BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0133.0023.p (310 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr2429 [GEPR] COG0477 Permeases of the major facilitator superf... 300 4e-81 SMb20272 [GEPR] COG0477 Permeases of the major facilitator super... 245 7e-65 AF0367 [GEPR] COG0477 Permeases of the major facilitator superfa... 79 2e-14 BH2694 [GEPR] COG0477 Permeases of the major facilitator superfa... 79 2e-14 AGl3235 [GEPR] COG0477 Permeases of the major facilitator superf... 78 2e-14 >mlr2429 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 400 Score = 300 bits (767), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 160/259 (61%), Positives = 198/259 (76%), Gaps = 6/259 (2%) Query: 6 RLDYGWVVVGAGALMTCVGFGTMLSLAVFLQPISDAMGWSRAGISAAATLDFLCMGFAAF 65 L Y WV+V GALM+CV GTM SLA+FL+P++ WSRAGIS+A TL+FL MG F Sbjct: 2 NLSYRWVIVATGALMSCVAIGTMFSLAIFLEPMALDTQWSRAGISSAMTLNFLVMGLGGF 61 Query: 66 AWGALSDRFGTRIVVLAGSLLLGLGLVTASQAQSLWQFQLCFGVLIGIAAGSFYAPMMAL 125 AWGALSDRFG RIVV G++LLGL LV AS+A SL FQ+ +GVL+G+AA +F+APM+AL Sbjct: 62 AWGALSDRFGARIVVAIGAVLLGLALVVASRAGSLLTFQISYGVLVGLAASAFFAPMIAL 121 Query: 126 ASAWIDKHRSLAVALVSAGMGVSPLTVAPSASWLITAYDWRFAMLVIGIAAWALLIPASF 185 +AW D +RSLAV+LVSAGMGV+P+T++P A WLI+AY+WR AM IGI AW LL+PA Sbjct: 122 TTAWFDTNRSLAVSLVSAGMGVAPMTISPFARWLISAYEWRTAMFDIGIMAWVLLLPAVL 181 Query: 186 LVRPAPQGTDVAIPTAANAPQTE---WTAAQALRTPQFITLALAHFACCAAHSGPIFHMV 242 LVR P+ A+ A+AP E + AQALR+PQFI L L F CCAAHSGPIFHMV Sbjct: 182 LVRQPPKP---AVAAGASAPVAEGAGMSVAQALRSPQFIVLGLTFFTCCAAHSGPIFHMV 238 Query: 243 SYAMVCGIAPLTAVTVYSL 261 SYAM+CG+AP+ AVT+YS+ Sbjct: 239 SYAMLCGVAPMAAVTIYSV 257 >SMb20272 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 402 Score = 245 bits (626), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 134/264 (50%), Positives = 176/264 (66%), Gaps = 1/264 (0%) Query: 8 DYGWVVVGAGALMTCVGFGTMLSLAVFLQPISDAMGWSRAGISAAATLDFLCMGFAAFAW 67 Y WV+V AG L+ C+ G M SL VFL PIS GWS GIS+A T+ F+ M A+ W Sbjct: 5 HYRWVIVAAGGLLGCIAIGAMFSLPVFLVPISRDTGWSVTGISSAMTVGFIAMALASMVW 64 Query: 68 GALSDRFGTRIVVLAGSLLLGLGLVTASQAQSLWQFQLCFGVLIGIAAGSFYAPMMALAS 127 G+ SDR+G R VVL GS LL L +S SL FQL FGV++G A + +APMMA + Sbjct: 65 GSASDRWGPRSVVLIGSALLAASLALSSLVTSLIAFQLVFGVVVGGACAAIFAPMMACVT 124 Query: 128 AWIDKHRSLAVALVSAGMGVSPLTVAPSASWLITAYDWRFAMLVIGIAAWALLIPASFLV 187 W D HRSLAV+LVSAGMG++P+T++P A WL+T YDWR ++ +I A +IPA+ L+ Sbjct: 125 GWFDTHRSLAVSLVSAGMGMAPMTMSPLAGWLVTIYDWRTSLQIIAALAAVTMIPAALLL 184 Query: 188 RPAPQGTDVAIPTAANAPQTEWTAAQALRTPQFITLALAHFACCAAHSGPIFHMVSYAMV 247 R P D +A+ Q + + QALR+PQF+ L L +F CCA HSGPIFH VSYA+ Sbjct: 185 RRPPVLEDTNAVSASEG-QPDMSLGQALRSPQFVILLLTNFFCCATHSGPIFHTVSYAVS 243 Query: 248 CGIAPLTAVTVYSLAGFSGLGGRL 271 CGI + AV++YSL G +G+GGR+ Sbjct: 244 CGIPMMAAVSIYSLEGLAGMGGRV 267 >AF0367 [GEPR] COG0477 Permeases of the major facilitator superfamily Afu Archaeoglobus fulgidus Length = 397 Score = 78.6 bits (192), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 70/252 (27%), Positives = 110/252 (43%), Gaps = 8/252 (3%) Query: 11 WVVVGAGALMTCVGFGTMLSLAVFLQPISDAMGWSRAGISAAATLDFLCMGFAAFAWGAL 70 W+V+ AG L+ + G + + +VF+ P+ + GWS+ S ++ L G Sbjct: 5 WLVIFAGFLLNLM-LGIVYAWSVFVNPLMNTFGWSKTIASLPFSIFLLIFALMMVPAGRT 63 Query: 71 SDRFGTRIVVLAGSLLLGLGLVTA---SQAQSLWQFQLCFGVLIGIAAGSFYAPMMALAS 127 DR G R V + G +LLG+G + + QS + +GV+ G G YA + +A Sbjct: 64 QDRIGPRKVAMLGGVLLGVGFLLSGLIESIQSPYWLIFSYGVIAGAGCGLGYACPIPVAR 123 Query: 128 AWIDKHRSLAVALVSAGMGVSPLTVAPSASWLITAYDWRFAMLVIGIAAWALLIPASFLV 187 W + LA LV G G+S L AP LI Y ++G+ + + A+ L+ Sbjct: 124 KWFPERVGLATGLVVMGFGMSALIFAPLERILIDTYGISTTFYILGVILLIVAVFAASLL 183 Query: 188 RPAPQGTDVAIPTAANAP----QTEWTAAQALRTPQFITLALAHFACCAAHSGPIFHMVS 243 P+ V A + E ++ LR +F L L+ F A I H+ Sbjct: 184 SNPPELPAVQASNPAKVEVVTGKPELGPSEMLRDYRFYVLWLSFFFMALAGLMVIGHIAP 243 Query: 244 YAMVCGIAPLTA 255 YA G+ PL A Sbjct: 244 YAQERGLEPLAA 255 >BH2694 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 418 Score = 78.6 bits (192), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 75/291 (25%), Positives = 119/291 (40%), Gaps = 16/291 (5%) Query: 6 RLDYGWVVVGAGALMTCVGFGTMLSLAVFLQPISDAMGWSRAGISAAATLDFLCMGFAAF 65 ++ YGW++V L G LS F+QP R IS +TL F+ G + Sbjct: 4 KIHYGWIIVAVTFLTFLAVQGVRLSFGAFVQPWETEFSMDRGSISLISTLSFIVYGISQP 63 Query: 66 AWGALSDRFGTRIVVLAGSLLLGLGLVTASQAQSLWQ-FQLCFGVLIGIAAGSFYAPMMA 124 G L DR G R ++ +LL+G+ V + A W F L V+ G+ Sbjct: 64 LIGKLVDRLGARFILSCSTLLVGVSFVLTTMATQPWHLFILYGVVVSIGVGGASNVAATV 123 Query: 125 LASAWIDKHRSLAVALVSAGMGVSPLTVAPSASWLITAYDWRFAMLVIGIAAWALLIP-A 183 + + W +K R LA ++ AG G + + P + LI DW+ ++++G ++ P Sbjct: 124 VITNWFNKKRGLAFGIIEAGFGAGQMILVPGSLMLIQWLDWKATVVILGFFLAVIVFPIV 183 Query: 184 SFLVRPAPQGTDVAIPTAANAPQTEWTAA---------QALRTPQFITLALAHFACCAAH 234 L+R P V P + E + R F L L FA C Sbjct: 184 LLLLRNHPSEKQVE-PIGGVREEEETNTSPNSATFSNWSVFRMRPFWFLVLP-FAICGFT 241 Query: 235 SGPIF--HMVSYAMVCGIAP-LTAVTVYSLAGFSGLGGRLQCWWAAFWCRR 282 + + H++ + G + +T+ V LAGF+ +G L A W R Sbjct: 242 TTGLMDTHLIPLSHDHGFSTSVTSAAVSLLAGFNIVGILLSGVIADRWSSR 292 >AGl3235 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 433 Score = 78.2 bits (191), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 90/319 (28%), Positives = 130/319 (40%), Gaps = 23/319 (7%) Query: 6 RLDYGWVVVGAGALMTCVGFGTMLSLAVFLQPISDAMGWSRAGISAAATLDFLCMGFAAF 65 L YGWVV L G M S V +QP+ GW A IS+A + + G Sbjct: 16 NLHYGWVVAVTTFLTMLATAGAMGSAGVMIQPLHQEFGWDIADISSAMAVRLVLFGLLGP 75 Query: 66 AWGALSDRFGTRIVVLAGSLLLGLGLVTASQAQSLWQFQLCFGVLIGIAAGSFYAPMMA- 124 A + FG R VV L+ G+V + +WQ L +GV+IG+ G + A Sbjct: 76 FAAAFMNHFGIRQVVSTALALIMGGIVASFFMTQVWQLLLLWGVVIGVGTGMTALVLGAT 135 Query: 125 LASAWIDKHRSLAVALVSAGMGVSPLTVAPSASWLITAYDWRFAMLVIGIAAWALLIPAS 184 +AS W K R L + L++A L P + L AY WR A+ + A +I Sbjct: 136 VASRWFSKRRGLVIGLMTASNATGQLVFLPLLAALTEAYGWRTALTLSVAVIAAAMILVL 195 Query: 185 FLVRPAPQGTDVAIP----TAANAPQTE-----WTAAQALRT-------PQFITLALAHF 228 L+R P +DV +P TA + P + T A L T P F L F Sbjct: 196 LLMRDHP--SDVGLPAYGETAVSKPPKQDHNLLATLASPLVTLKSVSGNPVFWVLFGTFF 253 Query: 229 ACCAAHSGPI-FHMVSYAMVCGIAPLTAVTVYSLAGFSGLGGRLQCWWAAFWCRRCRSRP 287 C + +G I H +S G+A +TA ++ G G + W + R +R Sbjct: 254 VCGLSTNGLIQTHWISICGDFGMAAVTAAGTLAVIGIFDFFGTIFAGWLS---DRFDNRF 310 Query: 288 ISRWRSSANSMRCLSCSAS 306 + W + + S S Sbjct: 311 LLFWFYGLRGLSLIYLSFS 329