BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0137.0028.p (303 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1135 [R] COG0693 Putative intracellular protease/amidase Pae P... 395 e-110 ECs2705 [R] COG0693 Putative intracellular protease/amidase Ecs ... 357 2e-98 yedU [R] COG0693 Putative intracellular protease/amidase Eco Esc... 356 3e-98 ZyedU [R] COG0693 Putative intracellular protease/amidase EcZ Es... 356 3e-98 SA0509 [R] COG0693 Putative intracellular protease/amidase Sau S... 353 2e-97 >PA1135 [R] COG0693 Putative intracellular protease/amidase Pae Pseudomonas aeruginosa Length = 291 Score = 395 bits (1016), Expect = e-110, Method: Compositional matrix adjust. Identities = 187/289 (64%), Positives = 224/289 (77%), Gaps = 2/289 (0%) Query: 14 SEQSQDKRPVPDPAENNAFFPSPYSLGQFTSAKSDLSGADYPNAYRGGRWKILMIAADER 73 +E+ + P PDPAE+NAFFPSPYSL Q+TSAK+D GADYP Y+GG+ K+LMI DER Sbjct: 3 NERDTSRTPTPDPAEHNAFFPSPYSLSQYTSAKTDFDGADYPTPYKGGK-KVLMIGTDER 61 Query: 74 YLLLQNGTMFSTGNHPVETLLPMYHLDKAGFEFDIATVSGNPVKFELWAFPKEDDAVKSI 133 Y+L+QN +MFSTGNHPVE LLPMYHLDKAGFEFD+AT+SGNPVK E+WA P ED+AVKSI Sbjct: 62 YILMQNASMFSTGNHPVEMLLPMYHLDKAGFEFDVATLSGNPVKLEMWAMPGEDEAVKSI 121 Query: 134 YQKYLARLKQPLKLSDVIESKLGKDSDYIAVFIPGGHGALIGLPESTDVKAALKWALDND 193 Y KYL +LK P KL+D++E + DS Y AVF+PGGHG L G+P S +VK L L D Sbjct: 122 YAKYLPKLKAPRKLADLLEQAVADDSPYAAVFVPGGHGVLAGIPHSREVKRLLNAFLAKD 181 Query: 194 KHIISLCHGPAALLASAVGEAKGDYPFKGYKICAFPDAIDR-TTPDIGYMPGALTWAFGE 252 ++II+LCHGPA LLA AV E DYPFKGY+IC FPDA+D +IGYMPG L W GE Sbjct: 182 RYIITLCHGPACLLAPAVEEKPEDYPFKGYEICVFPDALDTGANLEIGYMPGPLPWLVGE 241 Query: 253 QLQALGVEILNKDITGKTHQDRKLITGDSPFAANNVGKAAAKALLDTLG 301 LQ LGV+ILNK ITG+ H+DRKL+TGDSP A+NN+GK AAK LL+ Sbjct: 242 NLQKLGVKILNKGITGQVHRDRKLLTGDSPLASNNLGKLAAKTLLEAFA 290 >ECs2705 [R] COG0693 Putative intracellular protease/amidase Ecs Escherichia coli O157:H7 Length = 283 Score = 357 bits (916), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 174/290 (60%), Positives = 217/290 (74%), Gaps = 7/290 (2%) Query: 13 MSEQSQDKRPVPDPAENNAFFPSPYSLGQFTSAKSDLSGADYPNAYRGGRWKILMIAADE 72 M+ Q+ K P D AE+NAFFPS YSL Q+TS SDL G DYP YRG + KIL+IAADE Sbjct: 1 MTVQTS-KNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRG-KHKILVIAADE 58 Query: 73 RYLLLQNGTMFSTGNHPVETLLPMYHLDKAGFEFDIATVSGNPVKFELWAFPKEDDAVKS 132 RYL NG +FSTGNHP+ETLLP+YHL AGFEF++AT+SG KFE WA P++D+ V Sbjct: 59 RYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPQKDEKVMP 118 Query: 133 IYQKYLARLKQPLKLSDVIESKLGKDSDYIAVFIPGGHGALIGLPESTDVKAALKWALDN 192 ++++ + + P KL+DV+ S L DS+Y A+F+PGGHGALIGLPES DV AAL+WA+ N Sbjct: 119 FFEQHKSLFRNPKKLADVVAS-LNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKN 177 Query: 193 DKHIISLCHGPAALLASAVGEAKGDYPFKGYKICAFPDAIDRTTPDIGYMPGALTWAFGE 252 D+ +ISLCHGPAA LA GD P GY ICAFPDA D+ TP+IGYMPG LTW FGE Sbjct: 178 DRFVISLCHGPAAFLALR----HGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGE 233 Query: 253 QLQALGVEILNKDITGKTHQDRKLITGDSPFAANNVGKAAAKALLDTLGG 302 +L+ +G+ I+N DITG+ H+DRKL+TGDSPFAAN +GK AA+ +L G Sbjct: 234 ELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQEMLAAYAG 283 >yedU [R] COG0693 Putative intracellular protease/amidase Eco Escherichia coli K12 Length = 283 Score = 356 bits (914), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 174/290 (60%), Positives = 216/290 (74%), Gaps = 7/290 (2%) Query: 13 MSEQSQDKRPVPDPAENNAFFPSPYSLGQFTSAKSDLSGADYPNAYRGGRWKILMIAADE 72 M+ Q+ K P D AE+NAFFPS YSL Q+TS SDL G DYP YRG + KIL+IAADE Sbjct: 1 