BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0144.0010.p (356 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb20705 [GER] COG0697 Permeases of the drug/metabolite transpor... 268 1e-71 AGc357 [GER] COG0697 Permeases of the drug/metabolite transporte... 256 6e-68 mlr5364 [GER] COG0697 Permeases of the drug/metabolite transport... 255 1e-67 AGc2870 [GER] COG0697 Permeases of the drug/metabolite transport... 128 2e-29 BMEII0677 [GER] COG0697 Permeases of the drug/metabolite transpo... 124 4e-28 >SMb20705 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 303 Score = 268 bits (686), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 148/288 (51%), Positives = 201/288 (69%), Gaps = 2/288 (0%) Query: 61 SYDDRSARLAGIGLMLLSIFMFSFGDAMGKFIVATYSVGQLLWLRACAALLVLLPIVW-Q 119 S ++ +AR AG+ +MLL + MFS D MGK++VATYSVGQ++ +R+ AA L+L P +W Sbjct: 11 SRENGAAR-AGVVVMLLGMLMFSVNDVMGKWLVATYSVGQVVLIRSIAAALLLAPFLWVS 69 Query: 120 RRADFLHLERPWLQLLRVTLSTVEVAAFFLATVYLPLADVITYYLAGPIFVTAMSGLVLG 179 LERP LQL RV ST EV AF+ A VYLPLADV+TY+LA PI+V A+S LVL Sbjct: 70 GPKKLFTLERPGLQLARVVASTAEVVAFYFAVVYLPLADVMTYWLAAPIYVAAVSPLVLK 129 Query: 180 EHIGWRRWTAILVGFCGVLIALRPSAQTISWPAMIALGGSLSFAVLMLITRSLRATPDIV 239 E +GWRRWTAI +GF GV++AL PS+Q + PA+I++ GS++FA +M+ RSLR TPD Sbjct: 130 EPVGWRRWTAIGIGFVGVVVALEPSSQAFTLPAVISILGSMTFAFMMISGRSLRGTPDTT 189 Query: 240 LATSQFGGTFILGLVLSPFGWVTPSAGSLVLFFTAGIISVAALLCVNRSLKLAPASVVVP 299 LA Q G + GLV +PF W L G +++ A + VNR+LKLA A+ V P Sbjct: 190 LAFWQIVGAAVAGLVWAPFDWTPLKPLDTALICLLGAVAMIAHVLVNRALKLADAATVAP 249 Query: 300 YQYSMIVWAVIFGFVVFGDVPSWATIIGAAIIIAAGLYIFVREQQLGR 347 QY+++ WA+ FG+++FGD P + +IGAA+I+A+GL+IF REQQL R Sbjct: 250 LQYTLLFWAIFFGWLIFGDTPRLSMVIGAALIVASGLFIFFREQQLKR 297 >AGc357 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 328 Score = 256 bits (654), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 137/289 (47%), Positives = 204/289 (70%), Gaps = 7/289 (2%) Query: 71 GIGLMLLSIFMFSFGDAMGKFIVATYSVGQLLWLRACAALLVLLPIVWQRR-ADFLHLER 129 G+ +MLL + +F+ DAMGK++V+TYS GQ++ +R+ AAL++L+PIVW+ + +++ER Sbjct: 34 GVAVMLLGMLLFALNDAMGKWLVSTYSQGQVILIRSAAALVILVPIVWRAGLSGLVNVER 93 Query: 130 