BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0137.0044.p (405 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb20272 [GEPR] COG0477 Permeases of the major facilitator super... 590 e-168 mlr2429 [GEPR] COG0477 Permeases of the major facilitator superf... 381 e-105 mll1685 [GEPR] COG0477 Permeases of the major facilitator superf... 132 2e-30 AF0367 [GEPR] COG0477 Permeases of the major facilitator superfa... 107 4e-23 AGl3235 [GEPR] COG0477 Permeases of the major facilitator superf... 97 5e-20 >SMb20272 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 402 Score = 590 bits (1521), Expect = e-168, Method: Compositional matrix adjust. Identities = 298/398 (74%), Positives = 347/398 (87%), Gaps = 1/398 (0%) Query: 1 MSNSTYRWVIVAAGGLLGCVAIGGMFSLPVFLQPMARETGWSVTGISSAMTIGFLAMAFT 60 M ++ YRWVIVAAGGLLGC+AIG MFSLPVFL P++R+TGWSVTGISSAMT+GF+AMA Sbjct: 1 MIDAHYRWVIVAAGGLLGCIAIGAMFSLPVFLVPISRDTGWSVTGISSAMTVGFIAMALA 60 Query: 61 SMIWGTLSDRFGPLPVVLTGSVVLAASLALASQVTSLLAFQFVFGALVGAATAAIFAPMM 120 SM+WG+ SDR+GP VVL GS +LAASLAL+S VTSL+AFQ VFG +VG A AAIFAPMM Sbjct: 61 SMVWGSASDRWGPRSVVLIGSALLAASLALSSLVTSLIAFQLVFGVVVGGACAAIFAPMM 120 Query: 121 ACVTGWFDTHRSLAVSLVSAGMGMAPMTMSPLAAWLISHHDWRTAMLIVSGVVGAIMIPV 180 ACVTGWFDTHRSLAVSLVSAGMGMAPMTMSPLA WL++ +DWRT++ I++ + MIP Sbjct: 121 ACVTGWFDTHRSLAVSLVSAGMGMAPMTMSPLAGWLVTIYDWRTSLQIIAALAAVTMIPA 180 Query: 181 SFLVRRPPALQGDHAEAVSENGEPPMSLAQALRSPQFIILIATNFFCCATHSGPIIHTVS 240 + L+RRPP L+ +A + SE G+P MSL QALRSPQF+IL+ TNFFCCATHSGPI HTVS Sbjct: 181 ALLLRRPPVLEDTNAVSASE-GQPDMSLGQALRSPQFVILLLTNFFCCATHSGPIFHTVS 239 Query: 241 YAVTCGIPMVAAVTIYSVEGLAGMGGRIAFGLLGDRFGAKRVLVLGLLAQAFGALGYVFV 300 YAV+CGIPM+AAV+IYS+EGLAGMGGR+AFG+LGDR+GAKR+LV GLL QAFGAL Y FV Sbjct: 240 YAVSCGIPMMAAVSIYSLEGLAGMGGRVAFGVLGDRYGAKRILVSGLLLQAFGALAYFFV 299 Query: 301 RELAAFYAVAAIFGFIYAGTMPLYSVLIRENFPLRMMGTVIGGTAMAGSLGMATGPLAGG 360 R+L AFYAVAA+FGFIYAG MPLY+V+ RENFPLRMMGTVIGGTAMAGSLGMA GP+AGG Sbjct: 300 RDLGAFYAVAAVFGFIYAGVMPLYAVIARENFPLRMMGTVIGGTAMAGSLGMAIGPVAGG 359 Query: 361 LIYDTFASYTWLYVGSWAVGIGAFLIMMTFRPMPAVRP 398 LIYD FASY WLY+G+W +GIGAFLI +TF+P P RP Sbjct: 360 LIYDVFASYGWLYIGAWGLGIGAFLIALTFKPFPRERP 397 >mlr2429 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 400 Score = 381 bits (978), Expect = e-105, Method: Compositional matrix adjust. Identities = 222/394 (56%), Positives = 277/394 (70%), Gaps = 4/394 (1%) Query: 3 NSTYRWVIVAAGGLLGCVAIGGMFSLPVFLQPMARETGWSVTGISSAMTIGFLAMAFTSM 62 N +YRWVIVA G L+ CVAIG MFSL +FL+PMA +T WS GISSAMT+ FL M Sbjct: 2 NLSYRWVIVATGALMSCVAIGTMFSLAIFLEPMALDTQWSRAGISSAMTLNFLVMGLGGF 61 Query: 63 IWGTLSDRFGPLPVVLTGSVVLAASLALASQVTSLLAFQFVFGALVGAATAAIFAPMMAC 122 WG LSDRFG VV G+V+L +L +AS+ SLL FQ +G LVG A +A FAPM+A