BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0144.0028.p (628 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PAE3171 [O] COG0464 ATPases of the AAA+ class Pya Pyrobaculum ae... 109 2e-23 MJ1156 [O] COG0464 ATPases of the AAA+ class Mja Methanococcus j... 108 4e-23 AF1297 [O] COG0464 ATPases of the AAA+ class Afu Archaeoglobus f... 107 1e-22 AF2098 [O] COG0464 ATPases of the AAA+ class Afu Archaeoglobus f... 107 1e-22 MA4575 [O] COG0464 ATPases of the AAA+ class Mac Methanosarcina ... 107 1e-22 >PAE3171 [O] COG0464 ATPases of the AAA+ class Pya Pyrobaculum aerophilum Length = 738 Score = 109 bits (272), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 84/262 (32%), Positives = 121/262 (46%), Gaps = 27/262 (10%) Query: 217 EYGEAREWGLALGQRFRENSIRWDETGAG--TNALFGGPPGLGKTYFARIVANHLGVPLI 274 E E EW + F DE G L GPPG+GKT FA+ VA G I Sbjct: 476 ELREIVEWPMKYKHYF-------DELGVEPPKGILLFGPPGVGKTLFAKAVATESGANFI 528 Query: 275 STSISGIFATSAGYLDSVIKGVREVFAKAEASAPCAILWDELDAL-PSRENLNDNNSRSN 333 + + + G + K +REVF KA +APC I +DE+D++ P+R SR Sbjct: 529 AVRGPELLSKWVGESE---KAIREVFKKARMAAPCVIFFDEIDSIAPAR------GSRLG 579 Query: 334 SASWWTPVIAEFLLQLDSAAVGRRRAVFVWAASNHPHRVDPALLRPGRLDRVIHFRPPGP 393 + ++ + L ++D +G + V V AA+N P +DPALLRPGR DRVI+ PP Sbjct: 580 DSGVTDRMVNQLLAEMD--GIGTLKNVVVMAATNRPDILDPALLRPGRFDRVIYVPPPDL 637 Query: 394 DGIVSIARHHLG----ADLPEVDLTAIGQLGVGRSPAEIAAAVSSARXTSTRRPSGGSRT 449 + I + H AD +V+L + + G + A+IAA V A + R Sbjct: 638 KARIEIFKVHTKRVKLAD--DVNLEELAKRTEGYTGADIAALVREAAMLALRETIREKTV 695 Query: 450 TSPATSSRRSRSASTRSWPSTS 471 + S + A R PS + Sbjct: 696 KAKPVSMKHFEEALKRIPPSLT 717 Score = 87.4 bits (215), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 72/212 (33%), Positives = 105/212 (49%), Gaps = 33/212 (15%) Query: 249 LFGGPPGLGKTYFARIVANHLGVPLISTSISGIFATSAGYLDSVIKGVREVFAKAEASAP 308 L GPPG GKT A+ VAN ++ I+G S Y +S + +RE+F +A+ +AP Sbjct: 215 LLIGPPGTGKTLLAKAVANEANAYFVA--INGPEIMSKYYGESEAR-LREIFEEAKKNAP 271 Query: 309 CAILWDELDAL-PSRENLNDNNSRSNSASWWTPVIAEFLLQLDSAAVGRRRAVFVWAASN 367 I DE+DA+ P RE + + V+A+ L +D + R V V A+N Sbjct: 272 AIIFIDEIDAIAPKREEVTGEVEKR--------VVAQLLTLMD--GLQERGQVIVIGATN 321 Query: 368 HPHRVDPALLRPGRLDRVIHFRPPGPDG-----IVSIARHHL----GADLP--------E 410 P VDPAL RPGR DR IH P PD I+++ ++ AD+ E Sbjct: 322 RPDAVDPALRRPGRFDREIHI--PMPDKRARREILAVHTRNMPLCTKADVETKICNPGDE 379 Query: 411 VDLTAIGQLGVGRSPAEIAAAVSSARXTSTRR 442 VDL I ++ G + A++AA A T+ R+ Sbjct: 380 VDLDRIAEMTHGYTGADLAALAKEAAMTALRK 411 >MJ1156 [O] COG0464 ATPases of the AAA+ class Mja Methanococcus jannaschii Length = 903 Score = 108 bits (270), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 83/232 (35%), Positives = 112/232 (48%), Gaps = 20/232 (8%) Query: 217 EYGEAREWGLALGQRFRENSIRWDETGAGTNALFGGPPGLGKTYFARIVANHLGVPLIST 276 E EA EW L + F + +R L GPPG GKT A+ VAN G IS Sbjct: 463 ELREAVEWPLKAKEVFEKIGVR-----PPKGVLLFGPPGTGKTLLAKAVANESGANFISV 517 Query: 277 SISGIFATSAGYLDSVIKGVREVFAKAEASAPCAILWDELDAL-PSRENLNDNNSRSNSA 335 IF+ G + K +RE+F KA SAPC I +DE+DA+ P R R S+ Sbjct: 518 KGPEIFSKWVGESE---KAIREIFRKARQSAPCIIFFDEIDAIAPKR-------GRDLSS 567 Query: 336 SWWTPVIAEFLLQLDSAAVGRRRAVFVWAASNHPHRVDPALLRPGRLDRVIHFRPPGPDG 395 + V+ + L +LD + + V V AA+N P +DPALLRPGRLDRVI P Sbjct: 568 AVTDKVVNQLLTELD--GMEEPKDVVVIAATNRPDIIDPALLRPGRLDRVILVPVPDEKA 625 Query: 396 IVSIARHHL-GADLPE-VDLTAIGQLGVGRSPAEIAAAVSSARXTSTRRPSG 445 + I + H +L E V+L + + G + A+I A A + R G Sbjct: 626 RLDIFKIHTRSMNLAEDVNLEELAKKTEGYTGADIEALCREAAMLAVRESIG 677 Score = 80.1 bits (196), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/199 (32%), Positives = 95/199 (47%), Gaps = 18/199 (9%) Query: 248 ALFGGPPGLGKTYFARIVANHLGVPLISTSISGIFATSAGYLDSVIKGVREVFAKAEASA 307 L GPPG GKT A+ VAN G + I + G + + +R++F +AE +A Sbjct: 216 VLLVGPPGTGKTLLAKAVANEAGANFYVINGPEIMSKYVGETE---ENLRKIFEEAEENA 272 Query: 308 PCAILWDELDAL-PSRENLNDNNSRSNSASWWTPVIAEFLLQLDSAAVGRRRAVFVWAAS 366 P I DE+DA+ P R+ R ++A+ L +D + R V V A+ Sbjct: 273 PSIIFIDEIDAIAPKRDEATGEVERR--------LVAQLLTLMD--GLKGRGQVVVIGAT 322 Query: 367 NHPHRVDPALLRPGRLDRVIHFRPPGPDGIVSIARHHLGADLP---EVDLTAIGQLGVGR 423 N P+ +DPAL RPGR DR I P +G I + H ++P +VDL + + G Sbjct: 323 NRPNALDPALRRPGRFDREIVIGVPDREGRKEILQIH-TRNMPLAEDVDLDYLADVTHGF 381 Query: 424 SPAEIAAAVSSARXTSTRR 442 A++AA A + RR Sbjct: 382 VGADLAALCKEAAMRALRR 400 >AF1297 [O] COG0464 ATPases of the AAA+ class Afu Archaeoglobus fulgidus Length = 733 Score = 107 bits (266), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 83/262 (31%), Positives = 120/262 (45%), Gaps = 20/262 (7%) Query: 217 EYGEAREWGLALGQRFRENSIRWDETGAGTNALFGGPPGLGKTYFARIVANHLGVPLIST 276 E EA EW L + FR +I+ L GPPG GKT A+ VAN IS Sbjct: 466 ELMEAVEWPLKYPEVFRAANIK-----PPRGILLFGPPGTGKTLLAKAVANESNANFISV 520 Query: 277 SISGIFATSAGYLDSVIKGVREVFAKAEASAPCAILWDELDAL-PSRENLNDNNSRSNSA 335 + + G + K VRE+F KA APC I +DE+D+L P R + D++ Sbjct: 521 KGPELLSKWVGESE---KHVREMFRKARQVAPCVIFFDEIDSLAPRRGGIGDSHVTER-- 575 Query: 336 SWWTPVIAEFLLQLDSAAVGRRRAVFVWAASNHPHRVDPALLRPGRLDRVIHFRPPGPDG 