BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0138.0010.p (410 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc1918 [GEPR] COG0477 Permeases of the major facilitator superf... 226 1e-58 SMc02603 [GEPR] COG0477 Permeases of the major facilitator super... 223 7e-58 PA1286 [GEPR] COG0477 Permeases of the major facilitator superfa... 211 2e-54 NMA0047 [GEPR] COG0477 Permeases of the major facilitator superf... 171 3e-42 AGl3235 [GEPR] COG0477 Permeases of the major facilitator superf... 102 1e-21 >AGc1918 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 414 Score = 226 bits (575), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 149/405 (36%), Positives = 222/405 (54%), Gaps = 6/405 (1%) Query: 5 QVLRPTLPILIGA--SIMLTLSMGLRQSLGIFMQPLTHDIGISISHFTLALAVQNLAWGF 62 Q R T+P LI A S++ ++ G R ++G F P+ D G S F LA+A+QNL WG Sbjct: 13 QATRQTMPWLIIAAGSLIAVMTFGPRSAMGFFQLPMLADTGWDRSTFGLAMALQNLFWGL 72 Query: 63 LQPVAGAMTVRYGFRPIMVVGALAYIAGLVLMTTAHGLVAIMIGAGVLIGLSLACTANAI 122 QP GA+ +YG ++V+ + Y AGLV M+ + G GVL+GL +A + ++ Sbjct: 73 GQPFFGAIADKYGTGRVLVLSGILYAAGLVCMSFGTSPFWLHFGGGVLVGLGIAAGSFSV 132 Query: 123 AMSVSARAVPETVRSTVLGMVSAAGSLGALLSAPIGQMLNEGFGWRVGLAGFVILSIFMI 182 +S AR V RS G+ +AAGS G L API Q L +GW L V L+ M+ Sbjct: 133 ILSAFARHVTPQQRSLAFGIGTAAGSAGMFLFAPISQGLISAYGWSDSL---VWLAAMMV 189 Query: 183 PAALYAGRVDKIPLPKPAADDIGNATAATAAKTAFGNAAFVVMTCAYMVCGMQLVFLTTH 242 L A + + T A K A G+ +++++T + VCG Q+ F+T H Sbjct: 190 LVPLLAWPMRGNSSSGSQSQAQFQQTVGEALKEALGHKSYLLLTTGFFVCGFQVAFITAH 249 Query: 243 LPSYLAICGLDPMLSAQTLGMIGGFNVLGSLFFGWAGQRWNKLALLGAIYILRSLALAWY 302 P+YL G++P + + +IG FN++GSL G QR++K LL IYI RS+ + + Sbjct: 250 FPAYLGDIGIEPRYAVIAMALIGFFNIIGSLAAGVIAQRYSKPYLLAYIYIARSVVVTAF 309 Query: 303 FMLPATPGSTLLFGAIMGFLWMGVGPLVAGAVAEMFGLRWQAMIQGLAFMSHQVGSFLGA 362 +LP +P S +LF + MG LW+ P VA MFG R M+ G+ F++HQ+GSFLG Sbjct: 310 LLLPQSPLSVILFASFMGILWLSTVPPTNALVAIMFGTRHLGMLGGVVFLTHQIGSFLGV 369 Query: 363 YGGGLIYDSLGSYTMAWRIGVALGLAGGIIQVAFALIRPAQPPLL 407 + GG +YD G+Y + W +GV +G+ I+ RPA P++ Sbjct: 370 WLGGFLYDRFGTYDIVWWLGVGMGIFAAIVHWPIQE-RPAPRPVM 413 >SMc02603 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 412 Score = 223 bits (568), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 148/407 (36%), Positives = 221/407 (54%), Gaps = 18/407 (4%) Query: 6 VLRPTLP--ILIGASIMLTLSMGLRQSLGIFMQPLTHDIGISISHFTLALAVQNLAWGFL 63 V R LP I++ SI+ L+ G R ++G F P+ + G + F LA+A QNL WG Sbjct: 12 VERSGLPWLIIVAGSIIAMLTFGPRSAMGFFQLPMLAEKGWDRTTFGLAMAFQNLCWGLG 71 Query: 64 QPVAGAMTVRYGFRPIMVVGALAYIAGLVLMTTAHGLVAIMIGAGVLIGLSLACTANAIA 123 QP GA+ ++G ++ + L Y AGL+LM A + + IG GVL+GL +A + I Sbjct: 72 