BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0137.0056.p (505 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll5686 [GEPR] COG0477 Permeases of the major facilitator superf... 739 0.0 AGl1729 [GEPR] COG0477 Permeases of the major facilitator superf... 656 0.0 RSc2323 [GEPR] COG0477 Permeases of the major facilitator superf... 535 e-152 mll2542 [GEPR] COG0477 Permeases of the major facilitator superf... 168 3e-41 CAC0020_1 [GEPR] COG0477 Permeases of the major facilitator supe... 163 1e-39 >mll5686 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 502 Score = 739 bits (1908), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/497 (79%), Positives = 436/497 (87%), Gaps = 2/497 (0%) Query: 1 MSTELSRRGAVVLSAICLACLMFGLEISSIPAILPTLERVLHADFKALQWIMNAYTIAVT 60 M T L+RRG VVLSA CLACLMFGLEISS+P ILPTLE+ LHADF+ LQW+MNAYTIAVT Sbjct: 1 MPTALTRRGIVVLSAACLACLMFGLEISSVPTILPTLEQELHADFRQLQWVMNAYTIAVT 60 Query: 61 TVLMAIGTVADRYGRKRIFLVAIAAFGVTSLICGVASSVEMLIVARFLQGLSGGALLICQ 120 TVLMA+GT+ADRYGRKR+FL++IAAFG+TSLICG+A V LIVARFLQGLSGGA+LICQ Sbjct: 61 TVLMAVGTIADRYGRKRVFLISIAAFGLTSLICGLADDVSTLIVARFLQGLSGGAVLICQ 120 Query: 121 IAVLSHEFQGGRVRAVAWGWWGVIFGIGLGFGPIIGGAVVAALSWEWVFLVHVLFAAVAF 180 +AVLSHEF+ GR RAVAWGWWGVIFG+GLGFGPIIGG +VAA SWEWVFL+H AAVAF Sbjct: 121 LAVLSHEFREGRERAVAWGWWGVIFGVGLGFGPIIGGGIVAASSWEWVFLIHGPAAAVAF 180 Query: 181 VLTIGGVHESKDPKASSLDVAGIVTMSLAVFCLAFYITQGPDLGFVSPKGLAILGVSAGS 240 VL GVHESKDP+A LD+AGIVT+S +VFCL FYITQGPDLGF SP L ILGVS S Sbjct: 181 VLAWTGVHESKDPEAGKLDLAGIVTLSPSVFCLVFYITQGPDLGFASPVALTILGVSIAS 240 Query: 241 FIAFLVAEKISRRPMFDFSVFRIPAFSGSIVGSAAMNLSYWPFMIYLPIWFHAGLGYDSV 300 FIAFL+AE+IS+RPMFDFSVFRI FSG+IVGSAAMNLSYWPFMIYLPIWFHAGLGYDS+ Sbjct: 241 FIAFLIAERISKRPMFDFSVFRIRPFSGAIVGSAAMNLSYWPFMIYLPIWFHAGLGYDSI 300 Query: 301 SAGLALLAYTLPTLVMPPFAERLSLRYQPGLIIPVGLFTIGAGFMLMKFGSAAAQPDWVT 360 S GLALLAYTLPTLVMPP AERLSLRYQPG+IIP GL IG GF+LMKFGSAAA+PDW+T Sbjct: 301 STGLALLAYTLPTLVMPPLAERLSLRYQPGIIIPAGLAVIGVGFILMKFGSAAARPDWLT 360 Query: 361 MLPGCLLAGIGLGITNTPVTNTTTGSVSSDRAGMASGIDMSARMVSLSVNIALMGFILAS 420 MLPGCL+AG GLGITNTPVTNTTTGSVSSDRAGMASGIDMSARMVSL+VNIA+MGFILA Sbjct: 361 MLPGCLIAGAGLGITNTPVTNTTTGSVSSDRAGMASGIDMSARMVSLAVNIAVMGFILAG 420 Query: 421 GVLAHLKAVLPALDGAQLRAIAERIAAGDIASAPELTGPVVHQALASGFGWVMLYGGIGV 480 GVLAHL LP LD +QLR A+ IAAG+ +P L VVH AL +GFGWVMLYGGIGV Sbjct: 421 