PWLQLLRVTLSTVEVAAFFLATVYLPLADVITYYLAGPIFVTAMSGLVLGEHIGWRRWTA 189 P LQ+ RV ST E+ F+ A LPLADV+TY+LA PI+V A++ +LGE +GWRRWTA Sbjct: 94 PGLQVARVFFSTAELFCFYFAVASLPLADVMTYWLAAPIYVAALAPFLLGEKVGWRRWTA 153 Query: 190 ILVGFCGVLIALRPSAQTISWPAMIALGGSLSFAVLMLITRSLRATPDIVLATSQFGGTF 249 I +GF GVLIAL+PS+ +++ A+ ++ GS +FA +ML R LR TPD VLA Q G Sbjct: 154 IAIGFVGVLIALKPSSASLTSAALFSILGSAAFAFMMLSGRQLRNTPDTVLAFWQIIGAG 213 Query: 250 ILGLV---LSPFGWVTPSAGSLVLFFTA--GIISVAALLCVNRSLKLAPASVVVPYQYSM 304 + G+V ++P GW+ P S L F + G++++AA + VNR+LKLA A+ V P QY++ Sbjct: 214 LAGIVAVFMTPSGWL-PVQSSFDLAFLSLLGVVAMAAHVLVNRALKLADAATVAPLQYTL 272 Query: 305 IVWAVIFGFVVFGDVPSWATIIGAAIIIAAGLYIFVREQQLGRPDSAVN 353 ++WAVIFG++ F DVP + ++GA +I+ +GLYIF RE L R A + Sbjct: 273 LLWAVIFGWLFFNDVPQTSIVVGAGLIVFSGLYIFFRENTLKRRRDAAD 321 >mlr5364 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 307 Score = 255 bits (652), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 141/291 (48%), Positives = 200/291 (68%), Gaps = 4/291 (1%) Query: 65 RSARLAGIGLMLLSIFMFSFGDAMGKFIVATYSVGQLLWLRACAALLVLLPIV-WQRRAD 123 R+ LAGI LML F+F+ DAMGK++VA++SVGQ++ +R+ A VL P++ Q A Sbjct: 12 RNVLLAGILLMLAGDFLFALNDAMGKWLVASFSVGQVVLIRSIGAFFVLGPMIAHQGTAK 71 Query: 124 FLHLERPWLQLLRVTLSTVEVAAFFLATVYLPLADVITYYLAGPIFVTAMSGLVLGEHIG 183 +ERP LQ+LRV ++T++ A F+ A VYLPLADV+++Y+AGPI+V A+S L+LGE +G Sbjct: 72 LFRMERPELQILRVVMTTLDTALFYAAVVYLPLADVMSFYMAGPIYVAALSHLLLGEKVG 131 Query: 184 WRRWTAILVGFCGVLIALRPSAQTISWPAMIALGGSLSFAVLMLITRSLRATPDIVLATS 243 WRRW AIL+GFCGV+I L+PS+ S + AL GS++FA +++ R LR T D L T Sbjct: 132 WRRWVAILLGFCGVVIMLKPSSAAFSLSSSFALAGSIAFAFAIILNRRLRGTSDTNLVTW 191 Query: 244 QFGGTFILGLVLSPFGWVTPSAGSLVLFFTAGIISVAALLCVNRSLKLAPASVVVPYQYS 303 Q GT ++G VL+ W TPSA GI+S +A L + R+LKLAPAS + P Y+ Sbjct: 192 QTIGTLLVGGVLTIGAWQTPSALDFGAMLLLGIVSCSAHLMITRALKLAPASTLAPLHYT 251 Query: 304 MIVWAVIFGFVVFGDVPSWATIIGAAIIIAAGLYIFVREQQLGRPDSAVNP 354 +++WAV+FG V FGDVP +IG+ II+ AGL+IF R++ + D+ V P Sbjct: 252 LLLWAVVFGLVFFGDVPGPRILIGSGIIVLAGLFIFHRQKVV---DTTVPP 299 >AGc2870 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 311 Score = 128 bits (322), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 92/284 (32%), Positives = 145/284 (51%), Gaps = 18/284 (6%) Query: 86 DAMGKFIVAT--YSVGQLLWLRACAALLVLLPIVWQ-RRADFLHLERPWLQLLRVTLSTV 142 DA+ K++ + S Q+ + R +L LP++ +RPW+ LR L Sbjct: 28 DAIAKYMAVSVGMSPAQVTFYRFFFQVLCTLPLLLVVSPGALFSAKRPWMNCLRGVLHAS 87 Query: 143 EVAAFFLATVYLPLADVITYYLAGPIFVTAMSGLVLGEHIGWRRWTAILVGFCGVLIALR 202 FF A Y+PLADV Y P +T MS L LG+ +GW+RWTAI+VGF G LI ++ Sbjct: 88 ASLMFFAAVKYMPLADVFAIYFVEPFMLTMMSALFLGDRVGWKRWTAIVVGFGGALIVIQ 147 Query: 203 PSAQTISWPAMIALGGSLSFAVLMLITRSL--RATPDIVLATSQFGGTFILGLVL----- 255 PS + W +++ + + + + + + R++ +P ++ S GT + L Sbjct: 148 PSFEIFGWTSLLPVACAFFYTLYLFLNRAIGDADSPLVMQTMSGIAGTLFMAAALFAGDA 207 Query: 256 ---SPFGWVTP-SAGSLVLFFTAGIISVAALLCVNRSLKLAPASVVVPYQYSMIVWAVIF 311 F P SA +LVL G +S L + R+ +LAP S++ P+QY I+ A I Sbjct: 208 LGDKDFAVSLPQSAFALVLLVLLGSLSGYMHLLIVRAFRLAPLSLLAPFQYFEIISATIL 267 Query: 312 GFVVFGDVPSWATIIGAAIIIAAGLYIFVREQQLGRPDSAVNPP 355 G+ +F D P+ + +G II+A+GL+I RE+Q A PP Sbjct: 268 GYALFSDFPTPSKWLGILIIVASGLFIIWRERQ----QPASTPP 307 >BMEII0677 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bme Brucella melitensis Length = 309 Score = 124 bits (310), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 90/299 (30%), Positives = 153/299 (51%), Gaps = 26/299 (8%) Query: 66 SARLAGIGLMLLSIFMFSFGDAMGKFI---------VATYSVGQLLWLRACAALLVLLPI 116 A + G+G M+LS+ M DA+GK++ AT+ + + C + ++ + Sbjct: 10 EAHVKGMGFMVLSVLMLPLMDAIGKWLAMMDDLPPATATF----MRFFVQCWLMFFIILV 65 Query: 117 VWQRRADFLHLERPWLQLLRVTLSTVEVAAFFLATVYLPLADVITYYLAGPIFVTAMSGL 176 V RA L LLR L FF A Y+PLAD + + A P+ +T S L Sbjct: 66 VGGLRA--LATSHLMGNLLRGALMGFGGLCFFTAVKYMPLADALAVFFAEPLILTLFSAL 123 Query: 177 VLGEHIGWRRWTAILVGFCGVLIALRPSAQTISWPAMIALGGSLSFAVLMLITRSL--RA 234 L E +GWRR++A+ +G G +I ++PS + +++ L +++FA+ +++ R + Sbjct: 124 FLKEKVGWRRFSAVGIGLIGTMIVIQPSFEIFGMVSLLPLATAVTFAIYLILNRKYGAKE 183 Query: 235 TPDIVLATSQFGGTFILGLVL--------SPFGWVTP-SAGSLVLFFTAGIISVAALLCV 285 +P + + GG +G+ + + P S +L G I + L V Sbjct: 184 SPLTMQLYAGLGGWLFVGVAMLLAADRSFDDMHFALPHSVQPWLLLLLLGTIGTVSHLIV 243 Query: 286 NRSLKLAPASVVVPYQYSMIVWAVIFGFVVFGDVPSWATIIGAAIIIAAGLYIFVREQQ 344 ++ KLAPAS++ P+QY IV AV+ G ++FGD P+ + +G AIII +G Y+F+RE + Sbjct: 244 VQASKLAPASMLAPFQYLEIVNAVLMGLIIFGDFPTPSKWLGIAIIIGSGFYVFMRESK 302