BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0140.0007.p (267 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ywtE [R] COG0561 Predicted hydrolases of the HAD superfamily ... 101 2e-21 lin0298 [R] COG0561 Predicted hydrolases of the HAD superfamily ... 96 7e-20 lin0302 [R] COG0561 Predicted hydrolases of the HAD superfamily ... 94 4e-19 lin2847 [R] COG0561 Predicted hydrolases of the HAD superfamily ... 93 6e-19 VC1364 [R] COG0561 Predicted hydrolases of the HAD superfamily V... 93 7e-19 >BS_ywtE [R] COG0561 Predicted hydrolases of the HAD superfamily Bsu Bacillus subtilis Length = 286 Score = 101 bits (252), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 79/283 (27%), Positives = 135/283 (47%), Gaps = 30/283 (10%) Query: 7 VVSDVDGTLLTKDKTLTDGARAAVRRLHEAGIGFTIVSSRPTIGMGFLIAPLAITQPIGA 66 + D+DGTLL K+ ++ R A++R +AGI TI + R T + L+ L I PI A Sbjct: 4 IAIDLDGTLLNKESVISAENREAIKRAVDAGILVTICTGRATFDVKALLDDLDI--PIIA 61 Query: 67 FNGSSIVDPQLKPLEQHLIPAAVAKRCIDMLHERGVDIWLFTNDRWLT------------ 114 NG +I D + + + L+ K D L + + ++T+D L+ Sbjct: 62 ANGGTIHDTGYRLISRTLMDQEAGKAIADYLLSKNIYFEVYTDDHLLSPFDGEAKLHAEL 121 Query: 115 -----RNPD--------GEYTAHEQHTIKHDPTIVSDFTPYLDQACKIVGASSDAALLRR 161 NP+ G T +Q IK P I S F + K++ S D L++ Sbjct: 122 DILKSANPNEQTDDLWQGAMTQFKQFGIKPIPHIESVFDGG-ENIYKLLCFSFDMDKLKQ 180 Query: 162 GEVEMQQMVGRDATAVRSQTYYLDVTPPGHDKGTFVEGIAKRLGVPLENVATIGDMQNDL 221 + E++ + S + +++ P KG + +A G+ +++ IGD NDL Sbjct: 181 AKEELKHH--KKLAQTSSGKHIIEILPASSGKGRALTKLADIYGIETQDIYAIGDSPNDL 238 Query: 222 PMFARSGVSFAMGNASDDVKARATHVTETNEQDGFAHAMDTVL 264 MF +G AM NA D++K ++T VT++N+++G A+ +D +L Sbjct: 239 SMFEVAGHRIAMENAIDELKEKSTFVTKSNDENGVAYFIDQLL 281 >lin0298 [R] COG0561 Predicted hydrolases of the HAD superfamily Lin Listeria innocua Length = 270 Score = 96.3 bits (238), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 73/266 (27%), Positives = 124/266 (46%), Gaps = 17/266 (6%) Query: 6 LVVSDVDGTLLTKDKTLTDGARAAVRRLHEAGIGFTIVSSRPTIGMGFLIAPLAITQP-- 63 L+ D+DGTLLT D +TD + A+R+ G+ + + RP +G+ + L + + Sbjct: 4 LIAIDIDGTLLTDDHKVTDEVKEAIRQAKLKGVKVVLCTGRPLVGVENYLTDLELREEGD 63 Query: 64 -IGAFNGSSIVDPQLKPLEQHL-IPAAVAKRCIDMLHERGVDIWLFTNDRWLTRNPD-GE 120 + +FNG+ + D K + HL + K + + + + F + T N + G+ Sbjct: 64 YVISFNGAFVQDTYTKEVISHLTLGIDDLKEIYQVSLDSNLHMHFFDDKALYTPNREIGK 123 Query: 121 YTAHE------QHTIKHDPTIVSDFTPYLDQACKIVGASSDAALLRRGEVEMQQMVGRDA 174 YT E Q K + DF + +A I +A L G +M + Sbjct: 124 YTIVEAYLTGSQLIYKEIENVPEDFI--MSKAMFI----EEAPELEAGIAKMPESFREKY 177 Query: 175 TAVRSQTYYLDVTPPGHDKGTFVEGIAKRLGVPLENVATIGDMQNDLPMFARSGVSFAMG 234 VRS +YL++ KG V+ ++++LG+ V IGD +ND+ M +G+ AMG Sbjct: 178 HLVRSTPFYLEILNRDASKGNAVKELSEKLGIKQSEVICIGDQENDVTMLEFAGLGIAMG 237 Query: 235 NASDDVKARATHVTETNEQDGFAHAM 260 NA + +K A + T +N G A A+ Sbjct: 238 NAPERIKQLADYTTASNNDSGVAKAI 263 >lin0302 [R] COG0561 Predicted hydrolases of the HAD superfamily Lin Listeria innocua Length = 273 Score = 93.6 bits (231), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 77/272 (28%), Positives = 126/272 (46%), Gaps = 26/272 (9%) Query: 1 MTRIALVVSDVDGTLLTKDKTLTDGARAAVRRLHEAGIGFTIVSSR---PTIGMGFLIAP 