Sbjct: 62 AWGALSDRFGARIVVAIGAVLLGLALVVASRAGSLLTFQISYGVLVGLAASAFFAPMIAL 121 Query: 123 VTGWFDTHRSLAVSLVSAGMGMAPMTMSPLAAWLISHHDWRTAMLIVSGVVGAIMIPVSF 182 T WFDT+RSLAVSLVSAGMG+APMT+SP A WLIS ++WRTAM + + +++P Sbjct: 122 TTAWFDTNRSLAVSLVSAGMGVAPMTISPFARWLISAYEWRTAMFDIGIMAWVLLLPAVL 181 Query: 183 LVRRPP--ALQGDHAEAVSENGEPPMSLAQALRSPQFIILIATNFFCCATHSGPIIHTVS 240 LVR+PP A+ + V+E MS+AQALRSPQFI+L T F CCA HSGPI H VS Sbjct: 182 LVRQPPKPAVAAGASAPVAEGAG--MSVAQALRSPQFIVLGLTFFTCCAAHSGPIFHMVS 239 Query: 241 YAVTCGIPMVAAVTIYSVEGLAGMGGRIAFGLLGDRFGAKRVLVLGLLAQAFGALGYVFV 300 YA+ CG+ +AAVTIYSVEGLAG+GGR+ +G+L DR G K VL+ GL+ QA Y+ V Sbjct: 240 YAMLCGVAPMAAVTIYSVEGLAGLGGRLLYGVLADRLGVKPVLITGLVIQAVVIAAYLSV 299 Query: 301 RELAAFYAVAAIFGFIYAGTMPLYSVLIRENFPLRMMGTVIGGTAMAGSLGMATGPLAGG 360 +L FY +A IFG Y G MPLY+VL RE F R++GTV G M SLGMA GPLAGG Sbjct: 300 SQLDQFYVLAVIFGATYGGVMPLYAVLAREYFGQRILGTVFGAATMLSSLGMALGPLAGG 359 Query: 361 LIYDTFASYTWLYVGSWAVGIGAFLIMMTFRPMP 394 +++D +ASY WL++GS +G+GA I + F P+P Sbjct: 360 MVFDAYASYHWLFIGSALIGLGAAGIAIAFPPLP 393 >mll1685 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 469 Score = 132 bits (331), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 120/395 (30%), Positives = 184/395 (46%), Gaps = 10/395 (2%) Query: 3 NSTYRWVIVAAGGLLGCVAIGGMFSLPVFLQPMARETGWSVTGISSAMTIGFLAMAFTSM 62 +S+Y W+ +A +L + GM+++ V L + E G S T + A ++ Sbjct: 74 DSSYAWMRLAISMVLATIGAVGMWAVVVVLPAVQGEFGVDRAAASMPYTATMVGFAAGNV 133 Query: 63 IWGTLSDRFGPLPVVLTGSVVLAASLALASQVTSLLAFQFVFGALVGAATAAIFAPMMAC 122 + G DR G L SV L+A L LA+ TS+L F G L+G T+ IF P++A Sbjct: 134 LVGRAIDRMGYWIPALISSVALSAGLLLAALSTSILQFTLAQGVLIGVGTSVIFGPLIAD 193 Query: 123 VTGWFDTHRSLAVSLVSAGMGMAPMTMSPLAAWLISHHDWRTAMLIVSGVVGAIMIPVSF 182 ++ WF+ R +AV+ +AG +A + LI WR + M+P+ Sbjct: 194 ISHWFNRRRGVAVTAAAAGNYLAGALWPTIMPTLIKAEGWRFTYAAIGIFCLVTMVPLVL 253 Query: 183 LVRR-PPALQGDHAEAVSENGEPPMSLAQALRSPQFIILIATNFFCCATHSGPIIHTVSY 241 ++RR P D + PMS A A++ +L+ CC S P +H V+Y Sbjct: 254 MLRRGAPEATADGSPGSRSVQPIPMSPA-AMQG----LLVVAGLGCCVAMSMPQVHIVAY 308 Query: 242 AVTCGIPMVAAVTIYSVEGLAGMGGRIAFGLLGDRFGAKRVLVLGLLAQAFGALGYVFVR 301 + G M + S+ AG+ R+A G + DR G + L++G + Q L Y+ Sbjct: 309 CMDLGYGMAHGADMLSIMMAAGVVSRLASGFVADRIGGVKTLLIGSVLQCLSLLFYIPFD 368 Query: 302 ELAAFYAVAAIFGFIYAGTMPLYSVLIRENFPLRMMGTVIGGTAMAGSLGMATGPLAGGL 361 LA+ Y V+ +FG G +P Y++++RE P + G IG MA GMA G G Sbjct: 369 GLASLYVVSLVFGLSQGGIVPCYAIIVREYLPAKEAGQRIGIVMMATIFGMAIGGWMSGW 428 Query: 362 IYDTFASYTWLYVGSWA---VGIGAF-LIMMTFRP 392 IYD SY ++ A + IGA L M RP Sbjct: 429 IYDLTGSYAVAFLNGIAWNLLNIGAIGLFMWKARP 463 >AF0367 [GEPR] COG0477 Permeases of the major facilitator superfamily Afu Archaeoglobus fulgidus Length = 397 Score = 107 bits (268), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 