QPFFGAIADKFGTWRVLALSGLVYAAGLILMAFADAPIWLHIGGGVLVGLGVASGSFGIV 131 Query: 124 MSVSARAVPETVRSTVLGMVSAAGSLGALLSAPIGQMLNEGFGWRVGLAGFVILSIFMIP 183 +S AR V RS G+ +AAGS G L AP+ Q L +GW S+ + Sbjct: 132 LSAFARNVAPEQRSLAFGIGTAAGSAGMFLFAPLSQGLISAYGWSD--------SLVYLG 183 Query: 184 AALYAGRVDKIPLPKPAA-----DDIGNATAATAAKTAFGNAAFVVMTCAYMVCGMQLVF 238 + + IPL A+ + + T A K A G+ +++++ + VCG Q+ F Sbjct: 184 LLMLLVPLFAIPLRGNASSGRQSEALFKQTVGEALKEALGHKSYLLLVSGFFVCGYQVAF 243 Query: 239 LTTHLPSYLAICGLDPMLSAQTLGMIGGFNVLGSLFFGWAGQRWNKLALLGAIYILRSLA 298 +T H P+Y+ G+D + L +IG FN++GS G GQR++K L IY+ RS+ Sbjct: 244 ITAHFPAYIGDIGIDARYAVIALALIGFFNIIGSFSAGIIGQRYSKPYFLALIYLARSVV 303 Query: 299 LAWYFMLPATPGSTLLFGAIMGFLWMGVGPLVAGAVAEMFGLRWQAMIQGLAFMSHQVGS 358 ++ + +LP TP S ++F +MG LW+ P G VA MFG R ++ G+ F+SHQ+GS Sbjct: 304 VSAFLLLPQTPTSVIVFAVVMGLLWLSTVPPTNGLVAIMFGTRHLGLLGGIVFLSHQIGS 363 Query: 359 FLGAYGGGLIYDSLGSYTMAWRIGVALGLAGGIIQ---VAFALIRPA 402 FLG + GG +YD GSY W +GVALG+ I+ A+ RPA Sbjct: 364 FLGVWMGGYLYDHFGSYDPVWWVGVALGVFAAIVHWPIEERAVARPA 410 >PA1286 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 399 Score = 211 bits (537), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 136/373 (36%), Positives = 203/373 (54%), Gaps = 7/373 (1%) Query: 8 RPTLPILIGASIMLTLSMGLRQSLGIFMQPLTHDIGISISHFTLALAVQNLAWGFLQPVA 67 R IL+ +++L LS+G+R G+F+ P++ D G F A+A+QNL WG QP Sbjct: 3 RAAFWILLSGALILALSLGVRHGFGLFLAPMSADFGWGREVFAFAIALQNLVWGLAQPFT 62 Query: 68 GAMTVRYGFRPIMVVGALAYIAGLVLMTTAHGLVAIMIGAGVLIGLSLACTANAIAMSVS 127 GA+ RYG ++VG L Y GLVLM + + + AG+LIGL L+ T+ ++ + Sbjct: 63 GALADRYGAARAVLVGGLLYALGLVLMGLSQSASGLSLSAGLLIGLGLSGTSFSVILGAV 122 Query: 128 ARAVPETVRSTVLGMVSAAGSLGALLSAPIGQMLNEGFGWRVGLAGFVILSIFMIPAALY 187 RAVP RS +G+ SAAGS G P L GW L +L ++P Sbjct: 123 GRAVPAEQRSMAMGISSAAGSFGQFAMLPGTLGLIGWLGWSSALLALGLLVALIVP---L 179 Query: 188 AGRVDKIPLPKPAADDIGNATAATAAKTAFGNAAFVVMTCAYMVCGMQLVFLTTHLPSYL 247 AG + PLP + + A + A ++ F ++ + VCG Q+VF+ HLP+YL Sbjct: 180 AGLMKDRPLPPQGHEQ----SLGEALREACAHSGFWLLALGFFVCGFQVVFIGVHLPAYL 235 Query: 248 AICGLDPMLSAQTLGMIGGFNVLGSLFFGWAGQRWNKLALLGAIYILRSLALAWYFMLPA 307 L + L ++G FNV G+ GW G RW+K LL A+Y++R + + + LP Sbjct: 236 VDQHLPAQVGTTVLALVGLFNVFGTYIAGWLGGRWSKPRLLTALYLVRGVVIVLFLWLPL 295 Query: 308 TPGSTLLFGAIMGFLWMGVGPLVAGAVAEMFGLRWQAMIQGLAFMSHQVGSFLGAYGGGL 367 + S FG MG LW+ PL G VA +FG+R +M+ G+ F+ HQ+G+FLG + GG+ Sbjct: 296 SVYSAYAFGVAMGLLWLSTVPLTNGTVATLFGVRNLSMLGGIVFLFHQLGAFLGGWLGGV 355 Query: 368 IYDSLGSYTMAWR 380 +YD GSY + W+ Sbjct: 356 VYDRTGSYDLVWQ 368 >NMA0047 [GEPR] COG0477 Permeases of the major facilitator superfamily NmA Neisseria meningitidis Z2491 Length = 405 Score = 171 bits (433), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 