395 V+++ L +LD + + V V AA+N P +DPALLRPGRL+R I+ PP Sbjct: 576 -----VVSQLLTELD--GLEELKDVVVIAATNRPDMIDPALLRPGRLERHIYIPPPDKKA 628 Query: 396 IVSIARHHL-GADLP-EVDLTAIGQLGVGRSPAEIAAAVSSARXTSTRRPSGGSRTTSPA 453 V I + HL G L +V++ + + G S A+I A A + R T A Sbjct: 629 RVEIFKIHLRGKPLADDVNIEELAEKTEGYSGADIEAVCREAGMLAIRELIKPGMTREEA 688 Query: 454 TSSRRSRSASTRSWPSTSSATR 475 + + + + + R Sbjct: 689 KEAAKKLKITKKHFEEALKKVR 710 Score = 87.0 bits (214), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 71/201 (35%), Positives = 96/201 (47%), Gaps = 22/201 (10%) Query: 248 ALFGGPPGLGKTYFARIVANHLGVPLISTSISGIFATSAGYLDSVIKGVREVFAKAEASA 307 L GPPG GKT A+ VAN + I ISG S Y +S + +RE+F +A+ +A Sbjct: 219 VLLYGPPGTGKTLIAKAVANEVDAHFIP--ISGPEIMSKYYGESE-QRLREIFEEAKENA 275 Query: 308 PCAILWDELDAL-PSRENLNDNNSRSNSASWWTPVIAEFLLQLDSAAVGRRRAVFVWAAS 366 P I DE+D++ P RE + R V+A+ L +D + R V V AA+ Sbjct: 276 PSIIFIDEIDSIAPKREEVTGEVERR--------VVAQLLALMD--GLEARGDVIVIAAT 325 Query: 367 NHPHRVDPALLRPGRLDRVIHFRPPGPDGIVSIARHH-----LGADLPEVDLTAIGQLGV 421 N P +DPAL RPGR DR I P +G I H L D VDL + +L Sbjct: 326 NRPDAIDPALRRPGRFDREIEIGVPDKEGRKEILEIHTRKMPLAED---VDLEELAELTN 382 Query: 422 GRSPAEIAAAVSSARXTSTRR 442 G A++ A A + RR Sbjct: 383 GFVGADLEALCKEAAMHALRR 403 >AF2098 [O] COG0464 ATPases of the AAA+ class Afu Archaeoglobus fulgidus Length = 811 Score = 107 bits (266), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 82/261 (31%), Positives = 118/261 (45%), Gaps = 25/261 (9%) Query: 217 EYGEAREWGLALGQRFRENSIRWDETGAGTNALFGGPPGLGKTYFARIVANHLGVPLIST 276 E EA EW L ++F++ I+ L GPPG GKT A+ VAN IS Sbjct: 545 EIIEAVEWPLKYPEKFKKFGIK-----PPKGVLLYGPPGTGKTLIAKAVANESEANFISI 599 Query: 277 SISGIFATSAGYLDSVIKGVREVFAKAEASAPCAILWDELDALPSRENLNDNNSRSNSAS 336 I + G + K VR++F KA APC I +DE+DA+ + D SR+ Sbjct: 600 KGGQILSKWLGESE---KAVRKIFRKARQVAPCIIFFDEIDAIAQMRGI-DEGSRAVER- 654 Query: 337 WWTPVIAEFLLQLDSAAVGRRRAVFVWAASNHPHRVDPALLRPGRLDRVIHFRPPGPDGI 396 V+ + L ++D + V V A+N P +DPALLRPGR DR+++ RPP Sbjct: 655 ----VLNQLLTEMD--GLEELHGVVVIGATNRPDILDPALLRPGRFDRMVYVRPPDKKSR 708 Query: 397 VSIARHHLGADLP---EVDLTAIGQLGVGRSPAEIAAAVSSARXTSTRRPSGGSRTTSPA 453 ++I + H D+P +VDL + L G A+I A A + R + Sbjct: 709 LAIFKIH-TRDMPLSEDVDLEELADLTEGYVGADIEAICREAVMLAIR-----ENINAEK 762 Query: 454 TSSRRSRSASTRSWPSTSSAT 474 R A + PS + A Sbjct: 763 VEMRHFLEALKKIKPSVNEAM 783 Score = 80.1 bits (196), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 57/157 (36%), Positives = 79/157 (50%), Gaps = 14/157 (8%) Query: 