98/372 (26%), Positives = 159/372 (42%), Gaps = 9/372 (2%) Query: 7 RWVIVAAGGLLGCVAIGGMFSLPVFLQPMARETGWSVTGISSAMTIGFLAMAFTSMIWGT 66 +W+++ AG LL + +G +++ VF+ P+ GWS T S +I L A + G Sbjct: 4 KWLVIFAGFLLNLM-LGIVYAWSVFVNPLMNTFGWSKTIASLPFSIFLLIFALMMVPAGR 62 Query: 67 LSDRFGPLPVVLTGSVVLAASLALASQVTSLLA---FQFVFGALVGAATAAIFAPMMACV 123 DR GP V + G V+L L+ + S+ + F +G + GA +A + Sbjct: 63 TQDRIGPRKVAMLGGVLLGVGFLLSGLIESIQSPYWLIFSYGVIAGAGCGLGYACPIPVA 122 Query: 124 TGWFDTHRSLAVSLVSAGMGMAPMTMSPLAAWLISHHDWRTAMLIVSGVVGAIMIPVSFL 183 WF LA LV G GM+ + +PL LI + T I+ ++ + + + L Sbjct: 123 RKWFPERVGLATGLVVMGFGMSALIFAPLERILIDTYGISTTFYILGVILLIVAVFAASL 182 Query: 184 VRRPPALQGDHAEAVSE----NGEPPMSLAQALRSPQFIILIATNFFCCATHSGPIIHTV 239 + PP L A ++ G+P + ++ LR +F +L + FF I H Sbjct: 183 LSNPPELPAVQASNPAKVEVVTGKPELGPSEMLRDYRFYVLWLSFFFMALAGLMVIGHIA 242 Query: 240 SYAVTCGIPMVAAVTIYSVEGLAGMGGRIAFGLLGDRFGAKRVLVLGLLAQAFGALGYVF 299 YA G+ +AA S+ +A GR G L D+ G + + L Q + + Sbjct: 243 PYAQERGLEPLAAAFAVSILSVANAVGRPGAGALSDKIGRAMTMFVLFLIQGITLIAFPH 302 Query: 300 VR-ELAAFYAVAAIFGFIYAGTMPLYSVLIRENFPLRMMGTVIGGTAMAGSLGMATGPLA 358 V L Y AAI GF Y L+ + F + +G G + +G GP+ Sbjct: 303 VALTLITIYICAAIIGFNYGANFSLFPSATGDFFGTKNLGVNYGLVFTSYGVGGLVGPIM 362 Query: 359 GGLIYDTFASYT 370 G ++D SY Sbjct: 363 AGYVFDVTGSYE 374 >AGl3235 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 433 Score = 97.4 bits (241), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 97/363 (26%), Positives = 147/363 (40%), Gaps = 29/363 (7%) Query: 3 NSTYRWVIVAAGGLLGCVAIGGMFSLPVFLQPMARETGWSVTGISSAMTIGFLAMAFTSM 62 N Y WV+ L G M S V +QP+ +E GW + ISSAM + + Sbjct: 16 NLHYGWVVAVTTFLTMLATAGAMGSAGVMIQPLHQEFGWDIADISSAMAVRLVLFGLLGP 75 Query: 63 IWGTLSDRFGPLPVVLTGSVVLAASLALASQVTSLLAFQFVFGALVGAATAAIFAPMMAC 122 + FG VV T ++ + + +T + ++G ++G T + A Sbjct: 76 FAAAFMNHFGIRQVVSTALALIMGGIVASFFMTQVWQLLLLWGVVIGVGTGMTALVLGAT 135 Query: 123 V-TGWFDTHRSLAVSLVSAGMGMAPMTMSPLAAWLISHHDWRTAMLIVSGVVGAIMIPVS 181 V + WF R L + L++A + PL A L + WRTA+ + V+ A MI V Sbjct: 136 VASRWFSKRRGLVIGLMTASNATGQLVFLPLLAALTEAYGWRTALTLSVAVIAAAMILVL 195 Query: 182 FLVRRPPALQGDHAEAVSENGEPP--------------MSLAQALRSPQFIILIATNFFC 227 L+R P+ G A + +PP ++L +P F +L T F C Sbjct: 196 LLMRDHPSDVGLPAYGETAVSKPPKQDHNLLATLASPLVTLKSVSGNPVFWVLFGTFFVC 255 Query: 228 CATHSGPI-IHTVSYAVTCGIPMVAAVTIYSVEGLAGMGGRIAFGLLGDRFGAKRVLV-- 284 + +G I H +S G+ V A +V G+ G I G L DRF + +L Sbjct: 256 GLSTNGLIQTHWISICGDFGMAAVTAAGTLAVIGIFDFFGTIFAGWLSDRFDNRFLLFWF 315 Query: 285 -----LGLLAQAFGALGYVFVRELAAFYAVAAIFGFIYAGTMPLYSVLIRENFPLRMMGT 339 L L+ +F +V + A FY G + T+P L ENF G Sbjct: 316 YGLRGLSLIYLSFSGFSFVELSVFAVFY------GLDWVATVPPTVKLAAENFGREKAGL 369 Query: 340 VIG 342 V G Sbjct: 370 VFG 372