GVLAHLSTALPDLDASQLRLFADGIAAGN--PSPRLADSVVHNALRNGFGWVMLYGGIGV 478 Query: 481 WIMAALSFLIFNAPPVR 497 WIMAA+SF+ FNA V+ Sbjct: 479 WIMAAISFVSFNARRVQ 495 >AGl1729 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 506 Score = 656 bits (1692), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/493 (67%), Positives = 411/493 (83%), Gaps = 2/493 (0%) Query: 1 MSTELSRRGAVVLSAICLACLMFGLEISSIPAILPTLERVLHADFKALQWIMNAYTIAVT 60 ++ + R A+ L+A+CL+ LMFGLEISS+PAILPTLE VL ADF+ LQWIMNAYTI VT Sbjct: 5 VTEQAGSRSAMALAAVCLSALMFGLEISSVPAILPTLEEVLQADFRQLQWIMNAYTIGVT 64 Query: 61 TVLMAIGTVADRYGRKRIFLVAIAAFGVTSLICGVASSVEMLIVARFLQGLSGGALLICQ 120 VLMA G +ADR+GRKR+F+ +I AF ++SL CG+ SV +LI ARFLQGLSGGA+L+CQ Sbjct: 65 MVLMATGALADRFGRKRVFIASIVAFALSSLACGMTQSVSVLIGARFLQGLSGGAMLVCQ 124 Query: 121 IAVLSHEFQGGRVRAVAWGWWGVIFGIGLGFGPIIGGAVVAALSWEWVFLVHVLFAAVAF 180 IA+LSH+F+ R R +A+GWWG++ G+GLGFGPIIGGA+VA SWEWVFLVHV+ V + Sbjct: 125 IAILSHQFRTARERGMAFGWWGIVSGVGLGFGPIIGGAIVALWSWEWVFLVHVVLGIVTW 184 Query: 181 VLTIGGVHESKDPKASSLDVAGIVTMSLAVFCLAFYITQGPDLGFVSPKGLAILGVSAGS 240 +L GGV ES+DP+A+ LD+AG+ T+S+AVFCLAF+ITQGP+LGF +P L ILG+S S Sbjct: 185 LLAAGGVGESRDPEAARLDLAGMATLSVAVFCLAFFITQGPELGFANPMALLILGISVAS 244 Query: 241 FIAFLVAEKISRRPMFDFSVFRIPAFSGSIVGSAAMNLSYWPFMIYLPIWFHAGLGYDSV 300 FIAF++AEK ++RPMFDFSVFRI FSG+I+GSAAMN+S+WPFMIYLPIWF AGLGYDSV Sbjct: 245 FIAFVIAEKRTQRPMFDFSVFRIRPFSGAIIGSAAMNISFWPFMIYLPIWFQAGLGYDSV 304 Query: 301 SAGLALLAYTLPTLVMPPFAERLSLRYQPGLIIPVGLFTIGAGFMLMKFGSAAAQPDWVT 360 +AGL LLAYTLP LVMPP AERLSLRYQP L+IP GLFTIG GFMLMKFGS W+T Sbjct: 305 TAGLGLLAYTLPALVMPPLAERLSLRYQPHLVIPAGLFTIGLGFMLMKFGSGIENASWLT 364 Query: 361 MLPGCLLAGIGLGITNTPVTNTTTGSVSSDRAGMASGIDMSARMVSLSVNIALMGFILAS 420 MLPGC+LAGIGLG+TNTPVTNTTTG+VS R+GMASGIDMSARM+SL++NI +MGFIL Sbjct: 365 MLPGCILAGIGLGLTNTPVTNTTTGAVSPARSGMASGIDMSARMISLAINIPIMGFILVE 424 Query: 421 GVLAHLKAVLP-ALDGAQLRAIAERIAAGDIASAP-ELTGPVVHQALASGFGWVMLYGGI 478 GV A L+A LP + L+++AE+IAAG +++ P E++ +VH+ALA GFG VM+Y GI Sbjct: 425 GVRASLRANLPVGTEMKALQSLAEKIAAGTVSTLPQEVSERLVHRALADGFGLVMVYAGI 484 Query: 479 GVWIMAALSFLIF 491 GVW++AALS+L+F Sbjct: 485 GVWLLAALSYLVF 497 >RSc2323 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 521 Score = 535 bits (1379), Expect = e-152, Method: Compositional matrix adjust. Identities = 296/489 (60%), Positives = 364/489 (74%), Gaps = 13/489 (2%) Query: 22 MFGLEISSIPAILPTLERVLHADFKALQWIMNAYTIAVTTVLMAIGTVADRYGRKRIFLV 