57 MT L+ SD+DGTLL +D+T+++ R ++ L G F+I + R +GF ++ Sbjct: 1 MTNKYLICSDIDGTLLRQDQTVSEKTRDLIQTLENDGHIFSISTGRMYRSAREVGFQVSK 60 Query: 58 LAITQPIGAFNGSSIVDPQLKPLEQHLIPAAVAKRCIDMLHERGVDIWLF-TNDRWLTRN 116 + + A NGS + L+ L A+ + D++ + + ++ F TN + T+ Sbjct: 61 ---SGHVIASNGSYAAIRDEEFLKTTLEEKAI-RETYDIMRDFDLPLFFFSTNTLFYTKE 116 Query: 117 P-------------DGEYTAHEQHTIKHDPTIVSDFTPYLDQACKIVGASSDAALLRRGE 163 P D + + +I + +L+ IV + D + L Sbjct: 117 PPEFFRELADKSRLDTGHNSFSLVSINDSHVFDENMNQFLN---AIVVSEDDTSRLADVR 173 Query: 164 VEMQQMVGRDATAVRSQTYYLDVTPPGHDKGTFVEGIAKRLGVPLENVATIGDMQNDLPM 223 + Q G + S L++ P DK T VE + K G+P E + T GD +ND+ M Sbjct: 174 QALNQANG--IRVLSSHHNNLEILPANSDKKTAVEALGKYYGIPRERIITFGDGENDIGM 231 Query: 224 FARSGVSFAMGNASDDVKARATHVTETNEQDG 255 +G AM NASD+VKA A +T+TNE DG Sbjct: 232 IQYAGTGVAMANASDNVKAAANQLTDTNEADG 263 >lin2847 [R] COG0561 Predicted hydrolases of the HAD superfamily Lin Listeria innocua Length = 279 Score = 93.2 bits (230), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 68/281 (24%), Positives = 126/281 (44%), Gaps = 21/281 (7%) Query: 1 MTRIALVVSDVDGTLLTKDKTLTDGARAAVRRLHEAGIGFTIVSSRPTIGMGFLIAPLAI 60 MT A+++ D+DGTLL K ++ + A+ + G+ + S RPT GM L + Sbjct: 1 MTTQAIIL-DIDGTLLNDGKKISPETKKALITAQQNGVKLILASGRPTTGMHAYAEQLEM 59 Query: 61 TQPIG---AFNGSSIVDPQL-KPLEQHLIPAAVAKRCIDMLHERGVDI------WLFTND 110 + G ++NG+ +VD + L + A K ++ + + V + +++TND Sbjct: 60 DKHHGLLVSYNGAKVVDCATNEELFNQALTVAEGKAVLEHMKQFEVKVMIDKEDYMYTND 119 Query: 111 RWLTRNPDGEYTAHEQHTIKHDP-------TIVSDFTPYLDQACKIVGASSDAALLRRGE 163 + P Y + I+++ D +LD + + D A ++ Sbjct: 120 VYDCYVP---YRGEVINIIQYESRGGNFKLCEKDDLAAFLDYRLSKILTAGDPAYMQENY 176 Query: 164 VEMQQMVGRDATAVRSQTYYLDVTPPGHDKGTFVEGIAKRLGVPLENVATIGDMQNDLPM 223 M V + +Y + T G DK ++ + +G+ EN+ GD ND+ M Sbjct: 177 QAMMAPFKNTLNCVFTADFYFEFTAQGIDKAKALDTVLTPMGIHAENIIAFGDGHNDITM 236 Query: 224 FARSGVSFAMGNASDDVKARATHVTETNEQDGFAHAMDTVL 264 +G AM NA ++KA A +T +N +DG AH +++++ Sbjct: 237 VEYAGTGIAMSNAVPELKAAANSITLSNNEDGIAHVLNSLI 277 >VC1364 [R] COG0561 Predicted hydrolases of the HAD superfamily Vch Vibrio cholerae Length = 273 Score = 92.8 bits (229), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 73/264 (27%), Positives = 119/264 (45%), Gaps = 12/264 (4%) Query: 6 LVVSDVDGTLLTKDKTLTDGARAAVRRLHEAGIGFTIVSSRPTIGMGFLIAPLAITQP-- 63 L+ D+DGTLL K ++ + A+ + + GI + S RP GM + L +T Sbjct: 4 LIALDMDGTLLNSQKQISPRTKQAIAQARQQGIQVVLASGRPLDGMRSKLEELHLTTEND 63 Query: 64 -IGAFNGSSIVDPQL-KPLEQHLIPAAVAKRCIDMLHERGVDIWLFTNDRWLTRNPDGEY 121 + +NGS + + + + Q +I AKR + E G++ F+ L +Y Sbjct: 64 YVLYYNGSMVANVGTGEIIHQQIIDGKAAKRVATLAQEFGLNTHAFSQIHGLITPKTSQY 123 Query: 122 TAHEQHTIKHDPTIVSDFTPYLDQ----ACKIVGASSDAALLRRGEVEMQQMVGRDATAV 177 T E +I DF D IVG L + ++ + T V Sbjct: 124 TEVEA-SINGLNITEMDFAQLADDHPIIKAMIVGEPEK---LTQAIAQLPAQWREEFTVV 179 Query: 178 RSQTYYLDVTPPGHDKGTFVEGIAKRLGVPLENVATIGDMQNDLPMFARSGVSFAMGNAS 237 +S ++L+ G +KG V+ IA LG+ V +GD +ND M +G+ AM NA Sbjct: 180 QSAPFFLEFLNTGSNKGIGVQAIAAHLGIQASEVICMGDAENDHHMLQYAGLGIAMANAM 239 Query: 238 DDVKARATHVTETNEQDGFAHAMD 261 ++ K A H+T +N+ DG A A++ Sbjct: 240 EETKHIADHITLSNDHDGVAVAIE 263