BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0143.0064.p (309 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc00642 [GER] COG0697 Permeases of the drug/metabolite transpor... 191 2e-48 AGc4446 [GER] COG0697 Permeases of the drug/metabolite transport... 189 1e-47 mlr3874 [GER] COG0697 Permeases of the drug/metabolite transport... 177 3e-44 PM1698 [GER] COG0697 Permeases of the drug/metabolite transporte... 133 5e-31 PA4287 [GER] COG0697 Permeases of the drug/metabolite transporte... 126 7e-29 >SMc00642 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 296 Score = 191 bits (485), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 106/289 (36%), Positives = 170/289 (58%), Gaps = 2/289 (0%) Query: 20 QPYLLLCITATCWAGNAIVGRLAAGHIPPVTLSFLRWSAAFLIILPFAWKHLVRDWPVIR 79 + Y L ITA W GN++ G++A GH+ P+ L+ LRW A +IL + RDW IR Sbjct: 4 RAYFYLGITALFWGGNSVAGKMAVGHVSPMMLTTLRWLLALAVILVLMTPQIRRDWQKIR 63 Query: 80 NNLGIMVLMSITGISAFNTLQYWALEHTQALNTLLLQSAAPLVVALWSLILLGARLTLAQ 139 + ++ G + FN Y A+++T A+N ++LQ+ P+++ +++ L + +LAQ Sbjct: 64 QHWLQLLAYGAVGFTMFNAFLYSAVQYTSAINAVILQAGIPMLIFIFNFALFKMKASLAQ 123 Query: 140 LFGVLLSLAGVLVILLHGDLTTLSRIEFNKGDLIFIVALVIFALYSVLTLKRPNIHGLS- 198 + G ++L GVL+ HGDL +L R+ FN GD + I+A +++A Y+V +P +H S Sbjct: 124 VIGFTVTLVGVLITAAHGDLASLMRLSFNFGDALMILACIVYAAYTVALRWKPAMHWQSF 183 Query: 199 VAAFTFGCGALVLIPLYIWELGARPVMQLTINNLLSLFYVAVFPSTLAYLCFNRGVQLIG 258 +AA FG L IPL +WE+G + + Y A+FPS ++ + + RGV++IG Sbjct: 184 IAAPAFGA-LLSAIPLLLWEMGKGTAIMPDATGWAIVIYAAIFPSLMSQVLYVRGVEMIG 242 Query: 259 ANRAAPFFHMVPVFGTIMSIVFIGEHPQAFHFIGFALVLAGVFAASRKQ 307 ANRA F + +PVFGT++S++ +GE FH ALVL G+ A R + Sbjct: 243 ANRAGLFINAIPVFGTLLSVLLVGEIFHPFHLAALALVLGGIAIAERGR 291 >AGc4446 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 302 Score = 189 bits (479), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 95/292 (32%), Positives = 167/292 (57%) Query: 17 IANQPYLLLCITATCWAGNAIVGRLAAGHIPPVTLSFLRWSAAFLIILPFAWKHLVRDWP 76 + ++ YL L I CW GN + G+LA GHI P+ +FLRW A II + L++DWP Sbjct: 8 VPSKAYLALIIATLCWGGNTVAGKLAVGHISPMAFTFLRWVLAVAIIFAISVPQLIKDWP 67 Query: 77 VIRNNLGIMVLMSITGISAFNTLQYWALEHTQALNTLLLQSAAPLVVALWSLILLGARLT 136 V++ L ++ G +AFN Y AL+HT A+N ++Q+ P+V+ + + +L R+ Sbjct: 68 VVKQRLPYFFVLGSVGYTAFNVFLYTALQHTSAINAAVIQAGIPMVIFVLNFVLFRTRVL 127 Query: 137 LAQLFGVLLSLAGVLVILLHGDLTTLSRIEFNKGDLIFIVALVIFALYSVLTLKRPNIHG 196 Q+ G L+++GV ++ HGD +L ++E N GD + ++A++++A+Y+V+ +P + Sbjct: 128 FGQIAGFCLTISGVALLASHGDPLSLLQLEMNVGDAVMLLAVLVYAIYTVILRWKPAVDW 187 Query: 197 LSVAAFTFGCGALVLIPLYIWELGARPVMQLTINNLLSLFYVAVFPSTLAYLCFNRGVQL 256 ++ A L +PL +E+ ++ + + Y +F S +A + + +GV+ Sbjct: 188 RTLMAIPAFFALLTSVPLVFFEMSRESLIWPDQKGWMLVVYAGIFASLIAQILYIKGVEQ 247 Query: 257 IGANRAAPFFHMVPVFGTIMSIVFIGEHPQAFHFIGFALVLAGVFAASRKQS 308 IGANRA F ++VPVFGT++S+ + E + + LAG+ A RK+S Sbjct: 248 IGANRAGLFINLVPVFGTLLSVFVLSETLHTYQIAALFMALAGIAVAERKKS 299 >mlr3874 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 303 Score = 177 bits (449), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 101/283 (35%), Positives = 166/283 (58%), Gaps = 2/283 (0%) Query: 19 NQPYLLLCITATCWAGNAIVGRLAAGHIPPVTLSFLRWSAAFLIILPFAWKHLVRDWPVI 78 YLLL +T W GN++ G+LA H+ P+ L FLRW A I+LP W+ + +DWPV+ Sbjct: 3 RHAYLLLLLTTLLWGGNSVAGKLAVDHVSPMMLVFLRWVLAVAILLPIGWRSIQQDWPVV 62 Query: 79 RNNLGIMVLMSITGISAFNTLQYWALEHTQALNTLLLQSAAPLVVALWSLILLGARLTLA 138 R + I+ + +G + FN + Y AL +T A+N + Q+A P+++ + + R+ A Sbjct: 63 RRHWLILAALGASGFTLFNVIFYTALNYTTAINVSIEQAAMPILIMTANFVFFRLRVNWA 122 Query: 139 QLFGVLLSLAGVLVILLHGDLTTLSRIEFNKGDLIFIVALVIFALYSVLTLKRPNIHGLS 198 Q+ GV+L++AGV++ HGD L +E N GD I +VA+V+++ YSV +P + S Sbjct: 123 QIAGVVLTIAGVILTACHGDPRRLLTLELNFGDAIMLVAVVLYSGYSVGLRLKPALRWQS 182 Query: 199 VAAFTFGCGALVL-IPLYIWELGARPVMQLTINNLLSLFYVAVFPSTLAYLCFNRGVQLI 257 + T AL+ +P +WE+ A V+ + Y A+ S ++ + + RG +LI Sbjct: 183 L-MLTMSIAALITSLPFLLWEVAAGTVVVPDARGWTVIVYTAIGASVVSQITYIRGNELI 241 Query: 258 GANRAAPFFHMVPVFGTIMSIVFIGEHPQAFHFIGFALVLAGV 300 GANRA F ++VP+FGT++S++ +GE Q + + LVL G+ Sbjct: 242 GANRAGLFINLVPIFGTLLSVLIVGETFQLYQALALVLVLGGI 284 >PM1698 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pmu Pasteurella multocida Length = 301 Score = 133 bits (335), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 86/292 (29%), Positives = 150/292 (51%), Gaps = 4/292 (1%) Query: 22 YLLLCITATCWAGNAIVGRLAAGHIPPVTLSFLRWSAAFLIILPFAWKHLVRDWPVIRNN 81 Y L + W GN + G++ + IPP+ L++ RW A LI+L K + PVIR + Sbjct: 9 YFCLLLATFFWGGNYLFGKILSTDIPPIVLNYARWFPAALILLLLFSKRSCQFTPVIRQH 68 Query: 82 LGIMVLMSITGISAFNTLQYWALEHTQALNTLLLQSAAPLVVALWSLILLGARLTLAQLF 141 I++ +S+ GI F Y L+ T +LN + + P+ V + ++ G + L Sbjct: 69 WRILIALSLLGIVIFPVFLYQGLQTTTSLNASIYLAVVPIFVLFLNRLVFGDPINFTGLT 128 Query: 142 GVLLSLAGVLVILLHGDLTTLSRIEFNKGDLIFIVALVIFALYSVLTLKRPNIHGLSVAA 201 G L S GVL +L GD+ L+++E N+GDL + + + +++Y L +P +V Sbjct: 129 GALFSFVGVLWLLSRGDIQRLTQLEVNQGDLWALGSALSWSIYCCLIRLKPAQLPNTVLL 188 Query: 202 FTFGCGALVLI-PLYIWELGARP---VMQLTINNLLSLFYVAVFPSTLAYLCFNRGVQLI 257 T C A++L PL+IW+ P LT + Y+ + PS L+Y +N G+ L+ Sbjct: 189 TTLVCMAMLLFTPLFIWQYQQLPPAFFSTLTPTQYSIITYLIIGPSILSYGFWNYGISLV 248 Query: 258 GANRAAPFFHMVPVFGTIMSIVFIGEHPQAFHFIGFALVLAGVFAASRKQSA 309 GA++ A F + P+F ++ ++ + E +H I L++ G+ +RK + Sbjct: 249 GADKGAAFTNATPLFAALLGVLVLNEALAFYHMISAGLIITGLLLCNRKSCS 300 >PA4287 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 296 Score = 126 bits (316), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 95/287 (33%), Positives = 144/287 (50%), Gaps = 11/287 (3%) Query: 22 YLLLCITATCWAGNAIVGRLAAGHIPPVTLSFLRWSAAFLIILPFAWKHLVRDWPVIRNN 81 YL + WAGN +V +LA G I P + F RW L + PF ++R+ I N Sbjct: 3 YLFPLLAVFIWAGNTVVNKLAVGIIQPAEIGFFRWLLVGLALTPFMLGPVLRNRRYILAN 62 Query: 82 LGIMVLMSITGISAFNTLQYWALEHTQALNTLLLQSAAPLVVALWSLILLGARLTLAQLF 141 LG V++ + G++ + +L Y+A T A N ++ S PL+ + +L RL L Sbjct: 63 LGKFVVLGLLGMAVYQSLAYYAAALTSATNMGIILSLMPLMSLGLASSILAHRLNAGALL 122 Query: 142 GVLLSLAGVLVILLHGDLTTLSRIEFNKGDLIFIVALVIFALYSVL----TLKRPNIHGL 197 G L+SLAGV++++ G L L N GD + IVA + +A+YSVL +LK P + L Sbjct: 123 GALVSLAGVVLVISQGHLGALLEHGVNLGDAMMIVATLAYAVYSVLLKKWSLKLPAMQLL 182 Query: 198 SVAAFTFGCGALVLIPLYIWELGARPVMQLTINNLLSLFYVAVFPSTLAYLCFNRGVQLI 257 + LV I + P L NL + Y A+F S +A L + GV + Sbjct: 183 YLQ-------VLVAILALLPLYLLSPRTGLNAANLPLVLYAALFASIVAALAWMHGVARL 235 Query: 258 GANRAAPFFHMVPVFGTIMSIVFIGEHPQAFHFIGFALVLAGVFAAS 304 G +R A FF+++P+ ++ + +GE H +G AL LAGV A Sbjct: 236 GPSRMALFFNLLPIITACIATLVLGERLTVHHLVGGALTLAGVLLAE 282