248 ALFGGPPGLGKTYFARIVANHLGVPLISTSISGIFATSAGYLDSVIKGVREVFAKAEASA 307 L GPPG GKT A+ VAN +G + I+G S Y +S + +RE+F +A+ +A Sbjct: 234 VLLYGPPGTGKTLIAKAVANEIGASFFT--INGPEIMSKFYGESE-QRLREIFEEAKENA 290 Query: 308 PCAILWDELDAL-PSRENLNDNNSRSNSASWWTPVIAEFLLQLDSAAVGRRRAVFVWAAS 366 P I DE+D++ P RE + R V+A+ L +D + R V V A+ Sbjct: 291 PSIIFIDEIDSIAPKREEVTGEVERR--------VVAQLLTLMD--GLEERGQVIVIGAT 340 Query: 367 NHPHRVDPALLRPGRLDRVIHFRPPGPDGIVSIARHH 403 N VDPAL RPGR DR I P +G I + H Sbjct: 341 NRIDAVDPALRRPGRFDREIEIGVPDREGRYEIFQIH 377 >MA4575 [O] COG0464 ATPases of the AAA+ class Mac Methanosarcina acetivorans str.C2A Length = 753 Score = 107 bits (266), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 84/269 (31%), Positives = 125/269 (46%), Gaps = 28/269 (10%) Query: 217 EYGEAREWGLALGQRFRENSIRWDETGAGTNALFGGPPGLGKTYFARIVANHLGVPLIST 276 E E+ EW L + F+ +I+ L GPPG GKT A+ VA+ IS Sbjct: 459 ELIESVEWPLKYPEMFKAVNIK-----PPRGVLLFGPPGTGKTLLAKAVASESEANFISI 513 Query: 277 SISGIFATSAGYLDSVIKGVREVFAKAEASAPCAILWDELDAL-PSRENLNDNNSRSNSA 335 + + G + + +RE F KA+ +AP I +DE+D++ P R +++D + Sbjct: 514 KGPELLSKYVGESE---RAIRETFRKAKQAAPTVIFFDEIDSIAPERSSVSDTHVSER-- 568 Query: 336 SWWTPVIAEFLLQLDSAAVGRRRAVFVWAASNHPHRVDPALLRPGRLDRVIHFRPPGPDG 395 V+++ L +LD V + V + AA+N P VDPALLRPGR DR+I+ +PPG +G Sbjct: 569 -----VVSQILTELD--GVEELKDVIIVAATNRPDMVDPALLRPGRFDRLIYIKPPGKEG 621 Query: 396 IVSIAR-HHLGADLPE-VDLTAIGQLGVGRSPAEIAAAVSSARXTSTR--------RPSG 445 I H G L E V L+ + ++ G A+I A + R R S Sbjct: 622 REKIFEIHTKGKPLAEDVKLSELAEMTEGYVGADIEGICREAAMLALREIVTPGTDRKSI 681 Query: 446 GSRTTSPATSSRRSRSASTRSWPSTSSAT 474 + S R A R P+TS T Sbjct: 682 KEKAGDVRLSKRHFERAIRRVRPTTSRET 710 Score = 73.9 bits (180), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 68/198 (34%), Positives = 93/198 (46%), Gaps = 16/198 (8%) Query: 248 ALFGGPPGLGKTYFARIVANHLGVPLISTSISGIFATSAGYLDSVIKGVREVFAKAEASA 307 L GPPG GKT A+ VA+ I+ ISG S Y +S K +RE+F +AE A Sbjct: 213 VLLHGPPGTGKTMIAKAVASETDANFIT--ISGPEIVSKYYGESEQK-LREIFDEAEKDA 269 Query: 308 PCAILWDELDAL-PSRENLNDNNSRSNSASWWTPVIAEFLLQLDSAAVGRRRAVFVWAAS 366 P I DE+D++ P R + R V+A+ L +D + R V V AA+ Sbjct: 270 PSIIFIDEIDSIAPKRGEVTGEMERR--------VVAQLLSLMD--GLKSRGEVVVIAAT 319 Query: 367 NHPHRVDPALLRPGRLDRVIHFRPPGPDGIVSIARHHL-GADLP-EVDLTAIGQLGVGRS 424 N P+ +D AL R GR DR I P +G I H G L EV L I + G Sbjct: 320 NRPNSIDEALRRGGRFDREIEIGIPDRNGRRQILLIHTRGMPLEDEVSLGEIADVTHGFV 379 Query: 425 PAEIAAAVSSARXTSTRR 442 A++++ A + RR Sbjct: 380 GADLSSLCKEAAMHALRR 397