MTVQTS-KNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRG-KHKILVIAADE 58 Query: 73 RYLLLQNGTMFSTGNHPVETLLPMYHLDKAGFEFDIATVSGNPVKFELWAFPKEDDAVKS 132 RYL NG +FSTGNHP+ETLLP+YHL AGFEF++AT+SG KFE WA P +D+ V Sbjct: 59 RYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMP 118 Query: 133 IYQKYLARLKQPLKLSDVIESKLGKDSDYIAVFIPGGHGALIGLPESTDVKAALKWALDN 192 ++++ + + P KL+DV+ S L DS+Y A+F+PGGHGALIGLPES DV AAL+WA+ N Sbjct: 119 FFEQHKSLFRNPKKLADVVAS-LNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKN 177 Query: 193 DKHIISLCHGPAALLASAVGEAKGDYPFKGYKICAFPDAIDRTTPDIGYMPGALTWAFGE 252 D+ +ISLCHGPAA LA GD P GY ICAFPDA D+ TP+IGYMPG LTW FGE Sbjct: 178 DRFVISLCHGPAAFLALR----HGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGE 233 Query: 253 QLQALGVEILNKDITGKTHQDRKLITGDSPFAANNVGKAAAKALLDTLGG 302 +L+ +G+ I+N DITG+ H+DRKL+TGDSPFAAN +GK AA+ +L G Sbjct: 234 ELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQEMLAAYAG 283 >ZyedU [R] COG0693 Putative intracellular protease/amidase EcZ Escherichia coli O157:H7 EDL933 Length = 283 Score = 356 bits (914), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 174/290 (60%), Positives = 216/290 (74%), Gaps = 7/290 (2%) Query: 13 MSEQSQDKRPVPDPAENNAFFPSPYSLGQFTSAKSDLSGADYPNAYRGGRWKILMIAADE 72 M+ Q+ K P D AE+NAFFPS YSL Q+TS SDL G DYP YRG + KIL+IAADE Sbjct: 1 MTVQTS-KNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRG-KHKILVIAADE 58 Query: 73 RYLLLQNGTMFSTGNHPVETLLPMYHLDKAGFEFDIATVSGNPVKFELWAFPKEDDAVKS 132 RYL NG +FSTGNHP+ETLLP+YHL AGFEF++AT+SG KFE WA P++D+ V Sbjct: 59 RYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPQKDEKVMP 118 Query: 133 IYQKYLARLKQPLKLSDVIESKLGKDSDYIAVFIPGGHGALIGLPESTDVKAALKWALDN 192 ++++ + + P KL+DV+ S L DS+Y A+F+PGGHGALIGLPES DV AAL+WA+ N Sbjct: 119 FFEQHKSLFRNPKKLADVVAS-LNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKN 177 Query: 193 DKHIISLCHGPAALLASAVGEAKGDYPFKGYKICAFPDAIDRTTPDIGYMPGALTWAFGE 252 D+ +ISLCHGPAA LA GD P GY ICAFPDA D+ TP+IGYMPG LTW FGE Sbjct: 178 DRFVISLCHGPAAFLALR----HGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGE 233 Query: 253 QLQALGVEILNKDITGKTHQDRKLITGDSPFAANNVGKAAAKALLDTLGG 302 +L+ +G+ I+N DITG+ H+DRKL+TGDSPFAAN +GK AA +L G Sbjct: 234 ELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAXEMLAAYAG 283 >SA0509 [R] COG0693 Putative intracellular protease/amidase Sau Staphylococcus aureus N315 Length = 292 Score = 353 bits (906), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 159/285 (55%), Positives = 217/285 (76%), Gaps = 3/285 (1%) Query: 20 KRPVPDPAENNAFFPSPYSLGQFTSAKSDLSGADYPNAYRGGRWKILMIAADERYLLLQN 79 K+P PD AE+NAFFPSPYSL Q+T+ K+D G ++ AY+ G+WK+LMIAA+ERY+LL+N Sbjct: 10 KQPTPDKAEDNAFFPSPYSLSQYTAPKTDFDGVEHKGAYKDGKWKVLMIAAEERYVLLEN 69 Query: 80 GTMFSTGNHPVETLLPMYHLDKAGFEFDIATVSGNPVKFELWAFPKEDDAVKSIYQKYLA 139 G MFSTGNHPVE LLP++HL +AGF+ D+AT+SG PVK ELWA P ED+AV S Y K Sbjct: 70 GKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAVISTYNKLKE 129 Query: 140 RLKQPLKLSDVIESKLGKDSDYIAVFIPGGHGALIGLPESTDVKAALKWALDNDKHIISL 199 +LKQP KL+DVI+++LG DSDY++VFIPGGH A++G+ ES DV+ L WALDND+ I++L Sbjct: 130 KLKQPKKLADVIKNELGPDSDYLSVFIPGGHAAVVGISESEDVQQTLDWALDNDRFIVTL 189 Query: 200 CHGPAALLASAVGEAKGDYPFKGYKICAFPDAIDR-TTPDIGYMPGALTWAFGEQLQALG 258 CHGPAALL++ + K P +GY +C FPD++D +IGY+PG L W + L G Sbjct: 190 CHGPAALLSAGLNREKS--PLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVADLLTKQG 247 Query: 259 VEILNKDITGKTHQDRKLITGDSPFAANNVGKAAAKALLDTLGGR 303 ++++N D+TG+T +DRKL+TGDSP A+N +GK A +L+ + + Sbjct: 248 LKVVNDDMTGRTLKDRKLLTGDSPLASNELGKLAVNEMLNAIQNK 292