109/366 (29%), Positives = 188/366 (51%), Gaps = 5/366 (1%) Query: 17 ASIMLTLSMGLRQSLGIFMQPLTHDIGISISHFTLALAVQNLAWGFLQPVAGAMTVRYGF 76 A+ +L +++G+R +LG+F+QP+ + +SI+ F+L +AV L WG QP++GA+ R+G Sbjct: 18 AAFILLITIGMRMTLGLFVQPVVNTTELSIAQFSLIIAVFQLMWGVSQPLSGALADRFGA 77 Query: 77 RPIMVVGALAYIAGLVLMTTAHGLVAIMIGAGVLIGLSLACTANAIAMSVSARAVPETVR 136 ++ GA+ + ++ +MI G+L+ +I M A VP R Sbjct: 78 FRVLSGGAVLLVCACLIAPNIPTYWGLMIAVGLLLAFGTGSGGFSIIMGQVAAQVPAHKR 137 Query: 137 STVLGMVSAAGSLGALLSAPIGQ---MLNEGFGWRVGLAGFVILSIFMIPAALYAGRVDK 193 G+V+A GS G L AP+ Q +L E GW + +++ +P + + + Sbjct: 138 GLASGLVNAGGSAGQFLFAPLVQGLVVLPE-VGWTGTFYVWGAIALLTLPVSWWLAGGNN 196 Query: 194 IPLPKPAADDIGNATAATAAKTAFGNAAFVVMTCAYMVCGMQLVFLTTHLPSYLAICGLD 253 + A G + A KTAF +++++ ++ CG + FL THLP+ +A+CGL Sbjct: 197 AAHTQHAQATHGQSLGE-AVKTAFKTPSYILLHLSFFACGFHIAFLVTHLPTEVALCGLP 255 Query: 254 PMLSAQTLGMIGGFNVLGSLFFGWAGQRWNKLALLGAIYILRSLALAWYFMLPATPGSTL 313 +++ ++ +IG N+ G +F GW R +L +Y R+ + Y P T + Sbjct: 256 ATVASTSIAIIGLANIAGCIFSGWCTSRVRGKYVLFGLYASRAAMILIYIFSPKTDLNFY 315 Query: 314 LFGAIMGFLWMGVGPLVAGAVAEMFGLRWQAMIQGLAFMSHQVGSFLGAYGGGLIYDSLG 373 +F A +GF W+ A ++FG R+ A + GL +SHQ+G FLG+Y GG++ G Sbjct: 316 IFAAALGFTWLATVTPTASITGKLFGTRYLATLFGLTMLSHQIGGFLGSYIGGIVITQFG 375 Query: 374 SYTMAW 379 Y W Sbjct: 376 DYGWMW 381 >AGl3235 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 433 Score = 102 bits (255), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 103/351 (29%), Positives = 160/351 (45%), Gaps = 34/351 (9%) Query: 30 SLGIFMQPLTHDIGISISHFTLALAVQNLAWGFLQPVAGAMTVRYGFRPIMVVGALAYIA 89 S G+ +QPL + G I+ + A+AV+ + +G L P A A +G R + V ALA I Sbjct: 40 SAGVMIQPLHQEFGWDIADISSAMAVRLVLFGLLGPFAAAFMNHFGIRQV-VSTALALIM 98 Query: 90 GLVL----MTTAHGLVAIMIGAGVLIGLSLACTANAIAMSVSARAVPETVRSTVLGMVSA 145 G ++ MT L+ + GV+IG+ TA + +V++R + R V+G+++A Sbjct: 99 GGIVASFFMTQVWQLLLLW---GVVIGVGTGMTALVLGATVASRWFSKR-RGLVIGLMTA 154 Query: 146 AGSLGALLSAPIGQMLNEGFGWRVGLAGFVILSIFMIPAA------LYAGRVDKIPLP-- 197 + + G L+ P+ L E +GWR L LS+ +I AA L + LP Sbjct: 155 SNATGQLVFLPLLAALTEAYGWRTALT----LSVAVIAAAMILVLLLMRDHPSDVGLPAY 210 Query: 198 ------KPAADDIGNATAATAA-----KTAFGNAAFVVMTCAYMVCGMQLV-FLTTHLPS 245 KP D N A A+ K+ GN F V+ + VCG+ + TH S Sbjct: 211 GETAVSKPPKQD-HNLLATLASPLVTLKSVSGNPVFWVLFGTFFVCGLSTNGLIQTHWIS 269 Query: 246 YLAICGLDPMLSAQTLGMIGGFNVLGSLFFGWAGQRWNKLALLGAIYILRSLALAWYFML 305 G+ + +A TL +IG F+ G++F GW R++ LL Y LR L+L + Sbjct: 270 ICGDFGMAAVTAAGTLAVIGIFDFFGTIFAGWLSDRFDNRFLLFWFYGLRGLSLIYLSFS 329 Query: 306 PATPGSTLLFGAIMGFLWMGVGPLVAGAVAEMFGLRWQAMIQGLAFMSHQV 356 + +F G W+ P AE FG ++ G F HQ+ Sbjct: 330 GFSFVELSVFAVFYGLDWVATVPPTVKLAAENFGREKAGLVFGWVFAGHQL 380