPPVQDATNIGMMHTS-LGGSPSHDV 178 +E G +IV ++G S+ + H + +Y + +IG++H S L S HDV Sbjct: 121 MAAMETKNG--AIVHIYGFSYGERHIRASRVNEYNKQGEADFHIGLLHGSELSSSEDHDV 178 Query: 179 YAPCSTSDLLGSGFRYWALGHIHKRSTIEGSCAIVMPGIPQGRDIGESGPKSVTLASV-- 236 YAP ++ GF YWALGHIHKR + S ++ PG QGR+ ESG K ++ ++ Sbjct: 179 YAPFRIQEITKKGFDYWALGHIHKRQLLAESPSVYYPGNIQGRNRKESGEKGASIVTLSA 238 Query: 237 -------LDDGSIALEERIVSLAQFERVGLDASGTATWHDLVARLETSLQDAATRSVSDH 289 + I EE I++L + S T++ + +L + Q + S H Sbjct: 239 SNTTIDFIATSPIIWEEVIITLP-------ENSEINTFYREITKLLATYQ-GQSNSFFLH 290 Query: 290 LVVRLAISGTTPLAWNMRRDADLLRTEAETRAKSLGDVWIEKLEIDC 336 ++V++A N +L+ E + + +W+ KL I+ Sbjct: 291 VIVQMA----NKQKINTTDWLQMLQEETDLTGSTF--IWVHKLTIEL 331 >BS_yhaO [L] COG0420 DNA repair exonuclease Bsu Bacillus subtilis Length = 408 Score = 168 bits (426), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 104/303 (34%), Positives = 149/303 (49%), Gaps = 6/303 (1%) Query: 1 MTAYRFVHAADIHLDSPLRSLA-LRDPELADFISNASRQVFARIIDLCLEERVQALLLAG 59 +T F+HAAD+HLDSP ++ L +P A I ++ +ID + E V +LLAG Sbjct: 2 LTDLTFIHAADLHLDSPFYGISHLPEPIFAR-IKESTFASVRHMIDAAVREHVDFILLAG 60 Query: 60 DLYDGDQTSMKTARFLGEQLRRLDAAGIRTFIIRGNHDALARITKELVFPPNVHLFGGRA 119 DL+D S+K FL +Q RL GI ++I GNHD L + +P NVH+F Sbjct: 61 DLFDEANRSLKAQLFLKKQFERLRECGISVYVIFGNHDHLGGEWTPIEWPENVHIFSSAV 120 Query: 120 EAIEVERDRGERSIVLHGLSFAKPHAPEGLLAKYRPPVQDATNIGMMHTSLGGSPSHDVY 179 + G R ++G S+ E A+YR +IGM+H +L GS HD Y Sbjct: 121 PEEKSFFKEGRRIASIYGFSYQARALMENQAARYRRSTDAPFHIGMLHGTLSGSEGHDPY 180 Query: 180 APCSTSDLLGSGFRYWALGHIHKRSTIEGSC-AIVMPGIPQGRDIGESGPKSVTLASVLD 238 P + DL+ SG YWALGHIHKR + A++ PG Q R I E+G K L V Sbjct: 181 CPFTHDDLVKSGMDYWALGHIHKRQVLSAEHPAVIYPGNTQARHIKETGDKGYYLVHVT- 239 Query: 239 DGSIALEERIVSLAQFERVGLDASGTATWHDLVARLETSLQDAATRSVSDHLVVRLAISG 298 +G I+ E + +E+ +D + L +E + + R + VRL + G Sbjct: 240 NGDISYEFQRAHDVLWEKAAVDVTEAKNMTALFQMVEDTF--SKLRKKGSPVCVRLVLQG 297 Query: 299 TTP 301 T P Sbjct: 298 TAP 300 >SA1662 [L] COG0420 DNA repair exonuclease Sau Staphylococcus aureus N315 Length = 398 Score = 140 bits (352), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 72/231 (31%), Positives = 121/231 (52%), Gaps = 5/231 (2%) Query: 5 RFVHAADIHLDSPLRSLALRDPELADFISNASRQVFARIIDLCLEERVQALLLAGDLYDG 64 +F+H +D+HLDSP +S + P++ + + ++ + F I+D+ L++ V +++AGDL+D Sbjct: 3 KFIHCSDLHLDSPFKSKSHISPKIFEDVQKSAYESFKNIVDIALQQDVDFVIIAGDLFDS 62 Query: 65 DQTSMKTARFLGEQLRRLDAAGIRTFIIRGNHDAL-ARITKELVFPPNVHLFGGRAEAIE 123 + +++ FL +Q RL I ++ GNHD L ++I+ +P NV +F + E E Sbjct: 63 ENRTLRAEIFLKQQFERLQNEQIFVYVCHGNHDPLSSKISSN--WPDNVSVFSNKVETYE 120 Query: 124 VERDRGERSIVLHGLSFAKPHAPEGLLAKYRPPV-QDATNIGMMHTSLGGSPSHDVYAPC 182 GE +I +HG S+ + E + +Y Q +IG++H + S ++ Y Sbjct: 121 AITKSGE-TIYIHGFSYENRASYENKIDEYPSSQGQKGIHIGVLHGTYSKSSVNERYTEF 179 Query: 183 STSDLLGSGFRYWALGHIHKRSTIEGSCAIVMPGIPQGRDIGESGPKSVTL 233 DL + YWALGHIH+R + I G QGR E G K L Sbjct: 180 ILEDLNSKLYHYWALGHIHERQQLSDMPVINYSGNIQGRHFNEQGEKGCLL 230