81 MFGLEISS+P ILPTLE LH DF +QWIMNAYTIA T VLMA GT+ADRYGRKR+FL Sbjct: 35 MFGLEISSVPVILPTLEVALHGDFSGIQWIMNAYTIACTAVLMATGTLADRYGRKRVFLY 94 Query: 82 AIAAFGVTSLICGVASSVEMLIVARFLQGLSGGALLICQIAVLSHEFQGGRVRAVAWGWW 141 IA FGV SL+CG+A + +LI +RFLQG SGGA+LIC +AVLSH+F G R A+G W Sbjct: 95 TIALFGVASLLCGLAWNTPILIASRFLQGASGGAMLICLVAVLSHQFPEGAERGKAFGIW 154 Query: 142 GVIFGIGLGFGPIIGGAVVAALSWEWVFLVHVLFAAVAFVLTIGGVHESKDPKASSLDVA 201 G++FGIGLGFGP+IGG +VA W+WVF VHV AA+ F L I GV ES+DP A LD+A Sbjct: 155 GIVFGIGLGFGPLIGGLIVAMSGWKWVFWVHVFIAALTFGLAIVGVRESRDPHARRLDLA 214 Query: 202 GIVTMSLAVFCLAFYITQGPDLGFVSPKGLAILGVSAGSFIAFLVAEKISRRPMFDFSVF 261 GIVT+SL V LA+++TQG D GF S L ++ +A SF FL+ E + PMFDFSVF Sbjct: 215 GIVTLSLTVLGLAYFVTQGADTGFGSASALRVIAATAVSFALFLIVEMRAAHPMFDFSVF 274 Query: 262 RIPAFSGSIVGSAAMNLSYWPFMIYLPIWFHAGLGYDSVSAGLALLAYTLPTLVMPPFAE 321 R+ FSG+++GS MN S+WPF+IYLPI+F + LG + +AG++LLAYTLPTLV PP E Sbjct: 275 RVRNFSGALLGSVGMNFSFWPFIIYLPIYFQSALGQGAAAAGVSLLAYTLPTLVFPPIGE 334 Query: 322 RLSLRYQPGLIIPVGLFTIGAGFMLMKFGSAAAQPDWVTMLPGCLLAGIGLGITNTPVTN 381 RL+LRY+PG++IP GLFTIG GF LM GS+ Q W+T+LPGCLLAG GLGITNTPVTN Sbjct: 335 RLALRYRPGIVIPAGLFTIGLGFFLMLIGSSIDQASWLTVLPGCLLAGAGLGITNTPVTN 394 Query: 382 TTTGSVSSDRAGMASGIDMSARMVSLSVNIALMGFILASGVLAHLK-AVLPALDGAQLRA 440 TTTGSVS RAGMASGIDMSARM+SL++NIALMGF+L VL +L+ A++ D A RA Sbjct: 395 TTTGSVSPARAGMASGIDMSARMISLAINIALMGFLLMQRVLQYLQIALVKPADEASWRA 454 Query: 441 IAERIAAGDIASA---------PELTGPVVHQALASGFGWVMLYGGIGVWIMAALSFLIF 491 +A RIA+G++ +A PE + AL GFG VMLY GI VW++AA SFLIF Sbjct: 455 LASRIASGNLHAADATAWAPMSPETLETIGRAALVHGFGGVMLYSGIAVWVLAAASFLIF 514 Query: 492 NAPPVRQAE 500 + R+A+ Sbjct: 515 SG---RKAQ 520 >mll2542 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 505 Score = 168 bits (426), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 117/412 (28%), Positives = 205/412 (49%), Gaps = 10/412 (2%) Query: 12 VLSAICLACLMFGLEISSIPAILPTLERVLHADFKALQWIMNAYTIAVTTVLMAIGTVAD 71 +++A+ L + L++S + LPT+++ LH DF LQW+++AYT+ ++ +++ G + D Sbjct: 8 LVAAVYLGTFVALLDVSIVNVALPTIQQALHTDFGGLQWVVDAYTLCLSAFMLSSGLIGD 67 Query: 72 RYGRKRIFLVAIAAFGVTSLICGVASSVEMLIVARFLQGLSGGALLICQIAVLSHEFQGG 131 RYGRKR +L + F SLIC VA ++ L+ R +QG++G L+ +++L+ F Sbjct: 68 RYGRKRSWLAGVGIFVAGSLICAVAPNLPALLAGRVVQGIAGSLLIPGALSILTQAFPDP 127 Query: 132 RVRAVAWGWWGVIFGIGLGFGPIIGGAVVAALSWEWVFLVHVLFAAVAFVLTIGGVHESK 191 R RA G W + L GP++GG +V + W+ +FL+++ VL + E+ Sbjct: 128 RERAGVIGGWAAFAAVSLVVGPVLGGILVQTVGWQSIFLINLPLGLFTIVLGAVSIEETS 187 Query: 192 DPKASSLDVAGIVTMSLAVFCLAFYITQGPDLGFVSPKGLAILGVSAGSFIAFLVAEKIS 251 P+ + LD+ G+ L + L F + + G+ P+ + + V FL E + Sbjct: 188 HPEHAHLDLVGLALSILWLGALTFGLISAGESGWGDPRTIVAIIVGVVGLAVFLGFEART 247 Query: 252 RRPMFDFSVFRIPAFSGSIVGSAAMNLSYWPFMIYLPIWFHAGLGYDSVSAGLALLAYTL 311 RPM +FR F+ + V S A+ + + + + ++ G+ GL + L Sbjct: 248 PRPMLPLGLFRDVRFAVANVASFALGFTSYSCVFFFSMFLQQVQGWSPTQTGLRMAPAFL 307 Query: 312 PTLVMPPFAERLSLRYQPGLIIPVGLFTIGAGFMLMKFGSAAAQPDWVTMLPGCLLAGIG 371 +V+ P+ RLS RY L++ G IG L G A P L L G Sbjct: 308 VQIVVSPWIGRLSARYGHSLLMTAGYVLIG----LSMLGMCWAGPSTPYALLCVLFTING 363 Query: 372 LGITNTPVTNTTTGSVSS----DRAGMASGIDMSARMVSLSVNIALMGFILA 419 LG N+ T + + S +R+GM S + + R L++ IAL+G +++ Sbjct: 364 LG--NSLAIPTGSAAAMSYAPRERSGMVSAVINATRQSGLAIGIALLGALMS 413 >CAC0020_1 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 458 Score = 163 bits (412), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 104/390 (26%), Positives = 199/390 (51%), Gaps = 5/390 (1%) Query: 34 LPTLERVLHADFKALQWIMNAYTIAVTTVLMAIGTVADRYGRKRIFLVAIAAFGVTSLIC 93 LP + WI Y +A+ ++ AD++GRK++ ++ I FGV+S +C Sbjct: 31 LPNITDYFKVSLNDTSWISTIYALALAVFMITAAKFADQFGRKKLMIIGILIFGVSSALC 90 Query: 94 GVASSVEMLIVARFLQGLSGGALLICQIAVLSHEFQGGRVRAVAWGWWGVIFGIGLGFGP 153 G+++S+ LI+ RF+QG+ GGA++ + E G + G G + G+ GP Sbjct: 91 GISNSLLFLIIMRFVQGI-GGAIITPIALPMGIEIFGKERMNIVVGASGAVVGLAAASGP 149 Query: 154 IIGGAVVAALSWEWVFLVHVLFAAVAFVLTIGGVHESKDPKAS-SLDVAGIVTMSLAVFC 212 +GG ++ ++W+ VF V+V FA A +L + V+ES D S +D G++T+++++FC Sbjct: 150 PLGGVLIKYINWQSVFFVNVPFAIAALILIVICVNESYDNTVSKDIDWFGVMTLTISLFC 209 Query: 213 LAFYITQGPDLGFVSPKGLAILGVSAGSFIAFLVAEKISRRPMFDFSVFRIPAFSGSIVG 272 L F + +G D G+ S +++ + S I F++ E PM + ++F+ P F+ S + Sbjct: 210 LIFALLKGKDYGWTSTLIISLFLIFVVSLILFIIIELKVSSPMIEINLFKEPTFTASSIC 269 Query: 273 SAAMNLSYWPFMIYLPIWFHAGLGYDSVSAGLALLAYTLPTLVMPPFAERLSLRYQPGLI 332 ++ L + L YD++ A +++ +L + P L + P +I Sbjct: 270 YMITGFGLMCPLLILNYYLQNVLQYDTLEAAFIMMSVSLTGMFSTPIGSILGKKVSPRII 329 Query: 333 IPVGLFTIGAGFMLMKFGSAAAQPDWVTMLPGCLLAGIGLGITNTPVTNTTTGSVSSDRA 392 +G+ ++G G + + S TM+ ++ GIGLG + +++ + +++ Sbjct: 330 NFIGMLSLGIGIFRLSYLSYGMSKG--TMIFDLIICGIGLGFS-VQALSSSVKFIPKEKS 386 Query: 393 GMASGIDMSARMVSLSVNIALMGFILASGV 422 G+ SGI +AR + + IA++ +L S V Sbjct: 387 GIGSGIVNAARQIGSCIGIAILVSMLNSNV 416